Click here to switch to the map view.

The map label for this gene is tetD [H]

Identifier: 126697848

GI number: 126697848

Start: 338303

End: 339214

Strand: Direct

Name: tetD [H]

Synonym: CD0276

Alternate gene names: 126697848

Gene position: 338303-339214 (Clockwise)

Preceding gene: 126697847

Following gene: 126697849

Centisome position: 7.89

GC content: 32.46

Gene sequence:

>912_bases
ATGCATGCATGGGAGTCTATTCAAATTACATTGGATTTAATAGAAGCAAATTTATCAGAAGAAATATCAATTAATGAATT
AGCAAATAAAGCAAATTTATCACCATTTTACTATCAAAGACTATTTAAAAGATTGGTAAATAAGACTGTAATGGAGTATA
TAAAGCTTCGTCGTCTTGCAAGAGCTTCTGAATACTTAGCAGAACATAAGAATCGTATACTTGATGTAGCTTTAAATTTT
GGATTTGCTAGTCATGAGACATTTACACGTTCCTTTAAAAAAGCATATGGATTAACTCCAGAAAAATATAGAGCAAATCC
AGTAAAACTCAATCACTTTATTAAGCCAGAATTAATTTTAAATTATGCTATGGTTGATGAAGGTGTTCCACTGATTGCAG
ATGATATAGTGATTGAAGTTAATCGTAAGACATTGAGTAATCCAAGGACATTTGTTGGAATAGAAATAGAAGTACCTATT
TGCCAGTTGGTAGGCGGTGAAACAACTGGAATTGCAATAGTAGAGGAATTATGGATGAAACTTGGAAGTCAAAGACATAA
TATACCAAATCAAATTCCAGGTGGAAATGAATTTGCTGCTCTTTATATGGGAAATGCAAAAGAAGGAAATTGTATGTATA
TGGCAGGTGTAGAGGTAGAGTCAGGTACATCAGTAGAAGGATATAGTACTTTTGAGTTGCCAGTTAAAGAATATTTAGTA
TGTGGATTTGAGGCAGAAAACTTTAATGAGTTAGTTAATTCAGCTGTTTTTAAAGCAGATAAATTTATGGAAAGATGGAT
GAAGAAACATAATTTAACAACTACTGATTTTGCAATTGAGATGTATTACCCCACTACACCTGAAGCAGCATATCTGGAAC
ATTGGATTGTTCCGGTTCCTATTGAACAATAG

Upstream 100 bases:

>100_bases
TATAAGAAAATTAAAAAGGGCACTATCTATCAAGAACATTTTTTCTAGTTTTGATACTATAAAGGATAAGAGTAACAAAA
ATATCAGGAGGAGTTATAGT

Downstream 100 bases:

>100_bases
AAAGGATGATGAATATGAATTGGCAAGATGCGTTTTTTCAAGATACTAAACCTACATTTGAGCAAATTAATGAATTTATT
AATAATCCATTATGGGACAA

Product: AraC family transcription regulator

Products: NA

Alternate protein names: ORFR [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MHAWESIQITLDLIEANLSEEISINELANKANLSPFYYQRLFKRLVNKTVMEYIKLRRLARASEYLAEHKNRILDVALNF
GFASHETFTRSFKKAYGLTPEKYRANPVKLNHFIKPELILNYAMVDEGVPLIADDIVIEVNRKTLSNPRTFVGIEIEVPI
CQLVGGETTGIAIVEELWMKLGSQRHNIPNQIPGGNEFAALYMGNAKEGNCMYMAGVEVESGTSVEGYSTFELPVKEYLV
CGFEAENFNELVNSAVFKADKFMERWMKKHNLTTTDFAIEMYYPTTPEAAYLEHWIVPVPIEQ

Sequences:

>Translated_303_residues
MHAWESIQITLDLIEANLSEEISINELANKANLSPFYYQRLFKRLVNKTVMEYIKLRRLARASEYLAEHKNRILDVALNF
GFASHETFTRSFKKAYGLTPEKYRANPVKLNHFIKPELILNYAMVDEGVPLIADDIVIEVNRKTLSNPRTFVGIEIEVPI
CQLVGGETTGIAIVEELWMKLGSQRHNIPNQIPGGNEFAALYMGNAKEGNCMYMAGVEVESGTSVEGYSTFELPVKEYLV
CGFEAENFNELVNSAVFKADKFMERWMKKHNLTTTDFAIEMYYPTTPEAAYLEHWIVPVPIEQ
>Mature_303_residues
MHAWESIQITLDLIEANLSEEISINELANKANLSPFYYQRLFKRLVNKTVMEYIKLRRLARASEYLAEHKNRILDVALNF
GFASHETFTRSFKKAYGLTPEKYRANPVKLNHFIKPELILNYAMVDEGVPLIADDIVIEVNRKTLSNPRTFVGIEIEVPI
CQLVGGETTGIAIVEELWMKLGSQRHNIPNQIPGGNEFAALYMGNAKEGNCMYMAGVEVESGTSVEGYSTFELPVKEYLV
CGFEAENFNELVNSAVFKADKFMERWMKKHNLTTTDFAIEMYYPTTPEAAYLEHWIVPVPIEQ

Specific function: Binds To The Right Arm Of The Replication Origin Oric Of The E.Coli Chromosome. Rob Binding May Influence The Formation Of The Nucleoprotein Structure, Required For Oric Function In The Initiation Of Replication. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790857, Length=137, Percent_Identity=33.5766423357664, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790497, Length=98, Percent_Identity=32.6530612244898, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87081928, Length=116, Percent_Identity=31.0344827586207, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790559, Length=103, Percent_Identity=31.0679611650485, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 34604; Mature: 34604

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAWESIQITLDLIEANLSEEISINELANKANLSPFYYQRLFKRLVNKTVMEYIKLRRLA
CCCCCEEEEEEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RASEYLAEHKNRILDVALNFGFASHETFTRSFKKAYGLTPEKYRANPVKLNHFIKPELIL
HHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHCCCHHHHCCCCEEECCCCCHHHHH
NYAMVDEGVPLIADDIVIEVNRKTLSNPRTFVGIEIEVPICQLVGGETTGIAIVEELWMK
HHHHHCCCCCEEECCEEEEECCHHCCCCCEEEEEEEECCHHHHCCCCCCHHHHHHHHHHH
LGSQRHNIPNQIPGGNEFAALYMGNAKEGNCMYMAGVEVESGTSVEGYSTFELPVKEYLV
HCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEEECCCCCCCCCEEEECCHHHHEE
CGFEAENFNELVNSAVFKADKFMERWMKKHNLTTTDFAIEMYYPTTPEAAYLEHWIVPVP
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCHHHHHHCEEECC
IEQ
CCC
>Mature Secondary Structure
MHAWESIQITLDLIEANLSEEISINELANKANLSPFYYQRLFKRLVNKTVMEYIKLRRLA
CCCCCEEEEEEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RASEYLAEHKNRILDVALNFGFASHETFTRSFKKAYGLTPEKYRANPVKLNHFIKPELIL
HHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHCCCHHHHCCCCEEECCCCCHHHHH
NYAMVDEGVPLIADDIVIEVNRKTLSNPRTFVGIEIEVPICQLVGGETTGIAIVEELWMK
HHHHHCCCCCEEECCEEEEECCHHCCCCCEEEEEEEECCHHHHCCCCCCHHHHHHHHHHH
LGSQRHNIPNQIPGGNEFAALYMGNAKEGNCMYMAGVEVESGTSVEGYSTFELPVKEYLV
HCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEEECCCCCCCCCEEEECCHHHHEE
CGFEAENFNELVNSAVFKADKFMERWMKKHNLTTTDFAIEMYYPTTPEAAYLEHWIVPVP
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCHHHHHHCEEECC
IEQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6094471; 6094472 [H]