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The map label for this gene is alsT [H]

Identifier: 126699302

GI number: 126699302

Start: 1967847

End: 1969298

Strand: Direct

Name: alsT [H]

Synonym: CD1696

Alternate gene names: 126699302

Gene position: 1967847-1969298 (Clockwise)

Preceding gene: 126699299

Following gene: 126699307

Centisome position: 45.87

GC content: 31.54

Gene sequence:

>1452_bases
ATGGATTTTTTCAATGGTATTTTAACGAGTATTAACAATGCAGTAGTATATGTAAACAATTACTTATGGTCGTATATCTT
AATTATAATGTTAGTTGTAATTGGTATTTACTTTACTATTAAAACAAATTTTGTACAATTCAGATATTTTATAGAAATGT
TTAGACTTCTGGGTGATGGTACAGCGAATAAAAATGCAAAAAAGGAAGGAAAAATCTCTTCATTTCAAGCATTTTGTATA
AGTACATCTTCAAGAGTTGGAACTGGAAATATAGCTGGAATAGCAATTGCAGTGGTAGCAGGAGGACCTGGTGCTGTATT
TTGGATGTGGCTTATAGCATTAATTGGTTCTGCATCAAGCTTTGTTGAGAGTACATTAGCTCAGATTTACAAAGTGAAAG
ATGGTCAAGCTTTTAGAGGTGGACCAGCGTATTATATGGAACAAGGTCTAAATAAAAAATGGATGGGTATTTTATTCTCA
ATACTTATAACTATATGTTATGGTTTTGTATTTAATGCAGTTCAAGCAAATACTGTTTCACTTGCATTTAATAATGCATT
TGGAATAAGTAAAATGGCTATGGGAATAGGTCTTGGAATTTTAACTGCAATAGTTATTTTTGGTGGAGTGCATAGAGTTG
CAAAAGTTTCTGAAATAATAGTTCCTGTATTTGCAGGATTATATATATTAGTTGCTTTGGCTATAGTTGTAATGAATATA
ACAGAGATACCAAGTGTTATAGCATTGATAGTTGAAAGTGCATTTGATTTTAAAGGAATGGCGATTGGTACATTTATGGG
AGTTGTAATGACTGGAGTGAAGAGAGGTCTATTTTCTAATGAAGCAGGTATGGGTAGTGCTCCTAATGCTGCTGCAACAG
CACATGTAACTCATCCTGTAAAACAAGGTTTAATTCAATCTTTAGGTGTTTTTACAGATACTATAATAATATGTAGTTGT
ACAGCATTCATGGTATTATTATATTCAGGTTATAGTAGTAGTGGAGCAACTGGAATTGAATTAGCTCAAGAAGCTTTAAC
TCATCATATAGGACCAGTTGGAAATATATTTATAGCAGTTTGTATATTCTTGTTTGCATTTAGTTCTATAGTTGGTAATT
ACTATTATGGTGAATCAAATATGGAGTTTATGAGTGGAAGTAAGACTAAACTTAATGTATTTAGAGTTTTTGTTGTAGGT
ATGGTTTTATTTGGTTCACTTACTCAAGTAGATGTAGTTTGGAATCTTGCAGACTTATTTATGGCATTGATGGCGATAAT
AAACTTAATAGCAATAGCACTTTTAGGAAAATATGCATTTATTGCTTTAAAAGATTATACAAGTCAAAAAAAATCAGGAA
TAAAAGACCCTGTGTTTATTGCAGATGAAATAGAAGGCCTAGAAAAGGTATCAGAGTGGCATAGGGAATTATCTGAGGAA
CATTTAGTATAA

Upstream 100 bases:

>100_bases
ATTATAATTAAATTAATGAATTTTTAACAAGGAATTATTCATTTTTTTGATTTTAAGATTTATTGAGAAAACAAAACTAA
ATAGGGGGGTAATTAATATA

Downstream 100 bases:

>100_bases
AATTATAAAACCATTTTGAAAGATTAGAGTATGTATATACTTTATATGAATATAATATTGAATTAATTTATATTACTGGA
ATTTTTAATTCCAGTAATAT

Product: sodium:amino acid symporter

Products: Na (I) [Cytoplasm]; L-alanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MDFFNGILTSINNAVVYVNNYLWSYILIIMLVVIGIYFTIKTNFVQFRYFIEMFRLLGDGTANKNAKKEGKISSFQAFCI
STSSRVGTGNIAGIAIAVVAGGPGAVFWMWLIALIGSASSFVESTLAQIYKVKDGQAFRGGPAYYMEQGLNKKWMGILFS
ILITICYGFVFNAVQANTVSLAFNNAFGISKMAMGIGLGILTAIVIFGGVHRVAKVSEIIVPVFAGLYILVALAIVVMNI
TEIPSVIALIVESAFDFKGMAIGTFMGVVMTGVKRGLFSNEAGMGSAPNAAATAHVTHPVKQGLIQSLGVFTDTIIICSC
TAFMVLLYSGYSSSGATGIELAQEALTHHIGPVGNIFIAVCIFLFAFSSIVGNYYYGESNMEFMSGSKTKLNVFRVFVVG
MVLFGSLTQVDVVWNLADLFMALMAIINLIAIALLGKYAFIALKDYTSQKKSGIKDPVFIADEIEGLEKVSEWHRELSEE
HLV

Sequences:

>Translated_483_residues
MDFFNGILTSINNAVVYVNNYLWSYILIIMLVVIGIYFTIKTNFVQFRYFIEMFRLLGDGTANKNAKKEGKISSFQAFCI
STSSRVGTGNIAGIAIAVVAGGPGAVFWMWLIALIGSASSFVESTLAQIYKVKDGQAFRGGPAYYMEQGLNKKWMGILFS
ILITICYGFVFNAVQANTVSLAFNNAFGISKMAMGIGLGILTAIVIFGGVHRVAKVSEIIVPVFAGLYILVALAIVVMNI
TEIPSVIALIVESAFDFKGMAIGTFMGVVMTGVKRGLFSNEAGMGSAPNAAATAHVTHPVKQGLIQSLGVFTDTIIICSC
TAFMVLLYSGYSSSGATGIELAQEALTHHIGPVGNIFIAVCIFLFAFSSIVGNYYYGESNMEFMSGSKTKLNVFRVFVVG
MVLFGSLTQVDVVWNLADLFMALMAIINLIAIALLGKYAFIALKDYTSQKKSGIKDPVFIADEIEGLEKVSEWHRELSEE
HLV
>Mature_483_residues
MDFFNGILTSINNAVVYVNNYLWSYILIIMLVVIGIYFTIKTNFVQFRYFIEMFRLLGDGTANKNAKKEGKISSFQAFCI
STSSRVGTGNIAGIAIAVVAGGPGAVFWMWLIALIGSASSFVESTLAQIYKVKDGQAFRGGPAYYMEQGLNKKWMGILFS
ILITICYGFVFNAVQANTVSLAFNNAFGISKMAMGIGLGILTAIVIFGGVHRVAKVSEIIVPVFAGLYILVALAIVVMNI
TEIPSVIALIVESAFDFKGMAIGTFMGVVMTGVKRGLFSNEAGMGSAPNAAATAHVTHPVKQGLIQSLGVFTDTIIICSC
TAFMVLLYSGYSSSGATGIELAQEALTHHIGPVGNIFIAVCIFLFAFSSIVGNYYYGESNMEFMSGSKTKLNVFRVFVVG
MVLFGSLTQVDVVWNLADLFMALMAIINLIAIALLGKYAFIALKDYTSQKKSGIKDPVFIADEIEGLEKVSEWHRELSEE
HLV

Specific function: Unknown

COG id: COG1115

COG function: function code E; Na+/alanine symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:alanine (SAF) symporter family [H]

Homologues:

Organism=Escherichia coli, GI1786188, Length=474, Percent_Identity=41.7721518987342, Blast_Score=343, Evalue=1e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001463 [H]

Pfam domain/function: PF01235 Na_Ala_symp [H]

EC number: NA

Molecular weight: Translated: 52239; Mature: 52239

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: PS00873 NA_ALANINE_SYMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFFNGILTSINNAVVYVNNYLWSYILIIMLVVIGIYFTIKTNFVQFRYFIEMFRLLGDG
CCHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TANKNAKKEGKISSFQAFCISTSSRVGTGNIAGIAIAVVAGGPGAVFWMWLIALIGSASS
CCCCCCCCCCCHHHHHHHEEECCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCHHH
FVESTLAQIYKVKDGQAFRGGPAYYMEQGLNKKWMGILFSILITICYGFVFNAVQANTVS
HHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
LAFNNAFGISKMAMGIGLGILTAIVIFGGVHRVAKVSEIIVPVFAGLYILVALAIVVMNI
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEIPSVIALIVESAFDFKGMAIGTFMGVVMTGVKRGLFSNEAGMGSAPNAAATAHVTHPV
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
KQGLIQSLGVFTDTIIICSCTAFMVLLYSGYSSSGATGIELAQEALTHHIGPVGNIFIAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
CIFLFAFSSIVGNYYYGESNMEFMSGSKTKLNVFRVFVVGMVLFGSLTQVDVVWNLADLF
HHHHHHHHHHHCCEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
MALMAIINLIAIALLGKYAFIALKDYTSQKKSGIKDPVFIADEIEGLEKVSEWHRELSEE
HHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHH
HLV
CCC
>Mature Secondary Structure
MDFFNGILTSINNAVVYVNNYLWSYILIIMLVVIGIYFTIKTNFVQFRYFIEMFRLLGDG
CCHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TANKNAKKEGKISSFQAFCISTSSRVGTGNIAGIAIAVVAGGPGAVFWMWLIALIGSASS
CCCCCCCCCCCHHHHHHHEEECCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCHHH
FVESTLAQIYKVKDGQAFRGGPAYYMEQGLNKKWMGILFSILITICYGFVFNAVQANTVS
HHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
LAFNNAFGISKMAMGIGLGILTAIVIFGGVHRVAKVSEIIVPVFAGLYILVALAIVVMNI
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEIPSVIALIVESAFDFKGMAIGTFMGVVMTGVKRGLFSNEAGMGSAPNAAATAHVTHPV
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
KQGLIQSLGVFTDTIIICSCTAFMVLLYSGYSSSGATGIELAQEALTHHIGPVGNIFIAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
CIFLFAFSSIVGNYYYGESNMEFMSGSKTKLNVFRVFVVGMVLFGSLTQVDVVWNLADLF
HHHHHHHHHHHCCEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
MALMAIINLIAIALLGKYAFIALKDYTSQKKSGIKDPVFIADEIEGLEKVSEWHRELSEE
HHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHH
HLV
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-alanine [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-alanine [Periplasm] = Na (I) [Cytoplasm] + L-alanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969507; 9384377; 7710280 [H]