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The map label for this gene is obg

Identifier: 126698759

GI number: 126698759

Start: 1362276

End: 1363553

Strand: Direct

Name: obg

Synonym: CD1164

Alternate gene names: 126698759

Gene position: 1362276-1363553 (Clockwise)

Preceding gene: 126698758

Following gene: 126698760

Centisome position: 31.75

GC content: 34.66

Gene sequence:

>1278_bases
TTGTTTATAGATAAGGCAAGAATATTTGTTAAGGCTGGAAATGGTGGAAATGGTTCGGTAGCATTTAGAAGAGAAAAATA
CGTTCCAGCTGGTGGTCCAGACGGTGGAGATGGTGGTCGTGGAGCAAGCATCATATTTGAAGTTGATTTGGGGCTTAGAA
CTCTAATGGACTTTAAGTACCAGAAAAAATATCAAGCTCAAAATGGTGGCGACGGAAGCAAAGGAAAAAGAGCTGGTAAA
AATGGAGAAAATTTAGTATTAAAAGTACCAGCAGGTACAGTAATAAGAGATGAGGCTACAGGTCTTGTATTAGCAGATTT
AAAAAAAGAAGGAGATACAGCTATAGTTGCAAAAGGTGGTATAGGTGGTAAAGGTAACCAACACTTTGCAAATGCAGTAA
GACAAGCTCCAGCTTTTGCAAAATCTGGTACAGATGGAGAAGAAAGATGGATAACTCTTGAACTTAAAATGATAGCAGAT
GTTGGTCTTTTAGGATTTCCAAATGTAGGTAAATCAACATTTCTATCAGTTGTAACTAAAGCTAAACCCAAAATTGCAAA
CTATCATTTTACAACACTTACACCAAATCTAGGTGTTGTTCAAACTAAGTTTGGAGATAGTTTTGTACTTGCAGATATAC
CTGGAATTATAGAGGGTGCTTCTGAAGGCATAGGATTAGGTCATGAGTTCTTAAGACATGTTGAGAGAACAAAGGTATTG
ATACATATTGTAGATATATCTGGATTAGAGGGAAGAGACCCTATTGAAGATTTTGACAAGATAAATGATGAGCTTAAATT
GTACAATGAAAAGCTTTCAAAGAGACCACAAGTTGTAGTTGCAAATAAATTTGATATATTAGAAGATGAGAGTAAGTTTG
AGAAGTTTAAGAGTGAATTAGAAGGCAGAGGATATACAGTATTTAAAATGTCAGCAGCAACTCGTCAAGGCATAGATGAA
GTAATAGCCTATGTTTCTAAAATGCTAAAAGAAGTAGAAGATGTGGAGCTAGTTTCAGAAGAAGAAATGTATAGACCAGA
ACTTGATATTGGTACTGAAGAAGAGTTAAGTATAGATATTGAAGATGGTGTGTATGTAGTTACAGGTAAAGCACTTAGAA
GAATAATGTATTCTGTAAATTTTGATGATATGGAATCCCTTCAATATTTCCAAAAAGCTATGGAGAGTCAAGGTGTTTTT
GATAGGCTTAGAGAAATGGGAATAGAAGATGGAGATGTGGTTAAAATTTATGAATTAGAATTTGAGTTTTACAATTAA

Upstream 100 bases:

>100_bases
AGGAGTGTTGAGGCACTCCTTTTTCTTATAATACTGATGAATTTATAATGGTATTTTTGGTAATGCTAATTAAAAGTTTT
TAATTAAGTAGGTGAAGAAT

Downstream 100 bases:

>100_bases
TTTAAATATAGATTATAGATAATTTAAGTATAGAATTATAGAGGTGAGAATATGTTAAAAGGAAAACAAAGGGCGTATTT
AAGATCTTTGGCAAATACTT

Product: Spo0B-associated GTP-binding protein

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MFIDKARIFVKAGNGGNGSVAFRREKYVPAGGPDGGDGGRGASIIFEVDLGLRTLMDFKYQKKYQAQNGGDGSKGKRAGK
NGENLVLKVPAGTVIRDEATGLVLADLKKEGDTAIVAKGGIGGKGNQHFANAVRQAPAFAKSGTDGEERWITLELKMIAD
VGLLGFPNVGKSTFLSVVTKAKPKIANYHFTTLTPNLGVVQTKFGDSFVLADIPGIIEGASEGIGLGHEFLRHVERTKVL
IHIVDISGLEGRDPIEDFDKINDELKLYNEKLSKRPQVVVANKFDILEDESKFEKFKSELEGRGYTVFKMSAATRQGIDE
VIAYVSKMLKEVEDVELVSEEEMYRPELDIGTEEELSIDIEDGVYVVTGKALRRIMYSVNFDDMESLQYFQKAMESQGVF
DRLREMGIEDGDVVKIYELEFEFYN

Sequences:

>Translated_425_residues
MFIDKARIFVKAGNGGNGSVAFRREKYVPAGGPDGGDGGRGASIIFEVDLGLRTLMDFKYQKKYQAQNGGDGSKGKRAGK
NGENLVLKVPAGTVIRDEATGLVLADLKKEGDTAIVAKGGIGGKGNQHFANAVRQAPAFAKSGTDGEERWITLELKMIAD
VGLLGFPNVGKSTFLSVVTKAKPKIANYHFTTLTPNLGVVQTKFGDSFVLADIPGIIEGASEGIGLGHEFLRHVERTKVL
IHIVDISGLEGRDPIEDFDKINDELKLYNEKLSKRPQVVVANKFDILEDESKFEKFKSELEGRGYTVFKMSAATRQGIDE
VIAYVSKMLKEVEDVELVSEEEMYRPELDIGTEEELSIDIEDGVYVVTGKALRRIMYSVNFDDMESLQYFQKAMESQGVF
DRLREMGIEDGDVVKIYELEFEFYN
>Mature_425_residues
MFIDKARIFVKAGNGGNGSVAFRREKYVPAGGPDGGDGGRGASIIFEVDLGLRTLMDFKYQKKYQAQNGGDGSKGKRAGK
NGENLVLKVPAGTVIRDEATGLVLADLKKEGDTAIVAKGGIGGKGNQHFANAVRQAPAFAKSGTDGEERWITLELKMIAD
VGLLGFPNVGKSTFLSVVTKAKPKIANYHFTTLTPNLGVVQTKFGDSFVLADIPGIIEGASEGIGLGHEFLRHVERTKVL
IHIVDISGLEGRDPIEDFDKINDELKLYNEKLSKRPQVVVANKFDILEDESKFEKFKSELEGRGYTVFKMSAATRQGIDE
VIAYVSKMLKEVEDVELVSEEEMYRPELDIGTEEELSIDIEDGVYVVTGKALRRIMYSVNFDDMESLQYFQKAMESQGVF
DRLREMGIEDGDVVKIYELEFEFYN

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=336, Percent_Identity=38.6904761904762, Blast_Score=199, Evalue=5e-51,
Organism=Homo sapiens, GI111955139, Length=359, Percent_Identity=34.2618384401114, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI111955063, Length=195, Percent_Identity=36.4102564102564, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI4557537, Length=87, Percent_Identity=47.1264367816092, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI58761500, Length=135, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI4758796, Length=118, Percent_Identity=41.5254237288136, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1789574, Length=348, Percent_Identity=45.4022988505747, Blast_Score=275, Evalue=4e-75,
Organism=Escherichia coli, GI1787454, Length=277, Percent_Identity=25.6317689530686, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17508313, Length=325, Percent_Identity=37.8461538461538, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17552324, Length=310, Percent_Identity=32.258064516129, Blast_Score=141, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17509631, Length=128, Percent_Identity=39.0625, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17555344, Length=118, Percent_Identity=39.8305084745763, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71981008, Length=87, Percent_Identity=42.5287356321839, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=177, Percent_Identity=43.5028248587571, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6321649, Length=149, Percent_Identity=32.2147651006711, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6319281, Length=126, Percent_Identity=38.0952380952381, Blast_Score=70, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6321612, Length=92, Percent_Identity=39.1304347826087, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI20129375, Length=328, Percent_Identity=38.4146341463415, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24585318, Length=371, Percent_Identity=32.3450134770889, Blast_Score=175, Evalue=5e-44,
Organism=Drosophila melanogaster, GI24640873, Length=134, Percent_Identity=34.3283582089552, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24640877, Length=134, Percent_Identity=34.3283582089552, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24640875, Length=134, Percent_Identity=34.3283582089552, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21356473, Length=117, Percent_Identity=41.8803418803419, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17981711, Length=118, Percent_Identity=40.6779661016949, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_CLOD6 (Q18B27)

Other databases:

- EMBL:   AM180355
- RefSeq:   YP_001087656.1
- ProteinModelPortal:   Q18B27
- SMR:   Q18B27
- STRING:   Q18B27
- GeneID:   4914992
- GenomeReviews:   AM180355_GR
- KEGG:   cdf:CD1164
- NMPDR:   fig|1496.1.peg.232
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   HFTTLVP
- ProtClustDB:   PRK12297
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR03595
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF102741 GTP-bd_prot_GTP1/OBG_C; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 46884; Mature: 46884

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIDKARIFVKAGNGGNGSVAFRREKYVPAGGPDGGDGGRGASIIFEVDLGLRTLMDFKY
CCCCCEEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHH
QKKYQAQNGGDGSKGKRAGKNGENLVLKVPAGTVIRDEATGLVLADLKKEGDTAIVAKGG
HHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEECCCCCEEEEECCCCCCEEEEEECC
IGGKGNQHFANAVRQAPAFAKSGTDGEERWITLELKMIADVGLLGFPNVGKSTFLSVVTK
CCCCCCHHHHHHHHHCCCHHCCCCCCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHH
AKPKIANYHFTTLTPNLGVVQTKFGDSFVLADIPGIIEGASEGIGLGHEFLRHVERTKVL
CCCCCCCEEEEEECCCCCEEEEECCCEEEEECCCHHHCCCCCCCCCHHHHHHHHHHCEEE
IHIVDISGLEGRDPIEDFDKINDELKLYNEKLSKRPQVVVANKFDILEDESKFEKFKSEL
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHH
EGRGYTVFKMSAATRQGIDEVIAYVSKMLKEVEDVELVSEEEMYRPELDIGTEEELSIDI
CCCCEEEEEECCHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCEEEEE
EDGVYVVTGKALRRIMYSVNFDDMESLQYFQKAMESQGVFDRLREMGIEDGDVVKIYELE
CCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEEEEE
FEFYN
EEECC
>Mature Secondary Structure
MFIDKARIFVKAGNGGNGSVAFRREKYVPAGGPDGGDGGRGASIIFEVDLGLRTLMDFKY
CCCCCEEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHH
QKKYQAQNGGDGSKGKRAGKNGENLVLKVPAGTVIRDEATGLVLADLKKEGDTAIVAKGG
HHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEECCCCCEEEEECCCCCCEEEEEECC
IGGKGNQHFANAVRQAPAFAKSGTDGEERWITLELKMIADVGLLGFPNVGKSTFLSVVTK
CCCCCCHHHHHHHHHCCCHHCCCCCCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHH
AKPKIANYHFTTLTPNLGVVQTKFGDSFVLADIPGIIEGASEGIGLGHEFLRHVERTKVL
CCCCCCCEEEEEECCCCCEEEEECCCEEEEECCCHHHCCCCCCCCCHHHHHHHHHHCEEE
IHIVDISGLEGRDPIEDFDKINDELKLYNEKLSKRPQVVVANKFDILEDESKFEKFKSEL
EEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHH
EGRGYTVFKMSAATRQGIDEVIAYVSKMLKEVEDVELVSEEEMYRPELDIGTEEELSIDI
CCCCEEEEEECCHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCEEEEE
EDGVYVVTGKALRRIMYSVNFDDMESLQYFQKAMESQGVFDRLREMGIEDGDVVKIYELE
CCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEEEEE
FEFYN
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA