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The map label for this gene is dapG [H]

Identifier: 126698921

GI number: 126698921

Start: 1532100

End: 1533323

Strand: Direct

Name: dapG [H]

Synonym: CD1322

Alternate gene names: 126698921

Gene position: 1532100-1533323 (Clockwise)

Preceding gene: 126698920

Following gene: 126698922

Centisome position: 35.71

GC content: 31.7

Gene sequence:

>1224_bases
ATGAGTATTTTAGTGCAAAAGTTTGGTGGGACATCAGTAGAATCATATGAAAAAATGAATGAAGTATGTAAGATAGTAAA
AGCATACAAAAAAAATGATGAAGAATTACAATTAGTATTAGTAGTTTCAGCAATGGGAAGAAAAGGAGCTCCATATGCTA
CAGATACACTTATAAATTTGTGTAGTGCAGTAAATGATGAGCCAAGTAAAAGAGAACTTGATTTAATAATGTCTTGTGGA
GAAATAATATCAGGAACAATTCTTGCTAATTTATTGAATGCACAGGGGATAGATTCTGTTTTCTTTACTGGTCAGCAAGC
AGGTATAATTACAAGTGATGAATATTCTAATGCAAAGATAAAGTATATAAATCCTAAAAAGGTAAAAAGAGCTTTAGATG
ATGGTAAGGTTGTAGTTATAGCTGGGTTCCAGGGTGTAACAGATGATGGAGAAATAACTACTCTTGGAAGAGGCGGAAGC
GATACATCAGCAGTTGCTATTGGTAAAGCTTTAGAATGTGAAACAGTTGAAATTTACACTGATGTGGATGGTATAATGAC
TGCAGACCCTAGAGTAGAACCAAACGCTAAAGTATTGAGTTTTATAGACTATGAGGAAGTATTCCAAATGGCTGACAAAG
GTGCAAAAGTAATACATCCAAGAGCAGTACAGTTGGCTAAAAGTGGAAATATAACTTTAGCCATAAAGAATACAATGAAT
CCAACTTTTGAAGGTACAAAAATAGGTTCTTTATGTAGACACTTAGAAGACAATATAGAATATGAACAAGAAAGAGATTT
TAAGGTTGCTGTTGCAAATAAAGATAGCGTAGCACAAGTTAAGATTAAGTCAGCAGAAGAAGTGTTTACAGAAGTATTAA
ATGAGATAGAAAAGAAACTTATAACTATAGATATGATAAATTTCTTTATATCAGAAAAAGCATTTGTTGTAGAAGATGCT
GATATAAAATCATTAAAGGAAATACTAGATAAATTTGAATTAGATTATGAAGTAAATAGAGACTGTGCTAAGGTAACATT
GATATGTTCAAGAATTGCTGATGAAATGTCTGGTATCATGTCAAAGGTAGTTAGAGGATTATCAAAAGCAGGGGTATCTC
TTTTACAAACATCAGACTCAAATATGACTATATCTTGTTTAGTTAGTGAAGAAGATATGCATACAGCAGTACATGCTATA
CACCAACAATTTTATTTAAAATAA

Upstream 100 bases:

>100_bases
AAAAGATAAGTCATTTTTAGAAGTACCATGGAGAAATGTAAAAAAAATAGGTAATGACATGATAATTATAGAATATGAGG
GATATATTTAGGAGGAAAAA

Downstream 100 bases:

>100_bases
ACTGTATAATACAATTATTTTTTAATCAAATTTAAGAATTTCATATATATCTTAATATATTTGATTTATTTGGTAAAACT
AAATTAAATATAATTTTGAT

Product: aspartate kinase I

Products: NA

Alternate protein names: Aspartate kinase 1; Aspartokinase I [H]

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MSILVQKFGGTSVESYEKMNEVCKIVKAYKKNDEELQLVLVVSAMGRKGAPYATDTLINLCSAVNDEPSKRELDLIMSCG
EIISGTILANLLNAQGIDSVFFTGQQAGIITSDEYSNAKIKYINPKKVKRALDDGKVVVIAGFQGVTDDGEITTLGRGGS
DTSAVAIGKALECETVEIYTDVDGIMTADPRVEPNAKVLSFIDYEEVFQMADKGAKVIHPRAVQLAKSGNITLAIKNTMN
PTFEGTKIGSLCRHLEDNIEYEQERDFKVAVANKDSVAQVKIKSAEEVFTEVLNEIEKKLITIDMINFFISEKAFVVEDA
DIKSLKEILDKFELDYEVNRDCAKVTLICSRIADEMSGIMSKVVRGLSKAGVSLLQTSDSNMTISCLVSEEDMHTAVHAI
HQQFYLK

Sequences:

>Translated_407_residues
MSILVQKFGGTSVESYEKMNEVCKIVKAYKKNDEELQLVLVVSAMGRKGAPYATDTLINLCSAVNDEPSKRELDLIMSCG
EIISGTILANLLNAQGIDSVFFTGQQAGIITSDEYSNAKIKYINPKKVKRALDDGKVVVIAGFQGVTDDGEITTLGRGGS
DTSAVAIGKALECETVEIYTDVDGIMTADPRVEPNAKVLSFIDYEEVFQMADKGAKVIHPRAVQLAKSGNITLAIKNTMN
PTFEGTKIGSLCRHLEDNIEYEQERDFKVAVANKDSVAQVKIKSAEEVFTEVLNEIEKKLITIDMINFFISEKAFVVEDA
DIKSLKEILDKFELDYEVNRDCAKVTLICSRIADEMSGIMSKVVRGLSKAGVSLLQTSDSNMTISCLVSEEDMHTAVHAI
HQQFYLK
>Mature_406_residues
SILVQKFGGTSVESYEKMNEVCKIVKAYKKNDEELQLVLVVSAMGRKGAPYATDTLINLCSAVNDEPSKRELDLIMSCGE
IISGTILANLLNAQGIDSVFFTGQQAGIITSDEYSNAKIKYINPKKVKRALDDGKVVVIAGFQGVTDDGEITTLGRGGSD
TSAVAIGKALECETVEIYTDVDGIMTADPRVEPNAKVLSFIDYEEVFQMADKGAKVIHPRAVQLAKSGNITLAIKNTMNP
TFEGTKIGSLCRHLEDNIEYEQERDFKVAVANKDSVAQVKIKSAEEVFTEVLNEIEKKLITIDMINFFISEKAFVVEDAD
IKSLKEILDKFELDYEVNRDCAKVTLICSRIADEMSGIMSKVVRGLSKAGVSLLQTSDSNMTISCLVSEEDMHTAVHAIH
QQFYLK

Specific function: Catalyzes 2 nonconsecutive reactions in the common biosynthetic pathway leading from Asp to diaminopimelate and Lys, to Met, and to Thr and Ile. [C]

COG id: COG0527

COG function: function code E; Aspartokinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartokinase family [H]

Homologues:

Organism=Escherichia coli, GI1786183, Length=288, Percent_Identity=28.125, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1790455, Length=300, Percent_Identity=27.6666666666667, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790376, Length=176, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320893, Length=379, Percent_Identity=26.9129287598945, Blast_Score=115, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR005260
- InterPro:   IPR001341
- InterPro:   IPR018042 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.4 [H]

Molecular weight: Translated: 44700; Mature: 44569

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00324 ASPARTOKINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILVQKFGGTSVESYEKMNEVCKIVKAYKKNDEELQLVLVVSAMGRKGAPYATDTLINL
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHH
CSAVNDEPSKRELDLIMSCGEIISGTILANLLNAQGIDSVFFTGQQAGIITSDEYSNAKI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEECCCCCCCEE
KYINPKKVKRALDDGKVVVIAGFQGVTDDGEITTLGRGGSDTSAVAIGKALECETVEIYT
EEECHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCCCCCCCCEEECCCCCCCEEEEEE
DVDGIMTADPRVEPNAKVLSFIDYEEVFQMADKGAKVIHPRAVQLAKSGNITLAIKNTMN
CCCCEEECCCCCCCCCCEEEECCHHHHHHHHHCCCEEECCHHHHEECCCCEEEEEECCCC
PTFEGTKIGSLCRHLEDNIEYEQERDFKVAVANKDSVAQVKIKSAEEVFTEVLNEIEKKL
CCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHH
ITIDMINFFISEKAFVVEDADIKSLKEILDKFELDYEVNRDCAKVTLICSRIADEMSGIM
HHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
SKVVRGLSKAGVSLLQTSDSNMTISCLVSEEDMHTAVHAIHQQFYLK
HHHHHHHHHCCCEEEEECCCCEEEEEEECCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SILVQKFGGTSVESYEKMNEVCKIVKAYKKNDEELQLVLVVSAMGRKGAPYATDTLINL
CEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHH
CSAVNDEPSKRELDLIMSCGEIISGTILANLLNAQGIDSVFFTGQQAGIITSDEYSNAKI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEECCCCCCCEE
KYINPKKVKRALDDGKVVVIAGFQGVTDDGEITTLGRGGSDTSAVAIGKALECETVEIYT
EEECHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCCCCCCCCEEECCCCCCCEEEEEE
DVDGIMTADPRVEPNAKVLSFIDYEEVFQMADKGAKVIHPRAVQLAKSGNITLAIKNTMN
CCCCEEECCCCCCCCCCEEEECCHHHHHHHHHCCCEEECCHHHHEECCCCEEEEEECCCC
PTFEGTKIGSLCRHLEDNIEYEQERDFKVAVANKDSVAQVKIKSAEEVFTEVLNEIEKKL
CCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHH
ITIDMINFFISEKAFVVEDADIKSLKEILDKFELDYEVNRDCAKVTLICSRIADEMSGIM
HHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
SKVVRGLSKAGVSLLQTSDSNMTISCLVSEEDMHTAVHAIHQQFYLK
HHHHHHHHHCCCEEEEECCCCEEEEEEECCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8098035; 9384377 [H]