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The map label for this gene is xylR [H]

Identifier: 126699810

GI number: 126699810

Start: 2541031

End: 2542245

Strand: Direct

Name: xylR [H]

Synonym: CD2194

Alternate gene names: 126699810

Gene position: 2541031-2542245 (Clockwise)

Preceding gene: 126699796

Following gene: 126699811

Centisome position: 59.23

GC content: 27.0

Gene sequence:

>1215_bases
ATGATGAGTAACAAACAAGGTTCTAACATCAAAGATGTAAAAATTAAAAATAAGTTAATAATATTGAAATTACTTTCTAC
AAATACACCTATGTCCAGAGTTGATTTAGCTAAGTCTACAGGACTTACTAAAATGACTTTATCAAATCTAGTTACTGAAC
TTATTAATGAAAATATGATTAGGGAAATAGAGTCATCAACTTTAAATGCACATTCATCAGGTCGTAAACCCATTTTATTA
GATATTTCTAATATATCGCCTTGTATTTGTGGAATCCTAATAAGAAGAAATATATGTAAGGTAATTATTTCAGATTTAAA
AGGTAATATTGTAAAACAACTTTCTGAAACTTACCCTAAATGTCTATCAAATGATGTTTTAAAAGATATAATAAAAAGAA
TGTTTACTAAAATAATGAAAATCAACAAGAGAGATATAATTGGAATTGGTATTTCTTCAATAGGTCCAGTAGATGATATA
AATGGTACCATACTAAATCCCCCAGATTTTGGAAATGTATCAAACCTAAATATAGTAGATTTTATAAAAGAAATGTCTGA
TTTGCCAATATTTTTGATAAATGATGCTAATTCGGGTGCATTAGCAGAAAAAATGTATGGTTTAGGTAAAAATATATCAA
ATTATATATACCTACACATAATGAATGGTATTGGAGCTGGTCTAGTTCTAGAAAATAAACTTCATACTGGCAACCTAGGA
CAAAGTGGAGAAATAGGACATACATCAATTAATTTTAGTGGACCATTGTGCAGTTGTGGTAACAATGGATGTTTAGATTA
TTATACAAGTGTCAGTAATCTAATTAAAAGAATTGAATCATTGAGCCATATTTATCCTAACTCCCCATTAATTAACTGTA
AAGATTTTTCTTTAGTCAAGTTAATAGATGAGGCAAATAATAAAGATAGTCTTGCCATGTTTTTGCTTGATGAATTTTGT
ACATACGTATCATATGCATTAGTTAATACACTTACATTGATTGATTGTAGTTCTATAATAATAGGCTATGACTTTAATAT
ACCTGGTACATTTATAGAAAATACATTATTAAAAAAATTGACTGCTTCAGCAAGTTTTTCTAAATATAAAAAAATAAGTG
TAAGGCATTCAAATTTTGGAGCAAATGCACCATTAATTGGCTCTATAGCCATTGTAAGTTATAATTTTTTTAATGGTAGT
ATAAATTTTTATTAA

Upstream 100 bases:

>100_bases
TCTAATTAATGATATTTTCAAGTAAAAAAATGTTACTCTATTATAAGGTGATAGTATACTTGAAAATAAATAAAACACTT
AACTTTATTTAAGGAGATTT

Downstream 100 bases:

>100_bases
ATATGTAAAATATTTAAACACTTTTATTGAATATTTTTCCATTTAATATTATTATATTTTATAAGAGCATTTAAAATTTG
GAGGTATAAAAATGATTTCA

Product: regulator of a specific sugar metabolism

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MMSNKQGSNIKDVKIKNKLIILKLLSTNTPMSRVDLAKSTGLTKMTLSNLVTELINENMIREIESSTLNAHSSGRKPILL
DISNISPCICGILIRRNICKVIISDLKGNIVKQLSETYPKCLSNDVLKDIIKRMFTKIMKINKRDIIGIGISSIGPVDDI
NGTILNPPDFGNVSNLNIVDFIKEMSDLPIFLINDANSGALAEKMYGLGKNISNYIYLHIMNGIGAGLVLENKLHTGNLG
QSGEIGHTSINFSGPLCSCGNNGCLDYYTSVSNLIKRIESLSHIYPNSPLINCKDFSLVKLIDEANNKDSLAMFLLDEFC
TYVSYALVNTLTLIDCSSIIIGYDFNIPGTFIENTLLKKLTASASFSKYKKISVRHSNFGANAPLIGSIAIVSYNFFNGS
INFY

Sequences:

>Translated_404_residues
MMSNKQGSNIKDVKIKNKLIILKLLSTNTPMSRVDLAKSTGLTKMTLSNLVTELINENMIREIESSTLNAHSSGRKPILL
DISNISPCICGILIRRNICKVIISDLKGNIVKQLSETYPKCLSNDVLKDIIKRMFTKIMKINKRDIIGIGISSIGPVDDI
NGTILNPPDFGNVSNLNIVDFIKEMSDLPIFLINDANSGALAEKMYGLGKNISNYIYLHIMNGIGAGLVLENKLHTGNLG
QSGEIGHTSINFSGPLCSCGNNGCLDYYTSVSNLIKRIESLSHIYPNSPLINCKDFSLVKLIDEANNKDSLAMFLLDEFC
TYVSYALVNTLTLIDCSSIIIGYDFNIPGTFIENTLLKKLTASASFSKYKKISVRHSNFGANAPLIGSIAIVSYNFFNGS
INFY
>Mature_404_residues
MMSNKQGSNIKDVKIKNKLIILKLLSTNTPMSRVDLAKSTGLTKMTLSNLVTELINENMIREIESSTLNAHSSGRKPILL
DISNISPCICGILIRRNICKVIISDLKGNIVKQLSETYPKCLSNDVLKDIIKRMFTKIMKINKRDIIGIGISSIGPVDDI
NGTILNPPDFGNVSNLNIVDFIKEMSDLPIFLINDANSGALAEKMYGLGKNISNYIYLHIMNGIGAGLVLENKLHTGNLG
QSGEIGHTSINFSGPLCSCGNNGCLDYYTSVSNLIKRIESLSHIYPNSPLINCKDFSLVKLIDEANNKDSLAMFLLDEFC
TYVSYALVNTLTLIDCSSIIIGYDFNIPGTFIENTLLKKLTASASFSKYKKISVRHSNFGANAPLIGSIAIVSYNFFNGS
INFY

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=255, Percent_Identity=29.4117647058824, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI298566315, Length=255, Percent_Identity=29.4117647058824, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI190014632, Length=255, Percent_Identity=29.4117647058824, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI4885285, Length=257, Percent_Identity=29.9610894941634, Blast_Score=93, Evalue=4e-19,
Organism=Escherichia coli, GI1787878, Length=408, Percent_Identity=22.3039215686275, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1786891, Length=412, Percent_Identity=23.7864077669903, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI87082127, Length=380, Percent_Identity=22.6315789473684, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI87082230, Length=235, Percent_Identity=23.4042553191489, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 44376; Mature: 44376

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSNKQGSNIKDVKIKNKLIILKLLSTNTPMSRVDLAKSTGLTKMTLSNLVTELINENMI
CCCCCCCCCCCEEEECCEEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
REIESSTLNAHSSGRKPILLDISNISPCICGILIRRNICKVIISDLKGNIVKQLSETYPK
HHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CLSNDVLKDIIKRMFTKIMKINKRDIIGIGISSIGPVDDINGTILNPPDFGNVSNLNIVD
HHCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCEECCCCCCCCCCCHHHH
FIKEMSDLPIFLINDANSGALAEKMYGLGKNISNYIYLHIMNGIGAGLVLENKLHTGNLG
HHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEECCCCCCCCC
QSGEIGHTSINFSGPLCSCGNNGCLDYYTSVSNLIKRIESLSHIYPNSPLINCKDFSLVK
CCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHH
LIDEANNKDSLAMFLLDEFCTYVSYALVNTLTLIDCSSIIIGYDFNIPGTFIENTLLKKL
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCCHHHHHHHHHHHH
TASASFSKYKKISVRHSNFGANAPLIGSIAIVSYNFFNGSINFY
HHHCCHHHHHEEEEEECCCCCCCCCEEEEEEEEEEEECCCEECC
>Mature Secondary Structure
MMSNKQGSNIKDVKIKNKLIILKLLSTNTPMSRVDLAKSTGLTKMTLSNLVTELINENMI
CCCCCCCCCCCEEEECCEEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
REIESSTLNAHSSGRKPILLDISNISPCICGILIRRNICKVIISDLKGNIVKQLSETYPK
HHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CLSNDVLKDIIKRMFTKIMKINKRDIIGIGISSIGPVDDINGTILNPPDFGNVSNLNIVD
HHCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCEECCCCCCCCCCCHHHH
FIKEMSDLPIFLINDANSGALAEKMYGLGKNISNYIYLHIMNGIGAGLVLENKLHTGNLG
HHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEECCCCCCCCC
QSGEIGHTSINFSGPLCSCGNNGCLDYYTSVSNLIKRIESLSHIYPNSPLINCKDFSLVK
CCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHH
LIDEANNKDSLAMFLLDEFCTYVSYALVNTLTLIDCSSIIIGYDFNIPGTFIENTLLKKL
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCCHHHHHHHHHHHH
TASASFSKYKKISVRHSNFGANAPLIGSIAIVSYNFFNGSINFY
HHHCCHHHHHEEEEEECCCCCCCCCEEEEEEEEEEEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]