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The map label for this gene is fadR [H]

Identifier: 126447876

GI number: 126447876

Start: 1546049

End: 1546813

Strand: Direct

Name: fadR [H]

Synonym: BMA10247_A1609

Alternate gene names: 126447876

Gene position: 1546049-1546813 (Clockwise)

Preceding gene: 126446485

Following gene: 126447711

Centisome position: 65.71

GC content: 71.37

Gene sequence:

>765_bases
ATGACCGCCACTCAGAAAGCCGACCGCGCGGATGCGCCGCGCGCGCCCGCCGGGCGCAAGTCGCAGCAGCGCGTGCAGGA
CATCCTGCGCGCCGGGCGCGAAGTCTTCGCGGAAAAAGGCTACGAGCACGCCACCGCGGCGGAGATCGCGCAGCGCGTCG
GCGTGTCGGAGGCGACGGTGTTCAGCTACTTCCGCGGCAAACGGGAGCTGTGCGCGCGCGTGATCGCCGATTGGTACGAC
GAAATCGTCGACGCGTTCGAAACCGGCATGCCGCGCGACGGCTCGGTGCGGCAGCAGTTCGCGTTCGTCGTGCGCACGCA
CCTGCGGCTGATGCTCGTGAACGGCACCGGCCTCTGCGCGCTCGTGCTCTCCGAGGGGCGCGCGAAGCAGCACGCGCTCG
CCGATGAGCTGACGGCCTTGCAGCGCCGCTACACGGCGCCGCTGATGGACGTGCTCGCGCGCGGGCAGGCGACGGGACAG
GTGCGCGCCGACATGCCGCTCAGCCTGCTGCGCTCGATGGTGTTCGGGCCGATCGAGCACGTGCTGTGGGATGCGATCCT
CGGCCATCGCAAGCTCGACACCGAGACGACGGCCGAGCAGTTGATCGACCTGCTGTGGACGGGGCTGCAACCGCCCGCGC
CGGAAAACGCCGCGCTCGTGCGCTTCAGGAGCGACGTCGCGGACGCGATGCGGCGGCTCGACCAAGCATGCGGGCGCGCA
CCGCGCAAGGCGGCGGCGGGCCGCGACGCGCAAAAGCCCGCGTAG

Upstream 100 bases:

>100_bases
TCGCGCTTGATCCGCGCGAGCGTCAATAGTTTTTTGAGCAACACTCAGTTATGATCGACACCATCGCAACGAAACCGCCC
GACGCCGCGGGACAACCCGT

Downstream 100 bases:

>100_bases
CGGCCGCGCGCGCCGCCGCACGCCCCCGGCCGGCTCCATGCCGGCCCGCTATCGCGCCGCGAGCGCCTGCGGCCGCTTCG
CGATCATCTCGATCTCGAAC

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MTATQKADRADAPRAPAGRKSQQRVQDILRAGREVFAEKGYEHATAAEIAQRVGVSEATVFSYFRGKRELCARVIADWYD
EIVDAFETGMPRDGSVRQQFAFVVRTHLRLMLVNGTGLCALVLSEGRAKQHALADELTALQRRYTAPLMDVLARGQATGQ
VRADMPLSLLRSMVFGPIEHVLWDAILGHRKLDTETTAEQLIDLLWTGLQPPAPENAALVRFRSDVADAMRRLDQACGRA
PRKAAAGRDAQKPA

Sequences:

>Translated_254_residues
MTATQKADRADAPRAPAGRKSQQRVQDILRAGREVFAEKGYEHATAAEIAQRVGVSEATVFSYFRGKRELCARVIADWYD
EIVDAFETGMPRDGSVRQQFAFVVRTHLRLMLVNGTGLCALVLSEGRAKQHALADELTALQRRYTAPLMDVLARGQATGQ
VRADMPLSLLRSMVFGPIEHVLWDAILGHRKLDTETTAEQLIDLLWTGLQPPAPENAALVRFRSDVADAMRRLDQACGRA
PRKAAAGRDAQKPA
>Mature_253_residues
TATQKADRADAPRAPAGRKSQQRVQDILRAGREVFAEKGYEHATAAEIAQRVGVSEATVFSYFRGKRELCARVIADWYDE
IVDAFETGMPRDGSVRQQFAFVVRTHLRLMLVNGTGLCALVLSEGRAKQHALADELTALQRRYTAPLMDVLARGQATGQV
RADMPLSLLRSMVFGPIEHVLWDAILGHRKLDTETTAEQLIDLLWTGLQPPAPENAALVRFRSDVADAMRRLDQACGRAP
RKAAAGRDAQKPA

Specific function: Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation, including acdA, fadA, fadB, fadE, fadF, fadG, fadH, fadM, fadN, lcfA and lcfB. Binding of FadR to DNA is specifical

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647
- InterPro:   IPR013570 [H]

Pfam domain/function: PF08359 TetR_C_4; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 28032; Mature: 27901

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATQKADRADAPRAPAGRKSQQRVQDILRAGREVFAEKGYEHATAAEIAQRVGVSEATV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHH
FSYFRGKRELCARVIADWYDEIVDAFETGMPRDGSVRQQFAFVVRTHLRLMLVNGTGLCA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEECCCCHHH
LVLSEGRAKQHALADELTALQRRYTAPLMDVLARGQATGQVRADMPLSLLRSMVFGPIEH
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
VLWDAILGHRKLDTETTAEQLIDLLWTGLQPPAPENAALVRFRSDVADAMRRLDQACGRA
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
PRKAAAGRDAQKPA
CHHHHCCCCCCCCC
>Mature Secondary Structure 
TATQKADRADAPRAPAGRKSQQRVQDILRAGREVFAEKGYEHATAAEIAQRVGVSEATV
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHH
FSYFRGKRELCARVIADWYDEIVDAFETGMPRDGSVRQQFAFVVRTHLRLMLVNGTGLCA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEECCCCHHH
LVLSEGRAKQHALADELTALQRRYTAPLMDVLARGQATGQVRADMPLSLLRSMVFGPIEH
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
VLWDAILGHRKLDTETTAEQLIDLLWTGLQPPAPENAALVRFRSDVADAMRRLDQACGRA
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
PRKAAAGRDAQKPA
CHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]