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The map label for this gene is gltC [H]

Identifier: 126701266

GI number: 126701266

Start: 4248297

End: 4249178

Strand: Direct

Name: gltC [H]

Synonym: CD3639

Alternate gene names: 126701266

Gene position: 4248297-4249178 (Clockwise)

Preceding gene: 126701244

Following gene: 126701280

Centisome position: 99.02

GC content: 28.0

Gene sequence:

>882_bases
TTGAATACTAAACAATTAGAATATTTTATATCTGTAGCAGAAAATCTAAGTTTTACCAAAACAGCAGAAAAATTTTATAT
TTCTCAAACTGCTGTTACACAGCAAATAAAAGCTTTAGAAGAACAAATAAATGTAACTCTATTTACAAGAAGTAAACGTC
ATGTTGAACTAACACCAGCTGGAAAAGTTTTTTTATCTGAGGCACGTACTATAATAAAAAATATCAATGATGCTATTGCA
AAAACACAACAATTTGCACATGGTTTTTTTGGAACTTTGAGCATTGGAACCTTAATAGGATATGAAAAAAACAAACTTCA
ACAATATTTAAAAGAATTTTCTAACACATACCCTAATATATCTATGGATATTTGTACTAATGAGATAACCGAACTTTTAA
ACTTAGTAAAAAATAATTCTATGGACCTCGCTTTTGTTATTAATCCAGAAAATCAACCATTAAAAGATTTTGAATATAAA
ACTGTAGAAAGATATTCTTTGGTAGCTCTTTTACCTCCTGGTCATCCACTTTACAATGAGGATTCTATCGATTTAATTGA
ATTACAACATGATAAATTTATTTTTGTAAAAGAAACAGGGGATGAGTATGGACAAAAGTCAATGATACAGAATAGATATC
GTGAAGCAGGGTTTGTACCTAATGTGGTACAACGTTCAAATAATCTTAATACTATTGAATCATTGGTATCTTCTAACATG
GGAATATCCATTTTACCTTCATTTTGTGTTACAGATACAATGATAGAACGTGATATTGCAATAGTACCTATAAAAGAAGT
AGAAAATAGAATTGAAGTTGTAGTTGTATGGAATAAAAAAAATACAAATCCAGCATTAGAAAAGTTCATTTCTATAATAT
AA

Upstream 100 bases:

>100_bases
TTCTAATATTCTTTAAAAGTAAATTTTCTTATACTATAATAAGCTTTAATTATAGATAAATAAGGTTTACAAACAATCAA
GTTTAAATAGGGGTGATTAT

Downstream 100 bases:

>100_bases
AATTAATCAATATTAACGATAAAAATAGCATTAACCATTTTTTCTATAGTTAATGCTATTTTCTACTATTTTATTATTTA
ACTTTTAATTTAATATTTAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MNTKQLEYFISVAENLSFTKTAEKFYISQTAVTQQIKALEEQINVTLFTRSKRHVELTPAGKVFLSEARTIIKNINDAIA
KTQQFAHGFFGTLSIGTLIGYEKNKLQQYLKEFSNTYPNISMDICTNEITELLNLVKNNSMDLAFVINPENQPLKDFEYK
TVERYSLVALLPPGHPLYNEDSIDLIELQHDKFIFVKETGDEYGQKSMIQNRYREAGFVPNVVQRSNNLNTIESLVSSNM
GISILPSFCVTDTMIERDIAIVPIKEVENRIEVVVVWNKKNTNPALEKFISII

Sequences:

>Translated_293_residues
MNTKQLEYFISVAENLSFTKTAEKFYISQTAVTQQIKALEEQINVTLFTRSKRHVELTPAGKVFLSEARTIIKNINDAIA
KTQQFAHGFFGTLSIGTLIGYEKNKLQQYLKEFSNTYPNISMDICTNEITELLNLVKNNSMDLAFVINPENQPLKDFEYK
TVERYSLVALLPPGHPLYNEDSIDLIELQHDKFIFVKETGDEYGQKSMIQNRYREAGFVPNVVQRSNNLNTIESLVSSNM
GISILPSFCVTDTMIERDIAIVPIKEVENRIEVVVVWNKKNTNPALEKFISII
>Mature_293_residues
MNTKQLEYFISVAENLSFTKTAEKFYISQTAVTQQIKALEEQINVTLFTRSKRHVELTPAGKVFLSEARTIIKNINDAIA
KTQQFAHGFFGTLSIGTLIGYEKNKLQQYLKEFSNTYPNISMDICTNEITELLNLVKNNSMDLAFVINPENQPLKDFEYK
TVERYSLVALLPPGHPLYNEDSIDLIELQHDKFIFVKETGDEYGQKSMIQNRYREAGFVPNVVQRSNNLNTIESLVSSNM
GISILPSFCVTDTMIERDIAIVPIKEVENRIEVVVVWNKKNTNPALEKFISII

Specific function: Positive regulator of glutamate biosynthesis (gltAB genes). Negatively regulates its own expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=294, Percent_Identity=31.6326530612245, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1788887, Length=295, Percent_Identity=27.1186440677966, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI2367136, Length=294, Percent_Identity=23.8095238095238, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI157672245, Length=263, Percent_Identity=24.7148288973384, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1790399, Length=281, Percent_Identity=23.8434163701068, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1787530, Length=272, Percent_Identity=26.4705882352941, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI145693105, Length=291, Percent_Identity=26.8041237113402, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788748, Length=249, Percent_Identity=24.4979919678715, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787806, Length=297, Percent_Identity=23.2323232323232, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788297, Length=276, Percent_Identity=25.3623188405797, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI145693193, Length=123, Percent_Identity=32.520325203252, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787601, Length=266, Percent_Identity=23.6842105263158, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787949, Length=172, Percent_Identity=25.5813953488372, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788296, Length=251, Percent_Identity=23.1075697211155, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1790208, Length=301, Percent_Identity=22.2591362126246, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789173, Length=119, Percent_Identity=32.7731092436975, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789204, Length=257, Percent_Identity=22.9571984435798, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789639, Length=124, Percent_Identity=28.2258064516129, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787589, Length=122, Percent_Identity=29.5081967213115, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787128, Length=139, Percent_Identity=28.0575539568345, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33460; Mature: 33460

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTKQLEYFISVAENLSFTKTAEKFYISQTAVTQQIKALEEQINVTLFTRSKRHVELTPA
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEECCC
GKVFLSEARTIIKNINDAIAKTQQFAHGFFGTLSIGTLIGYEKNKLQQYLKEFSNTYPNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCE
SMDICTNEITELLNLVKNNSMDLAFVINPENQPLKDFEYKTVERYSLVALLPPGHPLYNE
EEHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHEEEEEEEEECCCCCCCCC
DSIDLIELQHDKFIFVKETGDEYGQKSMIQNRYREAGFVPNVVQRSNNLNTIESLVSSNM
CCCEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHCCC
GISILPSFCVTDTMIERDIAIVPIKEVENRIEVVVVWNKKNTNPALEKFISII
CCEECCHHHHHHHHHHCCEEEEEHHHHCCCEEEEEEECCCCCCHHHHHHHHCC
>Mature Secondary Structure
MNTKQLEYFISVAENLSFTKTAEKFYISQTAVTQQIKALEEQINVTLFTRSKRHVELTPA
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEECCC
GKVFLSEARTIIKNINDAIAKTQQFAHGFFGTLSIGTLIGYEKNKLQQYLKEFSNTYPNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCE
SMDICTNEITELLNLVKNNSMDLAFVINPENQPLKDFEYKTVERYSLVALLPPGHPLYNE
EEHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHEEEEEEEEECCCCCCCCC
DSIDLIELQHDKFIFVKETGDEYGQKSMIQNRYREAGFVPNVVQRSNNLNTIESLVSSNM
CCCEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHCCC
GISILPSFCVTDTMIERDIAIVPIKEVENRIEVVVVWNKKNTNPALEKFISII
CCEECCHHHHHHHHHHCCEEEEEHHHHCCCEEEEEEECCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2548995; 9384377 [H]