Click here to switch to the map view.

The map label for this gene is glsA

Identifier: 126698137

GI number: 126698137

Start: 664959

End: 665888

Strand: Direct

Name: glsA

Synonym: CD0558

Alternate gene names: 126698137

Gene position: 664959-665888 (Clockwise)

Preceding gene: 126698136

Following gene: 126698138

Centisome position: 15.5

GC content: 33.44

Gene sequence:

>930_bases
ATGAATACGTTAGATGAGACATTATTAAAAGAAATTATAAGTTCTAATAAGAAGTATACTAATTATGGACAAGTCGCTAG
TTACATCCCAGAATTAAAAAACGCTAGAAGAAATGATTTAGGAATTTGTATCATAGATAGCGAAAATAATCTTTATAGTG
CTGGAAACTGTAGCACAAAGTTTACTATACAAAGTATTTCAAAACCAATTGTGCTTGCTATGGCACTTATGGATAATGAT
TGGGAAGACGTTTTTTCAAACGTTGGAATGGAGCCAAGTGGGGACCCATTTAATTCAATAATGAAACTTGAAATTAATGA
CACAAAAAAACCCTGTAATCCAATGATAAATGCAGGGGCTATAGTAACCACTTCCCTTATAAATGGGAGTTGTTTAGAAG
AAAAAGAAGAAAGAATGCTTAGTTTCTTTAGAAAGTTAGCAAAAAATGATAATATAGGAATAAACTATGATGTCTATAAG
TCTGAAAAAATGACTGGAGATAGAAACAGAGCTATGGCTTACTTATTGAAAAGTGATGGATTTATCAGAGGGAATGTAGA
AGATGTTCTAGACCTTTATTTTAAACAATGCTCAATTGAGATAGATTCTGTAGATTTAGCGAGAATTGGAATAAATCTTG
CAAATTATGGAGTAGATATAGAAAATGGTGAGCATTTAATGAGTGAAATGGTTTCTAGGATTGTCAAGACATTTATGATG
ACTTGTGGAATGTATGATGCTTCTGGGGAATTTGCTATTAAAGTTGGCATTCCTGCAAAATCTGGAGTTGGGGGTGGTAT
AATGGCTTCTGTGCCGGGACGCATGGGGATTGGTGTTTATGGACCTGCGCTTGACAAAAAAGGTAACAGCGTCGCAGGAG
TTAAAGTTTTAGAGGAGTTGTCAAATAAACTCAAATTAAATATTTTTTAA

Upstream 100 bases:

>100_bases
TGTAGAAAATAATTTTAAAGTATAATTTTTTTTAACATTGTTTTATTATAGTATAAACTTGTGCTAAAATAGAATATATA
ACATAATATAAGAGGTGCAT

Downstream 100 bases:

>100_bases
AATATTAAGAAAGGATTTTTTTGACAACAACATATAATTTAATATATAATTAAATTGTAAAGAAATATGAATTAAATAAA
TTTTTTAGGAGGGGTCAATG

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICIIDSENNLYSAGNCSTKFTIQSISKPIVLAMALMDND
WEDVFSNVGMEPSGDPFNSIMKLEINDTKKPCNPMINAGAIVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYK
SEKMTGDRNRAMAYLLKSDGFIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGVDIENGEHLMSEMVSRIVKTFMM
TCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMGIGVYGPALDKKGNSVAGVKVLEELSNKLKLNIF

Sequences:

>Translated_309_residues
MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICIIDSENNLYSAGNCSTKFTIQSISKPIVLAMALMDND
WEDVFSNVGMEPSGDPFNSIMKLEINDTKKPCNPMINAGAIVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYK
SEKMTGDRNRAMAYLLKSDGFIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGVDIENGEHLMSEMVSRIVKTFMM
TCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMGIGVYGPALDKKGNSVAGVKVLEELSNKLKLNIF
>Mature_309_residues
MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICIIDSENNLYSAGNCSTKFTIQSISKPIVLAMALMDND
WEDVFSNVGMEPSGDPFNSIMKLEINDTKKPCNPMINAGAIVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYK
SEKMTGDRNRAMAYLLKSDGFIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGVDIENGEHLMSEMVSRIVKTFMM
TCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMGIGVYGPALDKKGNSVAGVKVLEELSNKLKLNIF

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family

Homologues:

Organism=Homo sapiens, GI156104878, Length=295, Percent_Identity=41.0169491525424, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI20336214, Length=281, Percent_Identity=39.1459074733096, Blast_Score=189, Evalue=4e-48,
Organism=Escherichia coli, GI1787804, Length=307, Percent_Identity=40.3908794788274, Blast_Score=233, Evalue=9e-63,
Organism=Escherichia coli, GI1786693, Length=312, Percent_Identity=39.1025641025641, Blast_Score=222, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI17507019, Length=292, Percent_Identity=40.4109589041096, Blast_Score=211, Evalue=6e-55,
Organism=Caenorhabditis elegans, GI17532727, Length=289, Percent_Identity=39.1003460207612, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI193204073, Length=315, Percent_Identity=37.1428571428571, Blast_Score=184, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI193204075, Length=316, Percent_Identity=36.3924050632911, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI281363239, Length=301, Percent_Identity=40.531561461794, Blast_Score=204, Evalue=6e-53,
Organism=Drosophila melanogaster, GI24653164, Length=301, Percent_Identity=40.531561461794, Blast_Score=204, Evalue=7e-53,
Organism=Drosophila melanogaster, GI281363241, Length=301, Percent_Identity=40.531561461794, Blast_Score=204, Evalue=7e-53,
Organism=Drosophila melanogaster, GI24653158, Length=301, Percent_Identity=40.531561461794, Blast_Score=204, Evalue=7e-53,
Organism=Drosophila melanogaster, GI24653156, Length=301, Percent_Identity=40.531561461794, Blast_Score=204, Evalue=8e-53,
Organism=Drosophila melanogaster, GI24653162, Length=301, Percent_Identity=40.531561461794, Blast_Score=204, Evalue=8e-53,
Organism=Drosophila melanogaster, GI116008307, Length=301, Percent_Identity=40.531561461794, Blast_Score=203, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24653166, Length=301, Percent_Identity=40.531561461794, Blast_Score=203, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLSA_CLOD6 (Q189A6)

Other databases:

- EMBL:   AM180355
- RefSeq:   YP_001087034.1
- ProteinModelPortal:   Q189A6
- SMR:   Q189A6
- STRING:   Q189A6
- GeneID:   4916196
- GenomeReviews:   AM180355_GR
- KEGG:   cdf:CD0558
- NMPDR:   fig|1496.1.peg.1585
- eggNOG:   COG2066
- HOGENOM:   HBG512335
- OMA:   FNPLINA
- ProtClustDB:   PRK00971
- HAMAP:   MF_00313
- InterPro:   IPR012338
- InterPro:   IPR015868
- Gene3D:   G3DSA:3.40.710.20
- PANTHER:   PTHR12544
- TIGRFAMs:   TIGR03814

Pfam domain/function: PF04960 Glutaminase; SSF56601 PBP_transp_fold

EC number: =3.5.1.2

Molecular weight: Translated: 33949; Mature: 33949

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICIIDSENNLYSAGNCSTK
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEECCCCCCE
FTIQSISKPIVLAMALMDNDWEDVFSNVGMEPSGDPFNSIMKLEINDTKKPCNPMINAGA
EEHHHCCCHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHCEEEEEECCCCCCCCCCCCCCC
IVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYKSEKMTGDRNRAMAYLLKSDG
EEEEHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHEEEEEECCC
FIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGVDIENGEHLMSEMVSRIVKTFMM
EEECCHHHHHHHHHHHHCCEECCEEHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHH
TCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMGIGVYGPALDKKGNSVAGVKVLEEL
HCCCCCCCCCEEEEECCCCCCCCCCCEEEECCCCCCCCEECCCCCCCCCCHHHHHHHHHH
SNKLKLNIF
HCCEEEECC
>Mature Secondary Structure
MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICIIDSENNLYSAGNCSTK
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEECCCCCCE
FTIQSISKPIVLAMALMDNDWEDVFSNVGMEPSGDPFNSIMKLEINDTKKPCNPMINAGA
EEHHHCCCHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHCEEEEEECCCCCCCCCCCCCCC
IVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYKSEKMTGDRNRAMAYLLKSDG
EEEEHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHEEEEEECCC
FIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGVDIENGEHLMSEMVSRIVKTFMM
EEECCHHHHHHHHHHHHCCEECCEEHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHH
TCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMGIGVYGPALDKKGNSVAGVKVLEEL
HCCCCCCCCCEEEEECCCCCCCCCCCEEEECCCCCCCCEECCCCCCCCCCHHHHHHHHHH
SNKLKLNIF
HCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA