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The map label for this gene is nrdD [H]

Identifier: 126697679

GI number: 126697679

Start: 138020

End: 140371

Strand: Direct

Name: nrdD [H]

Synonym: CD0108

Alternate gene names: 126697679

Gene position: 138020-140371 (Clockwise)

Preceding gene: 126697677

Following gene: 126697680

Centisome position: 3.22

GC content: 30.19

Gene sequence:

>2352_bases
TTGGTTGAATTCGTAAAAAAAAGAGATGGAAGAGTAATTCCATTTAATGAAGATAGAATAACAAGAGCTATATTTTTAGC
AGCAACGAATGTTGCAGAAAGAGAAGGAATAGTACCTGATTATAAATTATCTGAGCAATTAACTCAAGAAGTAATAAAGT
TTTTAAATCATAAATACTCAGAATCAGTTCCAAGTGTTGAAGATATACAAGATTCTGTAGTTAAGGTTCTTATAGAAACT
GGCCATGCAAAAACTAGTGAAGAATATATAATATACAGAACTGAAAGAAGTAGAATAAGAAATTCAAAAACAAGATTGAT
GAAGGCAATAGAGGAAATTACCTTTGAAGATGCAGAAGATGCTGATATAAAAAGAGAAAATGCAAATATTAATGGTAATA
CAGCAATGGGAACTATGTTACAATATGGAAGCACTGTATCTAAAGAATTTTGTAAAACACATATATTAAAACCAGAACAT
TCTTTTGCTCATGATAATGGAGATATACACATACATGATATGGATTTTTTAAATATGGGAACATTAACTTGTTGTCAAAT
AGATGTTAAAAAACTATTCAATGGTGGATTTTCAACAGGACATGGCTTTTTAAGAGAGCCACAAGATATAATAAGTTATG
GTGCATTAGCTGCAATTGCTATACAAAGCAATCAAAACGATCAACATGGAGGTCAAAGTATACCATTTTTCGATTATGGA
TTGGCTGAAGGTGTATATAAGACATTTAAGAAATTCTACATAGGAAATTTAGCTAAAGCATTGAAGTTATTTAAAGGAAT
TGAAAATAATGATGTGATAAAGAACATAGTATATAATACAGAGAAAGAAACAAATCAAAAAGTTGGTCTTAAGAGAGATG
AATTGTATCTAAACTTAGAAAAAGAGAAATTAATACAGACTTTTGATATAGATGATGAACTTGTAAATAAGATGCAAAAC
TTTGCATTTGAAGAATCGTATAGAGAAACTGATAAAAAAACATATCAATCTATGGAAGCATTTATACACAATCTAAACAC
AATGCACTCTAGAGCAGGTGCACAGGTACCATTTTCAAGTGTAAACTTCGGAACAGATACTTCTGAAGAAGGAAGAATGG
TAACTAAGAATCTTCTATTATCTCAAGAAAGAGGTTTAGGTAATGGAGAGACACCAATTTTTCCAATTTTAATATTTAAG
GTCAAAGAAGGCATAAATTTAAATCCTGAAGACCCTAATTATGATTTATTTAAATTATCATGCAGAGTATCAGCTAAAAG
ACTATTCCCTAATTTTAGTTTTTTAGATGCGCCTTTTAATGCAAAATATTATAAAAAAGGTGAACCAGATACAGAGGCTA
CATATATGGGTTGTAGAACAAGAGTACTTAGTAATGTGTGTGGTTCAGAAACAGTTAGTGGTAGAGGAAACATATCTTTT
ACTACAGTAAATTTACCAAGATTGGGTATAAAACATGGTATTATAAATAATGAAAAGGCTAATTTAGATGGTTTCTTTGA
AGAATTAGATGAGAAAATAAACTTAATTATAGAACAATTATTGGAGCGCCTTGAGGTACAAGGAAATAAAAAGATGAAGA
ATTTTCCATTCTTAATGGGGCAAGGTGTATGGAAAGGTTCTGATGATTTAGGACCAGAAGATACACTAAAAGAAGTAATA
AAACAAGGAACATTGACAATTGGATTTATAGGTTTAGCAGAGTGCCTTATTGCTCTTATAGGTAAACATCATGGAGAAAG
TAAAGAAGCTCAAGAATTAGGATTAAAAATAGTGTCACATATGAGACATAAAATGGATGAAGCAACGGACAAATATAAAT
TAAATTTCTCCTTAATGGGTACTCCAGCAGAAGGTCTTTCAGGTAGGTTTACTAAAATAGATAAAAAAGTTTATGGAGAA
ATTAAAGGTATCACAGATAAAGAATATTATACTAATTCATTCCATGTACCAGTTTATTACAATATAAGTGCATATGATAA
AATTGAGATAGAAGCTCCATACCATGAATTGACTAATGCAGGTCATATAACATATGTAGAGTTAGATGGAGATCCATCTG
ATAATTTAGAAGCTTTTGAAACTGTTATAAAAGCTATGAAAGATTTGGGTATAGGATATGGAAGTATAAATCATCCTGTA
GATAGAGACCCAATATGCGGTTTTTCAGGTGTAATAACAAGTAATATATGCCCTGTATGTGGAAGAAATGAAGATGAAAG
TGACATCAAATTCGAAAGAATAAGAAGAATAACAGGATACTTAGTTGGTACAGTTGATAGATTTAATAATGCTAAAAAAG
CAGAAGTAAGAGATAGAGTAAAACATAGATAG

Upstream 100 bases:

>100_bases
TTTAACTTAGTTGAAGGGGATTTTTTTAGACTTAACATACTACATATAGTGGTATGGGGATTAATAAAATACAATATATA
GTAACAGGAGGTTTTTTTAA

Downstream 100 bases:

>100_bases
TTTTATTTGGGGGAATAAGTTATGAAAATAAGAATGTCATCTACTATAAGTTATGACAGCATAGTTGATGGACCAGGATT
AAGAATGGTAATATGGACTC

Product: anaerobic ribonucleoside triphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 783; Mature: 783

Protein sequence:

>783_residues
MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLSEQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIET
GHAKTSEEYIIYRTERSRIRNSKTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEH
SFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAAIAIQSNQNDQHGGQSIPFFDYG
LAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNIVYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDDELVNKMQN
FAFEESYRETDKKTYQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETPIFPILIFK
VKEGINLNPEDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPDTEATYMGCRTRVLSNVCGSETVSGRGNISF
TTVNLPRLGIKHGIINNEKANLDGFFEELDEKINLIIEQLLERLEVQGNKKMKNFPFLMGQGVWKGSDDLGPEDTLKEVI
KQGTLTIGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRHKMDEATDKYKLNFSLMGTPAEGLSGRFTKIDKKVYGE
IKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGHITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPV
DRDPICGFSGVITSNICPVCGRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR

Sequences:

>Translated_783_residues
MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLSEQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIET
GHAKTSEEYIIYRTERSRIRNSKTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEH
SFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAAIAIQSNQNDQHGGQSIPFFDYG
LAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNIVYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDDELVNKMQN
FAFEESYRETDKKTYQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETPIFPILIFK
VKEGINLNPEDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPDTEATYMGCRTRVLSNVCGSETVSGRGNISF
TTVNLPRLGIKHGIINNEKANLDGFFEELDEKINLIIEQLLERLEVQGNKKMKNFPFLMGQGVWKGSDDLGPEDTLKEVI
KQGTLTIGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRHKMDEATDKYKLNFSLMGTPAEGLSGRFTKIDKKVYGE
IKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGHITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPV
DRDPICGFSGVITSNICPVCGRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR
>Mature_783_residues
MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLSEQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIET
GHAKTSEEYIIYRTERSRIRNSKTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEH
SFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAAIAIQSNQNDQHGGQSIPFFDYG
LAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNIVYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDDELVNKMQN
FAFEESYRETDKKTYQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETPIFPILIFK
VKEGINLNPEDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPDTEATYMGCRTRVLSNVCGSETVSGRGNISF
TTVNLPRLGIKHGIINNEKANLDGFFEELDEKINLIIEQLLERLEVQGNKKMKNFPFLMGQGVWKGSDDLGPEDTLKEVI
KQGTLTIGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRHKMDEATDKYKLNFSLMGTPAEGLSGRFTKIDKKVYGE
IKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGHITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPV
DRDPICGFSGVITSNICPVCGRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR

Specific function: Unknown

COG id: COG1328

COG function: function code F; Oxygen-sensitive ribonucleoside-triphosphate reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glycine radical domain [H]

Homologues:

Organism=Escherichia coli, GI1790686, Length=795, Percent_Identity=29.0566037735849, Blast_Score=298, Evalue=1e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR001150
- InterPro:   IPR019777
- InterPro:   IPR012833 [H]

Pfam domain/function: PF03477 ATP-cone; PF01228 Gly_radical [H]

EC number: =1.17.4.2 [H]

Molecular weight: Translated: 88580; Mature: 88580

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLSEQLTQEVIKFLNHKYS
CCCCHHCCCCEEECCCCCHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
ESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNSKTRLMKAIEEITFEDAED
CCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCC
ADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEHSFAHDNGDIHIHDMDFLNMG
CCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCC
TLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAAIAIQSNQNDQHGGQSIPFFDYG
CEEEHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCEEEEEEECCCCCCCCCCCCCCHHHH
LAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNIVYNTEKETNQKVGLKRDELYLNLE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHCCHHCCCEECCEEEEEC
KEKLIQTFDIDDELVNKMQNFAFEESYRETDKKTYQSMEAFIHNLNTMHSRAGAQVPFSS
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
VNFGTDTSEEGRMVTKNLLLSQERGLGNGETPIFPILIFKVKEGINLNPEDPNYDLFKLS
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCEEEEE
CRVSAKRLFPNFSFLDAPFNAKYYKKGEPDTEATYMGCRTRVLSNVCGSETVSGRGNISF
EEHHHHHHCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
TTVNLPRLGIKHGIINNEKANLDGFFEELDEKINLIIEQLLERLEVQGNKKMKNFPFLMG
EEEECCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEC
QGVWKGSDDLGPEDTLKEVIKQGTLTIGFIGLAECLIALIGKHHGESKEAQELGLKIVSH
CCCCCCCCCCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
MRHKMDEATDKYKLNFSLMGTPAEGLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYY
HHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEE
NISAYDKIEIEAPYHELTNAGHITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPV
ECCCCCEEEEECCHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
DRDPICGFSGVITSNICPVCGRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRV
CCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
KHR
CCC
>Mature Secondary Structure
MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLSEQLTQEVIKFLNHKYS
CCCCHHCCCCEEECCCCCHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
ESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNSKTRLMKAIEEITFEDAED
CCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCC
ADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEHSFAHDNGDIHIHDMDFLNMG
CCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCC
TLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAAIAIQSNQNDQHGGQSIPFFDYG
CEEEHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCEEEEEEECCCCCCCCCCCCCCHHHH
LAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNIVYNTEKETNQKVGLKRDELYLNLE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHCCHHCCCEECCEEEEEC
KEKLIQTFDIDDELVNKMQNFAFEESYRETDKKTYQSMEAFIHNLNTMHSRAGAQVPFSS
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
VNFGTDTSEEGRMVTKNLLLSQERGLGNGETPIFPILIFKVKEGINLNPEDPNYDLFKLS
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCEEEEE
CRVSAKRLFPNFSFLDAPFNAKYYKKGEPDTEATYMGCRTRVLSNVCGSETVSGRGNISF
EEHHHHHHCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
TTVNLPRLGIKHGIINNEKANLDGFFEELDEKINLIIEQLLERLEVQGNKKMKNFPFLMG
EEEECCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEC
QGVWKGSDDLGPEDTLKEVIKQGTLTIGFIGLAECLIALIGKHHGESKEAQELGLKIVSH
CCCCCCCCCCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
MRHKMDEATDKYKLNFSLMGTPAEGLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYY
HHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEE
NISAYDKIEIEAPYHELTNAGHITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPV
ECCCCCEEEEECCHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
DRDPICGFSGVITSNICPVCGRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRV
CCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
KHR
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8421692; 7610040; 9278503; 8083158; 7852304 [H]