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The map label for this gene is flhF [H]

Identifier: 126697836

GI number: 126697836

Start: 325776

End: 326792

Strand: Direct

Name: flhF [H]

Synonym: CD0264

Alternate gene names: 126697836

Gene position: 325776-326792 (Clockwise)

Preceding gene: 126697835

Following gene: 126697837

Centisome position: 7.59

GC content: 27.53

Gene sequence:

>1017_bases
ATGATGACGAAAAAGTATACAGCTAACACAATTCAGGATGCTATGAATCTAGCCAAAATGGAATTGGGTGACAATATTAC
ATTAATAGATAAAAAAGAAGTAAGAAAGTCTGGAATACAAGGTATCTTTTCAAAGAAAGATATTGAACTAACTATTGGAT
GGGAAAAGAGAGAAAACGTAGAACAAAAAGATTTAAAACGAGAGATAGAACAATTAAAGTCAATTATTAACAATATGGGG
TTTGATAATAAGAATGATAATGATATAGATAAAATATGTAAAAATCTACTAAGTTTAGAATTGAATGAAGAAATTGTAGA
ATCTATAAGAATTGATTTGCAAGAAATGAAGTTCAATGGAATCGATACAAGTAAAAATTTAGTAGAAATTTTAAAGAAAA
AGATTAAAATAGAAAATCAAGTAATAAATGGTAAAATTGCTCTAGTCGGACCACCAGGAGTAGGTAAAACGACTACAATA
GCAAAGTTAGCCGCAAAATTAGTTTTTGAAGAAAATAAAAAAGTAGGAGTAATAACTATAGATACATACAGGATTGGTGC
TGTAGAACAGTTGAAGATATATACTGATATAATGAATATTCCCTTTAAAGGGGTAATAAGTCCTGATGAAATGGAATTGG
CACTTGACGAGATGAAAGATTGTGATGTTGTATTAATAGATACAACAGGTAGAGGCTACAAAAACTCTATGCAAATACTA
GAAATCAAAAATCTTATAGATAAAGCTGAAACTGATAATATACATTTAGTTTTGAATTGTACAACAAGAGAAAGTGATAC
AAAAGCAATTATAGATTCATATAGAAATGTGAATTTTAAAAGCTTAATAATTACAAAGCTAGATGAAACAATAACATATG
GCTCAATATTTAACATAATGAATTATGCACAAAAACCAATATCATATATTACAACAGGACAAAATGTTCCTGATGATATT
ATAAAACCTAATGAAGATAAGATTATAAGGTTACTATTAGGAGTTGAAAGTATATGA

Upstream 100 bases:

>100_bases
AGAAAATTAGTTGAAATTGTATATCCTAATTTGACTGTATTATCATTAAATGAAATACCTAACGATATTAAAATCAAAGC
AGAAGGTGTGGTGAGCATAT

Downstream 100 bases:

>100_bases
TAGACCAAGCTCAAATTTTGAGAAAAATAGCAATGGAAAAAAGAGGACTTGATGAGTTTATAGTAGAGAATGAGAATGTA
CCTAAGATAATTACAATAGC

Product: flagellar biosynthesis regulator FlhF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MMTKKYTANTIQDAMNLAKMELGDNITLIDKKEVRKSGIQGIFSKKDIELTIGWEKRENVEQKDLKREIEQLKSIINNMG
FDNKNDNDIDKICKNLLSLELNEEIVESIRIDLQEMKFNGIDTSKNLVEILKKKIKIENQVINGKIALVGPPGVGKTTTI
AKLAAKLVFEENKKVGVITIDTYRIGAVEQLKIYTDIMNIPFKGVISPDEMELALDEMKDCDVVLIDTTGRGYKNSMQIL
EIKNLIDKAETDNIHLVLNCTTRESDTKAIIDSYRNVNFKSLIITKLDETITYGSIFNIMNYAQKPISYITTGQNVPDDI
IKPNEDKIIRLLLGVESI

Sequences:

>Translated_338_residues
MMTKKYTANTIQDAMNLAKMELGDNITLIDKKEVRKSGIQGIFSKKDIELTIGWEKRENVEQKDLKREIEQLKSIINNMG
FDNKNDNDIDKICKNLLSLELNEEIVESIRIDLQEMKFNGIDTSKNLVEILKKKIKIENQVINGKIALVGPPGVGKTTTI
AKLAAKLVFEENKKVGVITIDTYRIGAVEQLKIYTDIMNIPFKGVISPDEMELALDEMKDCDVVLIDTTGRGYKNSMQIL
EIKNLIDKAETDNIHLVLNCTTRESDTKAIIDSYRNVNFKSLIITKLDETITYGSIFNIMNYAQKPISYITTGQNVPDDI
IKPNEDKIIRLLLGVESI
>Mature_338_residues
MMTKKYTANTIQDAMNLAKMELGDNITLIDKKEVRKSGIQGIFSKKDIELTIGWEKRENVEQKDLKREIEQLKSIINNMG
FDNKNDNDIDKICKNLLSLELNEEIVESIRIDLQEMKFNGIDTSKNLVEILKKKIKIENQVINGKIALVGPPGVGKTTTI
AKLAAKLVFEENKKVGVITIDTYRIGAVEQLKIYTDIMNIPFKGVISPDEMELALDEMKDCDVVLIDTTGRGYKNSMQIL
EIKNLIDKAETDNIHLVLNCTTRESDTKAIIDSYRNVNFKSLIITKLDETITYGSIFNIMNYAQKPISYITTGQNVPDDI
IKPNEDKIIRLLLGVESI

Specific function: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum [H]

COG id: COG1419

COG function: function code N; Flagellar GTP-binding protein

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=279, Percent_Identity=28.673835125448, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI226371618, Length=249, Percent_Identity=29.3172690763052, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1789874, Length=204, Percent_Identity=29.9019607843137, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788963, Length=214, Percent_Identity=26.1682242990654, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17539958, Length=200, Percent_Identity=28.5, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6325345, Length=205, Percent_Identity=30.7317073170732, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17647949, Length=279, Percent_Identity=30.1075268817204, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR020006 [H]

Pfam domain/function: PF00448 SRP54 [H]

EC number: NA

Molecular weight: Translated: 38277; Mature: 38277

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTKKYTANTIQDAMNLAKMELGDNITLIDKKEVRKSGIQGIFSKKDIELTIGWEKRENV
CCCCCCCHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHCCCCCCEEEEECCCHHCCC
EQKDLKREIEQLKSIINNMGFDNKNDNDIDKICKNLLSLELNEEIVESIRIDLQEMKFNG
CHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC
IDTSKNLVEILKKKIKIENQVINGKIALVGPPGVGKTTTIAKLAAKLVFEENKKVGVITI
CCCHHHHHHHHHHHHHHHCEEECCEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEEE
DTYRIGAVEQLKIYTDIMNIPFKGVISPDEMELALDEMKDCDVVLIDTTGRGYKNSMQIL
ECEECCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHH
EIKNLIDKAETDNIHLVLNCTTRESDTKAIIDSYRNVNFKSLIITKLDETITYGSIFNIM
HHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHH
NYAQKPISYITTGQNVPDDIIKPNEDKIIRLLLGVESI
HHHHCCHHEEECCCCCCHHHCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MMTKKYTANTIQDAMNLAKMELGDNITLIDKKEVRKSGIQGIFSKKDIELTIGWEKRENV
CCCCCCCHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHCCCCCCEEEEECCCHHCCC
EQKDLKREIEQLKSIINNMGFDNKNDNDIDKICKNLLSLELNEEIVESIRIDLQEMKFNG
CHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC
IDTSKNLVEILKKKIKIENQVINGKIALVGPPGVGKTTTIAKLAAKLVFEENKKVGVITI
CCCHHHHHHHHHHHHHHHCEEECCEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEEE
DTYRIGAVEQLKIYTDIMNIPFKGVISPDEMELALDEMKDCDVVLIDTTGRGYKNSMQIL
ECEECCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHH
EIKNLIDKAETDNIHLVLNCTTRESDTKAIIDSYRNVNFKSLIITKLDETITYGSIFNIM
HHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHH
NYAQKPISYITTGQNVPDDIIKPNEDKIIRLLLGVESI
HHHHCCHHEEECCCCCCHHHCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]