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The map label for this gene is ftsY [H]

Identifier: 126698847

GI number: 126698847

Start: 1454361

End: 1455641

Strand: Direct

Name: ftsY [H]

Synonym: CD1251

Alternate gene names: 126698847

Gene position: 1454361-1455641 (Clockwise)

Preceding gene: 126698846

Following gene: 126698848

Centisome position: 33.9

GC content: 31.07

Gene sequence:

>1281_bases
GTGTTAAAAAAATTATTTGGTTTTGGAAAAGACAAGGAAAAGGAAATAGAAAAAAAAGATGCTGAAGAAGAAATAGAAGT
TGAAGACAGTGTTGATAATTTAGAAAACTTGGAAGAAACTATTTTTTCAGGACTTGAAGAAGAAGTGATAGATAAAGTGG
AAGATGTTGAAGAAAAAAATGAGGAAAGTGTCAATGATGAAGGCACTGAAGAAATCGAAAACTTTGAAAAAATAGAAGTT
GAGATGGATAGTAATGGAAAAGAAGTAGAAAATATTTCAAATAATGATTCTCAAGAAGAGATAATCGAAGAATTAGAAAA
TTATGATGAAATTGAGTCTAAAGAGATAGAAGATAAAGAAGATAAGAAAGTTAACTTGTTTGAAAGACTAAAACAAGGAT
TGACAAAAGCAAAGCAAGGAATAACTGATAGAATAGATGAAGTTTTAAAATCATATACAAAGATAGATGAAGAATTACTT
GAAGATTTAGAGGAAATTTTAATAACAGCAGATGTTGGTGTAAATACAACTATGGATATAATTGAAAGACTAAGAGATAA
AATAAAGCAAAAAGGTATTACTGAACCAATAAAGGTAAGAGAAGAACTTAAATCTATAGTTGAAGATATTCTTACAAATG
AAAACTCTACACTAGATATAGAACCAGCACCATGTATAATATTAATGGTGGGTGTAAATGGGGTCGGTAAGACTACTACA
ATAGGTAAACTAGCAAATAGATACAAAAAAGATGGTAAAAAAGTTTTATTAGCAGCAGCAGATACATTTAGAGCAGCAGC
GACAGAGCAATTAGAAATTTGGGCAAATAGAACCAATGTAGACATAATAAAACATCAAGAGGGAGCAGACCCTGGAGCTG
TAGTATTTGATGCTATAAAAGCTGCAAAAGCTAGAAAAACAGATGTATTAATATGTGATACAGCAGGAAGATTACACAAT
AAGGCTAATCTTATGAATGAACTTGGAAAAGTATTTAAAATAGTAGATAGAGAATTTCCAGAAGCAAAACGTGAAGTACT
TCTTGTGGTGGATGCTACAACAGGTCAAAATGCAGTTGTTCAAGCAAAGACATTTAAAGAAGTTGCAGATATAACAGGTA
TAGTACTTACAAAACTTGATGGAACTGCAAAAGGTGGAGTAGTCCTTGCAGTAAAATCAGAAGTAGATGTACCTGTAAAA
CTTATTGGAGTTGGAGAAAGTGTAGAAGACCTACAAGATTTCAATGCAAAATCATTTTCAGATGCATTATTTGGTAACTA
A

Upstream 100 bases:

>100_bases
TGCAAGAAAAAGCCATTTCAAAAGTTATTAGTTTAAAATTAAAAGAAGCTCAGGAAATAACAGATATTATATAACTTAGA
TTGACATAGGAGGAATAACA

Downstream 100 bases:

>100_bases
TGTTCTTTTAAAAATAATGGTTGACAAGAGTGTTGTTATGATATAAAATACAATAGTGTAAAGTAAATAACCTTTACAGT
ATACTGCTAGGAAGTGTAAG

Product: signal recognition particle

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MLKKLFGFGKDKEKEIEKKDAEEEIEVEDSVDNLENLEETIFSGLEEEVIDKVEDVEEKNEESVNDEGTEEIENFEKIEV
EMDSNGKEVENISNNDSQEEIIEELENYDEIESKEIEDKEDKKVNLFERLKQGLTKAKQGITDRIDEVLKSYTKIDEELL
EDLEEILITADVGVNTTMDIIERLRDKIKQKGITEPIKVREELKSIVEDILTNENSTLDIEPAPCIILMVGVNGVGKTTT
IGKLANRYKKDGKKVLLAAADTFRAAATEQLEIWANRTNVDIIKHQEGADPGAVVFDAIKAAKARKTDVLICDTAGRLHN
KANLMNELGKVFKIVDREFPEAKREVLLVVDATTGQNAVVQAKTFKEVADITGIVLTKLDGTAKGGVVLAVKSEVDVPVK
LIGVGESVEDLQDFNAKSFSDALFGN

Sequences:

>Translated_426_residues
MLKKLFGFGKDKEKEIEKKDAEEEIEVEDSVDNLENLEETIFSGLEEEVIDKVEDVEEKNEESVNDEGTEEIENFEKIEV
EMDSNGKEVENISNNDSQEEIIEELENYDEIESKEIEDKEDKKVNLFERLKQGLTKAKQGITDRIDEVLKSYTKIDEELL
EDLEEILITADVGVNTTMDIIERLRDKIKQKGITEPIKVREELKSIVEDILTNENSTLDIEPAPCIILMVGVNGVGKTTT
IGKLANRYKKDGKKVLLAAADTFRAAATEQLEIWANRTNVDIIKHQEGADPGAVVFDAIKAAKARKTDVLICDTAGRLHN
KANLMNELGKVFKIVDREFPEAKREVLLVVDATTGQNAVVQAKTFKEVADITGIVLTKLDGTAKGGVVLAVKSEVDVPVK
LIGVGESVEDLQDFNAKSFSDALFGN
>Mature_426_residues
MLKKLFGFGKDKEKEIEKKDAEEEIEVEDSVDNLENLEETIFSGLEEEVIDKVEDVEEKNEESVNDEGTEEIENFEKIEV
EMDSNGKEVENISNNDSQEEIIEELENYDEIESKEIEDKEDKKVNLFERLKQGLTKAKQGITDRIDEVLKSYTKIDEELL
EDLEEILITADVGVNTTMDIIERLRDKIKQKGITEPIKVREELKSIVEDILTNENSTLDIEPAPCIILMVGVNGVGKTTT
IGKLANRYKKDGKKVLLAAADTFRAAATEQLEIWANRTNVDIIKHQEGADPGAVVFDAIKAAKARKTDVLICDTAGRLHN
KANLMNELGKVFKIVDREFPEAKREVLLVVDATTGQNAVVQAKTFKEVADITGIVLTKLDGTAKGGVVLAVKSEVDVPVK
LIGVGESVEDLQDFNAKSFSDALFGN

Specific function: Required for normal cell growth and morphogenesis; translocation of at least 1 protein is impaired in its absence [H]

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=287, Percent_Identity=29.2682926829268, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI226371618, Length=200, Percent_Identity=34, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI23308697, Length=307, Percent_Identity=30.2931596091205, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI295424842, Length=307, Percent_Identity=30.2931596091205, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI89061728, Length=136, Percent_Identity=30.8823529411765, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1789874, Length=327, Percent_Identity=48.0122324159021, Blast_Score=281, Evalue=5e-77,
Organism=Escherichia coli, GI1788963, Length=299, Percent_Identity=35.7859531772575, Blast_Score=168, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI17539958, Length=277, Percent_Identity=29.9638989169675, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI193206261, Length=296, Percent_Identity=30.0675675675676, Blast_Score=106, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6325345, Length=200, Percent_Identity=39, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320498, Length=223, Percent_Identity=29.1479820627803, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17647949, Length=294, Percent_Identity=30.952380952381, Blast_Score=128, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24641198, Length=308, Percent_Identity=29.5454545454545, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 47458; Mature: 47458

Theoretical pI: Translated: 4.22; Mature: 4.22

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKLFGFGKDKEKEIEKKDAEEEIEVEDSVDNLENLEETIFSGLEEEVIDKVEDVEEKN
CCHHHHCCCCCHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
EESVNDEGTEEIENFEKIEVEMDSNGKEVENISNNDSQEEIIEELENYDEIESKEIEDKE
HCCCCCCCHHHHHCHHEEEEEECCCCCHHHHCCCCCCHHHHHHHHHCCHHHHHHCCCCCC
DKKVNLFERLKQGLTKAKQGITDRIDEVLKSYTKIDEELLEDLEEILITADVGVNTTMDI
CCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
IERLRDKIKQKGITEPIKVREELKSIVEDILTNENSTLDIEPAPCIILMVGVNGVGKTTT
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEECCCCCCCCHH
IGKLANRYKKDGKKVLLAAADTFRAAATEQLEIWANRTNVDIIKHQEGADPGAVVFDAIK
HHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHEEECCCCCEEEECCCCCCCHHHHHHHHH
AAKARKTDVLICDTAGRLHNKANLMNELGKVFKIVDREFPEAKREVLLVVDATTGQNAVV
HHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEE
QAKTFKEVADITGIVLTKLDGTAKGGVVLAVKSEVDVPVKLIGVGESVEDLQDFNAKSFS
EHHHHHHHHHHHHHHEEECCCCCCCCEEEEEECCCCCCEEEEECCCCHHHHHHCCCCHHH
DALFGN
HHHCCC
>Mature Secondary Structure
MLKKLFGFGKDKEKEIEKKDAEEEIEVEDSVDNLENLEETIFSGLEEEVIDKVEDVEEKN
CCHHHHCCCCCHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
EESVNDEGTEEIENFEKIEVEMDSNGKEVENISNNDSQEEIIEELENYDEIESKEIEDKE
HCCCCCCCHHHHHCHHEEEEEECCCCCHHHHCCCCCCHHHHHHHHHCCHHHHHHCCCCCC
DKKVNLFERLKQGLTKAKQGITDRIDEVLKSYTKIDEELLEDLEEILITADVGVNTTMDI
CCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
IERLRDKIKQKGITEPIKVREELKSIVEDILTNENSTLDIEPAPCIILMVGVNGVGKTTT
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEECCCCCCCCHH
IGKLANRYKKDGKKVLLAAADTFRAAATEQLEIWANRTNVDIIKHQEGADPGAVVFDAIK
HHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHEEECCCCCEEEECCCCCCCHHHHHHHHH
AAKARKTDVLICDTAGRLHNKANLMNELGKVFKIVDREFPEAKREVLLVVDATTGQNAVV
HHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEE
QAKTFKEVADITGIVLTKLDGTAKGGVVLAVKSEVDVPVKLIGVGESVEDLQDFNAKSFS
EHHHHHHHHHHHHHHEEECCCCCCCCEEEEEECCCCCCEEEEECCCCHHHHHHCCCCHHH
DALFGN
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584053; 9384377; 8654983 [H]