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The map label for this gene is walR [H]

Identifier: 126699568

GI number: 126699568

Start: 2258943

End: 2259629

Strand: Direct

Name: walR [H]

Synonym: CD1959

Alternate gene names: 126699568

Gene position: 2258943-2259629 (Clockwise)

Preceding gene: 126699567

Following gene: 126699569

Centisome position: 52.65

GC content: 24.75

Gene sequence:

>687_bases
ATGGAAAAAATATTAGTAGTAGAAGATGATTCTATATTAAATAAAACTCTATCATATAACCTAATTGAAGATGGATATAT
AATTACTTCAAAATTTACAGCTAAATCTGCACTGAAGTCTATTTTTGAATGTGAATTTGATTTAATAATTTTGGATATTA
ATTTACCAGATAAAAGTGGGTTTGAATTGTGTAATGAAATAAAGGGAAATTACAATATACCAATAATTTTTTTAACTGCT
AATGATATGGAATGTGATATGATTAAAGGCTATGAACTTGGAGCTTTGGATTATATAACAAAACCATTTAATATCAATAT
ATTTAAACAAAAAATTAAAGCTTTTTTAAATCATCTTACAATAAAAACAAAACAAGATTACTATAGGGATGGATATCTTG
AAATTAACTTTTCTGAGTTATCTGCCAATATAAATGGAAATCAAATTATATTTACACCATTAGAATATCGTACTTTAAAA
CTGCTTACTGAAAATCCTAAAAGTATTTTAACAAGGAAAGTACTTTTAGAAAAACTCTGGGATATAGATGCTAACTTTGT
AGATGAACATACTTTAACATCTGTTATAAGTAGGATTAGAAGCAAAATTGAAAAAGACAATCTTAAGTATATCAAAACGG
TATATGGTATGGGATATATGTGGTTAGGTGAAAGAAATGAATTTTAA

Upstream 100 bases:

>100_bases
TATATAAATTTTTAAATACTTTTTCTCGTTTATAACAATTCAGCAATGTTTTTAGTCTATAATTGACATTATAAAATATT
AAACTAAAAGGAGTAACTGT

Downstream 100 bases:

>100_bases
AAAATTTTCTTTTAGTTCTATTTATTTAATAATTGCTGTTGGTATAATTTTTACAGCTATTTTATTTAGTATCTCAATTT
ATCTAATAACTGGTGATTTA

Product: two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MEKILVVEDDSILNKTLSYNLIEDGYIITSKFTAKSALKSIFECEFDLIILDINLPDKSGFELCNEIKGNYNIPIIFLTA
NDMECDMIKGYELGALDYITKPFNINIFKQKIKAFLNHLTIKTKQDYYRDGYLEINFSELSANINGNQIIFTPLEYRTLK
LLTENPKSILTRKVLLEKLWDIDANFVDEHTLTSVISRIRSKIEKDNLKYIKTVYGMGYMWLGERNEF

Sequences:

>Translated_228_residues
MEKILVVEDDSILNKTLSYNLIEDGYIITSKFTAKSALKSIFECEFDLIILDINLPDKSGFELCNEIKGNYNIPIIFLTA
NDMECDMIKGYELGALDYITKPFNINIFKQKIKAFLNHLTIKTKQDYYRDGYLEINFSELSANINGNQIIFTPLEYRTLK
LLTENPKSILTRKVLLEKLWDIDANFVDEHTLTSVISRIRSKIEKDNLKYIKTVYGMGYMWLGERNEF
>Mature_228_residues
MEKILVVEDDSILNKTLSYNLIEDGYIITSKFTAKSALKSIFECEFDLIILDINLPDKSGFELCNEIKGNYNIPIIFLTA
NDMECDMIKGYELGALDYITKPFNINIFKQKIKAFLNHLTIKTKQDYYRDGYLEINFSELSANINGNQIIFTPLEYRTLK
LLTENPKSILTRKVLLEKLWDIDANFVDEHTLTSVISRIRSKIEKDNLKYIKTVYGMGYMWLGERNEF

Specific function: Member of the two-component regulatory system walK/walR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=222, Percent_Identity=33.3333333333333, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1790552, Length=219, Percent_Identity=32.8767123287671, Blast_Score=112, Evalue=1e-26,
Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=31.5789473684211, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=31.8777292576419, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1786911, Length=231, Percent_Identity=28.1385281385281, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=32.3275862068966, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1789402, Length=229, Percent_Identity=28.82096069869, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=28.9592760180996, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786599, Length=221, Percent_Identity=28.0542986425339, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=30.3571428571429, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1787229, Length=223, Percent_Identity=30.4932735426009, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=28.5067873303167, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=28.6324786324786, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=26.0683760683761, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26546; Mature: 26546

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKILVVEDDSILNKTLSYNLIEDGYIITSKFTAKSALKSIFECEFDLIILDINLPDKSG
CCEEEEEECCHHHHHHHEEEEEECCEEEEECHHHHHHHHHHHHCCEEEEEEEEECCCCCH
FELCNEIKGNYNIPIIFLTANDMECDMIKGYELGALDYITKPFNINIFKQKIKAFLNHLT
HHHHHHCCCCCCCEEEEEECCCCCEEEECCCCCCCHHHCCCCCCCHHHHHHHHHHHHHCE
IKTKQDYYRDGYLEINFSELSANINGNQIIFTPLEYRTLKLLTENPKSILTRKVLLEKLW
EEECHHHCCCCEEEEEHHHEECCCCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHH
DIDANFVDEHTLTSVISRIRSKIEKDNLKYIKTVYGMGYMWLGERNEF
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCCCC
>Mature Secondary Structure
MEKILVVEDDSILNKTLSYNLIEDGYIITSKFTAKSALKSIFECEFDLIILDINLPDKSG
CCEEEEEECCHHHHHHHEEEEEECCEEEEECHHHHHHHHHHHHCCEEEEEEEEECCCCCH
FELCNEIKGNYNIPIIFLTANDMECDMIKGYELGALDYITKPFNINIFKQKIKAFLNHLT
HHHHHHCCCCCCCEEEEEECCCCCEEEECCCCCCCHHHCCCCCCCHHHHHHHHHHHHHCE
IKTKQDYYRDGYLEINFSELSANINGNQIIFTPLEYRTLKLLTENPKSILTRKVLLEKLW
EEECHHHCCCCEEEEEHHHEECCCCCCEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHH
DIDANFVDEHTLTSVISRIRSKIEKDNLKYIKTVYGMGYMWLGERNEF
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA