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The map label for this gene is fur [H]

Identifier: 126698884

GI number: 126698884

Start: 1495161

End: 1495619

Strand: Direct

Name: fur [H]

Synonym: CD1287

Alternate gene names: 126698884

Gene position: 1495161-1495619 (Clockwise)

Preceding gene: 126698883

Following gene: 126698886

Centisome position: 34.85

GC content: 30.07

Gene sequence:

>459_bases
ATGGCAAATACAATGGATTTATTAAAAGACAAGTTAAAAGAAACTGGTTTTAAGATTACGCCACAAAGAAGAGCAATAGT
TGAAATATTGCTTAAACATGACCATTCACATCTAAGTAGTGAGGAAATCTATGATTTAGTTAGGGTTGACTGTCCTGAAA
TAGGCTTAGCTACTGTATATAGAACAATGCAGCTATTGGATGAAATAGGATTAATATCAAAACTAAACTTAGACGATGGA
TGTATAAGATATGAGATTAGTCTACATAAAGAAGACTGTCATAATCATCATCATCTTATTTGTAAAAATTGTGGAAAGAT
AATGGAAGCTAAAGAAGACCTTTTAGACAATATAGAAAAAGAGATACAATCATTGTACAAATTTAAAATACTTGATCATG
ATGTTAAATTTTATGGACTATGTGACGAGTGTAATGGAGTAAGCGATTCAGAAGAATAA

Upstream 100 bases:

>100_bases
GAATAAATTAAATTTATTTAAATGTCTTGACAAAAAATGAATTATCAATTACAATATTATTTAATAAAGATTATCAATTG
AAAATAGTAAGGGTGATGTT

Downstream 100 bases:

>100_bases
ACTTCTATTGCTTAATGTCGATGGAAGAATAGTATAGAACTTTTATATTCTATGCTATTCTTCCATTTTTTATTATAAAC
CATCTATAAAATGCAAATAT

Product: ferric uptake regulation protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 152; Mature: 151

Protein sequence:

>152_residues
MANTMDLLKDKLKETGFKITPQRRAIVEILLKHDHSHLSSEEIYDLVRVDCPEIGLATVYRTMQLLDEIGLISKLNLDDG
CIRYEISLHKEDCHNHHHLICKNCGKIMEAKEDLLDNIEKEIQSLYKFKILDHDVKFYGLCDECNGVSDSEE

Sequences:

>Translated_152_residues
MANTMDLLKDKLKETGFKITPQRRAIVEILLKHDHSHLSSEEIYDLVRVDCPEIGLATVYRTMQLLDEIGLISKLNLDDG
CIRYEISLHKEDCHNHHHLICKNCGKIMEAKEDLLDNIEKEIQSLYKFKILDHDVKFYGLCDECNGVSDSEE
>Mature_151_residues
ANTMDLLKDKLKETGFKITPQRRAIVEILLKHDHSHLSSEEIYDLVRVDCPEIGLATVYRTMQLLDEIGLISKLNLDDGC
IRYEISLHKEDCHNHHHLICKNCGKIMEAKEDLLDNIEKEIQSLYKFKILDHDVKFYGLCDECNGVSDSEE

Specific function: Iron uptake repressor. Acts on the transcription of ferri-siderophore uptake genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=132, Percent_Identity=34.8484848484849, Blast_Score=91, Evalue=2e-20,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17586; Mature: 17455

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANTMDLLKDKLKETGFKITPQRRAIVEILLKHDHSHLSSEEIYDLVRVDCPEIGLATVY
CCCHHHHHHHHHHHCCCEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHH
RTMQLLDEIGLISKLNLDDGCIRYEISLHKEDCHNHHHLICKNCGKIMEAKEDLLDNIEK
HHHHHHHHHCCHHCCCCCCCEEEEEEEECHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
EIQSLYKFKILDHDVKFYGLCDECNGVSDSEE
HHHHHHHHHHHCCCCCEEEECHHCCCCCCCCC
>Mature Secondary Structure 
ANTMDLLKDKLKETGFKITPQRRAIVEILLKHDHSHLSSEEIYDLVRVDCPEIGLATVY
CCHHHHHHHHHHHCCCEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHH
RTMQLLDEIGLISKLNLDDGCIRYEISLHKEDCHNHHHLICKNCGKIMEAKEDLLDNIEK
HHHHHHHHHCCHHCCCCCCCEEEEEEEECHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
EIQSLYKFKILDHDVKFYGLCDECNGVSDSEE
HHHHHHHHHHHCCCCCEEEECHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9701813 [H]