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The map label for this gene is ymxG [H]

Identifier: 126698919

GI number: 126698919

Start: 1530563

End: 1531810

Strand: Direct

Name: ymxG [H]

Synonym: CD1320

Alternate gene names: 126698919

Gene position: 1530563-1531810 (Clockwise)

Preceding gene: 126698918

Following gene: 126698920

Centisome position: 35.68

GC content: 28.12

Gene sequence:

>1248_bases
ATGTATAAGACAAAAATACTGGAAAATGGGCTTACAATAATTGGTGAAGAAATACCATATCTAAAGTCAATAACATTAGG
TATTTGGATAAATGCAGGCTCTAGGATAGAAGAAGCACAGGTGAGTGGAACTTCTCATTTTATAGAGCATATGATGTTTA
AAGGAACCAAAAACAGAACATCAAAAGAGATTGCTAGTTCAATAGATAATTTGGGTGGTCAAATAAATGCATTTACAAGT
AAAGAATGTACATGTTATTATGTAAAACTAATAGATGAGCATATAGATACAGGAATTGATGTATTGAGTGATATGATACT
AAATTCTAAATTTGATAAAAATGATATAGATAAGGAAAGACTTATAATATTGGAAGAACTTAAGATGTATGAAGACTCTC
CAGATGACTTATCTTATGATTTATTAGTGGAAAATATATATGCTAATGATGGATTAGGAATGAATATAATTGGGACAAAA
GAATCTCTGTACAATATAACTAGAGAATCCATGTTAGAATACTTAAATAAGTATTATATTCCAAATAACGCTGTTATTTC
TATAGCTGGAAACTTTAACTTTGATGATATGGTGGAGAAAATCAAATCAAAATTTGGACACTGGGAAAAGAAAAATTTAA
GTATAGACATAAGTGAGGCTAAGTTTAATCCTTGCTTTATATCAAAAAATAAAGATACTGAACAGGTGAACTTAGCTATG
TGCCTAAAAGGTATTCCTTTTGAAAATGATGAAGAAGTCTATTCAATGGCAGTGGTAAATAATATTTTCGGTGGAAGTAT
AAGCTCAAGGCTTTTTCAGAAAATAAGGGAAGAAAAAGGTTTAGTATATTCAATATACTCATCACAGACATTATATAGGA
AATGTGGTGAATTAGGTATATTTGCAAGCATGAGTACAGAAAATTTACAAGATGTATATAATTTAATAAAGAAAGAAATT
GAAAATATAAGAGAAAACTATCTTACAGAAAAAGAAATATCTGAAAGCAAGGAACAGTTAAAAGGAAATTATATATTGGA
TTTAGAAAGTACTAGCAGTAGAATGATGTCTACTGGTAAATCTATGTTACTTAGCAAAAAAGTAAAAACTACAGATGAAA
TACTTGAATGTATAAATAATGTTAATATTAATTCAATAAAGAAGGTTGTTGATAAGGTATTCAATATCGAAAATATTGGT
ACATGTATAGTTGGAAGAGATGTAGAAAAGATTCTACACTTGGATTAA

Upstream 100 bases:

>100_bases
CTGACTTATAATGTAATACATATAAAAAATAAATATAATTAAAACATAGTGTTTTCAATAATCCAATATGAAACAAAGAA
TAAATTGTTAGGAGAATGTA

Downstream 100 bases:

>100_bases
TATTGAAAAAAGTAAATCTCTGGAGGTATAAAATATGAATTTATCTGAAATAGCAGGTAAGGAAATAGTTAACTTGGTCA
CAGGAGAAAGATTGGGGGTC

Product: peptidase

Products: NA

Alternate protein names: ORFP [H]

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MYKTKILENGLTIIGEEIPYLKSITLGIWINAGSRIEEAQVSGTSHFIEHMMFKGTKNRTSKEIASSIDNLGGQINAFTS
KECTCYYVKLIDEHIDTGIDVLSDMILNSKFDKNDIDKERLIILEELKMYEDSPDDLSYDLLVENIYANDGLGMNIIGTK
ESLYNITRESMLEYLNKYYIPNNAVISIAGNFNFDDMVEKIKSKFGHWEKKNLSIDISEAKFNPCFISKNKDTEQVNLAM
CLKGIPFENDEEVYSMAVVNNIFGGSISSRLFQKIREEKGLVYSIYSSQTLYRKCGELGIFASMSTENLQDVYNLIKKEI
ENIRENYLTEKEISESKEQLKGNYILDLESTSSRMMSTGKSMLLSKKVKTTDEILECINNVNINSIKKVVDKVFNIENIG
TCIVGRDVEKILHLD

Sequences:

>Translated_415_residues
MYKTKILENGLTIIGEEIPYLKSITLGIWINAGSRIEEAQVSGTSHFIEHMMFKGTKNRTSKEIASSIDNLGGQINAFTS
KECTCYYVKLIDEHIDTGIDVLSDMILNSKFDKNDIDKERLIILEELKMYEDSPDDLSYDLLVENIYANDGLGMNIIGTK
ESLYNITRESMLEYLNKYYIPNNAVISIAGNFNFDDMVEKIKSKFGHWEKKNLSIDISEAKFNPCFISKNKDTEQVNLAM
CLKGIPFENDEEVYSMAVVNNIFGGSISSRLFQKIREEKGLVYSIYSSQTLYRKCGELGIFASMSTENLQDVYNLIKKEI
ENIRENYLTEKEISESKEQLKGNYILDLESTSSRMMSTGKSMLLSKKVKTTDEILECINNVNINSIKKVVDKVFNIENIG
TCIVGRDVEKILHLD
>Mature_415_residues
MYKTKILENGLTIIGEEIPYLKSITLGIWINAGSRIEEAQVSGTSHFIEHMMFKGTKNRTSKEIASSIDNLGGQINAFTS
KECTCYYVKLIDEHIDTGIDVLSDMILNSKFDKNDIDKERLIILEELKMYEDSPDDLSYDLLVENIYANDGLGMNIIGTK
ESLYNITRESMLEYLNKYYIPNNAVISIAGNFNFDDMVEKIKSKFGHWEKKNLSIDISEAKFNPCFISKNKDTEQVNLAM
CLKGIPFENDEEVYSMAVVNNIFGGSISSRLFQKIREEKGLVYSIYSSQTLYRKCGELGIFASMSTENLQDVYNLIKKEI
ENIRENYLTEKEISESKEQLKGNYILDLESTSSRMMSTGKSMLLSKKVKTTDEILECINNVNINSIKKVVDKVFNIENIG
TCIVGRDVEKILHLD

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=406, Percent_Identity=28.5714285714286, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI46593007, Length=403, Percent_Identity=23.3250620347395, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI24308013, Length=428, Percent_Identity=25.4672897196262, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI155969707, Length=235, Percent_Identity=25.1063829787234, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI50592988, Length=401, Percent_Identity=18.7032418952618, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI1787770, Length=207, Percent_Identity=26.0869565217391, Blast_Score=79, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71999683, Length=411, Percent_Identity=26.2773722627737, Blast_Score=186, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17553678, Length=418, Percent_Identity=23.9234449760766, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17510601, Length=427, Percent_Identity=19.672131147541, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323192, Length=400, Percent_Identity=29.5, Blast_Score=191, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6321813, Length=422, Percent_Identity=22.9857819905213, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI21357875, Length=396, Percent_Identity=27.2727272727273, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24646943, Length=396, Percent_Identity=27.2727272727273, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI19921772, Length=431, Percent_Identity=23.4338747099768, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24665395, Length=401, Percent_Identity=20.6982543640898, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 47280; Mature: 47280

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKTKILENGLTIIGEEIPYLKSITLGIWINAGSRIEEAQVSGTSHFIEHMMFKGTKNRT
CCCCHHHHCCCEEECCCCCHHHEEEEEEEECCCCCCHHHHHCCHHHHHHHHHHCCCCCCH
SKEIASSIDNLGGQINAFTSKECTCYYVKLIDEHIDTGIDVLSDMILNSKFDKNDIDKER
HHHHHHHHHHCCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
LIILEELKMYEDSPDDLSYDLLVENIYANDGLGMNIIGTKESLYNITRESMLEYLNKYYI
HHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCC
PNNAVISIAGNFNFDDMVEKIKSKFGHWEKKNLSIDISEAKFNPCFISKNKDTEQVNLAM
CCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEECCCCCHHHHHHH
CLKGIPFENDEEVYSMAVVNNIFGGSISSRLFQKIREEKGLVYSIYSSQTLYRKCGELGI
HHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCE
FASMSTENLQDVYNLIKKEIENIRENYLTEKEISESKEQLKGNYILDLESTSSRMMSTGK
EEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCHHHHHHHHHH
SMLLSKKVKTTDEILECINNVNINSIKKVVDKVFNIENIGTCIVGRDVEKILHLD
HHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEECCCHHHHHCCC
>Mature Secondary Structure
MYKTKILENGLTIIGEEIPYLKSITLGIWINAGSRIEEAQVSGTSHFIEHMMFKGTKNRT
CCCCHHHHCCCEEECCCCCHHHEEEEEEEECCCCCCHHHHHCCHHHHHHHHHHCCCCCCH
SKEIASSIDNLGGQINAFTSKECTCYYVKLIDEHIDTGIDVLSDMILNSKFDKNDIDKER
HHHHHHHHHHCCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
LIILEELKMYEDSPDDLSYDLLVENIYANDGLGMNIIGTKESLYNITRESMLEYLNKYYI
HHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCC
PNNAVISIAGNFNFDDMVEKIKSKFGHWEKKNLSIDISEAKFNPCFISKNKDTEQVNLAM
CCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEECCCCCHHHHHHH
CLKGIPFENDEEVYSMAVVNNIFGGSISSRLFQKIREEKGLVYSIYSSQTLYRKCGELGI
HHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCE
FASMSTENLQDVYNLIKKEIENIRENYLTEKEISESKEQLKGNYILDLESTSSRMMSTGK
EEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCHHHHHHHHHH
SMLLSKKVKTTDEILECINNVNINSIKKVVDKVFNIENIGTCIVGRDVEKILHLD
HHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEECCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 8098035 [H]