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The map label for this gene is 126699771

Identifier: 126699771

GI number: 126699771

Start: 2493479

End: 2494570

Strand: Direct

Name: 126699771

Synonym: CD2155

Alternate gene names: NA

Gene position: 2493479-2494570 (Clockwise)

Preceding gene: 126699770

Following gene: 126699772

Centisome position: 58.12

GC content: 30.68

Gene sequence:

>1092_bases
TTGAATATGACTAAAAATAAGATTAAATACTTTATAGATAAACTTTACAGCATTAATTCATTAAGTTTTGATGAACTACT
ATATTTAATAGAAAATATCGACAATGAGGAATATAACTTCGAACAAAATTTAAGAAACTATCTTTATAAACAAGCTAGCG
ACATGAGAAATAAACATTATGGAAATAGAGTCTACTTGAGAGGACTTATAGAGCTTACAAACTATTGTAAAAATAATTGC
TACTATTGTGGAATACAATCTTCTAATAAAAATATCATAAGATACAGGCTTTCACTTGATGAAATACTTGAATGTTGTGA
TATAGGTTATAAAATAGGATACAGAACATTCGTTTTGCAAGGTGGTGAAGATGCATATTTTACTGATGATAAAATATGTG
AAATTGTTTCAAGTATAAAAAATAAATATGAGGATTGTGCCATAACTCTATCACTAGGAGAAAAGAGTTATGATTCGTAT
AAAAAATACTTTTTATGTGGTGCAGATAGATATCTTTTAAGACATGAAACTGCTACAGACAGTCATTATAAAAAATTACA
TCCGCCAAACATTGAGCTTAGAACTAGAAAAGAATGCCTAAAAAACCTTAAAGAAATTGGTTATCAGGTAGGTGCTGGAT
TTATGGTTGAATCACCATTTCAGAACAACGAAGACCTTGTTCGTGATTTATTATACCTAAAAGAGTTAAATCCTCATATG
GTTGGAATAGGACCTTTCATTCCACACCATGATACAATTTTTAAGGATTATAAACATGGAGATTTAGAGAAGACATTACT
TATGCTTTCAATTACAAGACTTCTACTTCCAAAAGTTTTATTACCCGCTACAACAGCCTTGGCATCTATAAACCCTAGTG
GTAGAAATGCAGGTCTTTTAGCTGGTTGCAATGTAATTATGCCAAACCTTTCTCCTCAAGAATTTAGAAAACAATATTCT
CTTTACGATAACAAAGCCTTTACTGGTCAAGAAGCTTGTGAATATCACCAAAGTTTAGAAGAAAACATCAAGTCATTAGG
ACTTGAAGTTGACTATTCTCGCGGTGATAATATTGAATGGAGGCGTTTGTAA

Upstream 100 bases:

>100_bases
TAAACTATGGTGTCTTAATAGCATATGTAAAAGGTATTTTGGAAAGATCACTTGAACTTTTCAATTATTAAAAATTTAAC
TATACTTAATAATTACATAT

Downstream 100 bases:

>100_bases
ATGTTCATAAACCATGAACTTATTAATTCTTTATTAGAAGATGCAAAAAATTCAACTTCTGATGATATTGAAAAGGTACT
TGATAAGGCTGATAGAAGGG

Product: biotin synthase

Products: biotin

Alternate protein names: Radical SAM Domain Protein; Thiamine Biosynthesis Protein ThiH; Radical SAM Domain-Containing Protein; Iron-Only Hydrogenase Maturation Protein HydE; Biotin Synthetase; ThiH/BioB Family Protein; Fe-Hydrogenase Assembly Protein Radical Protein; Fe-Hydrogenase Assembly Protein; Thiazole Biosynthesis Protein ThiH; Thiamine Biosynthesis ThiH; Iron-Only Hydrogenase Maturation Protein; ThiH Protein; Radical SAM; Biotin Biosynthesis-Related Protein; Biotin Synthase And Related S; Biotin Synthase Family

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MNMTKNKIKYFIDKLYSINSLSFDELLYLIENIDNEEYNFEQNLRNYLYKQASDMRNKHYGNRVYLRGLIELTNYCKNNC
YYCGIQSSNKNIIRYRLSLDEILECCDIGYKIGYRTFVLQGGEDAYFTDDKICEIVSSIKNKYEDCAITLSLGEKSYDSY
KKYFLCGADRYLLRHETATDSHYKKLHPPNIELRTRKECLKNLKEIGYQVGAGFMVESPFQNNEDLVRDLLYLKELNPHM
VGIGPFIPHHDTIFKDYKHGDLEKTLLMLSITRLLLPKVLLPATTALASINPSGRNAGLLAGCNVIMPNLSPQEFRKQYS
LYDNKAFTGQEACEYHQSLEENIKSLGLEVDYSRGDNIEWRRL

Sequences:

>Translated_363_residues
MNMTKNKIKYFIDKLYSINSLSFDELLYLIENIDNEEYNFEQNLRNYLYKQASDMRNKHYGNRVYLRGLIELTNYCKNNC
YYCGIQSSNKNIIRYRLSLDEILECCDIGYKIGYRTFVLQGGEDAYFTDDKICEIVSSIKNKYEDCAITLSLGEKSYDSY
KKYFLCGADRYLLRHETATDSHYKKLHPPNIELRTRKECLKNLKEIGYQVGAGFMVESPFQNNEDLVRDLLYLKELNPHM
VGIGPFIPHHDTIFKDYKHGDLEKTLLMLSITRLLLPKVLLPATTALASINPSGRNAGLLAGCNVIMPNLSPQEFRKQYS
LYDNKAFTGQEACEYHQSLEENIKSLGLEVDYSRGDNIEWRRL
>Mature_363_residues
MNMTKNKIKYFIDKLYSINSLSFDELLYLIENIDNEEYNFEQNLRNYLYKQASDMRNKHYGNRVYLRGLIELTNYCKNNC
YYCGIQSSNKNIIRYRLSLDEILECCDIGYKIGYRTFVLQGGEDAYFTDDKICEIVSSIKNKYEDCAITLSLGEKSYDSY
KKYFLCGADRYLLRHETATDSHYKKLHPPNIELRTRKECLKNLKEIGYQVGAGFMVESPFQNNEDLVRDLLYLKELNPHM
VGIGPFIPHHDTIFKDYKHGDLEKTLLMLSITRLLLPKVLLPATTALASINPSGRNAGLLAGCNVIMPNLSPQEFRKQYS
LYDNKAFTGQEACEYHQSLEENIKSLGLEVDYSRGDNIEWRRL

Specific function: Unknown

COG id: COG0502

COG function: function code H; Biotin synthase and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.8.1.6

Molecular weight: Translated: 42267; Mature: 42267

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMTKNKIKYFIDKLYSINSLSFDELLYLIENIDNEEYNFEQNLRNYLYKQASDMRNKHY
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GNRVYLRGLIELTNYCKNNCYYCGIQSSNKNIIRYRLSLDEILECCDIGYKIGYRTFVLQ
CCCHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECHHHHHHHHHCCHHCCCEEEEEE
GGEDAYFTDDKICEIVSSIKNKYEDCAITLSLGEKSYDSYKKYFLCGADRYLLRHETATD
CCCCCCCCHHHHHHHHHHHHHCHHCEEEEEECCCCCHHHHHHEEEECCCHHHHEECCCCC
SHYKKLHPPNIELRTRKECLKNLKEIGYQVGAGFMVESPFQNNEDLVRDLLYLKELNPHM
CHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHCCCCE
VGIGPFIPHHDTIFKDYKHGDLEKTLLMLSITRLLLPKVLLPATTALASINPSGRNAGLL
EEECCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
AGCNVIMPNLSPQEFRKQYSLYDNKAFTGQEACEYHQSLEENIKSLGLEVDYSRGDNIEW
ECCEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEE
RRL
ECC
>Mature Secondary Structure
MNMTKNKIKYFIDKLYSINSLSFDELLYLIENIDNEEYNFEQNLRNYLYKQASDMRNKHY
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GNRVYLRGLIELTNYCKNNCYYCGIQSSNKNIIRYRLSLDEILECCDIGYKIGYRTFVLQ
CCCHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECHHHHHHHHHCCHHCCCEEEEEE
GGEDAYFTDDKICEIVSSIKNKYEDCAITLSLGEKSYDSYKKYFLCGADRYLLRHETATD
CCCCCCCCHHHHHHHHHHHHHCHHCEEEEEECCCCCHHHHHHEEEECCCHHHHEECCCCC
SHYKKLHPPNIELRTRKECLKNLKEIGYQVGAGFMVESPFQNNEDLVRDLLYLKELNPHM
CHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHCCCCE
VGIGPFIPHHDTIFKDYKHGDLEKTLLMLSITRLLLPKVLLPATTALASINPSGRNAGLL
EEECCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
AGCNVIMPNLSPQEFRKQYSLYDNKAFTGQEACEYHQSLEENIKSLGLEVDYSRGDNIEW
ECCEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEE
RRL
ECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dethiobiotin; sulfur

Specific reaction: dethiobiotin + sulfur = biotin

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA