| Definition | Clostridium difficile 630 chromosome, complete genome. |
|---|---|
| Accession | NC_009089 |
| Length | 4,290,252 |
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The map label for this gene is scrA [H]
Identifier: 126698045
GI number: 126698045
Start: 558197
End: 560071
Strand: Direct
Name: scrA [H]
Synonym: CD0469
Alternate gene names: 126698045
Gene position: 558197-560071 (Clockwise)
Preceding gene: 126698044
Following gene: 126698048
Centisome position: 13.01
GC content: 29.92
Gene sequence:
>1875_bases ATGAATAAATATAATAAAATAGCAAATGAGCTTATTAAAATTATTGGTGAAGATAATATTATTTCTATTACACATTGTGC CACAAGATTAAGAGTGATGGTTAAAGATAGAGAAATTATTAATGATAAGAAAGTTGAAAAAGTTGATGAGGTTAAAGGGG TTTTCTTTACTTCTGGACAGTATCAAATTATTTTAGGAACAGGAATAGTTAATAAAGTTTATGCAGAAGTTGAAAAAATG GGATTAAAAACTTTATCAAAAAAAGAACAAGATGAATTAGTTAAAAATAATGAAACTGGATTTAAGAAAGTTATGAGAAC TCTAGCAGATATATTTGTTCCTATTATTCCAGTTATTGCAGCAACAGGATTATTCTTGGGATTAAAGGGTTGTTTGTTTA ATGATAATGTACTTGGATTATTTGGAATGTCTTCTGCAAATATTCCATTGTATATTCAGACACTTGTTTCGGTTCTTACA GAAACAGCATTTGCTTTTTTACCAGCAATTATTGTATGGTCAGCATTTAAAGTATTTGGAGGAACACCTGTTATTGGACT TGTTATTGGACTTATGTTAGTTTCCCCAATACTTCCTAATGCATATTCTGTTGCTGACCCATCAAATGAAATTGAAGCAA TTATGGCATTTGGATTTATTCCTATTGTAGGTTGTCAAGGAAGTGTTTTAACAGCTATTGTTACAGCATTTATTGGAGCT AATCTTGAAAAATGGTTCCGTAAACATATGCCTAATGTATTAGACCTTATTTTCACACCATTTTTTGTTATGCTAATAAC AATGTTAGTTATTTTGTTAGGTGTAGGCCCTATAATGCATACAATAGAATTAAAAATGGTTGATATCATCAGCTTATTGA TTGATTTGCCTTTAGGAATTGGAGGATTTATTATTGGATTTACATATCCATTAGCTGTTATTACTGGCTTACATCATACT TATGTAATGATTGAAACATCACTATTAGCAAATACAGGATTTAATGCCCTTATTACTCTTTGTGCAATGTATGGATTTGC GAATATTGGAACATGTCTAGCATTTATGAAAAAATCTAAAAATAATCAAGTTAAACAAACTGCGGTTGGAGCAATGCTAT CTCAACTTTTTGGTATAAGTGAGCCTGTTTTATTTGGGATTCAGCTTCGATATAATTTAAAGCCTTTGATTATTATGTGT GCATCTTCAGGTTTAGGAGCAGCAATATTATCAATTTTACATATTCAATCTAATTCATATGGATTAGCAGTTTTACCTTC TTATTTAATGTATATCTATGATGGATATAATTTAATCACATACTTATTAGTATCAATATTTGTGGTTGCATTCTGCTTTA TTGTAACATGTTTATTTGGAGTGCCTAAAGAAGCTATAAATGAAGATGAAGACGAAGAATTAGTGTTTAATGAAAATAAT GAAAACTTTGTGTCTCCAGCTAAGGGGAAAATTGTTGCATTAGAAAATGTACCAGATGAAACATTTTCTAAAAAAATGTT AGGTGATGGTTTTGCTATTGATATTATAGATGGAAAAATTGTTTCTCCTATTTCAGGTAAATTAGAAACAGTGTTTTCAA GTGGACATGCATTTGGGATTAAAGGAACTAATGGAGAAGTATTAATTCATGTTGGAATTGATACAGTTGCATTAAATGGA GATGGCTTTGATGTTGCTGTTAAACAAGGAGATATGGTTAAACAGGGGGATGTTCTTGTTAATGTTGATTTAAAGAGAAT ACATGAATTAGGAAAGTCTACTTTGACAATGGTATTGTTTCCAGATGGTAAGAAGGTAAATATTTTGGATATAAACAAGG ATGTAAAAATAGGTCAAAGAATATGTGTTGAGTAG
Upstream 100 bases:
>100_bases TATGATATTGTATTCCAAAATTTAGATGATATAAATCTATTAAATAAAACAGTGCGTTTGAAACCATTTCATGCAGTATT ATTGAAAGTGAGGTAGAAAA
Downstream 100 bases:
>100_bases TAGGTTATATGTAATGACTACAAAAGAAGATTATCAAGAGTAATTCAATCTTTTTAAAGTATGAGAAATAATTCATAAAC TCTAAAACAATTAAAGAGGT
Product: PTS system transporter subunit IIABC
Products: NA
Alternate protein names: EIIBCA-Scr; EII-Scr; Sucrose-specific phosphotransferase enzyme IIB component; PTS system sucrose-specific EIIB component; Sucrose permease IIC component; PTS system sucrose-specific EIIC component; Sucrose-specific phosphotransferase enzyme IIA component; PTS system sucrose-specific EIIA component [H]
Number of amino acids: Translated: 624; Mature: 624
Protein sequence:
>624_residues MNKYNKIANELIKIIGEDNIISITHCATRLRVMVKDREIINDKKVEKVDEVKGVFFTSGQYQIILGTGIVNKVYAEVEKM GLKTLSKKEQDELVKNNETGFKKVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFGFIPIVGCQGSVLTAIVTAFIGA NLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVGPIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHT YVMIETSLLANTGFNALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYNLKPLIIMC ASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLVSIFVVAFCFIVTCLFGVPKEAINEDEDEELVFNENN ENFVSPAKGKIVALENVPDETFSKKMLGDGFAIDIIDGKIVSPISGKLETVFSSGHAFGIKGTNGEVLIHVGIDTVALNG DGFDVAVKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
Sequences:
>Translated_624_residues MNKYNKIANELIKIIGEDNIISITHCATRLRVMVKDREIINDKKVEKVDEVKGVFFTSGQYQIILGTGIVNKVYAEVEKM GLKTLSKKEQDELVKNNETGFKKVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFGFIPIVGCQGSVLTAIVTAFIGA NLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVGPIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHT YVMIETSLLANTGFNALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYNLKPLIIMC ASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLVSIFVVAFCFIVTCLFGVPKEAINEDEDEELVFNENN ENFVSPAKGKIVALENVPDETFSKKMLGDGFAIDIIDGKIVSPISGKLETVFSSGHAFGIKGTNGEVLIHVGIDTVALNG DGFDVAVKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE >Mature_624_residues MNKYNKIANELIKIIGEDNIISITHCATRLRVMVKDREIINDKKVEKVDEVKGVFFTSGQYQIILGTGIVNKVYAEVEKM GLKTLSKKEQDELVKNNETGFKKVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFGFIPIVGCQGSVLTAIVTAFIGA NLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVGPIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHT YVMIETSLLANTGFNALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYNLKPLIIMC ASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLVSIFVVAFCFIVTCLFGVPKEAINEDEDEELVFNENN ENFVSPAKGKIVALENVPDETFSKKMLGDGFAIDIIDGKIVSPISGKLETVFSSGHAFGIKGTNGEVLIHVGIDTVALNG DGFDVAVKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This
COG id: COG1263
COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PTS EIIC type-1 domain [H]
Homologues:
Organism=Escherichia coli, GI1790159, Length=598, Percent_Identity=29.4314381270903, Blast_Score=232, Evalue=7e-62, Organism=Escherichia coli, GI2367362, Length=441, Percent_Identity=28.1179138321995, Blast_Score=180, Evalue=2e-46, Organism=Escherichia coli, GI1788769, Length=478, Percent_Identity=25.1046025104602, Blast_Score=130, Evalue=2e-31, Organism=Escherichia coli, GI48994906, Length=510, Percent_Identity=25.2941176470588, Blast_Score=113, Evalue=3e-26, Organism=Escherichia coli, GI1788757, Length=119, Percent_Identity=42.0168067226891, Blast_Score=99, Evalue=1e-21, Organism=Escherichia coli, GI1786894, Length=117, Percent_Identity=40.1709401709402, Blast_Score=95, Evalue=2e-20,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011055 - InterPro: IPR018113 - InterPro: IPR001127 - InterPro: IPR001996 - InterPro: IPR003352 - InterPro: IPR013013 - InterPro: IPR011535 - InterPro: IPR010973 [H]
Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]
EC number: =2.7.1.69 [H]
Molecular weight: Translated: 67962; Mature: 67962
Theoretical pI: Translated: 6.07; Mature: 6.07
Prosite motif: PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.4 %Cys (Translated Protein) 3.4 %Met (Translated Protein) 4.8 %Cys+Met (Translated Protein) 1.4 %Cys (Mature Protein) 3.4 %Met (Mature Protein) 4.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNKYNKIANELIKIIGEDNIISITHCATRLRVMVKDREIINDKKVEKVDEVKGVFFTSGQ CCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCEEEECCC YQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFKKVMRTLADIFVPIIPVIA EEEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH ATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLTETAFAFLPAIIVWSAFKVFG HHHHHHHHHCCEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC GTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFGFIPIVGCQGSVLTAIVTAFIGA CCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCHHEECCCCHHHHHHHHHHHCC NLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVGPIMHTIELKMVDIISLLIDLPLGI CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCC GGFIIGFTYPLAVITGLHHTYVMIETSLLANTGFNALITLCAMYGFANIGTCLAFMKKSK HHHHHHHHHHHHHHHHCCCEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC NNQVKQTAVGAMLSQLFGISEPVLFGIQLRYNLKPLIIMCASSGLGAAILSILHIQSNSY CCHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCEEEEEEECCCHHHHHHHHHHCCCCCC GLAVLPSYLMYIYDGYNLITYLLVSIFVVAFCFIVTCLFGVPKEAINEDEDEELVFNENN CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEECCC ENFVSPAKGKIVALENVPDETFSKKMLGDGFAIDIIDGKIVSPISGKLETVFSSGHAFGI CCCCCCCCCCEEEEECCCCHHHHHHHCCCCCEEEEECCCEECCCCCHHHHHHCCCCEEEE KGTNGEVLIHVGIDTVALNGDGFDVAVKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLF ECCCCCEEEEECCEEEEECCCCCEEEEECCCCEECCCEEEEECHHHHHHCCCCEEEEEEE PDGKKVNILDINKDVKIGQRICVE CCCCEEEEEECCCCCHHCHHHCCC >Mature Secondary Structure MNKYNKIANELIKIIGEDNIISITHCATRLRVMVKDREIINDKKVEKVDEVKGVFFTSGQ CCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCEEEECCC YQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFKKVMRTLADIFVPIIPVIA EEEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH ATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLTETAFAFLPAIIVWSAFKVFG HHHHHHHHHCCEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC GTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFGFIPIVGCQGSVLTAIVTAFIGA CCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCHHEECCCCHHHHHHHHHHHCC NLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVGPIMHTIELKMVDIISLLIDLPLGI CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCC GGFIIGFTYPLAVITGLHHTYVMIETSLLANTGFNALITLCAMYGFANIGTCLAFMKKSK HHHHHHHHHHHHHHHHCCCEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC NNQVKQTAVGAMLSQLFGISEPVLFGIQLRYNLKPLIIMCASSGLGAAILSILHIQSNSY CCHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCEEEEEEECCCHHHHHHHHHHCCCCCC GLAVLPSYLMYIYDGYNLITYLLVSIFVVAFCFIVTCLFGVPKEAINEDEDEELVFNENN CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEECCC ENFVSPAKGKIVALENVPDETFSKKMLGDGFAIDIIDGKIVSPISGKLETVFSSGHAFGI CCCCCCCCCCEEEEECCCCHHHHHHHCCCCCEEEEECCCEECCCCCHHHHHHCCCCEEEE KGTNGEVLIHVGIDTVALNGDGFDVAVKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLF ECCCCCEEEEECCEEEEECCCCCEEEEECCCCEECCCEEEEECHHHHHHCCCCEEEEEEE PDGKKVNILDINKDVKIGQRICVE CCCCEEEEEECCCCCHHCHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA