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The map label for this gene is rlmL [H]

Identifier: 126701208

GI number: 126701208

Start: 4180960

End: 4181832

Strand: Direct

Name: rlmL [H]

Synonym: CD3581

Alternate gene names: 126701208

Gene position: 4180960-4181832 (Clockwise)

Preceding gene: 126701206

Following gene: 126701209

Centisome position: 97.45

GC content: 33.68

Gene sequence:

>873_bases
ATGTTATTATTAGCAGATAAATGGAAAGATTATGAACTTATAGATATGGGAAATGGAGAAAAATTAGAACGTTGGGGAAG
TTATGTACTTAGAAGACCAGACCCACAGGTTGTATGGCCAATGGAATCTGAATGGGCTTTATGGAAAAACCCTCATGGAC
ATTATCACAGAAGCAATAAAGGTGGAGGTCAATGGGAACACAAAAAAAGATATCCAGAACAATGGACTATAAATTATAAA
AACTTAAAGTTTCACATTAAACCAACTGGCTTTAAACATACTGGATTATTCCCAGAGCAAGCAGCTAACTGGGATTGGAT
GATAGAGAAAATAAAGAAAGCTAACAGACCTATAAAAGTGTTGAATCTTTTTGCATATACAGGTGGAGCTACTGTAGCAT
GTGCATCTGCTGGTGCAGAAGTATGTCATGTTGATGCTGCAAAAGGTATGGTTAATTGGGCAAAAGAAAATATAGAATTA
TCAGGTCTTAAAAATCAAACAGTAAGATTTATAGTGGATGATGTTGTAAAGTTTGTTGAAAGAGAAATAAGAAGAGGTAA
AAAATATGATGCAATAATAATGGACCCTCCTTCTTATGGAAGAGGTCCTAAAGGAGAAGTATGGCAAATAGAAGAAAAGT
TATACAGTTTTGTAGATTTATGTATGGGAGTTTTATCAGATAACCCTTTATTTTTCTTAATTAATTCTTATACAACAGGA
TTTTCTCCAATAGTTCTTGAAAATGTATTGTCTACAACAATAGGTAAAAAGACAAATACAGGAGATATATACGGTGGGGA
ATTAGGAATACCAGCTTCCAGAGATGGTAAGATACTTCCTTGTGGTATATTTGGAAGATGGGAGAAAAAATAA

Upstream 100 bases:

>100_bases
ATGGTAAATGTAAAGAATAGAAAGTATCTAAAACAGCAAAAAATGACTAATTTTGTGGTATAATACATAGGATTGAGAGT
TATTTTATAGGAGGAAAAAT

Downstream 100 bases:

>100_bases
TGATAAAAGTCATATATGAAGATAACCATTTATTAGTTGTAGAAAAACCAGTTAACATATTGTCTCAAGGAGATAATACT
AATGATAAAGATATGGTAAA

Product: hypothetical protein

Products: NA

Alternate protein names: 23S rRNA m2G2445 methyltransferase; rRNA (guanine-N(2)-)-methyltransferase rlmL [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MLLLADKWKDYELIDMGNGEKLERWGSYVLRRPDPQVVWPMESEWALWKNPHGHYHRSNKGGGQWEHKKRYPEQWTINYK
NLKFHIKPTGFKHTGLFPEQAANWDWMIEKIKKANRPIKVLNLFAYTGGATVACASAGAEVCHVDAAKGMVNWAKENIEL
SGLKNQTVRFIVDDVVKFVEREIRRGKKYDAIIMDPPSYGRGPKGEVWQIEEKLYSFVDLCMGVLSDNPLFFLINSYTTG
FSPIVLENVLSTTIGKKTNTGDIYGGELGIPASRDGKILPCGIFGRWEKK

Sequences:

>Translated_290_residues
MLLLADKWKDYELIDMGNGEKLERWGSYVLRRPDPQVVWPMESEWALWKNPHGHYHRSNKGGGQWEHKKRYPEQWTINYK
NLKFHIKPTGFKHTGLFPEQAANWDWMIEKIKKANRPIKVLNLFAYTGGATVACASAGAEVCHVDAAKGMVNWAKENIEL
SGLKNQTVRFIVDDVVKFVEREIRRGKKYDAIIMDPPSYGRGPKGEVWQIEEKLYSFVDLCMGVLSDNPLFFLINSYTTG
FSPIVLENVLSTTIGKKTNTGDIYGGELGIPASRDGKILPCGIFGRWEKK
>Mature_290_residues
MLLLADKWKDYELIDMGNGEKLERWGSYVLRRPDPQVVWPMESEWALWKNPHGHYHRSNKGGGQWEHKKRYPEQWTINYK
NLKFHIKPTGFKHTGLFPEQAANWDWMIEKIKKANRPIKVLNLFAYTGGATVACASAGAEVCHVDAAKGMVNWAKENIEL
SGLKNQTVRFIVDDVVKFVEREIRRGKKYDAIIMDPPSYGRGPKGEVWQIEEKLYSFVDLCMGVLSDNPLFFLINSYTTG
FSPIVLENVLSTTIGKKTNTGDIYGGELGIPASRDGKILPCGIFGRWEKK

Specific function: Specifically methylates the guanosine in position 2445 (m2G2445) of 23S rRNA [H]

COG id: COG1092

COG function: function code R; Predicted SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 THUMP domain [H]

Homologues:

Organism=Escherichia coli, GI145693111, Length=82, Percent_Identity=39.0243902439024, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR000241
- InterPro:   IPR017244
- InterPro:   IPR019614
- InterPro:   IPR004114 [H]

Pfam domain/function: PF10672 Methyltrans_SAM; PF02926 THUMP; PF01170 UPF0020 [H]

EC number: =2.1.1.173 [H]

Molecular weight: Translated: 33124; Mature: 33124

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLLADKWKDYELIDMGNGEKLERWGSYVLRRPDPQVVWPMESEWALWKNPHGHYHRSNK
CEEECCCCCCEEEEECCCCHHHHHHHHHHEECCCCCEEECCCCCCEEECCCCCCCCCCCC
GGGQWEHKKRYPEQWTINYKNLKFHIKPTGFKHTGLFPEQAANWDWMIEKIKKANRPIKV
CCCCCHHHHCCCCEEEEEEEEEEEEECCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCEEE
LNLFAYTGGATVACASAGAEVCHVDAAKGMVNWAKENIELSGLKNQTVRFIVDDVVKFVE
EEEEEECCCCEEEEECCCCCEEEEHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHH
REIRRGKKYDAIIMDPPSYGRGPKGEVWQIEEKLYSFVDLCMGVLSDNPLFFLINSYTTG
HHHHCCCCCCEEEECCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
FSPIVLENVLSTTIGKKTNTGDIYGGELGIPASRDGKILPCGIFGRWEKK
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCC
>Mature Secondary Structure
MLLLADKWKDYELIDMGNGEKLERWGSYVLRRPDPQVVWPMESEWALWKNPHGHYHRSNK
CEEECCCCCCEEEEECCCCHHHHHHHHHHEECCCCCEEECCCCCCEEECCCCCCCCCCCC
GGGQWEHKKRYPEQWTINYKNLKFHIKPTGFKHTGLFPEQAANWDWMIEKIKKANRPIKV
CCCCCHHHHCCCCEEEEEEEEEEEEECCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCEEE
LNLFAYTGGATVACASAGAEVCHVDAAKGMVNWAKENIELSGLKNQTVRFIVDDVVKFVE
EEEEEECCCCEEEEECCCCCEEEEHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHH
REIRRGKKYDAIIMDPPSYGRGPKGEVWQIEEKLYSFVDLCMGVLSDNPLFFLINSYTTG
HHHHCCCCCCEEEECCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
FSPIVLENVLSTTIGKKTNTGDIYGGELGIPASRDGKILPCGIFGRWEKK
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA