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The map label for this gene is lldD [H]

Identifier: 126700002

GI number: 126700002

Start: 2756823

End: 2757845

Strand: Direct

Name: lldD [H]

Synonym: CD2387

Alternate gene names: 126700002

Gene position: 2756823-2757845 (Clockwise)

Preceding gene: 126699990

Following gene: 126700014

Centisome position: 64.26

GC content: 34.21

Gene sequence:

>1023_bases
ATGGATTACAATGACTTACTAAAATCAGCTAGAGAGAACTTTAATGGAACATGTAAAGTATGTAAAATTTGTAATGGATT
AGCTTGTGCTGGAGATGTTCCTGGTATGGGTGGTAAAGGAAGTGGTTCGTCTTTCATTGAAAATAGAAAAAGTCTAGAAA
AAATAAAGATAAATATGAGAGTCATACATAATGTTTCAAAGCCAGATACATCCATAGAATTATTTGGTAGAAAAATGAGT
TCTCCTATATTCGCTGCACCTGTATCAGGTACTATATTGAACATGGGTGGTAAAGTTTCCGAAAAAGAATACATAGAGCC
TGTTGTTAGAGGTTGTTCTAATTCTGGAATTTATGCTATGGTTGGCGATACTAATGTAGATACTTTTTTACTGGATAATT
TAGATGTATTGAAGGATAATAGGGGAAATGGAATTGTATTTATAAAGCCTTGGAATAATTCAAAGATAATAGATAAAATT
AGATTGTCTGAAGAAGCAGGTGCTTTTGCAGTTGGTGTAGACCTTGATGCTTGTGGACTTATTAATAATCAATTTCAAGA
AAATCCTTTTTCTCCTAAAACAATTGATGAGATTAGAGAATTGGTTGAATCCACTAGATTACCTTTTATTATAAAAGGAA
TTATGACTGTAGATGATGCTTTGATGGCTGTAGAGTCTGGTGCTAGTGCCATTATTGTTTCAAATCATGGTGGAAGAGTA
CTTGATTATACTCCTGGTACTTGTGAGGTACTTCCAGATATAGCTAAGTCTGTAAAGGGAAAGATAACAATACTTGTTGA
TGGTGGAGTTAGGACTGGTGTTGATGTAGTTAAGATGCTTGGATTGGGTGCTGATGCTGTTTTGATGGGAAGACCTTTTG
TTACTGCTTCTTTTGGCGGTGGTCTTGATGGTGTGGAGTTTTTTATAGAGAAGGTTAGGAATGAGTTATGTGAGACTATG
ATTTTGACTGGTTGTCAAAATGTTAAGGATATAGATGGTAGAGTTATATGGAATTTATTGTAA

Upstream 100 bases:

>100_bases
TCTAGTTTAGCTCATCATAATAACATCCCTATATTTACAATTAAGATATTTTCAATATAGTAATACTCAATTTTAATATT
ATAAAAAGGAGAGATTTTGT

Downstream 100 bases:

>100_bases
AATAGTTTTATAACATTTATATTTAAATAGTGTCTCATTTAAATTGAAAAATCATATTGAGACACTATTTAATATATTTT
TAGATTTTAATCCTATGAAA

Product: dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MDYNDLLKSARENFNGTCKVCKICNGLACAGDVPGMGGKGSGSSFIENRKSLEKIKINMRVIHNVSKPDTSIELFGRKMS
SPIFAAPVSGTILNMGGKVSEKEYIEPVVRGCSNSGIYAMVGDTNVDTFLLDNLDVLKDNRGNGIVFIKPWNNSKIIDKI
RLSEEAGAFAVGVDLDACGLINNQFQENPFSPKTIDEIRELVESTRLPFIIKGIMTVDDALMAVESGASAIIVSNHGGRV
LDYTPGTCEVLPDIAKSVKGKITILVDGGVRTGVDVVKMLGLGADAVLMGRPFVTASFGGGLDGVEFFIEKVRNELCETM
ILTGCQNVKDIDGRVIWNLL

Sequences:

>Translated_340_residues
MDYNDLLKSARENFNGTCKVCKICNGLACAGDVPGMGGKGSGSSFIENRKSLEKIKINMRVIHNVSKPDTSIELFGRKMS
SPIFAAPVSGTILNMGGKVSEKEYIEPVVRGCSNSGIYAMVGDTNVDTFLLDNLDVLKDNRGNGIVFIKPWNNSKIIDKI
RLSEEAGAFAVGVDLDACGLINNQFQENPFSPKTIDEIRELVESTRLPFIIKGIMTVDDALMAVESGASAIIVSNHGGRV
LDYTPGTCEVLPDIAKSVKGKITILVDGGVRTGVDVVKMLGLGADAVLMGRPFVTASFGGGLDGVEFFIEKVRNELCETM
ILTGCQNVKDIDGRVIWNLL
>Mature_340_residues
MDYNDLLKSARENFNGTCKVCKICNGLACAGDVPGMGGKGSGSSFIENRKSLEKIKINMRVIHNVSKPDTSIELFGRKMS
SPIFAAPVSGTILNMGGKVSEKEYIEPVVRGCSNSGIYAMVGDTNVDTFLLDNLDVLKDNRGNGIVFIKPWNNSKIIDKI
RLSEEAGAFAVGVDLDACGLINNQFQENPFSPKTIDEIRELVESTRLPFIIKGIMTVDDALMAVESGASAIIVSNHGGRV
LDYTPGTCEVLPDIAKSVKGKITILVDGGVRTGVDVVKMLGLGADAVLMGRPFVTASFGGGLDGVEFFIEKVRNELCETM
ILTGCQNVKDIDGRVIWNLL

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI11068137, Length=343, Percent_Identity=29.7376093294461, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI54234014, Length=329, Percent_Identity=29.7872340425532, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI7705393, Length=329, Percent_Identity=29.7872340425532, Blast_Score=125, Evalue=6e-29,
Organism=Escherichia coli, GI1790033, Length=156, Percent_Identity=42.3076923076923, Blast_Score=117, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI193208036, Length=137, Percent_Identity=38.6861313868613, Blast_Score=109, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6323587, Length=326, Percent_Identity=29.7546012269939, Blast_Score=112, Evalue=7e-26,
Organism=Drosophila melanogaster, GI78707188, Length=187, Percent_Identity=37.4331550802139, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI281363140, Length=187, Percent_Identity=37.4331550802139, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI78707190, Length=187, Percent_Identity=37.4331550802139, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 36547; Mature: 36547

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYNDLLKSARENFNGTCKVCKICNGLACAGDVPGMGGKGSGSSFIENRKSLEKIKINMR
CCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEH
VIHNVSKPDTSIELFGRKMSSPIFAAPVSGTILNMGGKVSEKEYIEPVVRGCSNSGIYAM
EEECCCCCCCHHHHHHHHHCCCEEEECCCCEEEECCCCCCHHHHHHHHHHCCCCCCEEEE
VGDTNVDTFLLDNLDVLKDNRGNGIVFIKPWNNSKIIDKIRLSEEAGAFAVGVDLDACGL
ECCCCCCEEEECCCHHHCCCCCCEEEEEEECCCCCHHHHEEECCCCCEEEEECCCCHHHH
INNQFQENPFSPKTIDEIRELVESTRLPFIIKGIMTVDDALMAVESGASAIIVSNHGGRV
HCCHHHCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCEEEEECCCCEE
LDYTPGTCEVLPDIAKSVKGKITILVDGGVRTGVDVVKMLGLGADAVLMGRPFVTASFGG
EEECCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEECCCEEEEECCC
GLDGVEFFIEKVRNELCETMILTGCQNVKDIDGRVIWNLL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MDYNDLLKSARENFNGTCKVCKICNGLACAGDVPGMGGKGSGSSFIENRKSLEKIKINMR
CCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEH
VIHNVSKPDTSIELFGRKMSSPIFAAPVSGTILNMGGKVSEKEYIEPVVRGCSNSGIYAM
EEECCCCCCCHHHHHHHHHCCCEEEECCCCEEEECCCCCCHHHHHHHHHHCCCCCCEEEE
VGDTNVDTFLLDNLDVLKDNRGNGIVFIKPWNNSKIIDKIRLSEEAGAFAVGVDLDACGL
ECCCCCCEEEECCCHHHCCCCCCEEEEEEECCCCCHHHHEEECCCCCEEEEECCCCHHHH
INNQFQENPFSPKTIDEIRELVESTRLPFIIKGIMTVDDALMAVESGASAIIVSNHGGRV
HCCHHHCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCEEEEECCCCEE
LDYTPGTCEVLPDIAKSVKGKITILVDGGVRTGVDVVKMLGLGADAVLMGRPFVTASFGG
EEECCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEECCCEEEEECCC
GLDGVEFFIEKVRNELCETMILTGCQNVKDIDGRVIWNLL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA