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The map label for this gene is rstB [H]

Identifier: 126447466

GI number: 126447466

Start: 1471258

End: 1472586

Strand: Direct

Name: rstB [H]

Synonym: BMA10247_A1518

Alternate gene names: 126447466

Gene position: 1471258-1472586 (Clockwise)

Preceding gene: 126447802

Following gene: 126447766

Centisome position: 62.54

GC content: 70.35

Gene sequence:

>1329_bases
ATGCTGCGCTCGCTCGTCAGGCTGTATCTCGTCGTGGTCGTCTGCGCGTCGGCGGCGATCCTCTTCATCAATACGTCGTT
CACCCGCTTCTTCTACGAGCGGATATCGAGCGCCGCGCGCGAGACGCTCAGCACCTACGCGTTCGTGCTGAACGATTATC
TCGAACGCCATCCGGGCGCATCGCGGCAGCCCGCGCTGCGCGAGCTCGCGAAGCACGGCAACGAGGGCTTCGGCTTCATG
TCGATCGACGACGCGCGCAAGCTGCTGAGCGCCGAGCAGCAGCGCGATCTCGACCGCGGCGAGATCGCGATCAGCTACGA
CGGCAAGGACTATTTCATGCCGCTCGTCGACGGCACGGTGCTGCACGCGCGCCCGGACGAGCCGCCGAGCCTCGACATCC
AGATCTACGCATACCTGACCGTCGCGCTCGCGACGCTGCTCGCCGTCGCGCTGTGGATCCACTACCACTGGCGCGACCTG
CGCAAGCTCGAAGCGGCCGCGCGCGCGTTCGGCGACGGCCGGCTGTCGACGCGCGCCGAGCTCTCGCGCAAGTCGAACAT
CTACGAGCTGTCGCAGCAGTTCAACGACATGGCCGAACGCATCGAGGCGTCGATCCAGCAGCAGCGCGAGATGATGCACG
GCATCTCGCACGAGCTGAAGACGCCGCTCGCGCGGCTCGAGTTCGGCCTCGCGCTGCTGAGCTCGCCGGATGCGCCCGAG
CGCATGCGCGAGCGCCAGGCGGCGCTGCGCCGCGACGTGCGCGAGCTCGACGAACTCGTCACCGAGCTGCTGACGATCGG
CCGGCTCGAACAGGGCGAGCGGCACCTCGCGCTGATGCAGGTGATGGTCGCGGAACTGATCGACAGCGTCGCGGCGAGCG
TCGCGCACGAGATCGCCGATCGCCGGCTCACGCTCGACGTGTCGGCGCGCGGCGCGCCCGCATGCCACGTGTGCGACGCG
AAGCTCGTCGCGCGCGCGCTGCTGAACCTGATCCGCAACGGCATGCGTTACGCGTCGACGACGATCTCGCTGCGCGCGTC
GCTCGGCGAAGCGGGCGCGCTCGTGCTGAGCGTCGACGACGACGGCCCCGGCATCGCGGCGGCCGACCGCGACCGCGTGT
TCGAGCCGTTCCACCGGCTCGATTCGAGCCGCGACCGGCAAACGGGCGGCTTCGGCCTGGGCCTCACGATCGTGCGAAGC
GTCGCGCTCGCGCACGGCGGCGATGTGCGGCTCGACGACACGCCGCTCGGCGGCGCGCGCTTCGCGATCACGCTGCCCGC
GCTCGAGGCGCCGGGCCGCGAGCAGGACGCGCGCGGCGCCGCTGCTTGA

Upstream 100 bases:

>100_bases
GCTGCGGCGCCGCTTCGAGGATGCGTCGTCCGAGCCGCACAAGATCAAGACGATCTGGGGCCGCGGCTACCTGTTCAGCC
CATCCGCGTGGGACGACTGA

Downstream 100 bases:

>100_bases
CGCCACGCGTGCGGCAATCCGCGCGACGCGGCGGCGCTCGCGGTTTTTCGTGTTTTTCGCGGTTTCGGCCGTCAGACGAT
GCCGGCCGCGCGGGTGGATT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MLRSLVRLYLVVVVCASAAILFINTSFTRFFYERISSAARETLSTYAFVLNDYLERHPGASRQPALRELAKHGNEGFGFM
SIDDARKLLSAEQQRDLDRGEIAISYDGKDYFMPLVDGTVLHARPDEPPSLDIQIYAYLTVALATLLAVALWIHYHWRDL
RKLEAAARAFGDGRLSTRAELSRKSNIYELSQQFNDMAERIEASIQQQREMMHGISHELKTPLARLEFGLALLSSPDAPE
RMRERQAALRRDVRELDELVTELLTIGRLEQGERHLALMQVMVAELIDSVAASVAHEIADRRLTLDVSARGAPACHVCDA
KLVARALLNLIRNGMRYASTTISLRASLGEAGALVLSVDDDGPGIAAADRDRVFEPFHRLDSSRDRQTGGFGLGLTIVRS
VALAHGGDVRLDDTPLGGARFAITLPALEAPGREQDARGAAA

Sequences:

>Translated_442_residues
MLRSLVRLYLVVVVCASAAILFINTSFTRFFYERISSAARETLSTYAFVLNDYLERHPGASRQPALRELAKHGNEGFGFM
SIDDARKLLSAEQQRDLDRGEIAISYDGKDYFMPLVDGTVLHARPDEPPSLDIQIYAYLTVALATLLAVALWIHYHWRDL
RKLEAAARAFGDGRLSTRAELSRKSNIYELSQQFNDMAERIEASIQQQREMMHGISHELKTPLARLEFGLALLSSPDAPE
RMRERQAALRRDVRELDELVTELLTIGRLEQGERHLALMQVMVAELIDSVAASVAHEIADRRLTLDVSARGAPACHVCDA
KLVARALLNLIRNGMRYASTTISLRASLGEAGALVLSVDDDGPGIAAADRDRVFEPFHRLDSSRDRQTGGFGLGLTIVRS
VALAHGGDVRLDDTPLGGARFAITLPALEAPGREQDARGAAA
>Mature_442_residues
MLRSLVRLYLVVVVCASAAILFINTSFTRFFYERISSAARETLSTYAFVLNDYLERHPGASRQPALRELAKHGNEGFGFM
SIDDARKLLSAEQQRDLDRGEIAISYDGKDYFMPLVDGTVLHARPDEPPSLDIQIYAYLTVALATLLAVALWIHYHWRDL
RKLEAAARAFGDGRLSTRAELSRKSNIYELSQQFNDMAERIEASIQQQREMMHGISHELKTPLARLEFGLALLSSPDAPE
RMRERQAALRRDVRELDELVTELLTIGRLEQGERHLALMQVMVAELIDSVAASVAHEIADRRLTLDVSARGAPACHVCDA
KLVARALLNLIRNGMRYASTTISLRASLGEAGALVLSVDDDGPGIAAADRDRVFEPFHRLDSSRDRQTGGFGLGLTIVRS
VALAHGGDVRLDDTPLGGARFAITLPALEAPGREQDARGAAA

Specific function: Member of the two-component regulatory system rstB/rstA. RstB functions as a membrane-associated protein kinase that phosphorylates rstA (Potential) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787894, Length=296, Percent_Identity=40.5405405405405, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI1790346, Length=267, Percent_Identity=34.0823970037453, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1788393, Length=269, Percent_Identity=28.996282527881, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1786600, Length=222, Percent_Identity=30.1801801801802, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1789808, Length=291, Percent_Identity=27.4914089347079, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87082128, Length=299, Percent_Identity=28.4280936454849, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1786783, Length=303, Percent_Identity=28.3828382838284, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786912, Length=238, Percent_Identity=30.2521008403361, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI145693157, Length=239, Percent_Identity=22.5941422594142, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1789149, Length=230, Percent_Identity=25.2173913043478, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790551, Length=287, Percent_Identity=26.4808362369338, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790436, Length=216, Percent_Identity=28.7037037037037, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788713, Length=279, Percent_Identity=23.6559139784946, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788549, Length=219, Percent_Identity=23.7442922374429, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790861, Length=283, Percent_Identity=27.5618374558304, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI87081816, Length=248, Percent_Identity=24.1935483870968, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1787374, Length=337, Percent_Identity=24.9258160237389, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1790300, Length=277, Percent_Identity=27.4368231046931, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48828; Mature: 48828

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRSLVRLYLVVVVCASAAILFINTSFTRFFYERISSAARETLSTYAFVLNDYLERHPGA
CHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SRQPALRELAKHGNEGFGFMSIDDARKLLSAEQQRDLDRGEIAISYDGKDYFMPLVDGTV
CCCHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCCCEE
LHARPDEPPSLDIQIYAYLTVALATLLAVALWIHYHWRDLRKLEAAARAFGDGRLSTRAE
EECCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LSRKSNIYELSQQFNDMAERIEASIQQQREMMHGISHELKTPLARLEFGLALLSSPDAPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
RMRERQAALRRDVRELDELVTELLTIGRLEQGERHLALMQVMVAELIDSVAASVAHEIAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RRLTLDVSARGAPACHVCDAKLVARALLNLIRNGMRYASTTISLRASLGEAGALVLSVDD
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEECC
DGPGIAAADRDRVFEPFHRLDSSRDRQTGGFGLGLTIVRSVALAHGGDVRLDDTPLGGAR
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEECCCCCCCCE
FAITLPALEAPGREQDARGAAA
EEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLRSLVRLYLVVVVCASAAILFINTSFTRFFYERISSAARETLSTYAFVLNDYLERHPGA
CHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SRQPALRELAKHGNEGFGFMSIDDARKLLSAEQQRDLDRGEIAISYDGKDYFMPLVDGTV
CCCHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCCCEE
LHARPDEPPSLDIQIYAYLTVALATLLAVALWIHYHWRDLRKLEAAARAFGDGRLSTRAE
EECCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LSRKSNIYELSQQFNDMAERIEASIQQQREMMHGISHELKTPLARLEFGLALLSSPDAPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
RMRERQAALRRDVRELDELVTELLTIGRLEQGERHLALMQVMVAELIDSVAASVAHEIAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RRLTLDVSARGAPACHVCDAKLVARALLNLIRNGMRYASTTISLRASLGEAGALVLSVDD
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEECC
DGPGIAAADRDRVFEPFHRLDSSRDRQTGGFGLGLTIVRSVALAHGGDVRLDDTPLGGAR
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEECCCCCCCCE
FAITLPALEAPGREQDARGAAA
EEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 2646639; 1925016; 1495392 [H]