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The map label for this gene is ypdF [C]

Identifier: 126700227

GI number: 126700227

Start: 3020012

End: 3021088

Strand: Direct

Name: ypdF [C]

Synonym: CD2613

Alternate gene names: 126700227

Gene position: 3020012-3021088 (Clockwise)

Preceding gene: 126700223

Following gene: 126700229

Centisome position: 70.39

GC content: 31.57

Gene sequence:

>1077_bases
ATGAAAGCTCAAAGATTAAATGCTGTACTTGAACAAATGAAAAAAGATGATATTTCTCAAATGTTAGTAAGTGACCCTAC
TTCTATATTTTATCTTACAGGAGTACTAATCCATCCAGGCGAAAGACTATTAGCATTATACTTAAATTTAAATGGCAATA
ATAAATTATTTATAAATGAATTATTCCCAGTTTCAGAAGATTTAGGTGTTGAAATGGTTTGGTTTAATGATACTCAAAAT
CCAGTAGAAATAATAACTGAACATATAGACAAAAATGCTACTATGGGTGTTGATAAAAACTGGCCAGCTAGATTCTTATT
AAACTTAATAGAATTAGGTGGAGGAAGTAAGTTTGTAAATTCATCTTATATAATAGATACTTTAAGAATGTGTAAAGATG
AAGAAGAAAAAGAGTTAATGAGAATAGCTTCAAAATTAAATGACAAGGCTATGGAACAACTTAAAGCTACTGTTTCTGGT
GAACTTACAGAAAAACAACTTGTTGGTAAATTATCTAAAATATATGAAGACCTAGGTACTGATGGATTTTCATTTGACCC
TATTATAGGTTTTGGACCTAATGGAGCTAATCCACATGGTGAACCTGGAAATGCACTTGTGAAACCAGGAGATGCAATAA
TCTTAGATATAGGTTGTATAAAAGATAACTATTGTGCTGATATGACAAGAACTGTATTCTATAAAGAAATACCTGAAAAA
GGTAGAGAAATATTTGAAATAGTTCTTGAAGCTAATAAGAGAGCTGAAGCTATTGTAAAACCAGGTGTTAGATTCTGTGA
TATAGATGCTGCTGCTCGTGACTACATAACTGAAAAGGGATATGGACAGTACTTCACTCATAGAACTGGTCACTCTATAG
GACTTGAAGTTCATGATAAAGGAGATGTATCTTCTATAAATACAGATACTGTACAACCAGGAATGATATTCTCTATAGAG
CCAGGTATATATTTACCAGGTGAGTTCGGAGTTAGAATAGAAGATTTAGTACTTGTTACTGAAGATGGTTGTGAGATATT
AAACAAGCATGACAAAGAAATATGTGTAGTTGGTTAA

Upstream 100 bases:

>100_bases
TAACAAATTTTTTTTATATTTCTAGAAGAAAAGTATACTCTTTTTTGTTTAATAATGCTAAAATTGATTTGTATTGAATT
TTGATTAGGAGGAAATTATT

Downstream 100 bases:

>100_bases
TTCTAAAATCAATTTGATAAAATTAAAAAGCCATATAAAAATGTTTTAAACATTTTTATATGGCTTTAATTTCTCAATCT
ATTATTTATTTCAATCCATT

Product: peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MKAQRLNAVLEQMKKDDISQMLVSDPTSIFYLTGVLIHPGERLLALYLNLNGNNKLFINELFPVSEDLGVEMVWFNDTQN
PVEIITEHIDKNATMGVDKNWPARFLLNLIELGGGSKFVNSSYIIDTLRMCKDEEEKELMRIASKLNDKAMEQLKATVSG
ELTEKQLVGKLSKIYEDLGTDGFSFDPIIGFGPNGANPHGEPGNALVKPGDAIILDIGCIKDNYCADMTRTVFYKEIPEK
GREIFEIVLEANKRAEAIVKPGVRFCDIDAAARDYITEKGYGQYFTHRTGHSIGLEVHDKGDVSSINTDTVQPGMIFSIE
PGIYLPGEFGVRIEDLVLVTEDGCEILNKHDKEICVVG

Sequences:

>Translated_358_residues
MKAQRLNAVLEQMKKDDISQMLVSDPTSIFYLTGVLIHPGERLLALYLNLNGNNKLFINELFPVSEDLGVEMVWFNDTQN
PVEIITEHIDKNATMGVDKNWPARFLLNLIELGGGSKFVNSSYIIDTLRMCKDEEEKELMRIASKLNDKAMEQLKATVSG
ELTEKQLVGKLSKIYEDLGTDGFSFDPIIGFGPNGANPHGEPGNALVKPGDAIILDIGCIKDNYCADMTRTVFYKEIPEK
GREIFEIVLEANKRAEAIVKPGVRFCDIDAAARDYITEKGYGQYFTHRTGHSIGLEVHDKGDVSSINTDTVQPGMIFSIE
PGIYLPGEFGVRIEDLVLVTEDGCEILNKHDKEICVVG
>Mature_358_residues
MKAQRLNAVLEQMKKDDISQMLVSDPTSIFYLTGVLIHPGERLLALYLNLNGNNKLFINELFPVSEDLGVEMVWFNDTQN
PVEIITEHIDKNATMGVDKNWPARFLLNLIELGGGSKFVNSSYIIDTLRMCKDEEEKELMRIASKLNDKAMEQLKATVSG
ELTEKQLVGKLSKIYEDLGTDGFSFDPIIGFGPNGANPHGEPGNALVKPGDAIILDIGCIKDNYCADMTRTVFYKEIPEK
GREIFEIVLEANKRAEAIVKPGVRFCDIDAAARDYITEKGYGQYFTHRTGHSIGLEVHDKGDVSSINTDTVQPGMIFSIE
PGIYLPGEFGVRIEDLVLVTEDGCEILNKHDKEICVVG

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=258, Percent_Identity=31.0077519379845, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI149589008, Length=307, Percent_Identity=25.4071661237785, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI260593665, Length=307, Percent_Identity=25.4071661237785, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI264681563, Length=166, Percent_Identity=33.7349397590361, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI93141226, Length=172, Percent_Identity=32.5581395348837, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1788728, Length=238, Percent_Identity=40.3361344537815, Blast_Score=195, Evalue=3e-51,
Organism=Escherichia coli, GI1789275, Length=265, Percent_Identity=24.9056603773585, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786364, Length=247, Percent_Identity=27.1255060728745, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17508215, Length=365, Percent_Identity=26.027397260274, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17509539, Length=244, Percent_Identity=27.8688524590164, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321118, Length=295, Percent_Identity=26.1016949152542, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6320922, Length=242, Percent_Identity=23.5537190082645, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322999, Length=206, Percent_Identity=29.126213592233, Blast_Score=63, Evalue=8e-11,
Organism=Drosophila melanogaster, GI19920384, Length=285, Percent_Identity=24.5614035087719, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI21355531, Length=243, Percent_Identity=25.1028806584362, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 39823; Mature: 39823

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAQRLNAVLEQMKKDDISQMLVSDPTSIFYLTGVLIHPGERLLALYLNLNGNNKLFINE
CCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCEEEEEEEEECCCCEEEEEE
LFPVSEDLGVEMVWFNDTQNPVEIITEHIDKNATMGVDKNWPARFLLNLIELGGGSKFVN
CCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
SSYIIDTLRMCKDEEEKELMRIASKLNDKAMEQLKATVSGELTEKQLVGKLSKIYEDLGT
CHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
DGFSFDPIIGFGPNGANPHGEPGNALVKPGDAIILDIGCIKDNYCADMTRTVFYKEIPEK
CCCCCCCEEEECCCCCCCCCCCCCCEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHH
GREIFEIVLEANKRAEAIVKPGVRFCDIDAAARDYITEKGYGQYFTHRTGHSIGLEVHDK
HHHHHHHHHHCCCHHHHHHCCCCEEEECCHHHHHHHHCCCCCCHHCCCCCCEEEEEEECC
GDVSSINTDTVQPGMIFSIEPGIYLPGEFGVRIEDLVLVTEDGCEILNKHDKEICVVG
CCCCCCCCCCCCCCEEEEECCCEEECCCCCCEEEEEEEEECCCHHHHCCCCCEEEEEC
>Mature Secondary Structure
MKAQRLNAVLEQMKKDDISQMLVSDPTSIFYLTGVLIHPGERLLALYLNLNGNNKLFINE
CCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCEEEEEEEEECCCCEEEEEE
LFPVSEDLGVEMVWFNDTQNPVEIITEHIDKNATMGVDKNWPARFLLNLIELGGGSKFVN
CCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
SSYIIDTLRMCKDEEEKELMRIASKLNDKAMEQLKATVSGELTEKQLVGKLSKIYEDLGT
CHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
DGFSFDPIIGFGPNGANPHGEPGNALVKPGDAIILDIGCIKDNYCADMTRTVFYKEIPEK
CCCCCCCEEEECCCCCCCCCCCCCCEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHH
GREIFEIVLEANKRAEAIVKPGVRFCDIDAAARDYITEKGYGQYFTHRTGHSIGLEVHDK
HHHHHHHHHHCCCHHHHHHCCCCEEEECCHHHHHHHHCCCCCCHHCCCCCCEEEEEEECC
GDVSSINTDTVQPGMIFSIEPGIYLPGEFGVRIEDLVLVTEDGCEILNKHDKEICVVG
CCCCCCCCCCCCCCEEEEECCCEEECCCCCCEEEEEEEEECCCHHHHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA