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The map label for this gene is rpiR [C]

Identifier: 126698936

GI number: 126698936

Start: 1552219

End: 1552971

Strand: Direct

Name: rpiR [C]

Synonym: CD1337

Alternate gene names: 126698936

Gene position: 1552219-1552971 (Clockwise)

Preceding gene: 126698935

Following gene: 126698937

Centisome position: 36.18

GC content: 25.5

Gene sequence:

>753_bases
ATGAACCTAATAGACAAATTAGATATAAATCAAAAAAAATTATCTACAAATGAAATATCTCTTTTAAACTATTTTCTAAA
AAATTCTGAAAAAATAAATCAAAAAAAGATTAAAGATATAGCAAATGAAACTTTTAATTCGACTGCATACATAGTAAGGT
TTTGTCAGAAGCTCGGCTTTTCTGGATATAGTGAATTTAAAAACTTTTTAGTTTTTTCATATTCAAATAGAAATGAAAGA
AATAAGGAGTTTACTAAAAGTCAAAGTGATATTTTTACTGATGTTATGGATACACAAAATTTAATAAATGTAGAGAATAT
AGATATGTGTTTAAATGAAATACATAATTCTAAGCATATATATTTTTTTGGTGTTGGGTCTTCTAGATTAGTATGTACTG
AAATGTCTCAACGTTTTTCAGCTATAGGTGTAAATGTAAAATACTATGATGATTCAACTCTCATGTATTTGGCTGCATCA
AATATTACTAAAGATGACCTTGTAATTGCTGTATCTATGTCTGGAGAGACTGCTCAAGTTATTAAGGCATGTAATATAGC
AAAAACAAATCAAGTTAAAGTAATTTCTCTGACAAATATAAGTGTCAATTCATTATCAAATATAGCTGATATAAAATTAT
TTGTATCTTCTCCACAATATAATTTTAATAGTGTTAACTATACGTCTAGAGTGCCAGCACTTTCTCTTATGGAATATATG
TTTCATAAATACATTGAAAAATACAATAGATGA

Upstream 100 bases:

>100_bases
TTGTAGTATAATAAACATAAGATAAATGCTGTATAGTGTATATTTATATAATAAATATGAGAAAGTTGTTTAACTACAAA
TCATTATTATGGAGGTATAA

Downstream 100 bases:

>100_bases
AAAAAATTACAATTTTGAAAAAAATACTAAAATTGAACTATTTTTAATGATTACCTAAAAGTATTCATGTAGAAAACTTT
ATATATTATAATCATCTTAC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MNLIDKLDINQKKLSTNEISLLNYFLKNSEKINQKKIKDIANETFNSTAYIVRFCQKLGFSGYSEFKNFLVFSYSNRNER
NKEFTKSQSDIFTDVMDTQNLINVENIDMCLNEIHNSKHIYFFGVGSSRLVCTEMSQRFSAIGVNVKYYDDSTLMYLAAS
NITKDDLVIAVSMSGETAQVIKACNIAKTNQVKVISLTNISVNSLSNIADIKLFVSSPQYNFNSVNYTSRVPALSLMEYM
FHKYIEKYNR

Sequences:

>Translated_250_residues
MNLIDKLDINQKKLSTNEISLLNYFLKNSEKINQKKIKDIANETFNSTAYIVRFCQKLGFSGYSEFKNFLVFSYSNRNER
NKEFTKSQSDIFTDVMDTQNLINVENIDMCLNEIHNSKHIYFFGVGSSRLVCTEMSQRFSAIGVNVKYYDDSTLMYLAAS
NITKDDLVIAVSMSGETAQVIKACNIAKTNQVKVISLTNISVNSLSNIADIKLFVSSPQYNFNSVNYTSRVPALSLMEYM
FHKYIEKYNR
>Mature_250_residues
MNLIDKLDINQKKLSTNEISLLNYFLKNSEKINQKKIKDIANETFNSTAYIVRFCQKLGFSGYSEFKNFLVFSYSNRNER
NKEFTKSQSDIFTDVMDTQNLINVENIDMCLNEIHNSKHIYFFGVGSSRLVCTEMSQRFSAIGVNVKYYDDSTLMYLAAS
NITKDDLVIAVSMSGETAQVIKACNIAKTNQVKVISLTNISVNSLSNIADIKLFVSSPQYNFNSVNYTSRVPALSLMEYM
FHKYIEKYNR

Specific function: Regulatory Protein Involved In Rpib Gene Repression. Also Involved In Als Operon Repression. [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI87082369, Length=252, Percent_Identity=26.1904761904762, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788159, Length=251, Percent_Identity=25.0996015936255, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788767, Length=252, Percent_Identity=22.6190476190476, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI87082130, Length=248, Percent_Identity=22.1774193548387, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 28680; Mature: 28680

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLIDKLDINQKKLSTNEISLLNYFLKNSEKINQKKIKDIANETFNSTAYIVRFCQKLGF
CCCCCCCCCCHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
SGYSEFKNFLVFSYSNRNERNKEFTKSQSDIFTDVMDTQNLINVENIDMCLNEIHNSKHI
CCHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEE
YFFGVGSSRLVCTEMSQRFSAIGVNVKYYDDSTLMYLAASNITKDDLVIAVSMSGETAQV
EEEECCCCCEEHHHHHHHHHHHEEEEEEECCCEEEEEEECCCCCCCEEEEEEECCCHHHH
IKACNIAKTNQVKVISLTNISVNSLSNIADIKLFVSSPQYNFNSVNYTSRVPALSLMEYM
HHHHCCCCCCCEEEEEEECCCHHHHCCCEEEEEEEECCCCCCCCCCCHHCCCHHHHHHHH
FHKYIEKYNR
HHHHHHHHCC
>Mature Secondary Structure
MNLIDKLDINQKKLSTNEISLLNYFLKNSEKINQKKIKDIANETFNSTAYIVRFCQKLGF
CCCCCCCCCCHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
SGYSEFKNFLVFSYSNRNERNKEFTKSQSDIFTDVMDTQNLINVENIDMCLNEIHNSKHI
CCHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEE
YFFGVGSSRLVCTEMSQRFSAIGVNVKYYDDSTLMYLAASNITKDDLVIAVSMSGETAQV
EEEECCCCCEEHHHHHHHHHHHEEEEEEECCCEEEEEEECCCCCCCEEEEEEECCCHHHH
IKACNIAKTNQVKVISLTNISVNSLSNIADIKLFVSSPQYNFNSVNYTSRVPALSLMEYM
HHHHCCCCCCCEEEEEEECCCHHHHCCCEEEEEEEECCCCCCCCCCCHHCCCHHHHHHHH
FHKYIEKYNR
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8177218; 11792842 [H]