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The map label for this gene is crp [C]

Identifier: 126699786

GI number: 126699786

Start: 2510369

End: 2511097

Strand: Direct

Name: crp [C]

Synonym: CD2170

Alternate gene names: 126699786

Gene position: 2510369-2511097 (Clockwise)

Preceding gene: 126699780

Following gene: 126699796

Centisome position: 58.51

GC content: 29.63

Gene sequence:

>729_bases
ATGAAAACAAATTATCGGTTGCATATGCAACAAGGAAGTGATTATTTGAAAAAATTTTTAGAAAAGCATATAGACCTACT
TAAAAAAATTCCTCTATTTGAAGGAATTAAAAGTGATGAACTTGAAGAAATGTTGGAATGTTTAGGTGTTGTAGATAAAA
CTTACCCAAAAGATAGTATAATATTCTCTGTTGGAAGTGAAGTTACTTCTATTGGAATTATGCTTAAAGGAAGTGCTCAT
ATAATAAAGGAAGATATCGAAGGGAATAGGAATATTGTAGCTGAACTCTTGCCTGGAGATTTATTTGGAGAGGTATTCGC
ATGTACTAGACTACATAAAAGTAATGTTACAGTAACCACAACATCTTCTTGCGAAGTTTTATTTATAAAGTTTAAAAGTG
TAACTGGTATTTGTTCATCTACATGTGTATTTCATAATAGGCTTGTTGAAAATATGCTACAATTAATAGCTGAAAAAAAC
ATTTTACTTCACAATAAAATAGAATTACTTTCTCGTAAAACAACTCGCGAGAAATTGCTTATGTATTTTTCAAAACAGAT
AGAACAAACAGGTAGCCACCAGTTTACAATTCCCTTTTCAAGAAATGAAATGGCTGATTTTTTATGTGTTGACAGAAGTT
CTATGTCAAGAGAGCTTGGCAAGATGCGAGATGAAGGCTTGTTATCTTTTAACAAAAATAAATTTGAAATCTTTTATTTT
AAAAAATAA

Upstream 100 bases:

>100_bases
TTTCTTATATATTTATTTTTAATACCTATATTTCTTTATTTCAAATTTCTTGTAGTAGGATTTTTATATCCCCTTGCTTT
TATAAACTTAGTATAGTACA

Downstream 100 bases:

>100_bases
AATAGATATTTAAACATATTTATTTCAATATATACTATATTAGTTGATTCAAATTATAAATATCATATTTGAATCTTAAA
TTTATATTTTTACTTAAAAA

Product: cNMP-binding regulatory protein

Products: NA

Alternate protein names: Transcriptional Regulatory Protein; Transcriptional Regulator; Transcriptional Regulator Crp Family; Crp/Fnr Family Transcriptional Regulator; CAMP-Regulatory Protein; Regulatory Protein; CRP/FNR Family Transcriptional Regulator; Crp Family Transcriptional Regulator

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MKTNYRLHMQQGSDYLKKFLEKHIDLLKKIPLFEGIKSDELEEMLECLGVVDKTYPKDSIIFSVGSEVTSIGIMLKGSAH
IIKEDIEGNRNIVAELLPGDLFGEVFACTRLHKSNVTVTTTSSCEVLFIKFKSVTGICSSTCVFHNRLVENMLQLIAEKN
ILLHNKIELLSRKTTREKLLMYFSKQIEQTGSHQFTIPFSRNEMADFLCVDRSSMSRELGKMRDEGLLSFNKNKFEIFYF
KK

Sequences:

>Translated_242_residues
MKTNYRLHMQQGSDYLKKFLEKHIDLLKKIPLFEGIKSDELEEMLECLGVVDKTYPKDSIIFSVGSEVTSIGIMLKGSAH
IIKEDIEGNRNIVAELLPGDLFGEVFACTRLHKSNVTVTTTSSCEVLFIKFKSVTGICSSTCVFHNRLVENMLQLIAEKN
ILLHNKIELLSRKTTREKLLMYFSKQIEQTGSHQFTIPFSRNEMADFLCVDRSSMSRELGKMRDEGLLSFNKNKFEIFYF
KK
>Mature_242_residues
MKTNYRLHMQQGSDYLKKFLEKHIDLLKKIPLFEGIKSDELEEMLECLGVVDKTYPKDSIIFSVGSEVTSIGIMLKGSAH
IIKEDIEGNRNIVAELLPGDLFGEVFACTRLHKSNVTVTTTSSCEVLFIKFKSVTGICSSTCVFHNRLVENMLQLIAEKN
ILLHNKIELLSRKTTREKLLMYFSKQIEQTGSHQFTIPFSRNEMADFLCVDRSSMSRELGKMRDEGLLSFNKNKFEIFYF
KK

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 27810; Mature: 27810

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTNYRLHMQQGSDYLKKFLEKHIDLLKKIPLFEGIKSDELEEMLECLGVVDKTYPKDSI
CCCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHCCCCCCCE
IFSVGSEVTSIGIMLKGSAHIIKEDIEGNRNIVAELLPGDLFGEVFACTRLHKSNVTVTT
EEECCCCHHEEEEEEECCHHHHHHHCCCCCCEEEHHCCCHHHHHHHHHHHHHCCCEEEEE
TSSCEVLFIKFKSVTGICSSTCVFHNRLVENMLQLIAEKNILLHNKIELLSRKTTREKLL
CCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
MYFSKQIEQTGSHQFTIPFSRNEMADFLCVDRSSMSRELGKMRDEGLLSFNKNKFEIFYF
HHHHHHHHHCCCEEEEEECCCCCHHHHHEECHHHHHHHHHHHHHCCCEEECCCEEEEEEE
KK
EC
>Mature Secondary Structure
MKTNYRLHMQQGSDYLKKFLEKHIDLLKKIPLFEGIKSDELEEMLECLGVVDKTYPKDSI
CCCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHCCCCCCCE
IFSVGSEVTSIGIMLKGSAHIIKEDIEGNRNIVAELLPGDLFGEVFACTRLHKSNVTVTT
EEECCCCHHEEEEEEECCHHHHHHHCCCCCCEEEHHCCCHHHHHHHHHHHHHCCCEEEEE
TSSCEVLFIKFKSVTGICSSTCVFHNRLVENMLQLIAEKNILLHNKIELLSRKTTREKLL
CCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
MYFSKQIEQTGSHQFTIPFSRNEMADFLCVDRSSMSRELGKMRDEGLLSFNKNKFEIFYF
HHHHHHHHHCCCEEEEEECCCCCHHHHHEECHHHHHHHHHHHHHCCCEEECCCEEEEEEE
KK
EC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA