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The map label for this gene is helD [H]

Identifier: 126698031

GI number: 126698031

Start: 539697

End: 541811

Strand: Direct

Name: helD [H]

Synonym: CD0455

Alternate gene names: 126698031

Gene position: 539697-541811 (Clockwise)

Preceding gene: 126698030

Following gene: 126698033

Centisome position: 12.58

GC content: 29.22

Gene sequence:

>2115_bases
ATGTCTGAAAATAAACAAGTAGTAAATTGCGATATTATTGCATCTAATTCTAAACATAATATGTGTGAATATGATGCAGA
GTTATTAACTTTTTTTCCAGATGAGATTGCACATCTAATAGAGATAAATAACAAGCTAGACAATGCTTTTAAGAAAGCTG
AAAATCTTGTTGACAAGCTTGATAAGGATTATATGGACGCTAAAATGTATATGGTAAAAAATCGTGGTGAAATAGACCCA
CATGAAATGTTTCAAAATGAACAAGGACTAAAACAAATAGATAACTATGGGGCTTTTATGGTAAAAGTTCGAGGTAAGAT
TAATAAAATCAAAGATTCTCCATACTTTGCTAGAATAGATTTTAGGCTGAAAGATATGGATGATGAATCTAAGTATTATA
TTGGTAGATTTGCATTTGATTATGAAGATGAGCTTATAATACTTGACTGGCGTTCTCCAATTGCCAGTATGTTTTATGAT
TATGAAATCGGAAAAGCTGGATATGATGCTCCAATAGGATGGGTGGATGGAGAAATAACAAGAAAACGACAATTTAAAAT
TAAAAATGGAAAATTAGAATATGCACTAGAAAGTTCCATTAATATACAAGATGATATTCTTCAAAAAGAACTTAGTCACA
CTTCAGATGAAAAAATGAAGTCAATCATTTCAACAATACAAAAGGAACAAAATCAAATTATTAGAAATGATAAAGCTGAT
ACACTGATTATTCAAGGGGTAGCTGGTTCTGGGAAAACATCTATAGCATTACACAGAATTGCTTTTCTTCTTTATCGATT
TAAAGATAAAATATCAGCAAATAATGTAATTATCCTATCACCTAATAAAGTCTTTGGAGACTATATTTCCAATGTCCTTC
CTGAGCTTGGAGAAGAGCCATTATGTGAATTAAGTTTTGAAAATATAGCAGAGGTACAATTAGATAGAGTTATTAATTTT
GAAAGTGAGAAAGACCCATTAGAAATAAATGATGCTAAATGGTCTGAAAGAGTGCGTTTTAAATCTACACTTGATTTTGT
AAAACTTATTGATGATTATATAAAACAAATGCCAAATAAGATTTTTATTCCAAAAGACTACACTTTTGGAAGTTTTACAG
CTAAAAGTGACTGGATACAGAGTAGATTTGAGGCATATAACAGATATCCAGTTAAGAAGAGATTAGAGAAGGTAGCTGAA
GACATTCATTATAAATTTGAATCAGATAATATTATGGAAGAAGATTTACCAAAGGTAAAAAGTATACTTAAAAGTTTGAA
TGGAATGTTGACAATAAAAAATACTCTTACACTATATAAGGATTTCTTTAAACAAATGAATATATCAAACATGTTTGTGA
TGGTAGAAAAGAAAACACTTGAATGGTCAGATGTATACCCATTTATATATATTCATGCTGCATATGAAGGTATACAAGAA
GATAAGATTATAAGGCATATTGTTATTGATGAAATGCAGGATTATACACCTATTCAATATGCTGTAATAAACTTACTTTT
TAAGTGTAAAAAGACTATTCTTGGAGATTTTGGACAATTGGTTAATCCTAATCATACTCATACATTAGATGATATGAAAC
AGCTATATAATGATGGAGAATTAGTTATGTTGAACAAGAGTTACCGTTCTACTTTTGAGATTATTAATTTCGCCAAAAAG
ATTCAAGACATATCTTCATTAGAGCCTATTGAACGACATGGTGAAGAACCAGCTTTATTAAAATGTAATAACGAGCAAGA
TGAAATAAATAAGATAAAAATAGAAATTGAAGAATTTAAAAAGAGTGATAATGCGACTCTTGGTATTATATTAAAGACAG
ATAATGACGCTAAAGCTGTATATGATGCGTTAAGAGAAGAATATAGTGTTCACTTAATATCTTCTGAAAGTTCTAGCTTT
ACAAAAGGAGTATCCATAACTTCTATTAAAATGTCAAAAGGTTTAGAGTTTGATGAAGTTATTGTACCTTCAGTAAATAA
TAAAACATATTATAGTGATTATGACCACAGTTTGTTATATATTGCCTGTACACGAGCTATGCACAAACTTAAGTTAACAT
ATGTTGGTACATTAACTCAACTTATAAGCATGTAG

Upstream 100 bases:

>100_bases
TTCTTCCTTTAAGTTAAATAGCAAGAATGATTAAAAACTCCAAAACACAATTAAGTATAATGATTCAGTGTAAGTACTTA
ATTAACAAAGGAGGATTTAA

Downstream 100 bases:

>100_bases
ATTATATCTTATATGCATTTATTATCGTAAATATAAATTGGGACAAAGATTCATCAATAAATCAACAAAAAATAATACCT
ATAAATTTATAAAAAATGAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 704; Mature: 703

Protein sequence:

>704_residues
MSENKQVVNCDIIASNSKHNMCEYDAELLTFFPDEIAHLIEINNKLDNAFKKAENLVDKLDKDYMDAKMYMVKNRGEIDP
HEMFQNEQGLKQIDNYGAFMVKVRGKINKIKDSPYFARIDFRLKDMDDESKYYIGRFAFDYEDELIILDWRSPIASMFYD
YEIGKAGYDAPIGWVDGEITRKRQFKIKNGKLEYALESSINIQDDILQKELSHTSDEKMKSIISTIQKEQNQIIRNDKAD
TLIIQGVAGSGKTSIALHRIAFLLYRFKDKISANNVIILSPNKVFGDYISNVLPELGEEPLCELSFENIAEVQLDRVINF
ESEKDPLEINDAKWSERVRFKSTLDFVKLIDDYIKQMPNKIFIPKDYTFGSFTAKSDWIQSRFEAYNRYPVKKRLEKVAE
DIHYKFESDNIMEEDLPKVKSILKSLNGMLTIKNTLTLYKDFFKQMNISNMFVMVEKKTLEWSDVYPFIYIHAAYEGIQE
DKIIRHIVIDEMQDYTPIQYAVINLLFKCKKTILGDFGQLVNPNHTHTLDDMKQLYNDGELVMLNKSYRSTFEIINFAKK
IQDISSLEPIERHGEEPALLKCNNEQDEINKIKIEIEEFKKSDNATLGIILKTDNDAKAVYDALREEYSVHLISSESSSF
TKGVSITSIKMSKGLEFDEVIVPSVNNKTYYSDYDHSLLYIACTRAMHKLKLTYVGTLTQLISM

Sequences:

>Translated_704_residues
MSENKQVVNCDIIASNSKHNMCEYDAELLTFFPDEIAHLIEINNKLDNAFKKAENLVDKLDKDYMDAKMYMVKNRGEIDP
HEMFQNEQGLKQIDNYGAFMVKVRGKINKIKDSPYFARIDFRLKDMDDESKYYIGRFAFDYEDELIILDWRSPIASMFYD
YEIGKAGYDAPIGWVDGEITRKRQFKIKNGKLEYALESSINIQDDILQKELSHTSDEKMKSIISTIQKEQNQIIRNDKAD
TLIIQGVAGSGKTSIALHRIAFLLYRFKDKISANNVIILSPNKVFGDYISNVLPELGEEPLCELSFENIAEVQLDRVINF
ESEKDPLEINDAKWSERVRFKSTLDFVKLIDDYIKQMPNKIFIPKDYTFGSFTAKSDWIQSRFEAYNRYPVKKRLEKVAE
DIHYKFESDNIMEEDLPKVKSILKSLNGMLTIKNTLTLYKDFFKQMNISNMFVMVEKKTLEWSDVYPFIYIHAAYEGIQE
DKIIRHIVIDEMQDYTPIQYAVINLLFKCKKTILGDFGQLVNPNHTHTLDDMKQLYNDGELVMLNKSYRSTFEIINFAKK
IQDISSLEPIERHGEEPALLKCNNEQDEINKIKIEIEEFKKSDNATLGIILKTDNDAKAVYDALREEYSVHLISSESSSF
TKGVSITSIKMSKGLEFDEVIVPSVNNKTYYSDYDHSLLYIACTRAMHKLKLTYVGTLTQLISM
>Mature_703_residues
SENKQVVNCDIIASNSKHNMCEYDAELLTFFPDEIAHLIEINNKLDNAFKKAENLVDKLDKDYMDAKMYMVKNRGEIDPH
EMFQNEQGLKQIDNYGAFMVKVRGKINKIKDSPYFARIDFRLKDMDDESKYYIGRFAFDYEDELIILDWRSPIASMFYDY
EIGKAGYDAPIGWVDGEITRKRQFKIKNGKLEYALESSINIQDDILQKELSHTSDEKMKSIISTIQKEQNQIIRNDKADT
LIIQGVAGSGKTSIALHRIAFLLYRFKDKISANNVIILSPNKVFGDYISNVLPELGEEPLCELSFENIAEVQLDRVINFE
SEKDPLEINDAKWSERVRFKSTLDFVKLIDDYIKQMPNKIFIPKDYTFGSFTAKSDWIQSRFEAYNRYPVKKRLEKVAED
IHYKFESDNIMEEDLPKVKSILKSLNGMLTIKNTLTLYKDFFKQMNISNMFVMVEKKTLEWSDVYPFIYIHAAYEGIQED
KIIRHIVIDEMQDYTPIQYAVINLLFKCKKTILGDFGQLVNPNHTHTLDDMKQLYNDGELVMLNKSYRSTFEIINFAKKI
QDISSLEPIERHGEEPALLKCNNEQDEINKIKIEIEEFKKSDNATLGIILKTDNDAKAVYDALREEYSVHLISSESSSFT
KGVSITSIKMSKGLEFDEVIVPSVNNKTYYSDYDHSLLYIACTRAMHKLKLTYVGTLTQLISM

Specific function: Catalyzes the unwinding of duplex DNA in the 3' to 5' direction; this reaction is dependent on the hydrolysis of ATP [H]

COG id: COG3973

COG function: function code R; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 81758; Mature: 81627

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENKQVVNCDIIASNSKHNMCEYDAELLTFFPDEIAHLIEINNKLDNAFKKAENLVDKL
CCCCCEEEEEEEEECCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DKDYMDAKMYMVKNRGEIDPHEMFQNEQGLKQIDNYGAFMVKVRGKINKIKDSPYFARID
CHHHHHHEEEEEECCCCCCHHHHHCCCCHHHHHHCCCEEEEEEECCHHCCCCCCEEEEEE
FRLKDMDDESKYYIGRFAFDYEDELIILDWRSPIASMFYDYEIGKAGYDAPIGWVDGEIT
EEEECCCCCCCEEEEEEEECCCCCEEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCCCCC
RKRQFKIKNGKLEYALESSINIQDDILQKELSHTSDEKMKSIISTIQKEQNQIIRNDKAD
CCEEEEEECCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCC
TLIIQGVAGSGKTSIALHRIAFLLYRFKDKISANNVIILSPNKVFGDYISNVLPELGEEP
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCC
LCELSFENIAEVQLDRVINFESEKDPLEINDAKWSERVRFKSTLDFVKLIDDYIKQMPNK
CHHCCHHHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCE
IFIPKDYTFGSFTAKSDWIQSRFEAYNRYPVKKRLEKVAEDIHYKFESDNIMEEDLPKVK
EECCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCEEECCCCCCHHHHHHHH
SILKSLNGMLTIKNTLTLYKDFFKQMNISNMFVMVEKKTLEWSDVYPFIYIHAAYEGIQE
HHHHHCCCEEEEHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCEEEEEEHHCCCCH
DKIIRHIVIDEMQDYTPIQYAVINLLFKCKKTILGDFGQLVNPNHTHTLDDMKQLYNDGE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCC
LVMLNKSYRSTFEIINFAKKIQDISSLEPIERHGEEPALLKCNNEQDEINKIKIEIEEFK
EEEEECHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEEECCCCCCCCEEEEEHHHHC
KSDNATLGIILKTDNDAKAVYDALREEYSVHLISSESSSFTKGVSITSIKMSKGLEFDEV
CCCCCEEEEEEECCCCHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCE
IVPSVNNKTYYSDYDHSLLYIACTRAMHKLKLTYVGTLTQLISM
EECCCCCCCEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SENKQVVNCDIIASNSKHNMCEYDAELLTFFPDEIAHLIEINNKLDNAFKKAENLVDKL
CCCCEEEEEEEEECCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DKDYMDAKMYMVKNRGEIDPHEMFQNEQGLKQIDNYGAFMVKVRGKINKIKDSPYFARID
CHHHHHHEEEEEECCCCCCHHHHHCCCCHHHHHHCCCEEEEEEECCHHCCCCCCEEEEEE
FRLKDMDDESKYYIGRFAFDYEDELIILDWRSPIASMFYDYEIGKAGYDAPIGWVDGEIT
EEEECCCCCCCEEEEEEEECCCCCEEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCCCCC
RKRQFKIKNGKLEYALESSINIQDDILQKELSHTSDEKMKSIISTIQKEQNQIIRNDKAD
CCEEEEEECCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCC
TLIIQGVAGSGKTSIALHRIAFLLYRFKDKISANNVIILSPNKVFGDYISNVLPELGEEP
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCC
LCELSFENIAEVQLDRVINFESEKDPLEINDAKWSERVRFKSTLDFVKLIDDYIKQMPNK
CHHCCHHHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCE
IFIPKDYTFGSFTAKSDWIQSRFEAYNRYPVKKRLEKVAEDIHYKFESDNIMEEDLPKVK
EECCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCEEECCCCCCHHHHHHHH
SILKSLNGMLTIKNTLTLYKDFFKQMNISNMFVMVEKKTLEWSDVYPFIYIHAAYEGIQE
HHHHHCCCEEEEHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCEEEEEEHHCCCCH
DKIIRHIVIDEMQDYTPIQYAVINLLFKCKKTILGDFGQLVNPNHTHTLDDMKQLYNDGE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCC
LVMLNKSYRSTFEIINFAKKIQDISSLEPIERHGEEPALLKCNNEQDEINKIKIEIEEFK
EEEEECHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEEECCCCCCCCEEEEEHHHHC
KSDNATLGIILKTDNDAKAVYDALREEYSVHLISSESSSFTKGVSITSIKMSKGLEFDEV
CCCCCEEEEEEECCCCHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCE
IVPSVNNKTYYSDYDHSLLYIACTRAMHKLKLTYVGTLTQLISM
EECCCCCCCEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]