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The map label for this gene is cisA [H]

Identifier: 126698008

GI number: 126698008

Start: 518036

End: 519802

Strand: Direct

Name: cisA [H]

Synonym: CD0436

Alternate gene names: 126698008

Gene position: 518036-519802 (Clockwise)

Preceding gene: 126698007

Following gene: 126698010

Centisome position: 12.07

GC content: 33.62

Gene sequence:

>1767_bases
GTGAAGAAAGATGTAAAAGTTATTAAAGGTGATACCACACTGAAAAGAACTGCATCAGGCTGTGTTGAACGCTCAATAAA
GCGAGTGGCAGCTTATTGCAGAGTTAGTACAGATACTGAAGATCAGATTAACAGCTATAATTCTCAAGTAGAACACTACA
CAGAATTTATACAGAAAAATAAAGAGTGGACTCTTGCTGGAATATATGCTGATGAAGCAATAACAGGAACACAGGTTGAT
CGAAGAATTGACTTTCAAAGGCTGATAAATGACTGTATGAATGGCGATATAGATATGATAATTACAAAGTCTATATCAAG
ATTTGCGAGAAATACATTAGACACTTTAAAGTATGTAAGAAAGTTAAAAGAGTTTAATGTTGCGGTATTTTTTGAAGAAG
AAAACATAAATACTCTAACAATGGATGGCGAATTGCTTTTGACTATTTTAAGTTCAGTTGCTCAACAGGAAGTAGAGAAC
ATTTCAGCTAATGTTAAAAAAGGCTTGAGAATGAAAATGGAAAGAGGAGAAATGGTCGGCTTTCAAGGATGTTTAGGTTA
TGACTATAATCCGGAGACAAAAAGCATTTCTGTAAACGAAAAAGAAGCTGAAATTGTAAGATATATTTTCAGAAGATATA
TTGAAGGCGTCGGTGGAATGGTAATCTCAAGAGAGTTGGAAGAACAGGGATATTTATCACCAAGAGGAAATAAAAGGTGG
ACTGAAACAACAGTTTTAGGAATTATAAAAAACGAGAAATATAAAGGGGATCTCATGATGGGAAAGACCTATACGGTTGA
TCCTATTTCAAAGAGAAGATTGGATAATTTTGGAGAACAGGATAAGTTTTATATAGAAAGCCATCACGAGCCAATTATTT
CGAAAGAAGATTTTGAAAAGGCTCAAGGCATTAGATTAAGAAGGTCAAAAAATAGAAATACCGTTGCTAACAATGGTGGT
AAAAGAGAAAAATATTCAAGAAAATATGCTTTTAGCAGCATGCTGGAATGCGGATTTTGCGGTCATAATCTTTCAAGAAG
AAATTGGCATTCAAGTTCAGAATATACAAAAGTGATATGGCAGTGTGTCAATGCTACTAAAAATGGGAAAAAGTATTGTC
CGCATAGCAAAGGAATTGAAGAAGCAGCTATAGAAAAAGCATTTATGGAAAGTTATCGTCAAGTATGCCACAATAATGTA
GAAATTACCAACGAATTCCTTAAAACTGTTGAAGAAGAATTGAAAGACAACAGTTTAGCTAAAGACTTGAAGAAGATAAG
CAATCAACTTGATAAAATAATAAAGAAAGAAAAAGATCTTGTTGAATTAAGGCTGAATGAGTCAATCAGCATGGATATAT
ATCAGGACAAGTATAATGAAATAGCCATTAGCAAAGAGAAATTACTTGCAGAAAAAAGGACTTTAGAAGTAACACTTACT
GATGAAAAAGCATTGAAGAAAAGGCTTGAGGGTTTTAAAAAATTACTTGAATCCAATAAATACCTTGAGGAATTTGATAG
AGCTGTATTTGAAAGTATAGTAGATAAAATCATTATTGGGGGAACTAACGATGAAGGCGAAATTGATCCTGCAATGATTA
CTATCATATACAAGACCGGGAAAAAAGATTCTCAGGACGGGAGATTATTTAAGAGCAGAAGAAAAAATGCCAAGGAAGTT
AATGAGGAAACTGGCGGCAAATTGTATCCTCAATCAAGCGACGAGGTTAATAATTTGTATTCCTATCCTATTGACAACAC
ATTGTGA

Upstream 100 bases:

>100_bases
ATGAAAAAGTATAACATTTTGACAGAATTATATTTATAATGTTTTGTAAGTGTGGTATAATTAGACTGCATAGAAAGATA
CAAATAAGGAGGCGGATGCA

Downstream 100 bases:

>100_bases
GACTGTAGTTAAACTTATTAGAGAATAACAGGGTTTCAGACTTTTATATTGTGTCTTAAAAGTAGATTTGCCACCTATTT
GCCACCATAATTATTTTTGG

Product: recombinase

Products: NA

Alternate protein names: Stage IV sporulation protein CA [H]

Number of amino acids: Translated: 588; Mature: 588

Protein sequence:

>588_residues
MKKDVKVIKGDTTLKRTASGCVERSIKRVAAYCRVSTDTEDQINSYNSQVEHYTEFIQKNKEWTLAGIYADEAITGTQVD
RRIDFQRLINDCMNGDIDMIITKSISRFARNTLDTLKYVRKLKEFNVAVFFEEENINTLTMDGELLLTILSSVAQQEVEN
ISANVKKGLRMKMERGEMVGFQGCLGYDYNPETKSISVNEKEAEIVRYIFRRYIEGVGGMVISRELEEQGYLSPRGNKRW
TETTVLGIIKNEKYKGDLMMGKTYTVDPISKRRLDNFGEQDKFYIESHHEPIISKEDFEKAQGIRLRRSKNRNTVANNGG
KREKYSRKYAFSSMLECGFCGHNLSRRNWHSSSEYTKVIWQCVNATKNGKKYCPHSKGIEEAAIEKAFMESYRQVCHNNV
EITNEFLKTVEEELKDNSLAKDLKKISNQLDKIIKKEKDLVELRLNESISMDIYQDKYNEIAISKEKLLAEKRTLEVTLT
DEKALKKRLEGFKKLLESNKYLEEFDRAVFESIVDKIIIGGTNDEGEIDPAMITIIYKTGKKDSQDGRLFKSRRKNAKEV
NEETGGKLYPQSSDEVNNLYSYPIDNTL

Sequences:

>Translated_588_residues
MKKDVKVIKGDTTLKRTASGCVERSIKRVAAYCRVSTDTEDQINSYNSQVEHYTEFIQKNKEWTLAGIYADEAITGTQVD
RRIDFQRLINDCMNGDIDMIITKSISRFARNTLDTLKYVRKLKEFNVAVFFEEENINTLTMDGELLLTILSSVAQQEVEN
ISANVKKGLRMKMERGEMVGFQGCLGYDYNPETKSISVNEKEAEIVRYIFRRYIEGVGGMVISRELEEQGYLSPRGNKRW
TETTVLGIIKNEKYKGDLMMGKTYTVDPISKRRLDNFGEQDKFYIESHHEPIISKEDFEKAQGIRLRRSKNRNTVANNGG
KREKYSRKYAFSSMLECGFCGHNLSRRNWHSSSEYTKVIWQCVNATKNGKKYCPHSKGIEEAAIEKAFMESYRQVCHNNV
EITNEFLKTVEEELKDNSLAKDLKKISNQLDKIIKKEKDLVELRLNESISMDIYQDKYNEIAISKEKLLAEKRTLEVTLT
DEKALKKRLEGFKKLLESNKYLEEFDRAVFESIVDKIIIGGTNDEGEIDPAMITIIYKTGKKDSQDGRLFKSRRKNAKEV
NEETGGKLYPQSSDEVNNLYSYPIDNTL
>Mature_588_residues
MKKDVKVIKGDTTLKRTASGCVERSIKRVAAYCRVSTDTEDQINSYNSQVEHYTEFIQKNKEWTLAGIYADEAITGTQVD
RRIDFQRLINDCMNGDIDMIITKSISRFARNTLDTLKYVRKLKEFNVAVFFEEENINTLTMDGELLLTILSSVAQQEVEN
ISANVKKGLRMKMERGEMVGFQGCLGYDYNPETKSISVNEKEAEIVRYIFRRYIEGVGGMVISRELEEQGYLSPRGNKRW
TETTVLGIIKNEKYKGDLMMGKTYTVDPISKRRLDNFGEQDKFYIESHHEPIISKEDFEKAQGIRLRRSKNRNTVANNGG
KREKYSRKYAFSSMLECGFCGHNLSRRNWHSSSEYTKVIWQCVNATKNGKKYCPHSKGIEEAAIEKAFMESYRQVCHNNV
EITNEFLKTVEEELKDNSLAKDLKKISNQLDKIIKKEKDLVELRLNESISMDIYQDKYNEIAISKEKLLAEKRTLEVTLT
DEKALKKRLEGFKKLLESNKYLEEFDRAVFESIVDKIIIGGTNDEGEIDPAMITIIYKTGKKDSQDGRLFKSRRKNAKEV
NEETGGKLYPQSSDEVNNLYSYPIDNTL

Specific function: Putative site-specific recombinase having a very important role in sporulation. It probably plays a role in the recombination of spoIIIC and spoIVCB to form sigma K factor [H]

COG id: COG1961

COG function: function code L; Site-specific recombinases, DNA invertase Pin homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 recombinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011109
- InterPro:   IPR006118
- InterPro:   IPR006119 [H]

Pfam domain/function: PF07508 Recombinase; PF00239 Resolvase [H]

EC number: NA

Molecular weight: Translated: 67878; Mature: 67878

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKDVKVIKGDTTLKRTASGCVERSIKRVAAYCRVSTDTEDQINSYNSQVEHYTEFIQKN
CCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
KEWTLAGIYADEAITGTQVDRRIDFQRLINDCMNGDIDMIITKSISRFARNTLDTLKYVR
CCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHH
KLKEFNVAVFFEEENINTLTMDGELLLTILSSVAQQEVENISANVKKGLRMKMERGEMVG
HHHHCCEEEEEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEC
FQGCLGYDYNPETKSISVNEKEAEIVRYIFRRYIEGVGGMVISRELEEQGYLSPRGNKRW
CCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCC
TETTVLGIIKNEKYKGDLMMGKTYTVDPISKRRLDNFGEQDKFYIESHHEPIISKEDFEK
HHHHEEEEEECCCCCCCEEECCEEECCCHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHH
AQGIRLRRSKNRNTVANNGGKREKYSRKYAFSSMLECGFCGHNLSRRNWHSSSEYTKVIW
HHCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
QCVNATKNGKKYCPHSKGIEEAAIEKAFMESYRQVCHNNVEITNEFLKTVEEELKDNSLA
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHH
KDLKKISNQLDKIIKKEKDLVELRLNESISMDIYQDKYNEIAISKEKLLAEKRTLEVTLT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHCCHHHHHHHHHHHHHHHHEEEEEEC
DEKALKKRLEGFKKLLESNKYLEEFDRAVFESIVDKIIIGGTNDEGEIDPAMITIIYKTG
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEEEECC
KKDSQDGRLFKSRRKNAKEVNEETGGKLYPQSSDEVNNLYSYPIDNTL
CCCCCCHHHHHHHCCCHHHHHHHCCCEECCCCCHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKKDVKVIKGDTTLKRTASGCVERSIKRVAAYCRVSTDTEDQINSYNSQVEHYTEFIQKN
CCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
KEWTLAGIYADEAITGTQVDRRIDFQRLINDCMNGDIDMIITKSISRFARNTLDTLKYVR
CCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHH
KLKEFNVAVFFEEENINTLTMDGELLLTILSSVAQQEVENISANVKKGLRMKMERGEMVG
HHHHCCEEEEEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEC
FQGCLGYDYNPETKSISVNEKEAEIVRYIFRRYIEGVGGMVISRELEEQGYLSPRGNKRW
CCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCC
TETTVLGIIKNEKYKGDLMMGKTYTVDPISKRRLDNFGEQDKFYIESHHEPIISKEDFEK
HHHHEEEEEECCCCCCCEEECCEEECCCHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHH
AQGIRLRRSKNRNTVANNGGKREKYSRKYAFSSMLECGFCGHNLSRRNWHSSSEYTKVIW
HHCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
QCVNATKNGKKYCPHSKGIEEAAIEKAFMESYRQVCHNNVEITNEFLKTVEEELKDNSLA
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHH
KDLKKISNQLDKIIKKEKDLVELRLNESISMDIYQDKYNEIAISKEKLLAEKRTLEVTLT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHCCHHHHHHHHHHHHHHHHEEEEEEC
DEKALKKRLEGFKKLLESNKYLEEFDRAVFESIVDKIIIGGTNDEGEIDPAMITIIYKTG
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEEEECC
KKDSQDGRLFKSRRKNAKEVNEETGGKLYPQSSDEVNNLYSYPIDNTL
CCCCCCHHHHHHHCCCHHHHHHHCCCEECCCCCHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2105293; 7704261; 8969508; 9384377 [H]