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The map label for this gene is cdu2

Identifier: 126698235

GI number: 126698235

Start: 783839

End: 785032

Strand: Direct

Name: cdu2

Synonym: CD0657

Alternate gene names: NA

Gene position: 783839-785032 (Clockwise)

Preceding gene: 126698234

Following gene: 126698236

Centisome position: 18.27

GC content: 33.42

Gene sequence:

>1194_bases
ATGTTGACAAGTTTAGCTTTGATTTTTTTATTAGGAATGGCCTCGGGAGGTATTTTTAAGAGGATAAAATTACCTAACTT
ATTGGGAATGTTACTTACAGGAATTATATTAGGTCCATATGTTTTAAATTTGATTGATAATTCAATACTAGATATTTCTT
CTGACCTTAGAAAGATTGCATTGATTATTATATTAACAAGGGCTGGATTATCTTTAGATATAAACGATTTGAAGAAAGTG
GGAAGACCTGCTGTACTTATGTGCTTTATTCCAGCTACTTTTGAAATTATTGGAATGATAGTTTTAGCACCAAAATTACT
AGGCGTTTCTATATTGGAAGCAGCAGTCATGGGTGCAGTAGTAGGAGCAGTTTCTCCTGCAATTATTGTACCTAAAATGC
TTAAATTAATGGAAGAAGGTTATGGTACAGAAAAAAGTATTCCACAGATGCTTTTAGCAGGAACTTCTATAGACGATATT
TTCGTAATTGTGATGTTTACAGTATTCACAGGATTGGCACAAGGAAATAGTATATCAGCTATTAGTTTTTTACAAATTCC
AGTATCAATTATATTAGGTGTAATAGTTGGAGCAGTGATTGGAATCTGTTTAGCAGTATTTTTTAAGAAGGTTCATATGA
GAGATTCTGCTAAAGGGGTGTTGCTTTTAAGTATCTCATTTTTAATGATAAGTTTAGAGACTGCTTTAGAGGGTATTGTG
CCATTTTCTGGATTATTAGCAGTTATGAGTATTGGGATTTTCCTTCAGATAAAATATCGTGTAGTTGCAAGAAGATTGTC
TATAAAGTATTCGAAACTATGGGTTGGTGCTGAAATTCTCTTGTTTGTTTTGGTAGGGGCAACAGTAGATATAAGTTATG
CATTTAAAGCAGGAATTGGAGCTGTAATTTTAATATTTGGAGTTCTTTTATTCCGTATGGTAGGAGTATTCTTCTGCCTT
ATTAAGACAAATTTGACAATAAAGGAAAGGTTGTTCTGTATGATTGGCTATATTCCAAAGGCTACAGTACAGGCAGTAAT
AGGAGGTGTACCACTTGCAATGGGGATGGCATCTGGACAACTTATTTTGACGTTAGCAGTTCTCGCTATACTTATAACTG
CACCTCTTGGAGCTTTTGGAATTGATGTAACTTATAAAAAATTATTAACTTCTGTAAAAGGCGAGAGTAAGTAA

Upstream 100 bases:

>100_bases
CTATTTATTCACTACAAAAAATTTCAACAAAACAATAAATAAAACAACATAATGTATGATTAGAAGAGAAAGAATATTAG
AGAAAGGATAGGGTAGGAAT

Downstream 100 bases:

>100_bases
AAATAAAGATTATTTTAACTGGTAAGTTATATTTTGGAAAAGGATTATACTATTGAATACAATATAAAAAAATCATTTGG
GAGATTAAGAAGGTAGAAGT

Product: Na(+)/H(+) antiporter

Products: NA

Alternate protein names: Na(+)/H(+) Antiporter; Transporter CPA2 Family; Sodium/Proton Antiporter CPA1 Family; Na+/H+-Exchanging Protein; Na+/H+ Antiporter; Sodium/Hydrogen Antiporter; Sodium/Hydrogen Exchanger Family Protein; Transporter Monovalent CationProton Antiporter-2 Family; Na+/H+-Exchanging ProteinNa+/H+ Antiporter; Sodium/Hydrogen Exchanger/Universal Stress Family Protein; Monovalent CationProton Antiporter-2 Family Protein

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MLTSLALIFLLGMASGGIFKRIKLPNLLGMLLTGIILGPYVLNLIDNSILDISSDLRKIALIIILTRAGLSLDINDLKKV
GRPAVLMCFIPATFEIIGMIVLAPKLLGVSILEAAVMGAVVGAVSPAIIVPKMLKLMEEGYGTEKSIPQMLLAGTSIDDI
FVIVMFTVFTGLAQGNSISAISFLQIPVSIILGVIVGAVIGICLAVFFKKVHMRDSAKGVLLLSISFLMISLETALEGIV
PFSGLLAVMSIGIFLQIKYRVVARRLSIKYSKLWVGAEILLFVLVGATVDISYAFKAGIGAVILIFGVLLFRMVGVFFCL
IKTNLTIKERLFCMIGYIPKATVQAVIGGVPLAMGMASGQLILTLAVLAILITAPLGAFGIDVTYKKLLTSVKGESK

Sequences:

>Translated_397_residues
MLTSLALIFLLGMASGGIFKRIKLPNLLGMLLTGIILGPYVLNLIDNSILDISSDLRKIALIIILTRAGLSLDINDLKKV
GRPAVLMCFIPATFEIIGMIVLAPKLLGVSILEAAVMGAVVGAVSPAIIVPKMLKLMEEGYGTEKSIPQMLLAGTSIDDI
FVIVMFTVFTGLAQGNSISAISFLQIPVSIILGVIVGAVIGICLAVFFKKVHMRDSAKGVLLLSISFLMISLETALEGIV
PFSGLLAVMSIGIFLQIKYRVVARRLSIKYSKLWVGAEILLFVLVGATVDISYAFKAGIGAVILIFGVLLFRMVGVFFCL
IKTNLTIKERLFCMIGYIPKATVQAVIGGVPLAMGMASGQLILTLAVLAILITAPLGAFGIDVTYKKLLTSVKGESK
>Mature_397_residues
MLTSLALIFLLGMASGGIFKRIKLPNLLGMLLTGIILGPYVLNLIDNSILDISSDLRKIALIIILTRAGLSLDINDLKKV
GRPAVLMCFIPATFEIIGMIVLAPKLLGVSILEAAVMGAVVGAVSPAIIVPKMLKLMEEGYGTEKSIPQMLLAGTSIDDI
FVIVMFTVFTGLAQGNSISAISFLQIPVSIILGVIVGAVIGICLAVFFKKVHMRDSAKGVLLLSISFLMISLETALEGIV
PFSGLLAVMSIGIFLQIKYRVVARRLSIKYSKLWVGAEILLFVLVGATVDISYAFKAGIGAVILIFGVLLFRMVGVFFCL
IKTNLTIKERLFCMIGYIPKATVQAVIGGVPLAMGMASGQLILTLAVLAILITAPLGAFGIDVTYKKLLTSVKGESK

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI47271479, Length=359, Percent_Identity=33.1476323119777, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI66793392, Length=366, Percent_Identity=32.2404371584699, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI154937338, Length=300, Percent_Identity=30.6666666666667, Blast_Score=105, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17567635, Length=416, Percent_Identity=25.2403846153846, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI25152227, Length=427, Percent_Identity=24.5901639344262, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI32566724, Length=394, Percent_Identity=28.1725888324873, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI45550940, Length=384, Percent_Identity=32.03125, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI20129297, Length=384, Percent_Identity=32.03125, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24649169, Length=400, Percent_Identity=27.5, Blast_Score=101, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 42234; Mature: 42234

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTSLALIFLLGMASGGIFKRIKLPNLLGMLLTGIILGPYVLNLIDNSILDISSDLRKIA
CHHHHHHHHHHHHCCCCCEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIIILTRAGLSLDINDLKKVGRPAVLMCFIPATFEIIGMIVLAPKLLGVSILEAAVMGAV
HHHHEECCCCEECHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGAVSPAIIVPKMLKLMEEGYGTEKSIPQMLLAGTSIDDIFVIVMFTVFTGLAQGNSISA
HHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCH
ISFLQIPVSIILGVIVGAVIGICLAVFFKKVHMRDSAKGVLLLSISFLMISLETALEGIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCC
PFSGLLAVMSIGIFLQIKYRVVARRLSIKYSKLWVGAEILLFVLVGATVDISYAFKAGIG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHH
AVILIFGVLLFRMVGVFFCLIKTNLTIKERLFCMIGYIPKATVQAVIGGVPLAMGMASGQ
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHCCCHHHHHCCCCH
LILTLAVLAILITAPLGAFGIDVTYKKLLTSVKGESK
HHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLTSLALIFLLGMASGGIFKRIKLPNLLGMLLTGIILGPYVLNLIDNSILDISSDLRKIA
CHHHHHHHHHHHHCCCCCEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIIILTRAGLSLDINDLKKVGRPAVLMCFIPATFEIIGMIVLAPKLLGVSILEAAVMGAV
HHHHEECCCCEECHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGAVSPAIIVPKMLKLMEEGYGTEKSIPQMLLAGTSIDDIFVIVMFTVFTGLAQGNSISA
HHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCH
ISFLQIPVSIILGVIVGAVIGICLAVFFKKVHMRDSAKGVLLLSISFLMISLETALEGIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCC
PFSGLLAVMSIGIFLQIKYRVVARRLSIKYSKLWVGAEILLFVLVGATVDISYAFKAGIG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHH
AVILIFGVLLFRMVGVFFCLIKTNLTIKERLFCMIGYIPKATVQAVIGGVPLAMGMASGQ
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHCCCHHHHHCCCCH
LILTLAVLAILITAPLGAFGIDVTYKKLLTSVKGESK
HHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA