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The map label for this gene is pabA [H]

Identifier: 126699049

GI number: 126699049

Start: 1676146

End: 1676730

Strand: Direct

Name: pabA [H]

Synonym: CD1445

Alternate gene names: 126699049

Gene position: 1676146-1676730 (Clockwise)

Preceding gene: 126699048

Following gene: 126699050

Centisome position: 39.07

GC content: 31.62

Gene sequence:

>585_bases
ATGATTCTTATGATAGACAATTATGATTCTTTTGTATACAACCTAGTCCAATATATAGAAGAATTAGGGGAAACAGTTGT
AGTAAAAAGAAATAATGAAATCAAAATAAGTGACATTGAAGAACTAAATCCAGAGGTAATTGTGTTATCTCCAGGACCGT
GTTCTCCAAAAGAAGCTGGTATTTGCATAGATATTGTTGAGCATTTTAAGGGGAAAAAACCTATACTAGGAATTTGTTTA
GGTCACCAAACTATTGGACATGTTTTTGGAGGAGATATTATAAAAGCACAACAGCCTGTGCATGGAAAAGTATATAGTAT
CAACCATACTAATAAAGGAGTTTTTAGGGGACTTAAAAATCCTTTAAATGTCACTAGGTATCATTCACTAATAATTGATT
CCAATACAGTTCCAAAAGAATTAGAAATTACAGCAATTACTGATAAAGGGGAAATAATGGGGATTAGGCATAAGAAATAT
TTAATAGAAGGAGTACAGTTTCATCCAGAAGCTATTTTGTCAGAGTATGGTCATGAAATGCTTAAAAATTTTATAACAGA
AGCTAGAGAAAGGGTACATGTGTAA

Upstream 100 bases:

>100_bases
AAGCTTTAGATATGTTTATTCCAAAAATGATTGAAAAAGGTTTTAAATTTGTAACAGTTTCTGAGTTGATAAAATAATTT
TTAGGGGGGAGATTTACAGT

Downstream 100 bases:

>100_bases
TATGATAAGAGAGATAAATACTAAATTAAATTCTTTTGAGATATTTACTATTTTTAGAAATGAACATGACAGTTTTATAT
TAGACAGTGCTATGGATAAA

Product: para-aminobenzoate synthase glutamine amidotransferase component II

Products: NA

Alternate protein names: Para-aminobenzoate synthase glutamine amidotransferase component II; ADC synthase; Anthranilate synthase component II [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MILMIDNYDSFVYNLVQYIEELGETVVVKRNNEIKISDIEELNPEVIVLSPGPCSPKEAGICIDIVEHFKGKKPILGICL
GHQTIGHVFGGDIIKAQQPVHGKVYSINHTNKGVFRGLKNPLNVTRYHSLIIDSNTVPKELEITAITDKGEIMGIRHKKY
LIEGVQFHPEAILSEYGHEMLKNFITEARERVHV

Sequences:

>Translated_194_residues
MILMIDNYDSFVYNLVQYIEELGETVVVKRNNEIKISDIEELNPEVIVLSPGPCSPKEAGICIDIVEHFKGKKPILGICL
GHQTIGHVFGGDIIKAQQPVHGKVYSINHTNKGVFRGLKNPLNVTRYHSLIIDSNTVPKELEITAITDKGEIMGIRHKKY
LIEGVQFHPEAILSEYGHEMLKNFITEARERVHV
>Mature_194_residues
MILMIDNYDSFVYNLVQYIEELGETVVVKRNNEIKISDIEELNPEVIVLSPGPCSPKEAGICIDIVEHFKGKKPILGICL
GHQTIGHVFGGDIIKAQQPVHGKVYSINHTNKGVFRGLKNPLNVTRYHSLIIDSNTVPKELEITAITDKGEIMGIRHKKY
LIEGVQFHPEAILSEYGHEMLKNFITEARERVHV

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine and also involved in the synthesis of anthranilate [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=185, Percent_Identity=55.1351351351351, Blast_Score=244, Evalue=2e-66,
Organism=Escherichia coli, GI1787517, Length=195, Percent_Identity=42.0512820512821, Blast_Score=152, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6322638, Length=185, Percent_Identity=47.027027027027, Blast_Score=190, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6324361, Length=211, Percent_Identity=30.8056872037915, Blast_Score=86, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85; =4.1.3.27 [H]

Molecular weight: Translated: 21881; Mature: 21881

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILMIDNYDSFVYNLVQYIEELGETVVVKRNNEIKISDIEELNPEVIVLSPGPCSPKEAG
CEEEEECCHHHHHHHHHHHHHHCCEEEEECCCEEEEEEHHHCCCCEEEECCCCCCCCCCC
ICIDIVEHFKGKKPILGICLGHQTIGHVFGGDIIKAQQPVHGKVYSINHTNKGVFRGLKN
EEHHHHHHCCCCCCEEEEEECCHHHHHHHCCCEEECCCCCCCEEEEECCCCCHHHHHCCC
PLNVTRYHSLIIDSNTVPKELEITAITDKGEIMGIRHKKYLIEGVQFHPEAILSEYGHEM
CCCHHEEEEEEECCCCCCCEEEEEEEECCCCEEEEEHHHHHHHCCCCCHHHHHHHHHHHH
LKNFITEARERVHV
HHHHHHHHHHHCCC
>Mature Secondary Structure
MILMIDNYDSFVYNLVQYIEELGETVVVKRNNEIKISDIEELNPEVIVLSPGPCSPKEAG
CEEEEECCHHHHHHHHHHHHHHCCEEEEECCCEEEEEEHHHCCCCEEEECCCCCCCCCCC
ICIDIVEHFKGKKPILGICLGHQTIGHVFGGDIIKAQQPVHGKVYSINHTNKGVFRGLKN
EEHHHHHHCCCCCCEEEEEECCHHHHHHHCCCEEECCCCCCCEEEEECCCCCHHHHHCCC
PLNVTRYHSLIIDSNTVPKELEITAITDKGEIMGIRHKKYLIEGVQFHPEAILSEYGHEM
CCCHHEEEEEEECCCCCCCEEEEEEEECCCCEEEEEHHHHHHHCCCCCHHHHHHHHHHHH
LKNFITEARERVHV
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]