Click here to switch to the map view.

The map label for this gene is nusA [H]

Identifier: 126698905

GI number: 126698905

Start: 1516758

End: 1517912

Strand: Direct

Name: nusA [H]

Synonym: CD1307

Alternate gene names: 126698905

Gene position: 1516758-1517912 (Clockwise)

Preceding gene: 126698904

Following gene: 126698906

Centisome position: 35.35

GC content: 31.77

Gene sequence:

>1155_bases
ATGAATCATGAATTTATGGAAGCATTAGATGAATTAGTAGTTGACAGAGGTATAGATAAAGAAATACTTATAGATACTAT
AGAACAAGCTCTTTTAACTGCATACAAGAAAAACTTTGGTTCAGCACAAAATGTTAGAGTTGAATTTGATAGAGACAAGG
GAGATATAAAAGTATTTTCTCAAAGAGTTGTTGTTGATGAATCAGATTTATATGATACTTTCTTAGAAATAGAGTTAGCA
GATGCTAGAGAGATAAACCCTAATTATGAATTAGGTGATATTATAGAACATGAAGTTACACCTAAAAACTTTGGAAGAAT
TGCAGCTCAAACAGCAAAGCAAGTAGTTGTTCAAAGAATAAGGGAAGCTGAGAGAGAAATAGTGTATAATGAATTTATAG
AAAAAGAAAATGAAATAGTTACAGGAGAGGTTGCTAGAGCAAATAAAAATGTTGTTTATGTAAATCTTGGAAGAATAGAA
GGTATAATGACTCAAAGTGAACAAATACCATTTGAGAATTATAAAGCAGGTCAAAAAATAAAATTCTATATACTTGAAGT
TAAAAAGACTAACAAAGGACCTCAAATAGTTGTATCAAGAAGTCATCCGGGTCTAGTAAAGAGATTGTTTGAAGAAGAAG
TTCCTGAAATATATGAAGGAATAGTTCAAATAAAATCTGTAGCAAGAGAAGCAGGGTCAAGAACTAAAATGGCAGTAAGA
TCTATAGATGAAAAAATAGACCCAATTGGAGCTTGTGTTGGACCAAAAGGACTTAGAGTAAAAAATATAGTGGATGAACT
TGGCGATGAGAAAATAGATATAATAAAATATAGTGAAGACCCAGCAGAGTTTATATCAGCAGCACTTAGCCCATCAAAGG
TTGTTAGAGTAGATATAGATGAAGATGAAAAGTCTGCCTTAGTAATCGTTCCAGATTATCAGTTATCGCTTGCTATAGGT
AAAGAAGGTCAAAATGCAAGACTAGCAGCAAAATTGACTAACTGGAAAATAGATATTAAGAGCGAATCTCAAGCAGAACA
AGAAATGTTAAATCTTGAAAATTCCAAAGAAATAGAAGCTGAGGATGTTGAAGCTGAATTTATAGACCAAGAAGAGTTAG
ATACTTCAGAGGATAATTTTAGTGAAGAAGAGTAA

Upstream 100 bases:

>100_bases
TTGCAAATGGTAAGGAAATGGAATTTAATAGAAAAGATGTTGCTATTGTCAGATTAGCAATAAAGTTTTAGTGGTATATT
AAATAGGGAGGATATAAAAA

Downstream 100 bases:

>100_bases
GGAGGGATGATTTTGAAAAAAGTAAAAAAAGTGCCTCAAAGAAAATGCATAGCATGTCAAGATAGAGACTCTAAAAAAGA
GCTTATAAGAATAGTTAAAA

Product: transcription elongation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MNHEFMEALDELVVDRGIDKEILIDTIEQALLTAYKKNFGSAQNVRVEFDRDKGDIKVFSQRVVVDESDLYDTFLEIELA
DAREINPNYELGDIIEHEVTPKNFGRIAAQTAKQVVVQRIREAEREIVYNEFIEKENEIVTGEVARANKNVVYVNLGRIE
GIMTQSEQIPFENYKAGQKIKFYILEVKKTNKGPQIVVSRSHPGLVKRLFEEEVPEIYEGIVQIKSVAREAGSRTKMAVR
SIDEKIDPIGACVGPKGLRVKNIVDELGDEKIDIIKYSEDPAEFISAALSPSKVVRVDIDEDEKSALVIVPDYQLSLAIG
KEGQNARLAAKLTNWKIDIKSESQAEQEMLNLENSKEIEAEDVEAEFIDQEELDTSEDNFSEEE

Sequences:

>Translated_384_residues
MNHEFMEALDELVVDRGIDKEILIDTIEQALLTAYKKNFGSAQNVRVEFDRDKGDIKVFSQRVVVDESDLYDTFLEIELA
DAREINPNYELGDIIEHEVTPKNFGRIAAQTAKQVVVQRIREAEREIVYNEFIEKENEIVTGEVARANKNVVYVNLGRIE
GIMTQSEQIPFENYKAGQKIKFYILEVKKTNKGPQIVVSRSHPGLVKRLFEEEVPEIYEGIVQIKSVAREAGSRTKMAVR
SIDEKIDPIGACVGPKGLRVKNIVDELGDEKIDIIKYSEDPAEFISAALSPSKVVRVDIDEDEKSALVIVPDYQLSLAIG
KEGQNARLAAKLTNWKIDIKSESQAEQEMLNLENSKEIEAEDVEAEFIDQEELDTSEDNFSEEE
>Mature_384_residues
MNHEFMEALDELVVDRGIDKEILIDTIEQALLTAYKKNFGSAQNVRVEFDRDKGDIKVFSQRVVVDESDLYDTFLEIELA
DAREINPNYELGDIIEHEVTPKNFGRIAAQTAKQVVVQRIREAEREIVYNEFIEKENEIVTGEVARANKNVVYVNLGRIE
GIMTQSEQIPFENYKAGQKIKFYILEVKKTNKGPQIVVSRSHPGLVKRLFEEEVPEIYEGIVQIKSVAREAGSRTKMAVR
SIDEKIDPIGACVGPKGLRVKNIVDELGDEKIDIIKYSEDPAEFISAALSPSKVVRVDIDEDEKSALVIVPDYQLSLAIG
KEGQNARLAAKLTNWKIDIKSESQAEQEMLNLENSKEIEAEDVEAEFIDQEELDTSEDNFSEEE

Specific function: Participates in both the termination and antitermination of transcription. Interacts with RNA polymerase and binds RNA [H]

COG id: COG0195

COG function: function code K; Transcription elongation factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Escherichia coli, GI1789560, Length=353, Percent_Identity=38.2436260623229, Blast_Score=261, Evalue=5e-71,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1612 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004087
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004088
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013735
- InterPro:   IPR010213 [H]

Pfam domain/function: PF08529 NusA_N; PF00575 S1 [H]

EC number: NA

Molecular weight: Translated: 43512; Mature: 43512

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: PS50084 KH_TYPE_1 ; PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHEFMEALDELVVDRGIDKEILIDTIEQALLTAYKKNFGSAQNVRVEFDRDKGDIKVFS
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEE
QRVVVDESDLYDTFLEIELADAREINPNYELGDIIEHEVTPKNFGRIAAQTAKQVVVQRI
EEEEECCCHHHHHEEEEEECCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
REAEREIVYNEFIEKENEIVTGEVARANKNVVYVNLGRIEGIMTQSEQIPFENYKAGQKI
HHHHHHHHHHHHHHCCCCEEECCHHCCCCCEEEEECCCCHHHHCCCCCCCCCCCCCCCEE
KFYILEVKKTNKGPQIVVSRSHPGLVKRLFEEEVPEIYEGIVQIKSVAREAGSRTKMAVR
EEEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
SIDEKIDPIGACVGPKGLRVKNIVDELGDEKIDIIKYSEDPAEFISAALSPSKVVRVDID
HHHHHCCCHHHCCCCCCCCHHHHHHHHCCCEEEEEEECCCHHHHHHHHCCCCEEEEEECC
EDEKSALVIVPDYQLSLAIGKEGQNARLAAKLTNWKIDIKSESQAEQEMLNLENSKEIEA
CCCCCEEEEECCCEEEEEECCCCCCCEEEEEEECEEEEECCCHHHHHHHHCCCCCCCCCH
EDVEAEFIDQEELDTSEDNFSEEE
HCCHHHHCCHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNHEFMEALDELVVDRGIDKEILIDTIEQALLTAYKKNFGSAQNVRVEFDRDKGDIKVFS
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEE
QRVVVDESDLYDTFLEIELADAREINPNYELGDIIEHEVTPKNFGRIAAQTAKQVVVQRI
EEEEECCCHHHHHEEEEEECCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
REAEREIVYNEFIEKENEIVTGEVARANKNVVYVNLGRIEGIMTQSEQIPFENYKAGQKI
HHHHHHHHHHHHHHCCCCEEECCHHCCCCCEEEEECCCCHHHHCCCCCCCCCCCCCCCEE
KFYILEVKKTNKGPQIVVSRSHPGLVKRLFEEEVPEIYEGIVQIKSVAREAGSRTKMAVR
EEEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
SIDEKIDPIGACVGPKGLRVKNIVDELGDEKIDIIKYSEDPAEFISAALSPSKVVRVDID
HHHHHCCCHHHCCCCCCCCHHHHHHHHCCCEEEEEEECCCHHHHHHHHCCCCEEEEEECC
EDEKSALVIVPDYQLSLAIGKEGQNARLAAKLTNWKIDIKSESQAEQEMLNLENSKEIEA
CCCCCEEEEECCCEEEEEECCCCCCCEEEEEEECEEEEECCCHHHHHHHHCCCCCCCCCH
EDVEAEFIDQEELDTSEDNFSEEE
HCCHHHHCCHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]