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The map label for this gene is aniA [H]

Identifier: 126447402

GI number: 126447402

Start: 1550068

End: 1551675

Strand: Direct

Name: aniA [H]

Synonym: BMA10247_A1613

Alternate gene names: 126447402

Gene position: 1550068-1551675 (Clockwise)

Preceding gene: 126447711

Following gene: 126445921

Centisome position: 65.88

GC content: 69.53

Gene sequence:

>1608_bases
ATGACGGCGCGAGCGCCGGCGCCGCCCGGGAAGACGCGGGCCGGGCACGAGCCGCATCCGCCGCCTGCCGCGCTTGGCTC
GCGTTCGCCGTGCCGGCGCGCCGCGGCGGCCGGCGCGGCGGAAACAAACACCGGGGGCCTCGACATGAACCCTGCCGTTG
ACCCGAGCCCGCTGTCGCGCGCGGCCCAGGCGCTTGCGCTGGCGTCGATCGGCGGCGCGCTGGCGCTCGGCGCGTGCACG
AGCCGCCCGTCGGGCGAGCGGTACGACCCGTCGCGCATGGACTTCAACCCAGGGCCCGCGATCGTCACGCAGACGCGCCA
CACGGGCCCGTTCGCCGCCGGCTCCGCGTTGAGCTTCGATGCCGCGCTCCAGCCGCTCGACGCAGCGCGGGACCAAGCGA
TCCGCCTCGATACCACGCACACGGTGATCCGGATCGCCCCGGGCATCGCGTTCGCCGCATGGACGTTCGGCAATCAGGTG
CCGGGGCCGACGGTGCATGTCAAGGTGGGCGATCGCGTGCGCTTGTCCATGACGAACCGCAGCGACGAGCCCGCCCCCGG
CGGCTTGCAACTGACCGCGCCGATGATGCATTCGATGGATTTCCATACGGCGATGGTCTCGCCCACGGACAAGTACCGGT
CGATCGCGCCGGGCCAGACGATGCATTTCGAGTTCACGCCGAACTACCCCGGCGTCTTCATGTACCGCTGCGGCACGCCG
AGGGTGCTCGAGCATATCGCGTCGGGCATGTATGGCGTCGTCGTCGTGGCGCCGCGCGACGGCTATCCGACCCGGGCCGA
TCGCGAATACGTGATCGTCCAGAGCGAGTTCTACACGAAGCCCGATCCGCAGCACCGCAGCGTGGGCACGGACGCGCTGC
ACGTGCTCGACGGCGAGCGCCTGCGCCGCAAAGCGCCGACCTACACGGTATTCAACGGCCGGTACAACGGCATGGTCACG
CAGCCGTTGATCGCGAAGCCCGGCGAGCGCGTGCGGCTCTACGTGCTCAACGCGGGGCCGAGCGACACCTCGAGCTTCCA
TGTCGTCGGCGCGATCTTCGACCGCGTCTGGCTCGACGGCAACCCCGACAATCAGTTGCGCGGCATGCAGACGGTGCTGC
TCGGCTCCAGCGGCAGCGCGATCGCGGCATTCGTCGTGCCGGAGGCCGGCGCCTACGTGATGGTCGATCATCAGTTCGCG
AACGCATCGCAAGGCGCGGTCGGCGTGATCGACGCCGGCGCGCATGAGGAATCGACCATCGAGCATCACAACATCCCCGC
GTCGGCCACGCCGACCGACGCGGAGGCGATACAGGGCAAGCTCGATTTCGAAAGCAAGTGTCTCGCCTGCCATACGCTCG
GACACGGCGCGAAGCTCGGCCCGGCTCTGCTCGGCGTGACGCAGCGGCGAAGCGACGCGTGGCTGCGGAGGTGGCTCGCC
TCGCCCGAGGCGATGGTCGCGAGCGACGCCGACGCGAGGGCGCTGCGCGCGCACTATCCGATCACCATGCCGGGCCAGAA
TCTGAGCGATAGCGAAATTCGCCGGTACGTCCGGTATTTCCATTGGGCGGACGAAGCATCGAAGCAACGGGACCACGCGA
TGCCCTGA

Upstream 100 bases:

>100_bases
CGGCGCTGCTGATGGCGTTCGACTTCGTGCTCAAGCTGGCGCCCCTGTTCCCTGCCGTCGTCAATCGAATGTCGCGGCAA
CACGGCGAAAAGCGCTCGCC

Downstream 100 bases:

>100_bases
TGACGAAGCGGCGGCGCGGACGGTTCCCGACGGCCCCAAGCGCCACGCGTCGAGCGCAATCGCGCGCGCCGGCCGGCGCG
CGCGGCGCGTCGATATCCGC

Product: multicopper oxidase domain-containing protein

Products: NA

Alternate protein names: Major outer membrane protein Pan 1 [H]

Number of amino acids: Translated: 535; Mature: 534

Protein sequence:

>535_residues
MTARAPAPPGKTRAGHEPHPPPAALGSRSPCRRAAAAGAAETNTGGLDMNPAVDPSPLSRAAQALALASIGGALALGACT
SRPSGERYDPSRMDFNPGPAIVTQTRHTGPFAAGSALSFDAALQPLDAARDQAIRLDTTHTVIRIAPGIAFAAWTFGNQV
PGPTVHVKVGDRVRLSMTNRSDEPAPGGLQLTAPMMHSMDFHTAMVSPTDKYRSIAPGQTMHFEFTPNYPGVFMYRCGTP
RVLEHIASGMYGVVVVAPRDGYPTRADREYVIVQSEFYTKPDPQHRSVGTDALHVLDGERLRRKAPTYTVFNGRYNGMVT
QPLIAKPGERVRLYVLNAGPSDTSSFHVVGAIFDRVWLDGNPDNQLRGMQTVLLGSSGSAIAAFVVPEAGAYVMVDHQFA
NASQGAVGVIDAGAHEESTIEHHNIPASATPTDAEAIQGKLDFESKCLACHTLGHGAKLGPALLGVTQRRSDAWLRRWLA
SPEAMVASDADARALRAHYPITMPGQNLSDSEIRRYVRYFHWADEASKQRDHAMP

Sequences:

>Translated_535_residues
MTARAPAPPGKTRAGHEPHPPPAALGSRSPCRRAAAAGAAETNTGGLDMNPAVDPSPLSRAAQALALASIGGALALGACT
SRPSGERYDPSRMDFNPGPAIVTQTRHTGPFAAGSALSFDAALQPLDAARDQAIRLDTTHTVIRIAPGIAFAAWTFGNQV
PGPTVHVKVGDRVRLSMTNRSDEPAPGGLQLTAPMMHSMDFHTAMVSPTDKYRSIAPGQTMHFEFTPNYPGVFMYRCGTP
RVLEHIASGMYGVVVVAPRDGYPTRADREYVIVQSEFYTKPDPQHRSVGTDALHVLDGERLRRKAPTYTVFNGRYNGMVT
QPLIAKPGERVRLYVLNAGPSDTSSFHVVGAIFDRVWLDGNPDNQLRGMQTVLLGSSGSAIAAFVVPEAGAYVMVDHQFA
NASQGAVGVIDAGAHEESTIEHHNIPASATPTDAEAIQGKLDFESKCLACHTLGHGAKLGPALLGVTQRRSDAWLRRWLA
SPEAMVASDADARALRAHYPITMPGQNLSDSEIRRYVRYFHWADEASKQRDHAMP
>Mature_534_residues
TARAPAPPGKTRAGHEPHPPPAALGSRSPCRRAAAAGAAETNTGGLDMNPAVDPSPLSRAAQALALASIGGALALGACTS
RPSGERYDPSRMDFNPGPAIVTQTRHTGPFAAGSALSFDAALQPLDAARDQAIRLDTTHTVIRIAPGIAFAAWTFGNQVP
GPTVHVKVGDRVRLSMTNRSDEPAPGGLQLTAPMMHSMDFHTAMVSPTDKYRSIAPGQTMHFEFTPNYPGVFMYRCGTPR
VLEHIASGMYGVVVVAPRDGYPTRADREYVIVQSEFYTKPDPQHRSVGTDALHVLDGERLRRKAPTYTVFNGRYNGMVTQ
PLIAKPGERVRLYVLNAGPSDTSSFHVVGAIFDRVWLDGNPDNQLRGMQTVLLGSSGSAIAAFVVPEAGAYVMVDHQFAN
ASQGAVGVIDAGAHEESTIEHHNIPASATPTDAEAIQGKLDFESKCLACHTLGHGAKLGPALLGVTQRRSDAWLRRWLAS
PEAMVASDADARALRAHYPITMPGQNLSDSEIRRYVRYFHWADEASKQRDHAMP

Specific function: Catalyzes the reduction of nitrite to nitric oxide (NO), probably with azurin as electron donor. Essential for growth and survival in oxygen-depleted environments. Can also provide protection against killing by normal human sera [H]

COG id: COG2132

COG function: function code Q; Putative multicopper oxidases

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 plastocyanin-like domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001117
- InterPro:   IPR011707
- InterPro:   IPR008972
- InterPro:   IPR001287 [H]

Pfam domain/function: PF00394 Cu-oxidase; PF07732 Cu-oxidase_3 [H]

EC number: =1.7.2.1 [H]

Molecular weight: Translated: 57354; Mature: 57223

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARAPAPPGKTRAGHEPHPPPAALGSRSPCRRAAAAGAAETNTGGLDMNPAVDPSPLSR
CCCCCCCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHH
AAQALALASIGGALALGACTSRPSGERYDPSRMDFNPGPAIVTQTRHTGPFAAGSALSFD
HHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEHH
AALQPLDAARDQAIRLDTTHTVIRIAPGIAFAAWTFGNQVPGPTVHVKVGDRVRLSMTNR
HHHCCHHHHCCCEEEEECCEEEEEECCCCEEEEEECCCCCCCCEEEEEECCEEEEEECCC
SDEPAPGGLQLTAPMMHSMDFHTAMVSPTDKYRSIAPGQTMHFEFTPNYPGVFMYRCGTP
CCCCCCCCEEEEHHHHHCCCCCEEECCCCHHHHCCCCCCEEEEEECCCCCCEEEEECCCH
RVLEHIASGMYGVVVVAPRDGYPTRADREYVIVQSEFYTKPDPQHRSVGTDALHVLDGER
HHHHHHHCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEECCCHH
LRRKAPTYTVFNGRYNGMVTQPLIAKPGERVRLYVLNAGPSDTSSFHVVGAIFDRVWLDG
HHHCCCCEEEECCEECCEECCCHHCCCCCEEEEEEEECCCCCCCCEEEHEEHHHHHCCCC
NPDNQLRGMQTVLLGSSGSAIAAFVVPEAGAYVMVDHQFANASQGAVGVIDAGAHEESTI
CCCCHHCCEEEEEECCCCCEEEEEEECCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCH
EHHNIPASATPTDAEAIQGKLDFESKCLACHTLGHGAKLGPALLGVTQRRSDAWLRRWLA
HHCCCCCCCCCCCHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHC
SPEAMVASDADARALRAHYPITMPGQNLSDSEIRRYVRYFHWADEASKQRDHAMP
CCCCEEECCCCHHHHEECCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TARAPAPPGKTRAGHEPHPPPAALGSRSPCRRAAAAGAAETNTGGLDMNPAVDPSPLSR
CCCCCCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHH
AAQALALASIGGALALGACTSRPSGERYDPSRMDFNPGPAIVTQTRHTGPFAAGSALSFD
HHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEHH
AALQPLDAARDQAIRLDTTHTVIRIAPGIAFAAWTFGNQVPGPTVHVKVGDRVRLSMTNR
HHHCCHHHHCCCEEEEECCEEEEEECCCCEEEEEECCCCCCCCEEEEEECCEEEEEECCC
SDEPAPGGLQLTAPMMHSMDFHTAMVSPTDKYRSIAPGQTMHFEFTPNYPGVFMYRCGTP
CCCCCCCCEEEEHHHHHCCCCCEEECCCCHHHHCCCCCCEEEEEECCCCCCEEEEECCCH
RVLEHIASGMYGVVVVAPRDGYPTRADREYVIVQSEFYTKPDPQHRSVGTDALHVLDGER
HHHHHHHCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEECCCHH
LRRKAPTYTVFNGRYNGMVTQPLIAKPGERVRLYVLNAGPSDTSSFHVVGAIFDRVWLDG
HHHCCCCEEEECCEECCEECCCHHCCCCCEEEEEEEECCCCCCCCEEEHEEHHHHHCCCC
NPDNQLRGMQTVLLGSSGSAIAAFVVPEAGAYVMVDHQFANASQGAVGVIDAGAHEESTI
CCCCHHCCEEEEEECCCCCEEEEEEECCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCH
EHHNIPASATPTDAEAIQGKLDFESKCLACHTLGHGAKLGPALLGVTQRRSDAWLRRWLA
HHCCCCCCCCCCCHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHC
SPEAMVASDADARALRAHYPITMPGQNLSDSEIRRYVRYFHWADEASKQRDHAMP
CCCCEEECCCCHHHHEECCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1383156; 1398981 [H]