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The map label for this gene is nrnA [H]

Identifier: 126698910

GI number: 126698910

Start: 1520876

End: 1521544

Strand: Direct

Name: nrnA [H]

Synonym: CD1311

Alternate gene names: 126698910

Gene position: 1520876-1521544 (Clockwise)

Preceding gene: 126698909

Following gene: 126698911

Centisome position: 35.45

GC content: 26.61

Gene sequence:

>2859_bases
ATGATGAATAATATGGATAGTATTATAAACTATATTTATGAGGGTGACTATTTTATAGTTACCTCTCATATCAGTCCAGA
TGGAGACAATATTGGTTCTACACTTTCAATGTATTATACATTGAAGAATTTAGGAAAAAATGTATATTATGTACTTGATG
ATGAAGCTCCATTAAATTTAAGGTTTTTGGTTGAAGGTGTAAAAATCTATAAGTCTAATGAATTTAATATGAAGAACTAT
TCTCTAATTGCACTTGATTGTGGAGATAAGATGAGAATATGTGTGAGTGATGAAATCAAAAATAATGCATCAAAATTAAT
CTGTATTGACCATCATGCTAGTAATGATTCATATGGAGATTTAAATTATGTAGATATTGATGCATCTTCTACATGTGAAT
TAGTTTATAATTTATTAGTTAGATTTCAGCAAATAAAAGATATTAATATTATAAATGAAGATATAGCAACATGTTTATAT
ACAGGTCTTGTAACTGATACTGGAAACTTTTCGTATTCAAATGTACATGCAAGTAGCTTTGAAATGGCAAAAAATTTACT
TGTTTTAGGTGCACAAAAAAATACTATAATACAAAATATATATCAAAGCAATTCTTCTGGTTATTACAAATTATTAGGAG
AAGCTCTAAAGGGTTTGGAGATATTTGATTAAAAAATAGTTACGCACACTCGTGACTTTAGTCATGAGTTAGTAGCTAAA
ATAGTCAGCATATAGGGAAACTTATATGTAGAGATAGGATAAAACCTATCCAATACTACTTGAATTGCTGGAAACCCCTA
AAGCTAACCAAACTAAAACATAAGGATGAAATAAACCTAAGTGTGAAAGTTACGAAAGTAGAAAAAATTGGTTAGATGGT
ATAAGGTTAAACCCTAAGTACTTTAAAATGGGCAATCAGCAGGTAAGCTCCGAATAGGAGAAACTTCAACGACTATTCCT
CTTGAGGGAAGTACACTACAAGCTATTGGTAGTGGAAGTGGGTAGACCTTAACGGATAATGCCGAAGGATAAGATATAGT
CTGTGCTTGCATGAAAGTGTAAGAAGTTCATAAGAGAACTGCATAGGTAGTAGCGAACTTATGTGAACGACAACCTCAAA
AATGATAAAAGTTAAGACTTACGGTTCTTAAATATGTTATTTAAAATTAAATATAAAACCTTCTAAATAATTGTTTTAAA
TAATTACATTTGTTAATATTATGATAGGTGATTAATAAATTGTTCACCACAGCATTATATAATATATTAAATATGATAAA
ATCATTAAAAAGTGTATCAAAAAACAATTAACGTGAGGTGATAGCAGTGAAAAAAGCCTATAAGTTTAGAATGTATCCAA
ATAAAAAACAACAAGAGTTAATTAACAAAACTTTTGGATGTTGTAGATTTGTATATAATAAATATCTTGCTAAAAGAATA
GATGTTTATAAAAGCGATAAAGAAACTTTTACTTATAAACAGTGTAGTTCTGATTTGACCAATTTAAAAAAAGAATTAAA
ATGGCTTAAGGAACCTGACAAATTTTCACTACAAAACGCCTTAAAAGATTTAGATAATGCATATAAAAAATTCTTTAAAG
AAAAGGCAGGATTTCCTAAATTTAAATCAAAGAAAATTAATAGATTTTCATATAAAACTAACTTTACAAATGGAAACATT
ATGTATTGTGGTCAATATATAAAACTACCTAAACTTGGTATGGTTAAGATAAGGGATAAACAAGTACCTCAAGGTAGAAT
ACTTAATGCTACTATATCTAAAGAACCAAGTGGTAGATATTATGTATCATTATGCTGTACTGATGTAGATATTGAAGTAT
TTGAAAATACTAATAATCATATAGGTTTAGATTTAGGAATTAAAGAATTTTGTATCTCAAGTTGTGGAGACTTTATAGAA
AATCCTAAGTATCTTAAGAAGTCATTAAACAAGCTTGCTAAATTACAAAGAGAATTATCGAGAAAAACAATCGGTAGTTT
AAATAGAAATAAAGCAAGATTAAAAGTTGCAGGACTTCAAGAACATATAGCTAATCAAAGAAATGATTTTCTACAAAAAC
TATCTACTAAATTAATAAAAGAGAATGATATTATTTGCATAGAAGATTTACAAGTAAAGAATATGATTAGAAATCGTAAA
CTATCTCGCTTAATTTCAGATGTATCATGGTCAGAATTTATTCGTCAATTAGAATACAAGGCTAATTGGTATGGTAGACA
AATTGTAAAGGTAGGTAAATTCTTTGCAAGTTCACAAATATGCAATAAATGTGGGTATAAAAACGAGGAAATTAAGGACT
TAAATATAAGAGAATGGATTTGTCCTAGTTGTAATGAAACTCACGATAGAGATATAAATGCAAGTATAAATATATTAAAA
GAAGGATTAAGACTAATAACGATTCAAAATAAATAACTTATGTAAGAACCGTAGGAACTACGGGGATAGCCTGTGGAGAA
TTAGTAAGACATATTTTAATATGCAAAATTCTGTGAAGCAGGAACCCTGTGACTTTAGTCATGGGAGGTTCAGTCAAAGG
TATCTAGTATAGTTTTAACTCAAGACATGATGAATAGAAATAATATTAGCTTTAATGATGTTGATGGAATAACAACATAT
ACAAGAGACATAAAAGGTATAGAAGTTGGAATTTTATTTAAAGAGAAAAAACAAAATGAAATTAAAGTGAGTTTTAGGTC
AAAAAATTATGTTGATGTAAGTGAAATAGCCAAGTTATTTGGTGGTGGTGGTCATGTAAGGGCTGCTGGATGTACTATTA
GAGATAGTATTGATAATGCAAAGAAAATGGTACTAGAGGCAGTGTTAAAATCAATTTAA

Upstream 100 bases:

>100_bases
GTATTTAAACTTGATGATTCAATAGAAAAAGGAATGTATATGGATAGCCTTATAAAAAGAGTTAATGAAAAAAATGCTCA
ACAAAATGAGGATGAAAATT

Downstream 100 bases:

>100_bases
GGTGACAGTAAAATGAATAAGATTATAAGTATATTGAAACCCACAGGTATGACATCTCATGATGTTGTAAGTAGAGTGAG
AAAGATTTTAAATATAAAAA

Product: RNA-binding protein

Products: NA

Alternate protein names: 3'(2'),5'-bisphosphate nucleotidase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; nanoRNAse [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>324_residues
MMNNMDSIINYIYEGDYFIVTSHISPDGDNIGSTLSMYYTLKNLGKNVYYVLDDEAPLNLRFLVEGVKIYKSNEFNMKNY
SLIALDCGDKMRICVSDEIKNNASKLICIDHHASNDSYGDLNYVDIDASSTCELVYNLLVRFQQIKDINIINEDIATCLY
TGLVTDTGNFSYSNVHASSFEMAKNLLVLGAQKNTIIQNIYQSNSSGYYKLLGEALKGLEIFDSKVSSIVLTQDMMNRNN
ISFNDVDGITTYTRDIKGIEVGILFKEKKQNEIKVSFRSKNYVDVSEIAKLFGGGGHVRAAGCTIRDSIDNAKKMVLEAV
LKSI

Sequences:

>Translated_223_residues
MMNNMDSIINYIYEGDYFIVTSHISPDGDNIGSTLSMYYTLKNLGKNVYYVLDDEAPLNLRFLVEGVKIYKSNEFNMKNY
SLIALDCGDKMRICVSDEIKNNASKLICIDHHASNDSYGDLNYVDIDASSTCELVYNLLVRFQQIKDINIINEDIATCLY
TGLVTDTGNFSYSNVHASSFEMAKNLLVLGAQKNTIIQNIYQSNSSGYYKLLGEALKGLEIFD
>Mature_223_residues
MMNNMDSIINYIYEGDYFIVTSHISPDGDNIGSTLSMYYTLKNLGKNVYYVLDDEAPLNLRFLVEGVKIYKSNEFNMKNY
SLIALDCGDKMRICVSDEIKNNASKLICIDHHASNDSYGDLNYVDIDASSTCELVYNLLVRFQQIKDINIINEDIATCLY
TGLVTDTGNFSYSNVHASSFEMAKNLLVLGAQKNTIIQNIYQSNSSGYYKLLGEALKGLEIFD

Specific function: Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA oligonucleotides with a length of 5 nucleotides and shorter. Converts 3'(2')- phosphoadenosine 5'-phosphate (PAP) to AMP [H]

COG id: COG0618

COG function: function code R; Exopolyphosphatase-related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003156
- InterPro:   IPR001667 [H]

Pfam domain/function: PF01368 DHH; PF02272 DHHA1 [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 25148; Mature: 25148

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNNMDSIINYIYEGDYFIVTSHISPDGDNIGSTLSMYYTLKNLGKNVYYVLDDEAPLNL
CCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEE
RFLVEGVKIYKSNEFNMKNYSLIALDCGDKMRICVSDEIKNNASKLICIDHHASNDSYGD
EEEEEEEEEEECCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCC
LNYVDIDASSTCELVYNLLVRFQQIKDINIINEDIATCLYTGLVTDTGNFSYSNVHASSF
CEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEECCCCCEECCEEHHHH
EMAKNLLVLGAQKNTIIQNIYQSNSSGYYKLLGEALKGLEIFD
HHHCCEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MMNNMDSIINYIYEGDYFIVTSHISPDGDNIGSTLSMYYTLKNLGKNVYYVLDDEAPLNL
CCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEE
RFLVEGVKIYKSNEFNMKNYSLIALDCGDKMRICVSDEIKNNASKLICIDHHASNDSYGD
EEEEEEEEEEECCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCC
LNYVDIDASSTCELVYNLLVRFQQIKDINIINEDIATCLYTGLVTDTGNFSYSNVHASSF
CEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEECCCCCEECCEEHHHH
EMAKNLLVLGAQKNTIIQNIYQSNSSGYYKLLGEALKGLEIFD
HHHCCEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]