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The map label for this gene is stc [H]

Identifier: 126700314

GI number: 126700314

Start: 3119409

End: 3121433

Strand: Direct

Name: stc [H]

Synonym: CD2700

Alternate gene names: 126700314

Gene position: 3119409-3121433 (Clockwise)

Preceding gene: 126700306

Following gene: 126700318

Centisome position: 72.71

GC content: 26.17

Gene sequence:

>2025_bases
ATGGATAAAAAGAAGTTAATCCTTATAACATATGATAAATTGAATAGTGACCACTACAAAGAAGAATTAACAAACTTTTT
TGGAGACGAAATAATCATAGAAACACAAAATATACTTGATGGAATAAAAGAAAATTTAGAGGGAGATGTAGTGCTTTCTC
TATCACCTTTAACTAGTAATTTTTTAATAAAACATTTTAAGGAAGATATTGAAATTATTCATGGAACGAAAGCACTTTCA
AAACTTGGATATGAAAAAATGATGAAACTACCTCCAGGTACAAAATCGTTACTTATGACAACCAATAAAACTTCAGCATT
TGAGATGGCTACTTATCTATATAAAATTGGTATAAATCATATAGATTTTGTACCGACATATCCAGATTGTGATGAAATAT
ATGATTTAGATACAGCTATAACACCAGGTCAGATTAGATTTATACCAAAATACATAAAAAATATTGTTGATTTAGGTTGG
AGAAAAATCTCATTAGATACATATATGTCATTATTAGTAGTATTAAAACTAAAAAATGAGAAATTTATAGAAAAACTATA
CAAATTGTCCAAGGAGACACTAAGTCATGATTTCTTAAATACATCATTAGATAATATATCTAAATTAAAAACTATACTTT
ACATGACCATTGATGAAATAGGTGATGGTCTAATATTTTTCAATACCTTTAACAAGGTTACTTTTGTAAATAAGTCTTTA
CTTAATATGTTGGAACTAGATGAAAAACTTATAAAATCACCTTCCTTAATGGAATATATGCCAAAGAGTTTCTTAGATAA
AATTACAAAGAACTTAAATATAGATAATATGATTATATACATAGACGAAATAGATAAAAAATTCATACTTTCTAAAAAAC
CATTTTATCTTTATAAAAATATAGAGGGTTGCTTAATTACATTAAAAGATGTAAACAATATAGAAATATTAGAACAAAAA
ATAAGAAGTGATTCTGTCAAAAGAGGTTATGTAGCTAAATATAAATTTAATAATATTATTGGAAATAGTTCTATTATAAA
AGATTGTATTAAAAAGGCAAAAAAAATGGCTCTTACAGATAATCCTATATTAATAACAGGTGAAACAGGAACAGGTAAAG
AAGCCTTTACTCAGTCAATACACAATCATTCAAATAGAAAAAATAAACCTTTTGTAGCAATAAATTGTGCTTCATTACCA
AGTGAATTACTTGAAAGTGAACTATTTGGATATGAAGATGGTTCTTTTACTGGAGCAAAAAAAGGTGGAAAAAAAGGATT
ATTCGAATTAGCTCACACTGGCACTATATTTTTAGATGAGATAGGAGATATGCCACATGATTTACAGGTTAAACTTTTAA
GAGTCTTACAAGAAAAAGAAATTAGAAAAATTGGTGGTACAAGTATTATTCCAATTGATGTGAGAATATTAGCTGCCACA
AATAAAGATTTAGAGAAATTAATTATAGAAAATAAATTTAGGATGGATTTATTTTATAGGATAAGTATGTTCACTTTAGA
TTTACCTCCTCTTAGAAAGAGATTAGAAGATATACCTCTTCTTTTAGAATCATTTTTAAAAGAACTTCCCTATAAAAACA
TAAAACTCGATAAGAGTCTTTTAGAAGCTTTAAATTCATACACTTGGATGGGGAATATTAGAGAACTGAGAAATTGTGTT
GAATATATGGCTTACATGGGTTCCAATTATCTTACAATAAATGATTTACCTCAAAACATATCTTCAAAATTAAATAATAA
TCATATGTCAAGTAATATGTCCATATTCAATGATTTAAACCAATATGACAAAAACATATGCATTTCTATCCTAAAATCAT
TGCACATGAAACCAATGGGGAGGACAAAGTTAATGAAATTTATGGAATATAATGTCACAGAATACGAAGTAAGAAATATG
CTAGAATATTTGACACGTAATGGATACTTAATTTCTAGTAAAGGAAGAAAAGGCTCATCAATAACTGAGAAAGGCATAAA
AATAATAGAAAATAATATAATTTAA

Upstream 100 bases:

>100_bases
ATCAAATATATAAATTTATACTACTATTTGTTGTATAATATAACTTGCCTTATACTTTAAATACTTTAAAAATAAATACT
ATTTTGTTAGGAGAAATAAA

Downstream 100 bases:

>100_bases
ACCTATAGTAATTCATCTTTACTTTATCAAAATTTATATATAATTATAATTTTTTATTTTTCTATAAATTTTTTATAAAA
TAATAAAACTTATTTATATT

Product: sigma54-interacting regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 674; Mature: 674

Protein sequence:

>674_residues
MDKKKLILITYDKLNSDHYKEELTNFFGDEIIIETQNILDGIKENLEGDVVLSLSPLTSNFLIKHFKEDIEIIHGTKALS
KLGYEKMMKLPPGTKSLLMTTNKTSAFEMATYLYKIGINHIDFVPTYPDCDEIYDLDTAITPGQIRFIPKYIKNIVDLGW
RKISLDTYMSLLVVLKLKNEKFIEKLYKLSKETLSHDFLNTSLDNISKLKTILYMTIDEIGDGLIFFNTFNKVTFVNKSL
LNMLELDEKLIKSPSLMEYMPKSFLDKITKNLNIDNMIIYIDEIDKKFILSKKPFYLYKNIEGCLITLKDVNNIEILEQK
IRSDSVKRGYVAKYKFNNIIGNSSIIKDCIKKAKKMALTDNPILITGETGTGKEAFTQSIHNHSNRKNKPFVAINCASLP
SELLESELFGYEDGSFTGAKKGGKKGLFELAHTGTIFLDEIGDMPHDLQVKLLRVLQEKEIRKIGGTSIIPIDVRILAAT
NKDLEKLIIENKFRMDLFYRISMFTLDLPPLRKRLEDIPLLLESFLKELPYKNIKLDKSLLEALNSYTWMGNIRELRNCV
EYMAYMGSNYLTINDLPQNISSKLNNNHMSSNMSIFNDLNQYDKNICISILKSLHMKPMGRTKLMKFMEYNVTEYEVRNM
LEYLTRNGYLISSKGRKGSSITEKGIKIIENNII

Sequences:

>Translated_674_residues
MDKKKLILITYDKLNSDHYKEELTNFFGDEIIIETQNILDGIKENLEGDVVLSLSPLTSNFLIKHFKEDIEIIHGTKALS
KLGYEKMMKLPPGTKSLLMTTNKTSAFEMATYLYKIGINHIDFVPTYPDCDEIYDLDTAITPGQIRFIPKYIKNIVDLGW
RKISLDTYMSLLVVLKLKNEKFIEKLYKLSKETLSHDFLNTSLDNISKLKTILYMTIDEIGDGLIFFNTFNKVTFVNKSL
LNMLELDEKLIKSPSLMEYMPKSFLDKITKNLNIDNMIIYIDEIDKKFILSKKPFYLYKNIEGCLITLKDVNNIEILEQK
IRSDSVKRGYVAKYKFNNIIGNSSIIKDCIKKAKKMALTDNPILITGETGTGKEAFTQSIHNHSNRKNKPFVAINCASLP
SELLESELFGYEDGSFTGAKKGGKKGLFELAHTGTIFLDEIGDMPHDLQVKLLRVLQEKEIRKIGGTSIIPIDVRILAAT
NKDLEKLIIENKFRMDLFYRISMFTLDLPPLRKRLEDIPLLLESFLKELPYKNIKLDKSLLEALNSYTWMGNIRELRNCV
EYMAYMGSNYLTINDLPQNISSKLNNNHMSSNMSIFNDLNQYDKNICISILKSLHMKPMGRTKLMKFMEYNVTEYEVRNM
LEYLTRNGYLISSKGRKGSSITEKGIKIIENNII
>Mature_674_residues
MDKKKLILITYDKLNSDHYKEELTNFFGDEIIIETQNILDGIKENLEGDVVLSLSPLTSNFLIKHFKEDIEIIHGTKALS
KLGYEKMMKLPPGTKSLLMTTNKTSAFEMATYLYKIGINHIDFVPTYPDCDEIYDLDTAITPGQIRFIPKYIKNIVDLGW
RKISLDTYMSLLVVLKLKNEKFIEKLYKLSKETLSHDFLNTSLDNISKLKTILYMTIDEIGDGLIFFNTFNKVTFVNKSL
LNMLELDEKLIKSPSLMEYMPKSFLDKITKNLNIDNMIIYIDEIDKKFILSKKPFYLYKNIEGCLITLKDVNNIEILEQK
IRSDSVKRGYVAKYKFNNIIGNSSIIKDCIKKAKKMALTDNPILITGETGTGKEAFTQSIHNHSNRKNKPFVAINCASLP
SELLESELFGYEDGSFTGAKKGGKKGLFELAHTGTIFLDEIGDMPHDLQVKLLRVLQEKEIRKIGGTSIIPIDVRILAAT
NKDLEKLIIENKFRMDLFYRISMFTLDLPPLRKRLEDIPLLLESFLKELPYKNIKLDKSLLEALNSYTWMGNIRELRNCV
EYMAYMGSNYLTINDLPQNISSKLNNNHMSSNMSIFNDLNQYDKNICISILKSLHMKPMGRTKLMKFMEYNVTEYEVRNM
LEYLTRNGYLISSKGRKGSSITEKGIKIIENNII

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=323, Percent_Identity=40.8668730650155, Blast_Score=244, Evalue=9e-66,
Organism=Escherichia coli, GI1789233, Length=391, Percent_Identity=37.3401534526854, Blast_Score=242, Evalue=6e-65,
Organism=Escherichia coli, GI87082117, Length=229, Percent_Identity=50.2183406113537, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI1786524, Length=271, Percent_Identity=44.280442804428, Blast_Score=239, Evalue=6e-64,
Organism=Escherichia coli, GI1789087, Length=231, Percent_Identity=48.0519480519481, Blast_Score=228, Evalue=1e-60,
Organism=Escherichia coli, GI1788905, Length=235, Percent_Identity=45.1063829787234, Blast_Score=221, Evalue=9e-59,
Organism=Escherichia coli, GI1790299, Length=247, Percent_Identity=42.5101214574899, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1790437, Length=250, Percent_Identity=42.4, Blast_Score=213, Evalue=4e-56,
Organism=Escherichia coli, GI1787583, Length=281, Percent_Identity=36.6548042704626, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI87082152, Length=231, Percent_Identity=43.2900432900433, Blast_Score=190, Evalue=3e-49,
Organism=Escherichia coli, GI87081872, Length=253, Percent_Identity=40.7114624505929, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI87081858, Length=384, Percent_Identity=27.0833333333333, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1789828, Length=263, Percent_Identity=32.6996197718631, Blast_Score=136, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 77606; Mature: 77606

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKKKLILITYDKLNSDHYKEELTNFFGDEIIIETQNILDGIKENLEGDVVLSLSPLTSN
CCCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCEEEEECCCHHH
FLIKHFKEDIEIIHGTKALSKLGYEKMMKLPPGTKSLLMTTNKTSAFEMATYLYKIGINH
HHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCC
IDFVPTYPDCDEIYDLDTAITPGQIRFIPKYIKNIVDLGWRKISLDTYMSLLVVLKLKNE
EECCCCCCCHHHHHCCCCCCCCCCEEEHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCH
KFIEKLYKLSKETLSHDFLNTSLDNISKLKTILYMTIDEIGDGLIFFNTFNKVTFVNKSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHH
LNMLELDEKLIKSPSLMEYMPKSFLDKITKNLNIDNMIIYIDEIDKKFILSKKPFYLYKN
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHCCCCCEEEEEC
IEGCLITLKDVNNIEILEQKIRSDSVKRGYVAKYKFNNIIGNSSIIKDCIKKAKKMALTD
CCCEEEEEECCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHEECC
NPILITGETGTGKEAFTQSIHNHSNRKNKPFVAINCASLPSELLESELFGYEDGSFTGAK
CCEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEEHHHCHHHHHHHHHCCCCCCCCCCCC
KGGKKGLFELAHTGTIFLDEIGDMPHDLQVKLLRVLQEKEIRKIGGTSIIPIDVRILAAT
CCCCCCHHHHHCCCEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEC
NKDLEKLIIENKFRMDLFYRISMFTLDLPPLRKRLEDIPLLLESFLKELPYKNIKLDKSL
CHHHHHHHHCCCHHHHHEEEEEHEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
LEALNSYTWMGNIRELRNCVEYMAYMGSNYLTINDLPQNISSKLNNNHMSSNMSIFNDLN
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHCCCCCCCCHHHHHHHH
QYDKNICISILKSLHMKPMGRTKLMKFMEYNVTEYEVRNMLEYLTRNGYLISSKGRKGSS
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCCCCCCC
ITEKGIKIIENNII
HHHHHHHHHHCCCC
>Mature Secondary Structure
MDKKKLILITYDKLNSDHYKEELTNFFGDEIIIETQNILDGIKENLEGDVVLSLSPLTSN
CCCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCEEEEECCCHHH
FLIKHFKEDIEIIHGTKALSKLGYEKMMKLPPGTKSLLMTTNKTSAFEMATYLYKIGINH
HHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCC
IDFVPTYPDCDEIYDLDTAITPGQIRFIPKYIKNIVDLGWRKISLDTYMSLLVVLKLKNE
EECCCCCCCHHHHHCCCCCCCCCCEEEHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCH
KFIEKLYKLSKETLSHDFLNTSLDNISKLKTILYMTIDEIGDGLIFFNTFNKVTFVNKSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHH
LNMLELDEKLIKSPSLMEYMPKSFLDKITKNLNIDNMIIYIDEIDKKFILSKKPFYLYKN
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHCCCCCEEEEEC
IEGCLITLKDVNNIEILEQKIRSDSVKRGYVAKYKFNNIIGNSSIIKDCIKKAKKMALTD
CCCEEEEEECCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHEECC
NPILITGETGTGKEAFTQSIHNHSNRKNKPFVAINCASLPSELLESELFGYEDGSFTGAK
CCEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEEHHHCHHHHHHHHHCCCCCCCCCCCC
KGGKKGLFELAHTGTIFLDEIGDMPHDLQVKLLRVLQEKEIRKIGGTSIIPIDVRILAAT
CCCCCCHHHHHCCCEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEC
NKDLEKLIIENKFRMDLFYRISMFTLDLPPLRKRLEDIPLLLESFLKELPYKNIKLDKSL
CHHHHHHHHCCCHHHHHEEEEEHEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
LEALNSYTWMGNIRELRNCVEYMAYMGSNYLTINDLPQNISSKLNNNHMSSNMSIFNDLN
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHCCCCCCCCHHHHHHHH
QYDKNICISILKSLHMKPMGRTKLMKFMEYNVTEYEVRNMLEYLTRNGYLISSKGRKGSS
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCCCCCCC
ITEKGIKIIENNII
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA