Click here to switch to the map view.

The map label for this gene is cat2 [H]

Identifier: 126447579

GI number: 126447579

Start: 553708

End: 555045

Strand: Direct

Name: cat2 [H]

Synonym: BMA10247_A0610

Alternate gene names: 126447579

Gene position: 553708-555045 (Clockwise)

Preceding gene: 126447066

Following gene: 126447349

Centisome position: 23.54

GC content: 65.47

Gene sequence:

>1338_bases
TTGGGGATGCGAAACGATCGGGATGCGCGGGAGATCTACGCGGGAAAACTGACGTCGCCGCAGCGGGCGGTGTCGCAAGT
GCGCAGCGGTTCGGCGATCGCGCTCGGCATGGCGATGTCGCAGCCGCCCGCGCTGCTCGCCGCGCTCGCCGAGCGCGCGC
AGGCCGGCGACGTCGACGCGCTGCGTGTGTATTACTTTCATGCGGAGGCGTTTCTGCGCGAGACGCTGCTGCGCTATTCG
CTGATGGGGCGAATCCTGCCGCACTGCATGTTCATGGGGCCGCCCGAGCGCGAGCTCGTGAAGCTCGGCGAAGCGGACGG
CGGGCGCAAGGTCGTGTTCTTCGTGCCGAACTCGTTCAGCCAGTCGCCGCGGCTGTTCGCCGAACACGTCGACGTCGACA
CGATGCTCGTGATGGTCTCGCCGATGGATCGCAACGGCTACTTCACGTTCGGCACGAACAACGATTACACGAGCTCGGTC
GCGCGCGCCGCGCGCCGGCTGCTCGTCGAGGTGAACCCGAACATGCCGCGCGTGTTCGGCAACTCGCTGCTGCACGTGTC
CGAAGTGGACGCGATCGTCGAATCGGACCAACCGTTGCCGGAACTGATCCCGAAGCCCGGCGGCGAGCTCGATCGCGTGA
TCGGCGAACAGATCGCGGAACTCGTGACGGAGGGCGCGTGTCTGCAAATGGGGATCGGCGCGTTGCCCAATGCGGTATGC
GGCGCGCTCGTCGGCCATCGGCATCTCGGCATCCATACCGAGCTGCTGACGCCGGGGCTCGTCGAGCTGATTCGCCGCGG
GGCTGTCGACAACAGCCGCAAGACGCTCGATCGCGGCAAGTCGGTATTCACGTTCGCGATGGGCGATCGCGCGATGTACG
ATTTCATTCACGACAACCCGGCGCTCGAGAGCCATCCTGTCGACTACGTGAACGATCCGTGCAACATCGCGCGCAACGAC
AACATGATCTCCGTGAACTCGACGATCGAGATGGATCTGACGGGCGCATGCAATTCGGAGCATGTCAATGGGCACCAATA
CAGCGCGTCCGGCGGGCAGCTCGACTTCGTGCGCGGCGCGTATGCATCGCGCGGCGGCAAGTCGATCCTCGCGTTCCATT
CGACCGCGGCGGGCGCAACGGTGTCGAAGATCGTTCCGCAATTGACGGGCCCCGTCACGACGCCGCGCACCGATACGCAT
CTCGTCGTGACCGAATACGGTGTCGCGAACCTGAAGGGCCTGTCGTCGACCGAACGGGCGCGCGCGCTGATCCGGCTCGC
GCACCCCGATTTTCGCGACGCGCTGAGCGTACACGCACGCCGGCTGCACTTGATCTGA

Upstream 100 bases:

>100_bases
CGGTGTCATCGTGATGTCTTTCGAACGCACGATGCTGATCTATAAGCGCGGGCATTCGCCGGAAGCCGGCGCCAATTACT
GAGACCGAACGACGGGGAGG

Downstream 100 bases:

>100_bases
ATGGAGGATCGCATGGCGAGCACGATTGCCGACTACCTCGCGCGGACGCTGGCCGCCGCCGGCGTCACGAAGATCTGGGG
CGTGACGGGCGACAGCCTGA

Product: acetyl-CoA hydrolase/transferase family protein

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MGMRNDRDAREIYAGKLTSPQRAVSQVRSGSAIALGMAMSQPPALLAALAERAQAGDVDALRVYYFHAEAFLRETLLRYS
LMGRILPHCMFMGPPERELVKLGEADGGRKVVFFVPNSFSQSPRLFAEHVDVDTMLVMVSPMDRNGYFTFGTNNDYTSSV
ARAARRLLVEVNPNMPRVFGNSLLHVSEVDAIVESDQPLPELIPKPGGELDRVIGEQIAELVTEGACLQMGIGALPNAVC
GALVGHRHLGIHTELLTPGLVELIRRGAVDNSRKTLDRGKSVFTFAMGDRAMYDFIHDNPALESHPVDYVNDPCNIARND
NMISVNSTIEMDLTGACNSEHVNGHQYSASGGQLDFVRGAYASRGGKSILAFHSTAAGATVSKIVPQLTGPVTTPRTDTH
LVVTEYGVANLKGLSSTERARALIRLAHPDFRDALSVHARRLHLI

Sequences:

>Translated_445_residues
MGMRNDRDAREIYAGKLTSPQRAVSQVRSGSAIALGMAMSQPPALLAALAERAQAGDVDALRVYYFHAEAFLRETLLRYS
LMGRILPHCMFMGPPERELVKLGEADGGRKVVFFVPNSFSQSPRLFAEHVDVDTMLVMVSPMDRNGYFTFGTNNDYTSSV
ARAARRLLVEVNPNMPRVFGNSLLHVSEVDAIVESDQPLPELIPKPGGELDRVIGEQIAELVTEGACLQMGIGALPNAVC
GALVGHRHLGIHTELLTPGLVELIRRGAVDNSRKTLDRGKSVFTFAMGDRAMYDFIHDNPALESHPVDYVNDPCNIARND
NMISVNSTIEMDLTGACNSEHVNGHQYSASGGQLDFVRGAYASRGGKSILAFHSTAAGATVSKIVPQLTGPVTTPRTDTH
LVVTEYGVANLKGLSSTERARALIRLAHPDFRDALSVHARRLHLI
>Mature_444_residues
GMRNDRDAREIYAGKLTSPQRAVSQVRSGSAIALGMAMSQPPALLAALAERAQAGDVDALRVYYFHAEAFLRETLLRYSL
MGRILPHCMFMGPPERELVKLGEADGGRKVVFFVPNSFSQSPRLFAEHVDVDTMLVMVSPMDRNGYFTFGTNNDYTSSVA
RAARRLLVEVNPNMPRVFGNSLLHVSEVDAIVESDQPLPELIPKPGGELDRVIGEQIAELVTEGACLQMGIGALPNAVCG
ALVGHRHLGIHTELLTPGLVELIRRGAVDNSRKTLDRGKSVFTFAMGDRAMYDFIHDNPALESHPVDYVNDPCNIARNDN
MISVNSTIEMDLTGACNSEHVNGHQYSASGGQLDFVRGAYASRGGKSILAFHSTAAGATVSKIVPQLTGPVTTPRTDTHL
VVTEYGVANLKGLSSTERARALIRLAHPDFRDALSVHARRLHLI

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=270, Percent_Identity=28.8888888888889, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI32563853, Length=442, Percent_Identity=35.7466063348416, Blast_Score=249, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI17538151, Length=440, Percent_Identity=36.5909090909091, Blast_Score=247, Evalue=8e-66,
Organism=Saccharomyces cerevisiae, GI6319456, Length=280, Percent_Identity=31.7857142857143, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21358615, Length=429, Percent_Identity=37.0629370629371, Blast_Score=268, Evalue=8e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 48395; Mature: 48264

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMRNDRDAREIYAGKLTSPQRAVSQVRSGSAIALGMAMSQPPALLAALAERAQAGDVDA
CCCCCCCCHHHHHHCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCE
LRVYYFHAEAFLRETLLRYSLMGRILPHCMFMGPPERELVKLGEADGGRKVVFFVPNSFS
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCEEEEECCCCCC
QSPRLFAEHVDVDTMLVMVSPMDRNGYFTFGTNNDYTSSVARAARRLLVEVNPNMPRVFG
CCCHHHHHHCCCEEEEEEEECCCCCCEEEECCCCCHHHHHHHHHHHEEEEECCCCCHHHC
NSLLHVSEVDAIVESDQPLPELIPKPGGELDRVIGEQIAELVTEGACLQMGIGALPNAVC
CCEEEHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHH
GALVGHRHLGIHTELLTPGLVELIRRGAVDNSRKTLDRGKSVFTFAMGDRAMYDFIHDNP
HHHHCCCCCCEEHHHCCHHHHHHHHHCCCCCHHHHHHCCCCEEEEECCCHHHHHHHCCCC
ALESHPVDYVNDPCNIARNDNMISVNSTIEMDLTGACNSEHVNGHQYSASGGQLDFVRGA
CCCCCCCCCCCCCCCCCCCCCEEEECCEEEEEECCCCCCCCCCCCEECCCCCCEEHHHHH
YASRGGKSILAFHSTAAGATVSKIVPQLTGPVTTPRTDTHLVVTEYGVANLKGLSSTERA
HHCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHCCCCCHHHHH
RALIRLAHPDFRDALSVHARRLHLI
HHHHHHCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GMRNDRDAREIYAGKLTSPQRAVSQVRSGSAIALGMAMSQPPALLAALAERAQAGDVDA
CCCCCCCHHHHHHCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCE
LRVYYFHAEAFLRETLLRYSLMGRILPHCMFMGPPERELVKLGEADGGRKVVFFVPNSFS
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCEEEEECCCCCC
QSPRLFAEHVDVDTMLVMVSPMDRNGYFTFGTNNDYTSSVARAARRLLVEVNPNMPRVFG
CCCHHHHHHCCCEEEEEEEECCCCCCEEEECCCCCHHHHHHHHHHHEEEEECCCCCHHHC
NSLLHVSEVDAIVESDQPLPELIPKPGGELDRVIGEQIAELVTEGACLQMGIGALPNAVC
CCEEEHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHH
GALVGHRHLGIHTELLTPGLVELIRRGAVDNSRKTLDRGKSVFTFAMGDRAMYDFIHDNP
HHHHCCCCCCEEHHHCCHHHHHHHHHCCCCCHHHHHHCCCCEEEEECCCHHHHHHHCCCC
ALESHPVDYVNDPCNIARNDNMISVNSTIEMDLTGACNSEHVNGHQYSASGGQLDFVRGA
CCCCCCCCCCCCCCCCCCCCCEEEECCEEEEEECCCCCCCCCCCCEECCCCCCEEHHHHH
YASRGGKSILAFHSTAAGATVSKIVPQLTGPVTTPRTDTHLVVTEYGVANLKGLSSTERA
HHCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHCCCCCHHHHH
RALIRLAHPDFRDALSVHARRLHLI
HHHHHHCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]