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The map label for this gene is apeA [H]

Identifier: 126698659

GI number: 126698659

Start: 1265562

End: 1266956

Strand: Direct

Name: apeA [H]

Synonym: CD1072

Alternate gene names: 126698659

Gene position: 1265562-1266956 (Clockwise)

Preceding gene: 126698658

Following gene: 126698660

Centisome position: 29.5

GC content: 31.47

Gene sequence:

>1395_bases
ATGAACTTAAAGTACGAATTTAAGAATGCTTGGGATTTTGAAAGAAAAGAAAATACTATTGAACAAATTATGCAATATTC
TAGCAATTATATGGAGTTTTTAAGTAAGTCAAAGACTGAAAGACTTTCAGTAAAAGAAATTATAAAATTGGCTAAAGAAA
ATAACTATATTTCAATAGATGAAGCTATGGAAAAAGGAAGCATAAGTTGTGGTGATAAAATTTATGTTATAAATAAAGAG
AAGGCAGTAGCACTTTTTGTAATAGGTAAAAATTATATAGAAAAAGGTATGAAGATTATAGGAAGCCATATAGATTCGCC
AAGATTAGATTTAAAACCAAATCCACTGTATCAAGAGAGTAATCTAGGTTTTTTTAAGACTCATTATTATGGTGGAATAA
AAAAATACCAATGGACGGCTATTCCACTTGCTTTACATGGTATAGTTATATTAAATGATGGAACAAAAGTGGACATATCT
ATTGGGGAAGAAGATAGTGACCCAGTATTTTGTGTAACTGATTTATTGATTCATTTGGCTGGAGACCAAATGCAAAAGAA
ACTATCAGAAGGAATTAGTGGAGAAGCTTTAAATATATTAATTGGGAATATTCCTTTAGAAGATGAAGAAAAAGAACCTA
TAACAGCAAATATATTAAAGATTTTAAATGAGAAATACAATATAGTTGAAGAAGATTTATTAAGTGCTGAAATTGAAGTA
GTTCCAGCTGGTAAGGCTAGAGATTTAGGGCTTGATAGGTCTATGGTGTTGGGATATGGGCATGATGATAGGGTATGTTC
ATATGCTGCTGTAAAAGCTATACTAGAAACTGAACAACCAGAATTTACTTCAGTTGCATTATGTGTAGATAAAGAAGAAA
TTGGTTCTAAAGGGAATACAGGTATGCACTCAAAGTTTTTTGAAAATACTGTGGCTGAACTGATTGCTTTAGAAGGAGAT
TATTGTGATATTAAAGTAAGAAGAGCTTTAGCAAATAGTAAGGTATTATCAGCTGATGTTTCTGCTGGATATGACCCAAA
TTTTGGAGAAGCATATGAAAAGAGAAATTCGGCATATATGGGAAATGGAGTAGTTTTAACTAAGTATACAGGTTCAAGAG
GAAAGAGTGGATGTAATGATGCTAATGCTGAATTTATGTCAGAAGTAAAGGGAATTTTTAATAAAGGAAATGTAATATGG
CAAACTGCTGAACTTGGAAAAGTAGACCAAGGAGGAGGCGGAACTATAGCCCATATATTGGCAAATCAAGGTGCAGAGGT
TATAGACTGTGGTGTTGGAGTTTTAAATATGCATGCACCACATGAGATTGTCTCTAAAGTAGACATATATGAAATGTATA
AGGGATATAAGGCATTTTTTAATATAAATTTATAA

Upstream 100 bases:

>100_bases
CACTTTAGATCAAGACTAGATAGTGTCAAAGTAGTTTCACCAGAAGAATATGAGCAATACATGAAAAACAATAAAAATTA
GAACTTAGTAGGAGGAAAAT

Downstream 100 bases:

>100_bases
GTAAAAATATAAATGTAATAAGTGAATAAAGGCTGTTGTATAAACAATTTAATCTGTTGTACAACAGTCTTATTTTTATG
TAAAAATAGCAATTTGTCAC

Product: aminopeptidase 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MNLKYEFKNAWDFERKENTIEQIMQYSSNYMEFLSKSKTERLSVKEIIKLAKENNYISIDEAMEKGSISCGDKIYVINKE
KAVALFVIGKNYIEKGMKIIGSHIDSPRLDLKPNPLYQESNLGFFKTHYYGGIKKYQWTAIPLALHGIVILNDGTKVDIS
IGEEDSDPVFCVTDLLIHLAGDQMQKKLSEGISGEALNILIGNIPLEDEEKEPITANILKILNEKYNIVEEDLLSAEIEV
VPAGKARDLGLDRSMVLGYGHDDRVCSYAAVKAILETEQPEFTSVALCVDKEEIGSKGNTGMHSKFFENTVAELIALEGD
YCDIKVRRALANSKVLSADVSAGYDPNFGEAYEKRNSAYMGNGVVLTKYTGSRGKSGCNDANAEFMSEVKGIFNKGNVIW
QTAELGKVDQGGGGTIAHILANQGAEVIDCGVGVLNMHAPHEIVSKVDIYEMYKGYKAFFNINL

Sequences:

>Translated_464_residues
MNLKYEFKNAWDFERKENTIEQIMQYSSNYMEFLSKSKTERLSVKEIIKLAKENNYISIDEAMEKGSISCGDKIYVINKE
KAVALFVIGKNYIEKGMKIIGSHIDSPRLDLKPNPLYQESNLGFFKTHYYGGIKKYQWTAIPLALHGIVILNDGTKVDIS
IGEEDSDPVFCVTDLLIHLAGDQMQKKLSEGISGEALNILIGNIPLEDEEKEPITANILKILNEKYNIVEEDLLSAEIEV
VPAGKARDLGLDRSMVLGYGHDDRVCSYAAVKAILETEQPEFTSVALCVDKEEIGSKGNTGMHSKFFENTVAELIALEGD
YCDIKVRRALANSKVLSADVSAGYDPNFGEAYEKRNSAYMGNGVVLTKYTGSRGKSGCNDANAEFMSEVKGIFNKGNVIW
QTAELGKVDQGGGGTIAHILANQGAEVIDCGVGVLNMHAPHEIVSKVDIYEMYKGYKAFFNINL
>Mature_464_residues
MNLKYEFKNAWDFERKENTIEQIMQYSSNYMEFLSKSKTERLSVKEIIKLAKENNYISIDEAMEKGSISCGDKIYVINKE
KAVALFVIGKNYIEKGMKIIGSHIDSPRLDLKPNPLYQESNLGFFKTHYYGGIKKYQWTAIPLALHGIVILNDGTKVDIS
IGEEDSDPVFCVTDLLIHLAGDQMQKKLSEGISGEALNILIGNIPLEDEEKEPITANILKILNEKYNIVEEDLLSAEIEV
VPAGKARDLGLDRSMVLGYGHDDRVCSYAAVKAILETEQPEFTSVALCVDKEEIGSKGNTGMHSKFFENTVAELIALEGD
YCDIKVRRALANSKVLSADVSAGYDPNFGEAYEKRNSAYMGNGVVLTKYTGSRGKSGCNDANAEFMSEVKGIFNKGNVIW
QTAELGKVDQGGGGTIAHILANQGAEVIDCGVGVLNMHAPHEIVSKVDIYEMYKGYKAFFNINL

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17552916, Length=464, Percent_Identity=23.9224137931034, Blast_Score=94, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6322746, Length=478, Percent_Identity=25.9414225941423, Blast_Score=108, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6321905, Length=481, Percent_Identity=24.1164241164241, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022983
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 51387; Mature: 51387

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKYEFKNAWDFERKENTIEQIMQYSSNYMEFLSKSKTERLSVKEIIKLAKENNYISID
CCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHCCCEEEHH
EAMEKGSISCGDKIYVINKEKAVALFVIGKNYIEKGMKIIGSHIDSPRLDLKPNPLYQES
HHHHCCCCCCCCEEEEEECCCEEEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
NLGFFKTHYYGGIKKYQWTAIPLALHGIVILNDGTKVDISIGEEDSDPVFCVTDLLIHLA
CCCEEEEEHCCCCCEEEEEEEEEEEEEEEEECCCCEEEEEECCCCCCCEEEHHHHHHHHC
GDQMQKKLSEGISGEALNILIGNIPLEDEEKEPITANILKILNEKYNIVEEDLLSAEIEV
CHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEE
VPAGKARDLGLDRSMVLGYGHDDRVCSYAAVKAILETEQPEFTSVALCVDKEEIGSKGNT
EECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEEHHHHCCCCCC
GMHSKFFENTVAELIALEGDYCDIKVRRALANSKVLSADVSAGYDPNFGEAYEKRNSAYM
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHCCCEEE
GNGVVLTKYTGSRGKSGCNDANAEFMSEVKGIFNKGNVIWQTAELGKVDQGGGGTIAHIL
CCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEEE
ANQGAEVIDCGVGVLNMHAPHEIVSKVDIYEMYKGYKAFFNINL
CCCCCCEEECCCCEEECCCCHHHHHHHHHHHHHCCEEEEEEECC
>Mature Secondary Structure
MNLKYEFKNAWDFERKENTIEQIMQYSSNYMEFLSKSKTERLSVKEIIKLAKENNYISID
CCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHCCCEEEHH
EAMEKGSISCGDKIYVINKEKAVALFVIGKNYIEKGMKIIGSHIDSPRLDLKPNPLYQES
HHHHCCCCCCCCEEEEEECCCEEEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
NLGFFKTHYYGGIKKYQWTAIPLALHGIVILNDGTKVDISIGEEDSDPVFCVTDLLIHLA
CCCEEEEEHCCCCCEEEEEEEEEEEEEEEEECCCCEEEEEECCCCCCCEEEHHHHHHHHC
GDQMQKKLSEGISGEALNILIGNIPLEDEEKEPITANILKILNEKYNIVEEDLLSAEIEV
CHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEE
VPAGKARDLGLDRSMVLGYGHDDRVCSYAAVKAILETEQPEFTSVALCVDKEEIGSKGNT
EECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEEHHHHCCCCCC
GMHSKFFENTVAELIALEGDYCDIKVRRALANSKVLSADVSAGYDPNFGEAYEKRNSAYM
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHCCCEEE
GNGVVLTKYTGSRGKSGCNDANAEFMSEVKGIFNKGNVIWQTAELGKVDQGGGGTIAHIL
CCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEEE
ANQGAEVIDCGVGVLNMHAPHEIVSKVDIYEMYKGYKAFFNINL
CCCCCCEEECCCCEEECCCCHHHHHHHHHHHHHCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]