| Definition | Clostridium difficile 630 chromosome, complete genome. |
|---|---|
| Accession | NC_009089 |
| Length | 4,290,252 |
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The map label for this gene is ftsK [H]
Identifier: 126698923
GI number: 126698923
Start: 1534293
End: 1536704
Strand: Direct
Name: ftsK [H]
Synonym: CD1324
Alternate gene names: 126698923
Gene position: 1534293-1536704 (Clockwise)
Preceding gene: 126698922
Following gene: 126698924
Centisome position: 35.76
GC content: 31.01
Gene sequence:
>2412_bases ATGGCCACGAAAAAGAAGAAAAAAAAGAAGGTAAATACCTTAAGTTTTAATGCAGAATATCATAATTTAATAACAATATT TATAGGTGTATTTTTATTATATAGTTTAAATTCTAATTCTATGGGATGGATACCTGTGTTAATGCAAAATCTTTTTAAGG GACTATTTGGAGGGCTTTCAATAGCAATACCATTTATAGTAATTATAACAGGACTTTTAGGATTTTTTGATGGAAATGAA TATATATATAGGCTAAGAAAGACTAAACTATACTACATAATTATTTTATTTATATTTGTATTTTATGGATTATTAAATGC AGGAACTCTTCCTGTAGATAGCCCACTAAAAGGTAACATGTTTGATGATGTTATGAAATTGGGTGTAAGTGGACAAGGTA GTGGTTTGATAGCAACAACTATTGCGTATTATATGAGTAAAATATTTGGTATAGCAGGTGGATGGTTAATAAGTATCTTC GCACTTATACTTTCTGTAATGTTTATATTTAATATTTCTATAAAAGATTTGGTGTCAAATGCAAAATCAAAATCTAAAGC ATCTAAAGACAGCAATTTAACGTTTAAAGATAAAATTGCAAATATGAAAAAATCTGCAATAGATATGATGACTGATGAAG TAGATGATACTACTATAAATAAAAAACCAGGTTTCTTTAAAGGGTTAATGTCAAAAGGTCTTAATAATGATGATGAAGAA GATGAATATTTTGAAGAAGAAAATAGTGATGGTGTAGATGATAAAACTATAAAAATAGTTGGATTTAATAAGGCAGAAGA TGAGTATTTAGAAATATTAGAAGGAACTCAAAGTATGCCAGAGTTAGATGTTTTAAAAGAATTACAAAAAGCTACCAATG AAAATCCAGTTGTAGATACTAAACCAGAAAAAAAAGTTGATATAGCTAAACCTAATTTAAATATAGAAAAAACTCAACCT ATGAGTATTGTAGCAGAGCCAGTTAATGAGGATTATTCAAACTATAAAAAGCCTAGCATTGAGCTTTTAAATAAAGTAAA TAAGAAGTCTGATGAAAATGGTAAAAAGAAAGTGTTGAAAAATGCTTCTCTTTTAGAAAAGACACTATCAGATTTTGGAG TGGAAGCAAAAATTAATCAAGTTACAGTTGGACCTACTATAACAAGATATGAAATACAACCAAGTCCAGGAGTCAAGGTA AGTAAAATTGTAAATTTAACTGATGATATAGCTTTAAGTTTAGCAGCTAAAAGTATAAGAATTGAAGCCCCAATTCCTGG TAAAAGTGCAATTGGAATAGAAGTTCCAAATGAAGAAGCTCAAATGGTTGGTGTGAGAGAAGTTCTAGAAAGTGAAGAAT TTAATAATTTTAACTCTCCTCTTGCAATGGGACTTGGAAAAGACGTAGCAGGAAAAATTATAATTGGAGATATAGGTAAG ATGCCACACTTACTAATAGCTGGTTCTACAGGTTCAGGAAAGAGTGTGTGTGTAAATACATTAATAAGTAGTATTTTATA TAAGGCAAATCCTGATGAAGTAAAATTACTATTAATAGACCCAAAAGTAGTTGAACTTGCAAATTATAATGGAATACCAC ATCTATTGATACCAGTAGTTACTGACCCTAAAAAAGCTGCAAATGCTTTAAATTGGGCAGTTACAGAGATGAATAGAAGG TACAAATTATTTGCAGATGCTCAAGTAAAAGATGTAACAAGTTATAATGAGAAAGCGGAAGAAAAACTTCCTAAAATAGT AATAATAATAGATGAGTTAGCAGATTTAATGATGGCAAGTGCAAATGATGTAGAAGATTATATTTGTAGATTAGCTCAAA TGGCAAGAGCTGCTGGAATGCACTTGATTGTAGCAACTCAAAGACCATCTGTTGACGTTATAACAGGGGTAATAAAGGCT AATATACCATCTAGAATAGCATTTGCAGTATCATCTCAAACTGATTCAAGAACAATCCTTGATATGGGTGGTGCAGAGAA GCTTCTAGGTAAAGGTGATATGTTATTCTATCCACTTGGTGCAGCAAAACCAGTTAGACTTCAAGGGGCATTCATATCAG AGAGTGAGTCGGAAAAAGTAATCGATTTTGTAAAAAGTCAGGTTAAAGATGGAATAAAATATGAAGAAGATATAATTGAA ACTATATCTAAGGTTAATACTTCAAAGGGTAGTGATGAGGATGAGTTTTTGAGTGAAGCGATAGAATTTGTCGTGGAAAG TGGTCAAGCATCTGCCTCTATGCTACAGAGAAGATTTAAAATAGGATTCAATAGAGCAGCTAGACTTATAGATTCTATGG AAGAAAGAGGAATAATTGGAGCAAGTGAGGGAAGTAAACCGAGAAAGGTATTAATAAGCAAACAGGATTTGCAGAATTTA GAAGGTGAATAG
Upstream 100 bases:
>100_bases TATGATATAATGATGTAATAAAGTAGGAGTGTTAGTGTTAAGGCATTAGCACTTTTTGCTGTGAAGGGGTAAAACTTGCT AAAAATAAGGAGTGATATTA
Downstream 100 bases:
>100_bases AATTGTCAGTTATAAAAATAGAAAAAGCACTTAAGCTAGATAAAGTAATATTTGTAGATGTGAGAACTGAAGGAGAATAT GAAGAAGACCATATATTGAA
Product: DNA translocase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 803; Mature: 802
Protein sequence:
>803_residues MATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWIPVLMQNLFKGLFGGLSIAIPFIVIITGLLGFFDGNE YIYRLRKTKLYYIIILFIFVFYGLLNAGTLPVDSPLKGNMFDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIF ALILSVMFIFNISIKDLVSNAKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTTINKKPGFFKGLMSKGLNNDDEE DEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGTQSMPELDVLKELQKATNENPVVDTKPEKKVDIAKPNLNIEKTQP MSIVAEPVNEDYSNYKKPSIELLNKVNKKSDENGKKKVLKNASLLEKTLSDFGVEAKINQVTVGPTITRYEIQPSPGVKV SKIVNLTDDIALSLAAKSIRIEAPIPGKSAIGIEVPNEEAQMVGVREVLESEEFNNFNSPLAMGLGKDVAGKIIIGDIGK MPHLLIAGSTGSGKSVCVNTLISSILYKANPDEVKLLLIDPKVVELANYNGIPHLLIPVVTDPKKAANALNWAVTEMNRR YKLFADAQVKDVTSYNEKAEEKLPKIVIIIDELADLMMASANDVEDYICRLAQMARAAGMHLIVATQRPSVDVITGVIKA NIPSRIAFAVSSQTDSRTILDMGGAEKLLGKGDMLFYPLGAAKPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIE TISKVNTSKGSDEDEFLSEAIEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIGASEGSKPRKVLISKQDLQNL EGE
Sequences:
>Translated_803_residues MATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWIPVLMQNLFKGLFGGLSIAIPFIVIITGLLGFFDGNE YIYRLRKTKLYYIIILFIFVFYGLLNAGTLPVDSPLKGNMFDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIF ALILSVMFIFNISIKDLVSNAKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTTINKKPGFFKGLMSKGLNNDDEE DEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGTQSMPELDVLKELQKATNENPVVDTKPEKKVDIAKPNLNIEKTQP MSIVAEPVNEDYSNYKKPSIELLNKVNKKSDENGKKKVLKNASLLEKTLSDFGVEAKINQVTVGPTITRYEIQPSPGVKV SKIVNLTDDIALSLAAKSIRIEAPIPGKSAIGIEVPNEEAQMVGVREVLESEEFNNFNSPLAMGLGKDVAGKIIIGDIGK MPHLLIAGSTGSGKSVCVNTLISSILYKANPDEVKLLLIDPKVVELANYNGIPHLLIPVVTDPKKAANALNWAVTEMNRR YKLFADAQVKDVTSYNEKAEEKLPKIVIIIDELADLMMASANDVEDYICRLAQMARAAGMHLIVATQRPSVDVITGVIKA NIPSRIAFAVSSQTDSRTILDMGGAEKLLGKGDMLFYPLGAAKPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIE TISKVNTSKGSDEDEFLSEAIEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIGASEGSKPRKVLISKQDLQNL EGE >Mature_802_residues ATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWIPVLMQNLFKGLFGGLSIAIPFIVIITGLLGFFDGNEY IYRLRKTKLYYIIILFIFVFYGLLNAGTLPVDSPLKGNMFDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIFA LILSVMFIFNISIKDLVSNAKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTTINKKPGFFKGLMSKGLNNDDEED EYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGTQSMPELDVLKELQKATNENPVVDTKPEKKVDIAKPNLNIEKTQPM SIVAEPVNEDYSNYKKPSIELLNKVNKKSDENGKKKVLKNASLLEKTLSDFGVEAKINQVTVGPTITRYEIQPSPGVKVS KIVNLTDDIALSLAAKSIRIEAPIPGKSAIGIEVPNEEAQMVGVREVLESEEFNNFNSPLAMGLGKDVAGKIIIGDIGKM PHLLIAGSTGSGKSVCVNTLISSILYKANPDEVKLLLIDPKVVELANYNGIPHLLIPVVTDPKKAANALNWAVTEMNRRY KLFADAQVKDVTSYNEKAEEKLPKIVIIIDELADLMMASANDVEDYICRLAQMARAAGMHLIVATQRPSVDVITGVIKAN IPSRIAFAVSSQTDSRTILDMGGAEKLLGKGDMLFYPLGAAKPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIET ISKVNTSKGSDEDEFLSEAIEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIGASEGSKPRKVLISKQDLQNLE GE
Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind
COG id: COG1674
COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 FtsK domain [H]
Homologues:
Organism=Escherichia coli, GI1787117, Length=486, Percent_Identity=46.5020576131687, Blast_Score=422, Evalue=1e-119,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003593 - InterPro: IPR018541 - InterPro: IPR002543 - InterPro: IPR011991 [H]
Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]
EC number: NA
Molecular weight: Translated: 88314; Mature: 88183
Theoretical pI: Translated: 5.40; Mature: 5.40
Prosite motif: PS50901 FTSK
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 3.4 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 3.0 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWIPVLMQNLFKGLFGGLS CCCCHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH IAIPFIVIITGLLGFFDGNEYIYRLRKTKLYYIIILFIFVFYGLLNAGTLPVDSPLKGNM HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH FDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIFALILSVMFIFNISIKDLVSN HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH AKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTTINKKPGFFKGLMSKGLNNDDEE HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCH DEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGTQSMPELDVLKELQKATNENPVVDT HHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCC KPEKKVDIAKPNLNIEKTQPMSIVAEPVNEDYSNYKKPSIELLNKVNKKSDENGKKKVLK CCCCCEEEECCCCCCCCCCCHHHEECCCCCHHHHCCCCHHHHHHHHHCCCCCCHHHHHHH NASLLEKTLSDFGVEAKINQVTVGPTITRYEIQPSPGVKVSKIVNLTDDIALSLAAKSIR HHHHHHHHHHHCCCCEEEEEEEECCCEEEEEECCCCCCCHHHHHCCHHHHHHHHHHHEEE IEAPIPGKSAIGIEVPNEEAQMVGVREVLESEEFNNFNSPLAMGLGKDVAGKIIIGDIGK EECCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCEEEEECCCC MPHLLIAGSTGSGKSVCVNTLISSILYKANPDEVKLLLIDPKVVELANYNGIPHLLIPVV CCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEHHCCCCCCEEEEEEE TDPKKAANALNWAVTEMNRRYKLFADAQVKDVTSYNEKAEEKLPKIVIIIDELADLMMAS CCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHC ANDVEDYICRLAQMARAAGMHLIVATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTIL CCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEE DMGGAEKLLGKGDMLFYPLGAAKPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIE ECCCHHHHHCCCCEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH TISKVNTSKGSDEDEFLSEAIEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIG HHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE ASEGSKPRKVLISKQDLQNLEGE CCCCCCCCEEEEEHHHHHCCCCC >Mature Secondary Structure ATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWIPVLMQNLFKGLFGGLS CCCHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH IAIPFIVIITGLLGFFDGNEYIYRLRKTKLYYIIILFIFVFYGLLNAGTLPVDSPLKGNM HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH FDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIFALILSVMFIFNISIKDLVSN HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH AKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTTINKKPGFFKGLMSKGLNNDDEE HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCH DEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGTQSMPELDVLKELQKATNENPVVDT HHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCC KPEKKVDIAKPNLNIEKTQPMSIVAEPVNEDYSNYKKPSIELLNKVNKKSDENGKKKVLK CCCCCEEEECCCCCCCCCCCHHHEECCCCCHHHHCCCCHHHHHHHHHCCCCCCHHHHHHH NASLLEKTLSDFGVEAKINQVTVGPTITRYEIQPSPGVKVSKIVNLTDDIALSLAAKSIR HHHHHHHHHHHCCCCEEEEEEEECCCEEEEEECCCCCCCHHHHHCCHHHHHHHHHHHEEE IEAPIPGKSAIGIEVPNEEAQMVGVREVLESEEFNNFNSPLAMGLGKDVAGKIIIGDIGK EECCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCEEEEECCCC MPHLLIAGSTGSGKSVCVNTLISSILYKANPDEVKLLLIDPKVVELANYNGIPHLLIPVV CCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEHHCCCCCCEEEEEEE TDPKKAANALNWAVTEMNRRYKLFADAQVKDVTSYNEKAEEKLPKIVIIIDELADLMMAS CCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHC ANDVEDYICRLAQMARAAGMHLIVATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTIL CCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEE DMGGAEKLLGKGDMLFYPLGAAKPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIE ECCCHHHHHCCCCEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH TISKVNTSKGSDEDEFLSEAIEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIG HHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE ASEGSKPRKVLISKQDLQNLEGE CCCCCCCCEEEEEHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11792842 [H]