Click here to switch to the map view.

The map label for this gene is der [H]

Identifier: 126699770

GI number: 126699770

Start: 2492241

End: 2493449

Strand: Direct

Name: der [H]

Synonym: CD2154

Alternate gene names: 126699770

Gene position: 2492241-2493449 (Clockwise)

Preceding gene: 126699769

Following gene: 126699771

Centisome position: 58.09

GC content: 30.27

Gene sequence:

>1209_bases
ATGAGTCTAAATTCTACTCCACAATCGGTAAGAGTACATATAGGTCTCTTTGGTAAAAGAAATGCAGGTAAATCTAGCAT
AATAAATGCTATAACAAATCAAAGTGCTGCAATAGTCTCAGATATTGCTGGAACTACTACAGACCCAGTATTTAGACCAA
TGGAAATCCTTCCTATAGGACCTTGTGTTCTTATAGATACTGCTGGTCTTGATGATGTTGGTGAACTTGGTGAACTTAGA
ATAGGTAAATCACTAGATGTTTTAGAAAAGACAGATATAGCTTTACTAGTAGTGGATTGCCAAATTGGTATATCACAAGA
AGATTTGTCACTAATTGAAAAATTTAATGATAAGAATATCCCTCATATTCTAATTCTTAACAAAATTGATACTATTAAGA
ATCAATCAGAAATTTTAAACTTAACTAAAAATAAAGTTAAATGTCCAGTTGTTTCTGTCTCATCAACAGATAAAATTGGA
ATTGAAAATTTAAAAAATGAAATAATAAAAGTTTTGCCTAAGGATAGCACTGAGTTCAAATTGGTATCAGATTTAATTGA
ACCAAATGATTTAGTTGTTTTAGTTGTTCCAATAGATAAAGCAGCTCCAAAAGGTAGACTTATACTTCCTCAACAGCAAG
TTATAAGAGATATTTTGGATAATGGTGCAATTTCTATAGTTACAAAAGAAGATAGTTTAAAAGAAACTCTATCTAATTTA
GGCAAAAAACCAAAACTTGTTATTACTGACTCTCAAGTATTTCCACAAGTAGATAAAGATACACCAAAAGATATTCCTCT
TACATCTTTTTCTATATTGTTTGCTAGACAAAAGGGAGACCTTAAAGAATTGATTAATGGAGCTTATGCTTTAGAAAATT
TAAAAGATGGTGATAAAATCTTGATGGCCGAAGGATGTACCCATCATAGACAAACTGATGATATTGGAACAGTAAAAATT
CCTAATATGATTAGAAAGAAAACTGGCAAAAACATTACTTTTGAATTTAGTTCTGGAGTATCCTTCACTGAAGATATAAA
TAAATATGCCCTTGTAGTTCACTGTGGAGCTTGTATGATGAATAGAGCTGGAATGTTATCTAGAATAGAAAAGGCAAAAT
CTTTCAATGTACCTATTGTAAACTATGGTGTCTTAATAGCATATGTAAAAGGTATTTTGGAAAGATCACTTGAACTTTTC
AATTATTAA

Upstream 100 bases:

>100_bases
TGGATACTATTAATAGTTTGACTGGTAAATTGGGCAACATACCTCATGTATCTGTAAAAACTAGTATATCAAAAAAAGAA
GTTTAAGGTGGTGAGTACAA

Downstream 100 bases:

>100_bases
AAATTTAACTATACTTAATAATTACATATTTGAATATGACTAAAAATAAGATTAAATACTTTATAGATAAACTTTACAGC
ATTAATTCATTAAGTTTTGA

Product: ATP/GTP-binding protein

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MSLNSTPQSVRVHIGLFGKRNAGKSSIINAITNQSAAIVSDIAGTTTDPVFRPMEILPIGPCVLIDTAGLDDVGELGELR
IGKSLDVLEKTDIALLVVDCQIGISQEDLSLIEKFNDKNIPHILILNKIDTIKNQSEILNLTKNKVKCPVVSVSSTDKIG
IENLKNEIIKVLPKDSTEFKLVSDLIEPNDLVVLVVPIDKAAPKGRLILPQQQVIRDILDNGAISIVTKEDSLKETLSNL
GKKPKLVITDSQVFPQVDKDTPKDIPLTSFSILFARQKGDLKELINGAYALENLKDGDKILMAEGCTHHRQTDDIGTVKI
PNMIRKKTGKNITFEFSSGVSFTEDINKYALVVHCGACMMNRAGMLSRIEKAKSFNVPIVNYGVLIAYVKGILERSLELF
NY

Sequences:

>Translated_402_residues
MSLNSTPQSVRVHIGLFGKRNAGKSSIINAITNQSAAIVSDIAGTTTDPVFRPMEILPIGPCVLIDTAGLDDVGELGELR
IGKSLDVLEKTDIALLVVDCQIGISQEDLSLIEKFNDKNIPHILILNKIDTIKNQSEILNLTKNKVKCPVVSVSSTDKIG
IENLKNEIIKVLPKDSTEFKLVSDLIEPNDLVVLVVPIDKAAPKGRLILPQQQVIRDILDNGAISIVTKEDSLKETLSNL
GKKPKLVITDSQVFPQVDKDTPKDIPLTSFSILFARQKGDLKELINGAYALENLKDGDKILMAEGCTHHRQTDDIGTVKI
PNMIRKKTGKNITFEFSSGVSFTEDINKYALVVHCGACMMNRAGMLSRIEKAKSFNVPIVNYGVLIAYVKGILERSLELF
NY
>Mature_401_residues
SLNSTPQSVRVHIGLFGKRNAGKSSIINAITNQSAAIVSDIAGTTTDPVFRPMEILPIGPCVLIDTAGLDDVGELGELRI
GKSLDVLEKTDIALLVVDCQIGISQEDLSLIEKFNDKNIPHILILNKIDTIKNQSEILNLTKNKVKCPVVSVSSTDKIGI
ENLKNEIIKVLPKDSTEFKLVSDLIEPNDLVVLVVPIDKAAPKGRLILPQQQVIRDILDNGAISIVTKEDSLKETLSNLG
KKPKLVITDSQVFPQVDKDTPKDIPLTSFSILFARQKGDLKELINGAYALENLKDGDKILMAEGCTHHRQTDDIGTVKIP
NMIRKKTGKNITFEFSSGVSFTEDINKYALVVHCGACMMNRAGMLSRIEKAKSFNVPIVNYGVLIAYVKGILERSLELFN
Y

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=133, Percent_Identity=32.3308270676692, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 44083; Mature: 43952

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNSTPQSVRVHIGLFGKRNAGKSSIINAITNQSAAIVSDIAGTTTDPVFRPMEILPIG
CCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEEEECC
PCVLIDTAGLDDVGELGELRIGKSLDVLEKTDIALLVVDCQIGISQEDLSLIEKFNDKNI
CEEEEECCCCCCCHHHCCEECCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHCCCCCC
PHILILNKIDTIKNQSEILNLTKNKVKCPVVSVSSTDKIGIENLKNEIIKVLPKDSTEFK
CEEEEEECHHHHCCHHHHHHHHCCCEECEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHH
LVSDLIEPNDLVVLVVPIDKAAPKGRLILPQQQVIRDILDNGAISIVTKEDSLKETLSNL
HHHHHCCCCCEEEEEEECCCCCCCCCEECCHHHHHHHHHCCCCEEEEECCHHHHHHHHHC
GKKPKLVITDSQVFPQVDKDTPKDIPLTSFSILFARQKGDLKELINGAYALENLKDGDKI
CCCCEEEEECCHHCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCEE
LMAEGCTHHRQTDDIGTVKIPNMIRKKTGKNITFEFSSGVSFTEDINKYALVVHCGACMM
EEECCCCCCCCCCCCCEEECCHHHHHHCCCEEEEEECCCCCHHHHHCCEEEEEEHHHHHH
NRAGMLSRIEKAKSFNVPIVNYGVLIAYVKGILERSLELFNY
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLNSTPQSVRVHIGLFGKRNAGKSSIINAITNQSAAIVSDIAGTTTDPVFRPMEILPIG
CCCCCCCEEEEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEEEECC
PCVLIDTAGLDDVGELGELRIGKSLDVLEKTDIALLVVDCQIGISQEDLSLIEKFNDKNI
CEEEEECCCCCCCHHHCCEECCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHCCCCCC
PHILILNKIDTIKNQSEILNLTKNKVKCPVVSVSSTDKIGIENLKNEIIKVLPKDSTEFK
CEEEEEECHHHHCCHHHHHHHHCCCEECEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHH
LVSDLIEPNDLVVLVVPIDKAAPKGRLILPQQQVIRDILDNGAISIVTKEDSLKETLSNL
HHHHHCCCCCEEEEEEECCCCCCCCCEECCHHHHHHHHHCCCCEEEEECCHHHHHHHHHC
GKKPKLVITDSQVFPQVDKDTPKDIPLTSFSILFARQKGDLKELINGAYALENLKDGDKI
CCCCEEEEECCHHCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCEE
LMAEGCTHHRQTDDIGTVKIPNMIRKKTGKNITFEFSSGVSFTEDINKYALVVHCGACMM
EEECCCCCCCCCCCCCEEECCHHHHHHCCCEEEEEECCCCCHHHHHCCEEEEEEHHHHHH
NRAGMLSRIEKAKSFNVPIVNYGVLIAYVKGILERSLELFNY
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA