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The map label for this gene is aroK [H]

Identifier: 126699447

GI number: 126699447

Start: 2127794

End: 2128327

Strand: Direct

Name: aroK [H]

Synonym: CD1838

Alternate gene names: 126699447

Gene position: 2127794-2128327 (Clockwise)

Preceding gene: 126699446

Following gene: 126699448

Centisome position: 49.6

GC content: 24.34

Gene sequence:

>534_bases
ATGATAAATAAAACAAAAGAAAAATTGATATTAATAGGTATGCCAGGTAGTGGAAAAACTACAATTGGTAAACTTTTGGC
CAAAGAATATAATTGTAGTTTCTGTGATATGGATGATTATATAATTCAAATATCTCAAAAAAGTATAGCAGAGTTGTTTT
CAGAAGGAGAAGATATCTTTAGGAACTATGAGACTCAAGCATGTAGAGAACTTTCTATAAGTGATAAAACAGTGATATCT
ACAGGTGGAGGTGTAATAAAAAAGGATGTTAATATGGAAATACTAAAAGAAACAGGTATAATAATTTTTATTGATAGACC
TATACAAAAGATTTTGGAAGATATAAATATTAATTCAAGACCATTATTAAAAAACGGAAAAGATAGATTGTATAATCTTT
ACAATGAGAGAATAAATCTTTATAAAAAATTTTCAGATATAGAGATTTTAAATGATAAATCATTAAATAATGCTGTATAT
AATATTACAAATGCAGTCAGTGAAAATTTTAAATTTGACTTTAAAGAAAAATAA

Upstream 100 bases:

>100_bases
TAAAATCTCAGGAAATTTGGCAAGATACTAAAATAGATAATAGTATTTTAGATGTTATATATAATGAACTAAAATTAGAA
TTTTTGTAAGGGAGATTGTT

Downstream 100 bases:

>100_bases
TCTAGGGGGAAGTAAAAATAATGAATATTGTTATTGTAGGACTAGGAGTTATAGGAGGCTCTTTTGCTAAAGCATTAAAA
AAAGCTGGATATGAAAATGT

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MINKTKEKLILIGMPGSGKTTIGKLLAKEYNCSFCDMDDYIIQISQKSIAELFSEGEDIFRNYETQACRELSISDKTVIS
TGGGVIKKDVNMEILKETGIIIFIDRPIQKILEDININSRPLLKNGKDRLYNLYNERINLYKKFSDIEILNDKSLNNAVY
NITNAVSENFKFDFKEK

Sequences:

>Translated_177_residues
MINKTKEKLILIGMPGSGKTTIGKLLAKEYNCSFCDMDDYIIQISQKSIAELFSEGEDIFRNYETQACRELSISDKTVIS
TGGGVIKKDVNMEILKETGIIIFIDRPIQKILEDININSRPLLKNGKDRLYNLYNERINLYKKFSDIEILNDKSLNNAVY
NITNAVSENFKFDFKEK
>Mature_177_residues
MINKTKEKLILIGMPGSGKTTIGKLLAKEYNCSFCDMDDYIIQISQKSIAELFSEGEDIFRNYETQACRELSISDKTVIS
TGGGVIKKDVNMEILKETGIIIFIDRPIQKILEDININSRPLLKNGKDRLYNLYNERINLYKKFSDIEILNDKSLNNAVY
NITNAVSENFKFDFKEK

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Homo sapiens, GI153792148, Length=178, Percent_Identity=29.2134831460674, Blast_Score=68, Evalue=5e-12,
Organism=Escherichia coli, GI87082255, Length=161, Percent_Identity=32.2981366459627, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1786587, Length=171, Percent_Identity=28.0701754385965, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 20293; Mature: 20293

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINKTKEKLILIGMPGSGKTTIGKLLAKEYNCSFCDMDDYIIQISQKSIAELFSEGEDIF
CCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEECCCHHHEEECHHHHHHHHHCCHHHH
RNYETQACRELSISDKTVISTGGGVIKKDVNMEILKETGIIIFIDRPIQKILEDININSR
HHHHHHHHHHCCCCCCEEEECCCCEEEECCCCEEHHHCCEEEEECCHHHHHHHHCCCCCC
PLLKNGKDRLYNLYNERINLYKKFSDIEILNDKSLNNAVYNITNAVSENFKFDFKEK
CCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MINKTKEKLILIGMPGSGKTTIGKLLAKEYNCSFCDMDDYIIQISQKSIAELFSEGEDIF
CCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEECCCHHHEEECHHHHHHHHHCCHHHH
RNYETQACRELSISDKTVISTGGGVIKKDVNMEILKETGIIIFIDRPIQKILEDININSR
HHHHHHHHHHCCCCCCEEEECCCCEEEECCCCEEHHHCCEEEEECCHHHHHHHHCCCCCC
PLLKNGKDRLYNLYNERINLYKKFSDIEILNDKSLNNAVYNITNAVSENFKFDFKEK
CCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA