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The map label for this gene is malL [H]

Identifier: 126698044

GI number: 126698044

Start: 556528

End: 558192

Strand: Direct

Name: malL [H]

Synonym: CD0468

Alternate gene names: 126698044

Gene position: 556528-558192 (Clockwise)

Preceding gene: 126698043

Following gene: 126698045

Centisome position: 12.97

GC content: 29.79

Gene sequence:

>1665_bases
ATGGAAAAGAAATGGTGGCAAAAAGAAATCGTTTATCAAATTTATCCAAGAAGCTTTCAAGATAGTAATAATGATGGAAT
TGGAGATTTACAGGGAATTATTTCTCGTTTAGATTATTTAAAAGATTTAGGTATTACATCATTGTGGTTATGTCCAATTT
TTAAATCACCTATGGACGATAATGGGTATGATATTAGTGATTATTTGGATATTGCAAGTGAATTTGGAAGTATGGAAGAT
TTAAAAGAGTTAATTAAAGAAAGTAAAGATAGAGGAATCAAAATTATATTAGATTTAGTTCTTAATCATACAAGTGATGA
ACATCCTTGGTTTCAAGAAGCATTAAAAAATCCAGAAAGTCCTTATCATGATTATTATATTTTTAAAAAAGGAAACGATT
TACCAAATAACTGGAGGTCTGTTTTTGGTGGAAGTGTTTGGGAAAAGGTAGAGAATAGAGACGAATATTATTTTCATTCT
TTTGGTAAAAAACAACCTGACCTTAATTGGGAAAATCCAATATTAAGAAGTGAACTTTACCAAATGATTAATACCTGGTC
TCAAATGGGAGTGGCAGGATTTAGAGTTGATGCTATTACATTTATCAAAAAGAATTTAAGTTTTCAAAGTTTAGAAAGTG
ATGGTGTTGATGGTCTTGTTAAATGTACAAAAACAGTTAGAAATCAGCCTGGAATAGAAAAAATGCTTTATGAATTAAAA
GAAAATACGTTTAAAAAATATGATTGTATGACTGTTGCTGAAGCAGCAGGTATTAGCTATGACCAACTAGGTGATTTTAT
TGGAGAAGATGGTTTCTTTTCAATGGTCTTTGACTTTAAACATGCTGACTTAGATGTTGCTTCTGGTAGTGAGTGGTTTA
AAAGAATTTCATGGACAATTCCAGATTTAAGAAAATGCATTTTAGATAGTCAAATGTATGTTCAGGAACATGGATGGGCA
GCTAATTTTATTGAAAATCATGACCAACCAAGAGCTACAACAAAGTATCTTTTGCAATACGAAAGGAATGATGATGCAGT
AAAAATGTTGGGAGCAATGTATTTCTTTTTAAGAGGAACCCCATTTATTTATCAGGGACAGGAATTAGGAATGACAAATT
TTAAAAGAGATACCATAAATGATTTTAATGATTTATCTAGCATTGACCAATACTATCGTTCAATAGATGAAAGTTACTCA
GAAGAAGAAGCGTTAGAATTTGTGAATTTAAGAAGCCGAGATAATGCAAGAACGCCATTTCCATGGGCAGATAAAGAAAA
TGCAGGTTTTTCAGATACAACACCATGGTTAAAGGTTATTGAAAATTATAAAGATATTAATGCACAGAGTCAGATTAACA
ATTCAGAGAGTATTTTAGAATTTTATAAAAAGATGATAAAGTTGAGACAAGATAGTGAGTATTCTGATTGTTTGATTTAT
GGTTCAATAGAACCTATTGATATAGAAAGTGATGATATTATTGCGTATAGAAGGCAATTAGATTTGGTAGTTATTGATTG
TTATTATAATTTTTCTGATAAACCTGTAGAAATAAGAGTAGAAGAAAAATATGATATTGTATTCCAAAATTTAGATGATA
TAAATCTATTAAATAAAACAGTGCGTTTGAAACCATTTCATGCAGTATTATTGAAAGTGAGGTAG

Upstream 100 bases:

>100_bases
CAACTTAAAGATATAGCGACATCTATATGTGAGGACATATTCGATAATGGAATTTATAAAGAATTAAAAAGAAGAAATAT
CATATAAAAAGGAGTAATTT

Downstream 100 bases:

>100_bases
AAAAATGAATAAATATAATAAAATAGCAAATGAGCTTATTAAAATTATTGGTGAAGATAATATTATTTCTATTACACATT
GTGCCACAAGATTAAGAGTG

Product: oligo-1,6-glucosidase

Products: NA

Alternate protein names: Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase; Sucrase-isomaltase; Isomaltase [H]

Number of amino acids: Translated: 554; Mature: 554

Protein sequence:

>554_residues
MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKDLGITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMED
LKELIKESKDRGIKIILDLVLNHTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDGLVKCTKTVRNQPGIEKMLYELK
ENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMVFDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWA
ANFIENHDQPRATTKYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYYRSIDESYS
EEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQSQINNSESILEFYKKMIKLRQDSEYSDCLIY
GSIEPIDIESDDIIAYRRQLDLVVIDCYYNFSDKPVEIRVEEKYDIVFQNLDDINLLNKTVRLKPFHAVLLKVR

Sequences:

>Translated_554_residues
MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKDLGITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMED
LKELIKESKDRGIKIILDLVLNHTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDGLVKCTKTVRNQPGIEKMLYELK
ENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMVFDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWA
ANFIENHDQPRATTKYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYYRSIDESYS
EEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQSQINNSESILEFYKKMIKLRQDSEYSDCLIY
GSIEPIDIESDDIIAYRRQLDLVVIDCYYNFSDKPVEIRVEEKYDIVFQNLDDINLLNKTVRLKPFHAVLLKVR
>Mature_554_residues
MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKDLGITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMED
LKELIKESKDRGIKIILDLVLNHTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDGLVKCTKTVRNQPGIEKMLYELK
ENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMVFDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWA
ANFIENHDQPRATTKYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYYRSIDESYS
EEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQSQINNSESILEFYKKMIKLRQDSEYSDCLIY
GSIEPIDIESDDIIAYRRQLDLVVIDCYYNFSDKPVEIRVEEKYDIVFQNLDDINLLNKTVRLKPFHAVLLKVR

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=498, Percent_Identity=30.3212851405622, Blast_Score=219, Evalue=8e-57,
Organism=Homo sapiens, GI61744475, Length=109, Percent_Identity=38.5321100917431, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI61744477, Length=109, Percent_Identity=38.5321100917431, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI65506891, Length=109, Percent_Identity=38.5321100917431, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI61744483, Length=109, Percent_Identity=38.5321100917431, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI61744479, Length=109, Percent_Identity=38.5321100917431, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI61744481, Length=109, Percent_Identity=38.5321100917431, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1790687, Length=555, Percent_Identity=35.8558558558559, Blast_Score=375, Evalue=1e-105,
Organism=Escherichia coli, GI1786604, Length=108, Percent_Identity=41.6666666666667, Blast_Score=89, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI32565753, Length=570, Percent_Identity=22.9824561403509, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI25147709, Length=204, Percent_Identity=29.9019607843137, Blast_Score=90, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6322245, Length=580, Percent_Identity=35, Blast_Score=340, Evalue=4e-94,
Organism=Saccharomyces cerevisiae, GI6319776, Length=586, Percent_Identity=34.3003412969283, Blast_Score=306, Evalue=7e-84,
Organism=Saccharomyces cerevisiae, GI6321731, Length=586, Percent_Identity=34.1296928327645, Blast_Score=305, Evalue=1e-83,
Organism=Saccharomyces cerevisiae, GI6321726, Length=580, Percent_Identity=31.8965517241379, Blast_Score=288, Evalue=2e-78,
Organism=Saccharomyces cerevisiae, GI6324416, Length=584, Percent_Identity=32.7054794520548, Blast_Score=284, Evalue=2e-77,
Organism=Saccharomyces cerevisiae, GI6322241, Length=584, Percent_Identity=32.7054794520548, Blast_Score=283, Evalue=3e-77,
Organism=Saccharomyces cerevisiae, GI6322021, Length=584, Percent_Identity=32.7054794520548, Blast_Score=283, Evalue=3e-77,
Organism=Drosophila melanogaster, GI24583745, Length=523, Percent_Identity=37.2848948374761, Blast_Score=283, Evalue=2e-76,
Organism=Drosophila melanogaster, GI24583749, Length=552, Percent_Identity=34.4202898550725, Blast_Score=278, Evalue=9e-75,
Organism=Drosophila melanogaster, GI24583747, Length=552, Percent_Identity=34.4202898550725, Blast_Score=278, Evalue=9e-75,
Organism=Drosophila melanogaster, GI24586599, Length=542, Percent_Identity=33.5793357933579, Blast_Score=268, Evalue=1e-71,
Organism=Drosophila melanogaster, GI45549022, Length=539, Percent_Identity=33.7662337662338, Blast_Score=256, Evalue=4e-68,
Organism=Drosophila melanogaster, GI24586587, Length=502, Percent_Identity=32.6693227091633, Blast_Score=249, Evalue=4e-66,
Organism=Drosophila melanogaster, GI24586589, Length=525, Percent_Identity=32.7619047619048, Blast_Score=240, Evalue=2e-63,
Organism=Drosophila melanogaster, GI221330053, Length=205, Percent_Identity=52.1951219512195, Blast_Score=229, Evalue=4e-60,
Organism=Drosophila melanogaster, GI24586597, Length=208, Percent_Identity=49.0384615384615, Blast_Score=218, Evalue=8e-57,
Organism=Drosophila melanogaster, GI24586593, Length=206, Percent_Identity=50.9708737864078, Blast_Score=216, Evalue=3e-56,
Organism=Drosophila melanogaster, GI24586591, Length=202, Percent_Identity=49.5049504950495, Blast_Score=212, Evalue=6e-55,
Organism=Drosophila melanogaster, GI281360393, Length=152, Percent_Identity=44.7368421052632, Blast_Score=134, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.10 [H]

Molecular weight: Translated: 64958; Mature: 64958

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKDLGITSLWLCPIFKSPMDD
CCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCC
NGYDISDYLDIASEFGSMEDLKELIKESKDRGIKIILDLVLNHTSDEHPWFQEALKNPES
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHCCCCC
PYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHSFGKKQPDLNWENPILRSELY
CCCCEEEEECCCCCCHHHHHHHCCHHHHHHHCCCCHHHHHCCCCCCCCCCCCCHHHHHHH
QMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDGLVKCTKTVRNQPGIEKMLYELK
HHHHHHHHHCCCCEEHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHH
ENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMVFDFKHADLDVASGSEWFKRISWTI
HHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCC
PDLRKCILDSQMYVQEHGWAANFIENHDQPRATTKYLLQYERNDDAVKMLGAMYFFLRGT
HHHHHHHHCCHHHHHHCCCCHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
PFIYQGQELGMTNFKRDTINDFNDLSSIDQYYRSIDESYSEEEALEFVNLRSRDNARTPF
CEEEECCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCC
PWADKENAGFSDTTPWLKVIENYKDINAQSQINNSESILEFYKKMIKLRQDSEYSDCLIY
CCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEE
GSIEPIDIESDDIIAYRRQLDLVVIDCYYNFSDKPVEIRVEEKYDIVFQNLDDINLLNKT
CCCCCCCCCCCCHHHHHHHCCEEEEEEEECCCCCCEEEEECCCHHHHHHCCCHHHHHHHH
VRLKPFHAVLLKVR
HCCCHHHHEEEECC
>Mature Secondary Structure
MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKDLGITSLWLCPIFKSPMDD
CCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCC
NGYDISDYLDIASEFGSMEDLKELIKESKDRGIKIILDLVLNHTSDEHPWFQEALKNPES
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHCCCCC
PYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHSFGKKQPDLNWENPILRSELY
CCCCEEEEECCCCCCHHHHHHHCCHHHHHHHCCCCHHHHHCCCCCCCCCCCCCHHHHHHH
QMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDGLVKCTKTVRNQPGIEKMLYELK
HHHHHHHHHCCCCEEHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHH
ENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMVFDFKHADLDVASGSEWFKRISWTI
HHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCC
PDLRKCILDSQMYVQEHGWAANFIENHDQPRATTKYLLQYERNDDAVKMLGAMYFFLRGT
HHHHHHHHCCHHHHHHCCCCHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
PFIYQGQELGMTNFKRDTINDFNDLSSIDQYYRSIDESYSEEEALEFVNLRSRDNARTPF
CEEEECCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCC
PWADKENAGFSDTTPWLKVIENYKDINAQSQINNSESILEFYKKMIKLRQDSEYSDCLIY
CCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEE
GSIEPIDIESDDIIAYRRQLDLVVIDCYYNFSDKPVEIRVEEKYDIVFQNLDDINLLNKT
CCCCCCCCCCCCHHHHHHHCCEEEEEEEECCCCCCEEEEECCCHHHHHHCCCHHHHHHHH
VRLKPFHAVLLKVR
HCCCHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1761534 [H]