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The map label for this gene is dspA [H]

Identifier: 126699569

GI number: 126699569

Start: 2259619

End: 2260650

Strand: Direct

Name: dspA [H]

Synonym: CD1960

Alternate gene names: 126699569

Gene position: 2259619-2260650 (Clockwise)

Preceding gene: 126699568

Following gene: 126699570

Centisome position: 52.67

GC content: 24.71

Gene sequence:

>1032_bases
ATGAATTTTAAAAAATTTTCTTTTAGTTCTATTTATTTAATAATTGCTGTTGGTATAATTTTTACAGCTATTTTATTTAG
TATCTCAATTTATCTAATAACTGGTGATTTAAAACTAATTGCTCTATTATTAATATATACAATGGTACTTTGTGGATTTA
TAGCATTAATAATATTTTTACTTCATAAAAAAATAGTTATATTTTGTTCTAAAATATGTCACACTTTAGATAGTATGATG
AATAGTGAAGATAATATTGAAATTGAATTAGAAGAAGAAACTATTTTATCACGTATCAATCACAGATTAATTAGAATGTA
TGAAGTTATTCAAGAAAATCGCAATAGTATTGCTATAGAGAAAGCTGATTTACAAGAACTAGTTTCTGATATATCTCATC
AAATTAAAACTCCTATTGCAAATTTAAAAATGATTAATACTACTCTACTAAATCAAACATTTAAAACAGAAATTCAAAAG
GATTTTTTAATGGATATGGAAAACCAATTAGATAAATTAGATTTTTTAATGCAATCTATGGTAAAAACATCCAGACTAGA
GACAGGTATAATCACACTATCTAAAAAGAAAAATTTAATTTATGAAACAATTGCTACAGCACTTAGTGGAATTTTGTTTG
ATGCTGAAAAAAAGAATATTGAAGTTACAGTTGATTGTGACCCAAATTTATATATAATTCATGACAAGAAATGGACTTCT
GAAGCTATTTTTAATATATTAGATAATGCTGTAAAATACACAAATTCTAATGGTAAGATACATGTAGCTACAGAATGTTG
GGTTATGTATACAAAAATAGATATTATTGATAATGGAAAAGGAATATCAGAAAGTCATCAAGCAGAAATCTTTAAAAGAT
TTTATCGTGAAGAAGATGTCCATGACATAGAAGGTATTGGAATAGGTCTCTATCTTTCAAGAAAAATTATATCTCTTCAA
GGTGGCTATATTAAAGTTACATCAGATATTGGAAAAGGGTCGACTTTTTCTATTTTCTTACCTAATAAATAA

Upstream 100 bases:

>100_bases
ACATCTGTTATAAGTAGGATTAGAAGCAAAATTGAAAAAGACAATCTTAAGTATATCAAAACGGTATATGGTATGGGATA
TATGTGGTTAGGTGAAAGAA

Downstream 100 bases:

>100_bases
ATTTTTAAATATTTCATTTGTAATGATTCTGCAACATTTTGGTTTTATACTGTATTTACAAGATGTTAAGGAGGTATTAT
TATGAGTATTTTACAAGTAA

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MNFKKFSFSSIYLIIAVGIIFTAILFSISIYLITGDLKLIALLLIYTMVLCGFIALIIFLLHKKIVIFCSKICHTLDSMM
NSEDNIEIELEEETILSRINHRLIRMYEVIQENRNSIAIEKADLQELVSDISHQIKTPIANLKMINTTLLNQTFKTEIQK
DFLMDMENQLDKLDFLMQSMVKTSRLETGIITLSKKKNLIYETIATALSGILFDAEKKNIEVTVDCDPNLYIIHDKKWTS
EAIFNILDNAVKYTNSNGKIHVATECWVMYTKIDIIDNGKGISESHQAEIFKRFYREEDVHDIEGIGIGLYLSRKIISLQ
GGYIKVTSDIGKGSTFSIFLPNK

Sequences:

>Translated_343_residues
MNFKKFSFSSIYLIIAVGIIFTAILFSISIYLITGDLKLIALLLIYTMVLCGFIALIIFLLHKKIVIFCSKICHTLDSMM
NSEDNIEIELEEETILSRINHRLIRMYEVIQENRNSIAIEKADLQELVSDISHQIKTPIANLKMINTTLLNQTFKTEIQK
DFLMDMENQLDKLDFLMQSMVKTSRLETGIITLSKKKNLIYETIATALSGILFDAEKKNIEVTVDCDPNLYIIHDKKWTS
EAIFNILDNAVKYTNSNGKIHVATECWVMYTKIDIIDNGKGISESHQAEIFKRFYREEDVHDIEGIGIGLYLSRKIISLQ
GGYIKVTSDIGKGSTFSIFLPNK
>Mature_343_residues
MNFKKFSFSSIYLIIAVGIIFTAILFSISIYLITGDLKLIALLLIYTMVLCGFIALIIFLLHKKIVIFCSKICHTLDSMM
NSEDNIEIELEEETILSRINHRLIRMYEVIQENRNSIAIEKADLQELVSDISHQIKTPIANLKMINTTLLNQTFKTEIQK
DFLMDMENQLDKLDFLMQSMVKTSRLETGIITLSKKKNLIYETIATALSGILFDAEKKNIEVTVDCDPNLYIIHDKKWTS
EAIFNILDNAVKYTNSNGKIHVATECWVMYTKIDIIDNGKGISESHQAEIFKRFYREEDVHDIEGIGIGLYLSRKIISLQ
GGYIKVTSDIGKGSTFSIFLPNK

Specific function: This Protein Is Involved In Several Diverse Cellular Processes, Such As The Functioning Of Acetohydroxyacid Synthetase I, In The Biosynthesis Of Isoleucine And Valine, The Traj Protein Activation Activity For Tra Gene Expression In F Plasmid, And The Syn

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790346, Length=223, Percent_Identity=26.457399103139, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788549, Length=236, Percent_Identity=27.9661016949153, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1786783, Length=266, Percent_Identity=26.3157894736842, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1786912, Length=262, Percent_Identity=23.6641221374046, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789149, Length=224, Percent_Identity=27.6785714285714, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI48994928, Length=245, Percent_Identity=26.530612244898, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1786600, Length=223, Percent_Identity=23.3183856502242, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790436, Length=222, Percent_Identity=24.3243243243243, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788279, Length=310, Percent_Identity=23.2258064516129, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790861, Length=209, Percent_Identity=22.9665071770335, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI145693157, Length=292, Percent_Identity=21.5753424657534, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39205; Mature: 39205

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFKKFSFSSIYLIIAVGIIFTAILFSISIYLITGDLKLIALLLIYTMVLCGFIALIIFL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
LHKKIVIFCSKICHTLDSMMNSEDNIEIELEEETILSRINHRLIRMYEVIQENRNSIAIE
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
KADLQELVSDISHQIKTPIANLKMINTTLLNQTFKTEIQKDFLMDMENQLDKLDFLMQSM
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKTSRLETGIITLSKKKNLIYETIATALSGILFDAEKKNIEVTVDCDPNLYIIHDKKWTS
HHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCEEEEECCCCHH
EAIFNILDNAVKYTNSNGKIHVATECWVMYTKIDIIDNGKGISESHQAEIFKRFYREEDV
HHHHHHHHHHHHEECCCCEEEEEEEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCC
HDIEGIGIGLYLSRKIISLQGGYIKVTSDIGKGSTFSIFLPNK
CHHCCCEEHHEEHHHHEEECCCEEEEEECCCCCCEEEEECCCC
>Mature Secondary Structure
MNFKKFSFSSIYLIIAVGIIFTAILFSISIYLITGDLKLIALLLIYTMVLCGFIALIIFL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
LHKKIVIFCSKICHTLDSMMNSEDNIEIELEEETILSRINHRLIRMYEVIQENRNSIAIE
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
KADLQELVSDISHQIKTPIANLKMINTTLLNQTFKTEIQKDFLMDMENQLDKLDFLMQSM
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKTSRLETGIITLSKKKNLIYETIATALSGILFDAEKKNIEVTVDCDPNLYIIHDKKWTS
HHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCEEEEECCCCHH
EAIFNILDNAVKYTNSNGKIHVATECWVMYTKIDIIDNGKGISESHQAEIFKRFYREEDV
HHHHHHHHHHHHEECCCCEEEEEEEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCC
HDIEGIGIGLYLSRKIISLQGGYIKVTSDIGKGSTFSIFLPNK
CHHCCCEEHHEEHHHHEEECCCEEEEEECCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8535519; 8905231; 3141423 [H]