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The map label for this gene is iap [H]

Identifier: 126699466

GI number: 126699466

Start: 2147674

End: 2149836

Strand: Direct

Name: iap [H]

Synonym: CD1857

Alternate gene names: 126699466

Gene position: 2147674-2149836 (Clockwise)

Preceding gene: 126699465

Following gene: 126699467

Centisome position: 50.06

GC content: 35.04

Gene sequence:

>2163_bases
ATGGGAAAGAAACTGAAAAAGGACTTTAAGGAAAGGCAAAGGGCAAGGATTGAAAAGGAAACGCTGCAAAGTAATATGGG
AATTGAGCCTGAAGAAAGTAAGTTAAAGTATAACGATGATTACAGAGGGAAAATTGTTCATGATAAAGACAGATTCCAAG
ATAAGGTGCATGAGAAAACAAGCAAAATGACCTCTGACAGTGAACCAGTTAGAGGGACTTCCAAAAGAAATGCAAGATAT
AGAGCTTCCAATAAGGATAGCATAACTTCTTCAACTGAAACTGGAGGTGTAAGTCAGGAAGAAATCGGGAAAGCGGATTA
TGGTACGGAGGTTAAGGATGGAAAAATCTATGATCCCTTAGGAAAAGACCTTGATAATGACGGAATCATAGATAGATATG
ACAATGATTTTAGGGACAGCGACTATTTTGAGTCAACCTATGATGTAGATGGATTAAAAAAAGATGAGATTAGCGGAAAT
CCGGTAAATAAGCAAAACACTCAAAAGAAAAATTATAAGAGAAAAAACTATTCCGATAAGCTCTATACAAGAAAGAAGGA
CAAAGAAGCTAAAGAGGAAAAAGCAGATAATAAAAAAAGCGGAAAAGAAGCCGTTCTTGATAGAGAAAAGAAAAACAGGC
TTTCTAAAGAACAGGAAACAATTTTCGAGAATAAGACTTCTAAAGTATCTGCTTTATCAGGCTTAGCAAAAGGAAACGAA
ACCGTAAGAGATTATTTATCTCATGGAAGTGATGAAAATCAAGGGGTAGAGGCAGGAGAAAAGACAGCCGATACAAGCTC
AAAACTCATTCATGGCATTAAGAACTACTCGGATAAGAAAAGAACAAAGAAAGGATATGACCTTACAAATAAGGACTATA
AAATCAGAAAGCGAAAATCCAAATTAGAGTTTCGAGATGCCAAAGAGGAACTGAAAAAGACGGAGGAGTATCAAAAAGCA
AATAACTTTAAACGATTTCAAAAGAGAAAGCAGATGAAAGATTCCATTAAAAGGCAGAATAAGTCAAGGCTTAGAGATCG
CATTAAGGAAGGGCTTATCGGCAGTCTTAAAAGTTCAAAGGAAGTTATATTAAGAAAAACGAAGGGACTTATGATTATTT
TCATAGGTCTTATTCTTTTGAGAACTTTCTTCATTAACTTTGCAGGGACAGGAATGATAGGCTTTATGAACTCTACAAGT
ACAGTTCTTACAACAAGTTATTTATCAAAGCCTAATGTTCTCACAGAAATTCATCAACAATTTTCTAGTATGGAGCAAGG
ATTACAAGATGAGCTTGAAAGTGTTGAAGAAAATTATCCCGGCTATGATGAGTATATTGTCAATAAAGAGGGAGATATTG
GTCATAATACCCATGAGCTTTTATCCTACATTACATCAAGGTTCGGAGAAGTAAAGAATGTATCAGAAGTAAGCTCTGTA
TTAGATGAGCTTTTTAAGTCCATATATAGGCTTGAGTATAAGGAAGAAATTGAAATCAGATACAGGACAGTTACAGAAAC
CTATACTGATGAAGATGGAAACGAATATACCGAAAGCCATGAAGAACCTTATGAGTATAAGAAACTCATTGTAACTCTTT
ATAAAAGAGAAATGGATAGTGTTGTTCGAGAAGTGTTTCAAAATTATCCAGATAATGTGAAACATTATGAAGCATTACTT
GCAAGTCTTGGTAATATGAGTGACTTTTTTGGAAGTGGAAGTAATGATTATTCTGAAATAATAAACAATCCTAATTTTGG
CAATCCGGGAATAGCTTTCAATGAAGAAACGGTTAAACGACTTTTCTCAGAAGCAGAAAGACATATAGGAAAGAGGTATG
TTTTTGGTGCAAATGGGCCGTCAAATTTTGACTGCTCTTCATTTGTGTGTTGGAGCTTTACTCATTCAGGTATTAAAAAT
ATGCCAAGAACAACAGCTTGGAGAATTTATACGGATTACTGTAATCCTGTAAGTACAGGTGAAGCCAAGGCAGGAGATAT
AATATTCTTTAAAAATACCTATAATAGTGGAAGCCCGATTTCTCATGTAGGTATATATGCCGGAAATGGGATGATGATAC
ATGCAGGGGATCCTATTCAATATACTTCTATTAACTCACCATATTGGAGAGAACATTTTTATGGGTTTGGAAGACCAAGA
TAG

Upstream 100 bases:

>100_bases
TTCTTTGGAAACACCATTGTTCCTTTCCTTGATAAGTTCCCAAAAGACACAATACTTTATCAGAAGATGACAACCAAGCC
TGAAGAAGTGAGGTAGGCTT

Downstream 100 bases:

>100_bases
GAGGATACAATTTGAAAAAAGAACTGACAGCAGTAAAAAATAGAATAAAGAAATTGAAAGATAAAAAGGCTCTGATTGAT
GAAGAATTGGAGCCTTTGTT

Product: conjugative transposon cell wall hydrolase

Products: NA

Alternate protein names: Invasion-associated protein [H]

Number of amino acids: Translated: 720; Mature: 719

Protein sequence:

>720_residues
MGKKLKKDFKERQRARIEKETLQSNMGIEPEESKLKYNDDYRGKIVHDKDRFQDKVHEKTSKMTSDSEPVRGTSKRNARY
RASNKDSITSSTETGGVSQEEIGKADYGTEVKDGKIYDPLGKDLDNDGIIDRYDNDFRDSDYFESTYDVDGLKKDEISGN
PVNKQNTQKKNYKRKNYSDKLYTRKKDKEAKEEKADNKKSGKEAVLDREKKNRLSKEQETIFENKTSKVSALSGLAKGNE
TVRDYLSHGSDENQGVEAGEKTADTSSKLIHGIKNYSDKKRTKKGYDLTNKDYKIRKRKSKLEFRDAKEELKKTEEYQKA
NNFKRFQKRKQMKDSIKRQNKSRLRDRIKEGLIGSLKSSKEVILRKTKGLMIIFIGLILLRTFFINFAGTGMIGFMNSTS
TVLTTSYLSKPNVLTEIHQQFSSMEQGLQDELESVEENYPGYDEYIVNKEGDIGHNTHELLSYITSRFGEVKNVSEVSSV
LDELFKSIYRLEYKEEIEIRYRTVTETYTDEDGNEYTESHEEPYEYKKLIVTLYKREMDSVVREVFQNYPDNVKHYEALL
ASLGNMSDFFGSGSNDYSEIINNPNFGNPGIAFNEETVKRLFSEAERHIGKRYVFGANGPSNFDCSSFVCWSFTHSGIKN
MPRTTAWRIYTDYCNPVSTGEAKAGDIIFFKNTYNSGSPISHVGIYAGNGMMIHAGDPIQYTSINSPYWREHFYGFGRPR

Sequences:

>Translated_720_residues
MGKKLKKDFKERQRARIEKETLQSNMGIEPEESKLKYNDDYRGKIVHDKDRFQDKVHEKTSKMTSDSEPVRGTSKRNARY
RASNKDSITSSTETGGVSQEEIGKADYGTEVKDGKIYDPLGKDLDNDGIIDRYDNDFRDSDYFESTYDVDGLKKDEISGN
PVNKQNTQKKNYKRKNYSDKLYTRKKDKEAKEEKADNKKSGKEAVLDREKKNRLSKEQETIFENKTSKVSALSGLAKGNE
TVRDYLSHGSDENQGVEAGEKTADTSSKLIHGIKNYSDKKRTKKGYDLTNKDYKIRKRKSKLEFRDAKEELKKTEEYQKA
NNFKRFQKRKQMKDSIKRQNKSRLRDRIKEGLIGSLKSSKEVILRKTKGLMIIFIGLILLRTFFINFAGTGMIGFMNSTS
TVLTTSYLSKPNVLTEIHQQFSSMEQGLQDELESVEENYPGYDEYIVNKEGDIGHNTHELLSYITSRFGEVKNVSEVSSV
LDELFKSIYRLEYKEEIEIRYRTVTETYTDEDGNEYTESHEEPYEYKKLIVTLYKREMDSVVREVFQNYPDNVKHYEALL
ASLGNMSDFFGSGSNDYSEIINNPNFGNPGIAFNEETVKRLFSEAERHIGKRYVFGANGPSNFDCSSFVCWSFTHSGIKN
MPRTTAWRIYTDYCNPVSTGEAKAGDIIFFKNTYNSGSPISHVGIYAGNGMMIHAGDPIQYTSINSPYWREHFYGFGRPR
>Mature_719_residues
GKKLKKDFKERQRARIEKETLQSNMGIEPEESKLKYNDDYRGKIVHDKDRFQDKVHEKTSKMTSDSEPVRGTSKRNARYR
ASNKDSITSSTETGGVSQEEIGKADYGTEVKDGKIYDPLGKDLDNDGIIDRYDNDFRDSDYFESTYDVDGLKKDEISGNP
VNKQNTQKKNYKRKNYSDKLYTRKKDKEAKEEKADNKKSGKEAVLDREKKNRLSKEQETIFENKTSKVSALSGLAKGNET
VRDYLSHGSDENQGVEAGEKTADTSSKLIHGIKNYSDKKRTKKGYDLTNKDYKIRKRKSKLEFRDAKEELKKTEEYQKAN
NFKRFQKRKQMKDSIKRQNKSRLRDRIKEGLIGSLKSSKEVILRKTKGLMIIFIGLILLRTFFINFAGTGMIGFMNSTST
VLTTSYLSKPNVLTEIHQQFSSMEQGLQDELESVEENYPGYDEYIVNKEGDIGHNTHELLSYITSRFGEVKNVSEVSSVL
DELFKSIYRLEYKEEIEIRYRTVTETYTDEDGNEYTESHEEPYEYKKLIVTLYKREMDSVVREVFQNYPDNVKHYEALLA
SLGNMSDFFGSGSNDYSEIINNPNFGNPGIAFNEETVKRLFSEAERHIGKRYVFGANGPSNFDCSSFVCWSFTHSGIKNM
PRTTAWRIYTDYCNPVSTGEAKAGDIIFFKNTYNSGSPISHVGIYAGNGMMIHAGDPIQYTSINSPYWREHFYGFGRPR

Specific function: This major extracellular protein may be involved in the invasion of non-professional phagocytic cells by Listeria [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1787944, Length=128, Percent_Identity=32.8125, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786421, Length=129, Percent_Identity=29.4573643410853, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482
- InterPro:   IPR003646
- InterPro:   IPR013247 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60; PF08239 SH3_3 [H]

EC number: NA

Molecular weight: Translated: 82976; Mature: 82845

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKKLKKDFKERQRARIEKETLQSNMGIEPEESKLKYNDDYRGKIVHDKDRFQDKVHEKT
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHH
SKMTSDSEPVRGTSKRNARYRASNKDSITSSTETGGVSQEEIGKADYGTEVKDGKIYDPL
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCEECCC
GKDLDNDGIIDRYDNDFRDSDYFESTYDVDGLKKDEISGNPVNKQNTQKKNYKRKNYSDK
CCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHH
LYTRKKDKEAKEEKADNKKSGKEAVLDREKKNRLSKEQETIFENKTSKVSALSGLAKGNE
HHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHH
TVRDYLSHGSDENQGVEAGEKTADTSSKLIHGIKNYSDKKRTKKGYDLTNKDYKIRKRKS
HHHHHHHCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
KLEFRDAKEELKKTEEYQKANNFKRFQKRKQMKDSIKRQNKSRLRDRIKEGLIGSLKSSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
EVILRKTKGLMIIFIGLILLRTFFINFAGTGMIGFMNSTSTVLTTSYLSKPNVLTEIHQQ
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCCCHHHHHHHHH
FSSMEQGLQDELESVEENYPGYDEYIVNKEGDIGHNTHELLSYITSRFGEVKNVSEVSSV
HHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
LDELFKSIYRLEYKEEIEIRYRTVTETYTDEDGNEYTESHEEPYEYKKLIVTLYKREMDS
HHHHHHHHHHHCCHHHHEEEEEEEHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHH
VVREVFQNYPDNVKHYEALLASLGNMSDFFGSGSNDYSEIINNPNFGNPGIAFNEETVKR
HHHHHHHCCCCCHHHHHHHHHHHCCHHHHHCCCCCCHHHHHCCCCCCCCCCCCCHHHHHH
LFSEAERHIGKRYVFGANGPSNFDCSSFVCWSFTHSGIKNMPRTTAWRIYTDYCNPVSTG
HHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCC
EAKAGDIIFFKNTYNSGSPISHVGIYAGNGMMIHAGDPIQYTSINSPYWREHFYGFGRPR
CCCCCCEEEEECCCCCCCCCCEEEEEECCEEEEECCCCEEECCCCCCHHHHHHCCCCCCC
>Mature Secondary Structure 
GKKLKKDFKERQRARIEKETLQSNMGIEPEESKLKYNDDYRGKIVHDKDRFQDKVHEKT
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHH
SKMTSDSEPVRGTSKRNARYRASNKDSITSSTETGGVSQEEIGKADYGTEVKDGKIYDPL
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCEECCC
GKDLDNDGIIDRYDNDFRDSDYFESTYDVDGLKKDEISGNPVNKQNTQKKNYKRKNYSDK
CCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHH
LYTRKKDKEAKEEKADNKKSGKEAVLDREKKNRLSKEQETIFENKTSKVSALSGLAKGNE
HHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHH
TVRDYLSHGSDENQGVEAGEKTADTSSKLIHGIKNYSDKKRTKKGYDLTNKDYKIRKRKS
HHHHHHHCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
KLEFRDAKEELKKTEEYQKANNFKRFQKRKQMKDSIKRQNKSRLRDRIKEGLIGSLKSSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
EVILRKTKGLMIIFIGLILLRTFFINFAGTGMIGFMNSTSTVLTTSYLSKPNVLTEIHQQ
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCCCHHHHHHHHH
FSSMEQGLQDELESVEENYPGYDEYIVNKEGDIGHNTHELLSYITSRFGEVKNVSEVSSV
HHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
LDELFKSIYRLEYKEEIEIRYRTVTETYTDEDGNEYTESHEEPYEYKKLIVTLYKREMDS
HHHHHHHHHHHCCHHHHEEEEEEEHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHH
VVREVFQNYPDNVKHYEALLASLGNMSDFFGSGSNDYSEIINNPNFGNPGIAFNEETVKR
HHHHHHHCCCCCHHHHHHHHHHHCCHHHHHCCCCCCHHHHHCCCCCCCCCCCCCHHHHHH
LFSEAERHIGKRYVFGANGPSNFDCSSFVCWSFTHSGIKNMPRTTAWRIYTDYCNPVSTG
HHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCC
EAKAGDIIFFKNTYNSGSPISHVGIYAGNGMMIHAGDPIQYTSINSPYWREHFYGFGRPR
CCCCCCEEEEECCCCCCCCCCEEEEEECCEEEEECCCCEEECCCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1514809; 1459966 [H]