Click here to switch to the map view.

The map label for this gene is deoC

Identifier: 126699105

GI number: 126699105

Start: 1739817

End: 1740476

Strand: Direct

Name: deoC

Synonym: CD1502

Alternate gene names: 126699105

Gene position: 1739817-1740476 (Clockwise)

Preceding gene: 126699104

Following gene: 126699106

Centisome position: 40.55

GC content: 28.79

Gene sequence:

>660_bases
ATGAAACATATATTAAAAACAGTAGACCATACTATTTTAAAAGCTACAACTACATGGGAAGATATTAAAATTTTATGTGA
TGAAGCTGTAGATATGAGTGTAGCATCAGTTTGCATACCACCATCATATGTGAAAAGAGCATCAGAATATCTAAAAGGTA
AAATAAAGATATGTACAGTGATAGGGTTCCCTTTGGGATATCAAACTACTGCTACAAAAGTATTTGAAGCAAAAGATGCT
ATTGAAAATGGAGCAGATGAAGTTGATATGGTTGTAAACATTTCAGATATAAAAAATAAAGATTATGATAATATAGGAAA
AGAAATAAAAGAAATAAAAAAAGCTATAGGAGATAAAGTATTAAAAGTCATTATAGAGACATGTTATTTAGATGAAGATG
AAAAAATAAAAATGTGTGAAATAGTAACAATGTCAGGTTCAGATTTTATAAAAACATCTACTGGAATGGGAACAGGTGGA
GCTACTTTAGAAGATATAAAGCTTATGAAAGAGCATGTTGGAAAAAATGTAAAAATAAAAGCTGCAGGGGGAGTTAAATC
AATTTCTGATGCAGAAAAATTTATAGAGGCAGGAGCAGAAAGGTTAGGAACTAGCTCAATATGTAAAATATTAAAAAATG
AAGATACAACAGATTATTAA

Upstream 100 bases:

>100_bases
TTAAAGTTGAAGAGGTTGATATGATACTGAATATTGCAAAAAGAAAATTGCATTTAAAAAAGTAATCTAATTATATTAAT
TATAAATTTAGGAGGATTTT

Downstream 100 bases:

>100_bases
AGTTTTTAACTTATGGATAGGATTACAAAAATTAAAATTTAATTATAAATATAAAGAACAACAAACAGAGGGAATTTTCC
CTCTGTTTTTTATTTAGTAT

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase; DERA; Deoxyriboaldolase

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MKHILKTVDHTILKATTTWEDIKILCDEAVDMSVASVCIPPSYVKRASEYLKGKIKICTVIGFPLGYQTTATKVFEAKDA
IENGADEVDMVVNISDIKNKDYDNIGKEIKEIKKAIGDKVLKVIIETCYLDEDEKIKMCEIVTMSGSDFIKTSTGMGTGG
ATLEDIKLMKEHVGKNVKIKAAGGVKSISDAEKFIEAGAERLGTSSICKILKNEDTTDY

Sequences:

>Translated_219_residues
MKHILKTVDHTILKATTTWEDIKILCDEAVDMSVASVCIPPSYVKRASEYLKGKIKICTVIGFPLGYQTTATKVFEAKDA
IENGADEVDMVVNISDIKNKDYDNIGKEIKEIKKAIGDKVLKVIIETCYLDEDEKIKMCEIVTMSGSDFIKTSTGMGTGG
ATLEDIKLMKEHVGKNVKIKAAGGVKSISDAEKFIEAGAERLGTSSICKILKNEDTTDY
>Mature_219_residues
MKHILKTVDHTILKATTTWEDIKILCDEAVDMSVASVCIPPSYVKRASEYLKGKIKICTVIGFPLGYQTTATKVFEAKDA
IENGADEVDMVVNISDIKNKDYDNIGKEIKEIKKAIGDKVLKVIIETCYLDEDEKIKMCEIVTMSGSDFIKTSTGMGTGG
ATLEDIKLMKEHVGKNVKIKAAGGVKSISDAEKFIEAGAERLGTSSICKILKNEDTTDY

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily

Homologues:

Organism=Homo sapiens, GI116063554, Length=184, Percent_Identity=34.2391304347826, Blast_Score=91, Evalue=9e-19,
Organism=Escherichia coli, GI1790841, Length=214, Percent_Identity=35.0467289719626, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17533015, Length=222, Percent_Identity=29.2792792792793, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI19922098, Length=188, Percent_Identity=34.5744680851064, Blast_Score=78, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOC_CLOD6 (Q18C22)

Other databases:

- EMBL:   AM180355
- RefSeq:   YP_001088002.1
- ProteinModelPortal:   Q18C22
- SMR:   Q18C22
- STRING:   Q18C22
- GeneID:   4916590
- GenomeReviews:   AM180355_GR
- KEGG:   cdf:CD1502
- NMPDR:   fig|1496.1.peg.1172
- eggNOG:   COG0274
- HOGENOM:   HBG636421
- OMA:   EEKIAMC
- ProtClustDB:   PRK00507
- GO:   GO:0005737
- HAMAP:   MF_00114
- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915
- InterPro:   IPR022979
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10889
- PIRSF:   PIRSF001357
- TIGRFAMs:   TIGR00126

Pfam domain/function: PF01791 DeoC

EC number: =4.1.2.4

Molecular weight: Translated: 23995; Mature: 23995

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: ACT_SITE 151-151 ACT_SITE 180-180

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHILKTVDHTILKATTTWEDIKILCDEAVDMSVASVCIPPSYVKRASEYLKGKIKICTV
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEE
IGFPLGYQTTATKVFEAKDAIENGADEVDMVVNISDIKNKDYDNIGKEIKEIKKAIGDKV
EECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHH
LKVIIETCYLDEDEKIKMCEIVTMSGSDFIKTSTGMGTGGATLEDIKLMKEHVGKNVKIK
HHHHHHHHHCCCCCCEEEEEEEEECCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCEEEE
AAGGVKSISDAEKFIEAGAERLGTSSICKILKNEDTTDY
ECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKHILKTVDHTILKATTTWEDIKILCDEAVDMSVASVCIPPSYVKRASEYLKGKIKICTV
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEE
IGFPLGYQTTATKVFEAKDAIENGADEVDMVVNISDIKNKDYDNIGKEIKEIKKAIGDKV
EECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHH
LKVIIETCYLDEDEKIKMCEIVTMSGSDFIKTSTGMGTGGATLEDIKLMKEHVGKNVKIK
HHHHHHHHHCCCCCCEEEEEEEEECCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCEEEE
AAGGVKSISDAEKFIEAGAERLGTSSICKILKNEDTTDY
ECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA