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The map label for this gene is modB [H]

Identifier: 126698447

GI number: 126698447

Start: 1046780

End: 1047463

Strand: Direct

Name: modB [H]

Synonym: CD0870

Alternate gene names: 126698447

Gene position: 1046780-1047463 (Clockwise)

Preceding gene: 126698446

Following gene: 126698448

Centisome position: 24.4

GC content: 33.77

Gene sequence:

>684_bases
ATGGGAACAGATTGGTCACCCTTATGGATATCACTTAAGACATCTATTTTGTCAACAATAATAACTTTTGTAATAGGAAT
ATTTGTGTCATATATTATGGCTAACTATAGAGGTAAGTGGAAGGGTCTTATAGATGGACTATTTACACTTCCACTAATTT
TGCCACCAACAGTTGTAGGTTTCTTTTTATTATTACTATGTGGGAAGAATGGATTTATAGGAAAGTTTTTATTAAATTTC
GATAGGACTTTAATATTTAGTTGGACAGCAACTGTAATTTCAGCAGTAGTGGTGTCTTTTCCTATGATGTATAGAACTTC
AAGGTCAGCTTTTGAACAGATTGATAATAATATGCTGTCAGCTGCTAGAACATTAGGTCTTAATGAATGGAAAGTATTTT
TTAAGATTGCAGTTCCATTAGCATGGCCTGGAATAATTGGTGGATTGGTGCTGTCGTTTGCCAGAGCTCTTGGAGAATTT
GGTGCTACACTTATGATAGCTGGAAATATACCTGGAAAAACTCAAACTATGCCAATAGCTATATTTTTTGCTGTTGAAGG
CGGAGATATGAATAAAGCTATGATGTGGGTTATGATTATTGTAGCAATATCTATAGCAATGATTTTATTACTAAATTATT
GGTCGGAATTTCAGCAGAAAATTATAGGAAAGAGGTGTGGATAG

Upstream 100 bases:

>100_bases
ATGAAAATTGAAAATAATTGTGTATTATAATAAAATGGAAATAGTGAAATTAATAGAGTTATTAGTTTCACTATTTCCAT
TTAAAATTAAGGAGGGAAAG

Downstream 100 bases:

>100_bases
TTGAGCTTATACGTGGATATTGAAAAAGATTTATCCTCTTTTAAACTAAAGGTAGAAATTAAACAAGAAAAAGGTACTCT
GGGTTTTTTGGGAGAATCTG

Product: molybdenum ABC transporter permease

Products: ADP; phosphate; MoO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MGTDWSPLWISLKTSILSTIITFVIGIFVSYIMANYRGKWKGLIDGLFTLPLILPPTVVGFFLLLLCGKNGFIGKFLLNF
DRTLIFSWTATVISAVVVSFPMMYRTSRSAFEQIDNNMLSAARTLGLNEWKVFFKIAVPLAWPGIIGGLVLSFARALGEF
GATLMIAGNIPGKTQTMPIAIFFAVEGGDMNKAMMWVMIIVAISIAMILLLNYWSEFQQKIIGKRCG

Sequences:

>Translated_227_residues
MGTDWSPLWISLKTSILSTIITFVIGIFVSYIMANYRGKWKGLIDGLFTLPLILPPTVVGFFLLLLCGKNGFIGKFLLNF
DRTLIFSWTATVISAVVVSFPMMYRTSRSAFEQIDNNMLSAARTLGLNEWKVFFKIAVPLAWPGIIGGLVLSFARALGEF
GATLMIAGNIPGKTQTMPIAIFFAVEGGDMNKAMMWVMIIVAISIAMILLLNYWSEFQQKIIGKRCG
>Mature_226_residues
GTDWSPLWISLKTSILSTIITFVIGIFVSYIMANYRGKWKGLIDGLFTLPLILPPTVVGFFLLLLCGKNGFIGKFLLNFD
RTLIFSWTATVISAVVVSFPMMYRTSRSAFEQIDNNMLSAARTLGLNEWKVFFKIAVPLAWPGIIGGLVLSFARALGEFG
ATLMIAGNIPGKTQTMPIAIFFAVEGGDMNKAMMWVMIIVAISIAMILLLNYWSEFQQKIIGKRCG

Specific function: could be part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4149

COG function: function code P; ABC-type molybdate transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786980, Length=227, Percent_Identity=43.6123348017621, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1788764, Length=216, Percent_Identity=32.4074074074074, Blast_Score=123, Evalue=9e-30,
Organism=Escherichia coli, GI87082099, Length=174, Percent_Identity=27.5862068965517, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787369, Length=172, Percent_Identity=27.3255813953488, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011867 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 25155; Mature: 25023

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTDWSPLWISLKTSILSTIITFVIGIFVSYIMANYRGKWKGLIDGLFTLPLILPPTVVG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHH
FFLLLLCGKNGFIGKFLLNFDRTLIFSWTATVISAVVVSFPMMYRTSRSAFEQIDNNMLS
HHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AARTLGLNEWKVFFKIAVPLAWPGIIGGLVLSFARALGEFGATLMIAGNIPGKTQTMPIA
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEE
IFFAVEGGDMNKAMMWVMIIVAISIAMILLLNYWSEFQQKIIGKRCG
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GTDWSPLWISLKTSILSTIITFVIGIFVSYIMANYRGKWKGLIDGLFTLPLILPPTVVG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHH
FFLLLLCGKNGFIGKFLLNFDRTLIFSWTATVISAVVVSFPMMYRTSRSAFEQIDNNMLS
HHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AARTLGLNEWKVFFKIAVPLAWPGIIGGLVLSFARALGEFGATLMIAGNIPGKTQTMPIA
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEE
IFFAVEGGDMNKAMMWVMIIVAISIAMILLLNYWSEFQQKIIGKRCG
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; MoO42- [Periplasm]; H2O [C]

Specific reaction: ATP + MoO42- [Periplasm] + H2O = ADP + phosphate + MoO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]