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The map label for this gene is suhB [H]

Identifier: 126695449

GI number: 126695449

Start: 108642

End: 109442

Strand: Reverse

Name: suhB [H]

Synonym: P9301_01111

Alternate gene names: 126695449

Gene position: 109442-108642 (Counterclockwise)

Preceding gene: 126695450

Following gene: 126695448

Centisome position: 6.67

GC content: 34.58

Gene sequence:

>801_bases
ATGAATCCAACAAATTTAACTAATACGCAGCTACGTAAATTAGATTCTTTATTTGAATTGGTTAGTCAACGCCAAACAAA
AGATTTTGGAAATATTAGCGCCAGTAACAAAGCAGATGGCTCATTATTAACAAGTTGTGATTTATGGAGTGACAAAACAA
TCGTAGATGGCTTAGCTTCAATAGCTCCAGATGAAGGCGTCCTTAGTGAAGAAGGGCAAAAGCTAATTCCAAATTCAAAA
GCTTACTGGGTTGTCGATCCACTCGATGGGACAACAAATTTCGCTGCCGGTATTCCTTACTGGTCTATATCTGTAGCAAG
GTTCGTTGATGGTAAACCAGAATCTTCTTTTTTAATAATTCCTACATTGAAAAAAAAGTTTGTATCCATTAAAGGTAAAG
GGGTTTGGTTAAATAACGAGAAAATCGATCCTAGCCAATATAATCGTCAAAGTGAATGCATTTCTTTATGTAGTAGATCA
ATAAAAATTTTACAAAAAAAACCAAACTCAGTATTTCCTGGCAAGATCAGACTCTTAGGTGTATCGAGTTTAAATCTTAC
GAGTGTAGCGATGGGACAAACTTTTGGAGCAATAGAATCTACCCCTAAGATATGGGATATTGCAGCAGCCTGGCTTCTAT
TAGAAGAACTCAATTGTTCTATAGAGTGGTTAGAAACAAATCCTTTAAATTTAATTCCAGGAGAAGACTTGAGCGATGTT
AATTTTCCATTAATTGCTTGTAGATCTATTGAAAAATTTGAAATTTTAAAGCCATGGGGCAATTTATTATTAGCAAAATA
G

Upstream 100 bases:

>100_bases
ATGAATTAGAAAGATTAACTTTCCTTGATAAAAGTAAAAATTGTTTGAATAGTAATAATACTAAAATTAAAGATGCAGAG
TCTATTTGCAATTTATAAAG

Downstream 100 bases:

>100_bases
TTGCATGATAAATAAAAAATTGCTTGAAAAATTTCTTAATCAGATACAATAAAAATTAAGTAAATAAATAAATATTTGAA
GAAAATAAATATGCAGAGAA

Product: inositol monophosphate family protein

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MNPTNLTNTQLRKLDSLFELVSQRQTKDFGNISASNKADGSLLTSCDLWSDKTIVDGLASIAPDEGVLSEEGQKLIPNSK
AYWVVDPLDGTTNFAAGIPYWSISVARFVDGKPESSFLIIPTLKKKFVSIKGKGVWLNNEKIDPSQYNRQSECISLCSRS
IKILQKKPNSVFPGKIRLLGVSSLNLTSVAMGQTFGAIESTPKIWDIAAAWLLLEELNCSIEWLETNPLNLIPGEDLSDV
NFPLIACRSIEKFEILKPWGNLLLAK

Sequences:

>Translated_266_residues
MNPTNLTNTQLRKLDSLFELVSQRQTKDFGNISASNKADGSLLTSCDLWSDKTIVDGLASIAPDEGVLSEEGQKLIPNSK
AYWVVDPLDGTTNFAAGIPYWSISVARFVDGKPESSFLIIPTLKKKFVSIKGKGVWLNNEKIDPSQYNRQSECISLCSRS
IKILQKKPNSVFPGKIRLLGVSSLNLTSVAMGQTFGAIESTPKIWDIAAAWLLLEELNCSIEWLETNPLNLIPGEDLSDV
NFPLIACRSIEKFEILKPWGNLLLAK
>Mature_266_residues
MNPTNLTNTQLRKLDSLFELVSQRQTKDFGNISASNKADGSLLTSCDLWSDKTIVDGLASIAPDEGVLSEEGQKLIPNSK
AYWVVDPLDGTTNFAAGIPYWSISVARFVDGKPESSFLIIPTLKKKFVSIKGKGVWLNNEKIDPSQYNRQSECISLCSRS
IKILQKKPNSVFPGKIRLLGVSSLNLTSVAMGQTFGAIESTPKIWDIAAAWLLLEELNCSIEWLETNPLNLIPGEDLSDV
NFPLIACRSIEKFEILKPWGNLLLAK

Specific function: Displays a 20-fold higher rate of hydrolysis of the D isoform of inositol 1-phosphate than of the L isoform [H]

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI221625487, Length=205, Percent_Identity=24.390243902439, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI5031789, Length=205, Percent_Identity=24.390243902439, Blast_Score=75, Evalue=6e-14,
Organism=Escherichia coli, GI1788882, Length=194, Percent_Identity=28.3505154639175, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790659, Length=102, Percent_Identity=34.3137254901961, Blast_Score=63, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320493, Length=219, Percent_Identity=30.1369863013699, Blast_Score=72, Evalue=7e-14,
Organism=Drosophila melanogaster, GI21357329, Length=212, Percent_Identity=25.9433962264151, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24664922, Length=192, Percent_Identity=28.6458333333333, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21357303, Length=234, Percent_Identity=25.6410256410256, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24664926, Length=225, Percent_Identity=26.6666666666667, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 29359; Mature: 29359

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPTNLTNTQLRKLDSLFELVSQRQTKDFGNISASNKADGSLLTSCDLWSDKTIVDGLAS
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHH
IAPDEGVLSEEGQKLIPNSKAYWVVDPLDGTTNFAAGIPYWSISVARFVDGKPESSFLII
CCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHEEEEEHCCCCCCCCEEEE
PTLKKKFVSIKGKGVWLNNEKIDPSQYNRQSECISLCSRSIKILQKKPNSVFPGKIRLLG
ECCCCCEEEECCCEEEECCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
VSSLNLTSVAMGQTFGAIESTPKIWDIAAAWLLLEELNCSIEWLETNPLNLIPGEDLSDV
ECCCCCHHHHHCCHHCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCEEECCCCCCCC
NFPLIACRSIEKFEILKPWGNLLLAK
CCCEEEECCCCHHEEECCCCCEEECC
>Mature Secondary Structure
MNPTNLTNTQLRKLDSLFELVSQRQTKDFGNISASNKADGSLLTSCDLWSDKTIVDGLAS
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHH
IAPDEGVLSEEGQKLIPNSKAYWVVDPLDGTTNFAAGIPYWSISVARFVDGKPESSFLII
CCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHEEEEEHCCCCCCCCEEEE
PTLKKKFVSIKGKGVWLNNEKIDPSQYNRQSECISLCSRSIKILQKKPNSVFPGKIRLLG
ECCCCCEEEECCCEEEECCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
VSSLNLTSVAMGQTFGAIESTPKIWDIAAAWLLLEELNCSIEWLETNPLNLIPGEDLSDV
ECCCCCHHHHHCCHHCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCEEECCCCCCCC
NFPLIACRSIEKFEILKPWGNLLLAK
CCCEEEECCCCHHEEECCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9720201; 10360571; 10508089 [H]