Click here to switch to the map view.

The map label for this gene is yurK [H]

Identifier: 126698660

GI number: 126698660

Start: 1267223

End: 1267948

Strand: Direct

Name: yurK [H]

Synonym: CD1073

Alternate gene names: 126698660

Gene position: 1267223-1267948 (Clockwise)

Preceding gene: 126698659

Following gene: 126698661

Centisome position: 29.54

GC content: 27.41

Gene sequence:

>726_bases
ATGGATTTAGAAGTAAATTCCTTTGTTCCTTTATATCAACAACTATATGACAACATAAAAAAACAAATAGCATCTGGCAT
ATATAAACCAGGAGATAAACTTCCATCTGAAGGAGACTTATGTAAAGAATTTAATATAAGTCGTATAACTGTGAGAAATG
CACTTAATGAACTTGTAAAAGAAGATATATTATGTAAAAAACGTGGTAAAGGGACTTATGTAACAATACCAGAGAGAATA
GAAGCAACATGTGCAGGAAATAGTTTTACTAATTCTTGTCATCGTATTAATGCAAAACCAAGTACCAAAATAATCTCTGT
TTTAATAAAAAAAGCAGATAAGCAAGTAGCTGAAGCTTTAAGTATTGAACTAGAAGAGAAGGTAATATGTATTAAAAGAC
TTAGATTAATAGATGAAGTACCTGTTATTTTTGAAGTTGACTATTTTAGAATAGATTACATGTTTTTATTAAAAGAAGAA
TTAGAAGATAAATCTTTAATGGAGGTTATATCTAATAATATAAGCACATTACCTAAACGAGTAGAAAATATATTTGAAGT
AAAACATTCAAACAAAGAATATTCTGACCATCTTAAATGTGCAAGTAATATGCCACTATTGAAAGTAAGACAATCGGTGT
ATACAGAAAATAATGATGTCTTATATTACAATGAGCAATTTATAAGAAGTGATAAGTACAAATATGCAGTATCAGCAGAA
ATATAA

Upstream 100 bases:

>100_bases
CATCTTGTTATAATATGTAATAAAGAACTTGTTATATAATGTTATAAAAATGTTACATAGGGAGGTGAGCAAAATGGATG
AAAAGAGACAAAAAAAAGAA

Downstream 100 bases:

>100_bases
TCTATAATTTAGTAGGAGGATGAGTATGAAAAAGATAATATTAGCATCTCATGGAGACTTTTCAAAAGGGCTTTTAAATG
CAGTAAAAATGATAGTAGGA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MDLEVNSFVPLYQQLYDNIKKQIASGIYKPGDKLPSEGDLCKEFNISRITVRNALNELVKEDILCKKRGKGTYVTIPERI
EATCAGNSFTNSCHRINAKPSTKIISVLIKKADKQVAEALSIELEEKVICIKRLRLIDEVPVIFEVDYFRIDYMFLLKEE
LEDKSLMEVISNNISTLPKRVENIFEVKHSNKEYSDHLKCASNMPLLKVRQSVYTENNDVLYYNEQFIRSDKYKYAVSAE
I

Sequences:

>Translated_241_residues
MDLEVNSFVPLYQQLYDNIKKQIASGIYKPGDKLPSEGDLCKEFNISRITVRNALNELVKEDILCKKRGKGTYVTIPERI
EATCAGNSFTNSCHRINAKPSTKIISVLIKKADKQVAEALSIELEEKVICIKRLRLIDEVPVIFEVDYFRIDYMFLLKEE
LEDKSLMEVISNNISTLPKRVENIFEVKHSNKEYSDHLKCASNMPLLKVRQSVYTENNDVLYYNEQFIRSDKYKYAVSAE
I
>Mature_241_residues
MDLEVNSFVPLYQQLYDNIKKQIASGIYKPGDKLPSEGDLCKEFNISRITVRNALNELVKEDILCKKRGKGTYVTIPERI
EATCAGNSFTNSCHRINAKPSTKIISVLIKKADKQVAEALSIELEEKVICIKRLRLIDEVPVIFEVDYFRIDYMFLLKEE
LEDKSLMEVISNNISTLPKRVENIFEVKHSNKEYSDHLKCASNMPLLKVRQSVYTENNDVLYYNEQFIRSDKYKYAVSAE
I

Specific function: Possible Transcriptional Regulator Of The Succinyl-CoA- Synthetase Operon. Binds Specifically To The Farr Promoter And Exhibits Weak Binding To The Citrate Synthase And Lipoamide Dehydrogenase Promoters. Binding At The Farr Promoter Is Abolished By Long-

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=232, Percent_Identity=28.8793103448276, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1788418, Length=227, Percent_Identity=26.431718061674, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI87082252, Length=226, Percent_Identity=23.0088495575221, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1790118, Length=225, Percent_Identity=22.2222222222222, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1790540, Length=210, Percent_Identity=24.7619047619048, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27845; Mature: 27845

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLEVNSFVPLYQQLYDNIKKQIASGIYKPGDKLPSEGDLCKEFNISRITVRNALNELVK
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHH
EDILCKKRGKGTYVTIPERIEATCAGNSFTNSCHRINAKPSTKIISVLIKKADKQVAEAL
HHHHHHCCCCCCEEECHHHHHHEECCCCHHCHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
SIELEEKVICIKRLRLIDEVPVIFEVDYFRIDYMFLLKEELEDKSLMEVISNNISTLPKR
HHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHH
VENIFEVKHSNKEYSDHLKCASNMPLLKVRQSVYTENNDVLYYNEQFIRSDKYKYAVSAE
HHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEECHHHHHCCCEEEEEECC
I
C
>Mature Secondary Structure
MDLEVNSFVPLYQQLYDNIKKQIASGIYKPGDKLPSEGDLCKEFNISRITVRNALNELVK
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHH
EDILCKKRGKGTYVTIPERIEATCAGNSFTNSCHRINAKPSTKIISVLIKKADKQVAEAL
HHHHHHCCCCCCEEECHHHHHHEECCCCHHCHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
SIELEEKVICIKRLRLIDEVPVIFEVDYFRIDYMFLLKEELEDKSLMEVISNNISTLPKR
HHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHH
VENIFEVKHSNKEYSDHLKCASNMPLLKVRQSVYTENNDVLYYNEQFIRSDKYKYAVSAE
HHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEECHHHHHCCCEEEEEECC
I
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]