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The map label for this gene is araD [H]

Identifier: 126697611

GI number: 126697611

Start: 69685

End: 70335

Strand: Direct

Name: araD [H]

Synonym: CD0045

Alternate gene names: 126697611

Gene position: 69685-70335 (Clockwise)

Preceding gene: 126697610

Following gene: 126697612

Centisome position: 1.62

GC content: 33.95

Gene sequence:

>651_bases
ATGTTATTAGAGAAATTAAGAAAAGAAGTATTACAAGCATCTTTAGACCTTTTAAACTATAATTTAGTGACATTAACAGG
AGGAAATGTAAGTGGGAGAGATGAACAAACTGGCTATATAGCAATCACCCCAAGTGGAATGGATTATAGAAATCTTACAC
CAAGTGATATTGTTATAGTAGATGTAGATGGAAATATTATAGATGGAAAATGGAAAGCATCAGTGGATTTATCAGACCAC
TTGTATATATATAAGCATAGAGAAGACATAAATAGTATAATTCATACACATTCTACATACTCAAGTTGTTTTGCTATTTT
AAATGAACCTATAGAATGCGCAAGTACAACTCTTGCAAATGAAGTAGGGGGTTCAGTACCAGTTGCAAAATTTTCGCCAC
CAACATCTAAAAAGATGGGAAAATGTGTTATTGAAGCAATTGGTGACAAAAGAGCATGTCTTTTAGCAAATCATGGCGTA
ATTGCAGTTGGTCCATCTGTAGGACATGCTCTTACAGCCGCTGTAATGTTAGAAGATTCAGCAAAAGTATATTACTTAGC
AAAATCAATTGGCACACCAGTGCTACTGCCTGATGAAGAAATTCAAAGAGCGAGAGATGTATTTTTTAATGTCTATGGTC
AGGATAAATAA

Upstream 100 bases:

>100_bases
TTTTAGAATTTTCAATCAAGACAATAACATAATAGCTAAGCAATTAGAACACAATTAAGATGTATAAGGCATGTATATGA
TGAATGGGAGGATTTAATTA

Downstream 100 bases:

>100_bases
ATTAGATAAAATTTTAAAAGTAATATGAAAATATAGATATTCAATGATATTAAGGAGATTTATAATGATATAATAAGTTT
AATAGTTAAGAAGTAAAATA

Product: sugar-phosphate aldolase

Products: NA

Alternate protein names: Phosphoribulose isomerase [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MLLEKLRKEVLQASLDLLNYNLVTLTGGNVSGRDEQTGYIAITPSGMDYRNLTPSDIVIVDVDGNIIDGKWKASVDLSDH
LYIYKHREDINSIIHTHSTYSSCFAILNEPIECASTTLANEVGGSVPVAKFSPPTSKKMGKCVIEAIGDKRACLLANHGV
IAVGPSVGHALTAAVMLEDSAKVYYLAKSIGTPVLLPDEEIQRARDVFFNVYGQDK

Sequences:

>Translated_216_residues
MLLEKLRKEVLQASLDLLNYNLVTLTGGNVSGRDEQTGYIAITPSGMDYRNLTPSDIVIVDVDGNIIDGKWKASVDLSDH
LYIYKHREDINSIIHTHSTYSSCFAILNEPIECASTTLANEVGGSVPVAKFSPPTSKKMGKCVIEAIGDKRACLLANHGV
IAVGPSVGHALTAAVMLEDSAKVYYLAKSIGTPVLLPDEEIQRARDVFFNVYGQDK
>Mature_216_residues
MLLEKLRKEVLQASLDLLNYNLVTLTGGNVSGRDEQTGYIAITPSGMDYRNLTPSDIVIVDVDGNIIDGKWKASVDLSDH
LYIYKHREDINSIIHTHSTYSSCFAILNEPIECASTTLANEVGGSVPVAKFSPPTSKKMGKCVIEAIGDKRACLLANHGV
IAVGPSVGHALTAAVMLEDSAKVYYLAKSIGTPVLLPDEEIQRARDVFFNVYGQDK

Specific function: Probable Pentulose-5-Phosphate-4-Epimerase. Probably Involved In A Metabolic Pathway With Sgah And Sgau. [C]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790642, Length=199, Percent_Identity=31.1557788944724, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786247, Length=211, Percent_Identity=31.2796208530806, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1789164, Length=210, Percent_Identity=32.8571428571429, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790008, Length=204, Percent_Identity=29.9019607843137, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1789094, Length=187, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR004661 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =5.1.3.4 [H]

Molecular weight: Translated: 23454; Mature: 23454

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLEKLRKEVLQASLDLLNYNLVTLTGGNVSGRDEQTGYIAITPSGMDYRNLTPSDIVIV
CHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEE
DVDGNIIDGKWKASVDLSDHLYIYKHREDINSIIHTHSTYSSCFAILNEPIECASTTLAN
ECCCCEECCEEEEEEECCCCEEEEEEHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHH
EVGGSVPVAKFSPPTSKKMGKCVIEAIGDKRACLLANHGVIAVGPSVGHALTAAVMLEDS
HCCCCCCEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCEEEECCCCCHHHEEEEEEECC
AKVYYLAKSIGTPVLLPDEEIQRARDVFFNVYGQDK
CEEEEEEHHCCCCEEECCHHHHHHHHHEEEEECCCC
>Mature Secondary Structure
MLLEKLRKEVLQASLDLLNYNLVTLTGGNVSGRDEQTGYIAITPSGMDYRNLTPSDIVIV
CHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEE
DVDGNIIDGKWKASVDLSDHLYIYKHREDINSIIHTHSTYSSCFAILNEPIECASTTLAN
ECCCCEECCEEEEEEECCCCEEEEEEHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHH
EVGGSVPVAKFSPPTSKKMGKCVIEAIGDKRACLLANHGVIAVGPSVGHALTAAVMLEDS
HCCCCCCEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCEEEECCCCCHHHEEEEEEECC
AKVYYLAKSIGTPVLLPDEEIQRARDVFFNVYGQDK
CEEEEEEHHCCCCEEECCHHHHHHHHHEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA