Click here to switch to the map view.

The map label for this gene is aroB [H]

Identifier: 126699442

GI number: 126699442

Start: 2122293

End: 2123357

Strand: Direct

Name: aroB [H]

Synonym: CD1833

Alternate gene names: 126699442

Gene position: 2122293-2123357 (Clockwise)

Preceding gene: 126699441

Following gene: 126699443

Centisome position: 49.47

GC content: 26.29

Gene sequence:

>1065_bases
GTGGAAGAAAAACTATTAGTAAATTTAAAAGAAAATAGCTACAATATATTTATTAAAAAAAATATACTAAAGAATATAGG
AGAAGAAATAAAAAAAATATATTTTGGAAATAAGATTTTTATTGTAACTGATGAAAATATAGCAAAATTATACTTGGATA
AAGTAAAAAATAATTTAAGTGAATCTGGATTTGAAATTAAATCTTTAATATTAAAATCTGGTGAAGAAACAAAATCATTT
AATACTCTTCCTAAAATATACGATAGTTTACTTGACTTTAAGTTAACTAGAAAAGATTTGATTATTACTTTAGGAGGAGG
GGTAATAGGTGATTTAGGTGGATTTGCAGCAGCAACTTTTTTAAGAGGTATAAGTTTTATTCAAATTCCAACATCTTTAT
TAGCACAAGTTGATAGTTCTGTAGGTGGAAAAGTTGGAGTTGACCTTGAGAGAGGCAAAAACTTAGTGGGAAGCTTTTAC
CAACCAAAGGCTGTGTTTATCGACCCAAATGTATTATTATCACTTCCAGAAAAATTCTATAGAGATGGAATGGCAGAAGT
TATAAAATATGGATGTATAAAAGACAAAACTTTTTTCAATAAACTTTTAAGTTTAAAAAATAGAGAAGAAGTAATGCAAC
ATATAGAATACATTATACATAAATGTTGCTTTATTAAAAAAACTGTAGTTGAAGCTGATGAAAAAGACTTTGGAGATAGA
ATGCTTCTAAACTTTGGCCATACATTAGGTCATGCTATTGAGAAATACTACAATTTTACGGGTTATACCCATGGAGAAGC
TGTTGCCATAGGAATGTATAAGATAACTTTAGAAAGTGAAAAGATAGGAATTACAAAAAAAGGGACATCAGAACTTATAA
AATCAATTTTAATGAATTATAATTTGCCTTATGAGATTGAATTAAGAGATAATAAATCTATAGTAGATGCTATATCTCTT
GATAAAAAAAATCTAGGTGATACATTAAAAATAATACTTTTAAAAGATATTGGAGAGAGTATTATATATAATACTACTTC
TAAATTTTTTCAGGAGGTAAGATAA

Upstream 100 bases:

>100_bases
ATCGATTAAGCCAAATGAATATGATGAATTGATAAGTGAATTAAAGACTATCGCATCAGCAGTTGGTAGAGAAATATAAT
CTATAAAAGGATGGTTAAAC

Downstream 100 bases:

>100_bases
TGGGAAGTCTAAAAATATATCCAAGTAAATTATCTGGAGATGTAAAAATACCACCATCAAAAAGTATGGCACATAGGGCA
GTTATTTGTTCATCTCTAAG

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MEEKLLVNLKENSYNIFIKKNILKNIGEEIKKIYFGNKIFIVTDENIAKLYLDKVKNNLSESGFEIKSLILKSGEETKSF
NTLPKIYDSLLDFKLTRKDLIITLGGGVIGDLGGFAAATFLRGISFIQIPTSLLAQVDSSVGGKVGVDLERGKNLVGSFY
QPKAVFIDPNVLLSLPEKFYRDGMAEVIKYGCIKDKTFFNKLLSLKNREEVMQHIEYIIHKCCFIKKTVVEADEKDFGDR
MLLNFGHTLGHAIEKYYNFTGYTHGEAVAIGMYKITLESEKIGITKKGTSELIKSILMNYNLPYEIELRDNKSIVDAISL
DKKNLGDTLKIILLKDIGESIIYNTTSKFFQEVR

Sequences:

>Translated_354_residues
MEEKLLVNLKENSYNIFIKKNILKNIGEEIKKIYFGNKIFIVTDENIAKLYLDKVKNNLSESGFEIKSLILKSGEETKSF
NTLPKIYDSLLDFKLTRKDLIITLGGGVIGDLGGFAAATFLRGISFIQIPTSLLAQVDSSVGGKVGVDLERGKNLVGSFY
QPKAVFIDPNVLLSLPEKFYRDGMAEVIKYGCIKDKTFFNKLLSLKNREEVMQHIEYIIHKCCFIKKTVVEADEKDFGDR
MLLNFGHTLGHAIEKYYNFTGYTHGEAVAIGMYKITLESEKIGITKKGTSELIKSILMNYNLPYEIELRDNKSIVDAISL
DKKNLGDTLKIILLKDIGESIIYNTTSKFFQEVR
>Mature_354_residues
MEEKLLVNLKENSYNIFIKKNILKNIGEEIKKIYFGNKIFIVTDENIAKLYLDKVKNNLSESGFEIKSLILKSGEETKSF
NTLPKIYDSLLDFKLTRKDLIITLGGGVIGDLGGFAAATFLRGISFIQIPTSLLAQVDSSVGGKVGVDLERGKNLVGSFY
QPKAVFIDPNVLLSLPEKFYRDGMAEVIKYGCIKDKTFFNKLLSLKNREEVMQHIEYIIHKCCFIKKTVVEADEKDFGDR
MLLNFGHTLGHAIEKYYNFTGYTHGEAVAIGMYKITLESEKIGITKKGTSELIKSILMNYNLPYEIELRDNKSIVDAISL
DKKNLGDTLKIILLKDIGESIIYNTTSKFFQEVR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=350, Percent_Identity=40.2857142857143, Blast_Score=247, Evalue=6e-67,
Organism=Saccharomyces cerevisiae, GI6320332, Length=382, Percent_Identity=33.7696335078534, Blast_Score=187, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 40053; Mature: 40053

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEKLLVNLKENSYNIFIKKNILKNIGEEIKKIYFGNKIFIVTDENIAKLYLDKVKNNLS
CCCCEEEEEECCCEEEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHH
ESGFEIKSLILKSGEETKSFNTLPKIYDSLLDFKLTRKDLIITLGGGVIGDLGGFAAATF
HCCHHHHHHHHHCCCCCHHCCHHHHHHHHHHCCEECCCEEEEEECCCHHHHHHHHHHHHH
LRGISFIQIPTSLLAQVDSSVGGKVGVDLERGKNLVGSFYQPKAVFIDPNVLLSLPEKFY
HHCCHHHHHHHHHHHHHHHCCCCEECCCHHHCCHHHCCCCCCEEEEECCHHHHHCCHHHH
RDGMAEVIKYGCIKDKTFFNKLLSLKNREEVMQHIEYIIHKCCFIKKTVVEADEKDFGDR
HCCHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
MLLNFGHTLGHAIEKYYNFTGYTHGEAVAIGMYKITLESEKIGITKKGTSELIKSILMNY
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHCC
NLPYEIELRDNKSIVDAISLDKKNLGDTLKIILLKDIGESIIYNTTSKFFQEVR
CCCEEEEECCCCCHHHHHHCCCCCCCCCEEEEEHHHCCHHHHHCCHHHHHHHCC
>Mature Secondary Structure
MEEKLLVNLKENSYNIFIKKNILKNIGEEIKKIYFGNKIFIVTDENIAKLYLDKVKNNLS
CCCCEEEEEECCCEEEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHH
ESGFEIKSLILKSGEETKSFNTLPKIYDSLLDFKLTRKDLIITLGGGVIGDLGGFAAATF
HCCHHHHHHHHHCCCCCHHCCHHHHHHHHHHCCEECCCEEEEEECCCHHHHHHHHHHHHH
LRGISFIQIPTSLLAQVDSSVGGKVGVDLERGKNLVGSFYQPKAVFIDPNVLLSLPEKFY
HHCCHHHHHHHHHHHHHHHCCCCEECCCHHHCCHHHCCCCCCEEEEECCHHHHHCCHHHH
RDGMAEVIKYGCIKDKTFFNKLLSLKNREEVMQHIEYIIHKCCFIKKTVVEADEKDFGDR
HCCHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
MLLNFGHTLGHAIEKYYNFTGYTHGEAVAIGMYKITLESEKIGITKKGTSELIKSILMNY
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHCC
NLPYEIELRDNKSIVDAISLDKKNLGDTLKIILLKDIGESIIYNTTSKFFQEVR
CCCEEEEECCCCCHHHHHHCCCCCCCCCEEEEEHHHCCHHHHHCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA