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The map label for this gene is atpA-2

Identifier: 126447307

GI number: 126447307

Start: 126158

End: 128170

Strand: Direct

Name: atpA-2

Synonym: BMA10247_A0154

Alternate gene names: 126447307

Gene position: 126158-128170 (Clockwise)

Preceding gene: 126446645

Following gene: 126447933

Centisome position: 5.36

GC content: 73.77

Gene sequence:

>2013_bases
ATGACGCCGACGCCTGACGCACCCGCCGCCGCCGATGCCGCAACCGGCGCCGGCTGGCTCGCGCGCCGCCGGGGCGCACT
CGCGCGCGTCGCGCTCGCGCCCATCGCGCAGGCGATCGGGCGGGTCGAGCGCGTCGCGGACGGGATCGCGTTCGTGTCCG
GTCTCGAAGACACGATGCTCAACGAAGTGCTGCGTTTCGAAGGCGGCGTGACCGGCTTCGCGCATACGCTCGACGAGGAT
CTGATCAGCGTCGTGCTGCTCGATCCGGACGCGGGCGTTCGCGCGCAGACGGCGGTCGCGCGCACGGGCGCGGTGCTCGA
AGTGCCGGCCGGGCCGCAACTGCTCGGGCGCGTGGTCGATCCGCTCGGCCGCCCGCTCGACGGCGGCGCACCGCTCGATG
CGGCGCACACGCTGCCGATCGAGCGCGCCGCGCCGGCGATCATCGAGCGCGATCTCGTCAGCGAGCCGCTCGACACCGGC
GTGCTGATCGTCGACGCGCTCTTCACGATCGGGCGCGGCCAGCGCGAGCTGATCATCGGCGATCGCGCGACCGGCAAGAC
CTCGCTCGCGATCGACGCGATCGTCAACCAGCGGCATTCGGACGTGATCTGCGTGTACGTCGCGATCGGCCAGCGCGCGA
GCGCGGTGCGCCGCGTGATCGACGCGGTGCGCCGCTACGGCGCGCCCGAGCGCTGCGTCTTCGTCGTCGCGCCGGCCGCG
TGCGCGCCGGGGCTGCAGTGGATCGCGCCGTTCGCGGGCTTCTCGATCGCCGAATATTTCCGCGACCGCGGCCAACACGC
GCTCGTCGTCGTCGATGACCTGACAAAGCATGCGGCGACGCACCGCGAGCTCGCGCTGCTCACGCGCGAGCCGCCCGGCC
GCGAGGCGTATCCGGGCGACATCTTCTACGTGCACGCGCGCCTGCTCGAACGCGCGGCGAAGCTGTCGGCGGCGCTCGGC
GGCGGATCGCTGTCCGCGCTGCCGATCGCGGAGACCGATGCGGGCAACCTCGCCGCCTACATTCCGACGAACCTGATTTC
GATCACCGACGGGCAGATCGTGCTCGATTCGGCGCTGTTCGCCGCGAACCAGCGGCCGGCCGTCGACGTCGGGCTGAGCG
TGAGCCGCGTCGGCGGCAAGGCGCAGCATCCGGCGCTGCGCGCCGCGTCGGGCCGCCTGCGGCTCGACTATGCGCAGTTC
CTCGAGCTGGAGGCGTTCACGCGCTTCGGCGGGCTCACGGACGCGCGGCTGCGCGCGCAGATCACGCGCGGCGAGCGCAT
TCGCGCGTTGATCACGCAGCCGCGCTTTCGCGCGCTGCGCACGCTCGACGAAGTGGTGCTGCTCAAGGCGCTCGCGGCGG
GCACGCTCGATGCGATGTCGCCGGATCTCGTCGCGCCGCTGCGCGAGCGCTTGCCTGCGTGGCTCGATGCGCGGATCGCG
GCGCTCACGCCGGCGCTTGCGCCGCCGCGCGACTGGCTTGCGGACGATGCGGCGCTCGACGCGCTCGCGGAATCGGTCGG
CGAGCTGATCGAGCGGATCGCCGCGGACGCCGCGCGTCGCGCGACGGCGGGCATGCCGGCGGAGGACGCGGCGGGCGACA
TCGGCGGCGCGTTCGGCGGCGAGCAGGCGCGCGGCGATGCGGATCGTGATGCGGATCATGGCGCGAATCGCGAGGTCAGT
CGCGAGGTCAGTCCCGAGGCGAGTCGCGAAGTGAGCCGTGAAGTGAGCCGTGAAGTGAGCCACGAGGCCGATCGAGACGC
GGCCGCCGATGCGGCGCGCGTCGCCGGTCGGGCGCCCGGGCGCGCCGAGCCGGATCGCGCGGTCCCACGCGCGATGCCCG
ACGGGCCGCCGCGCGCGCAGGCCGACGGCGATCGCGCATCGGCGTCTCGGCCGCCGCCCGATGCGCGCGGCGACGCGGCG
CGCACCGCACCGTCTCCGCAAGGCGGCGCCGACGCCAACGTCAATGCCGATGCCAACGTCGATGCCGAAGCCGAAGCGAG
GCACAAGCGATGA

Upstream 100 bases:

>100_bases
GCGCTGATCGCCGGGCTCGAGCTCGAATCGAAATACGCGAACGTGCGCAACAGCCTGCGCCAGGATCTCGCGACCATCGA
GGCAGCGTTGCTGAACGAAG

Downstream 100 bases:

>100_bases
GTGACAAGCTCGCCGCGATCGAGGCGCGCACCGATACCGCTCGTCAACTGCAGACCGTGATCGGTGCGATGCAGGGCGTG
GCCGCCGCGCGCGCGCACGA

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha 2; F-ATPase subunit alpha 2

Number of amino acids: Translated: 670; Mature: 669

Protein sequence:

>670_residues
MTPTPDAPAAADAATGAGWLARRRGALARVALAPIAQAIGRVERVADGIAFVSGLEDTMLNEVLRFEGGVTGFAHTLDED
LISVVLLDPDAGVRAQTAVARTGAVLEVPAGPQLLGRVVDPLGRPLDGGAPLDAAHTLPIERAAPAIIERDLVSEPLDTG
VLIVDALFTIGRGQRELIIGDRATGKTSLAIDAIVNQRHSDVICVYVAIGQRASAVRRVIDAVRRYGAPERCVFVVAPAA
CAPGLQWIAPFAGFSIAEYFRDRGQHALVVVDDLTKHAATHRELALLTREPPGREAYPGDIFYVHARLLERAAKLSAALG
GGSLSALPIAETDAGNLAAYIPTNLISITDGQIVLDSALFAANQRPAVDVGLSVSRVGGKAQHPALRAASGRLRLDYAQF
LELEAFTRFGGLTDARLRAQITRGERIRALITQPRFRALRTLDEVVLLKALAAGTLDAMSPDLVAPLRERLPAWLDARIA
ALTPALAPPRDWLADDAALDALAESVGELIERIAADAARRATAGMPAEDAAGDIGGAFGGEQARGDADRDADHGANREVS
REVSPEASREVSREVSREVSHEADRDAAADAARVAGRAPGRAEPDRAVPRAMPDGPPRAQADGDRASASRPPPDARGDAA
RTAPSPQGGADANVNADANVDAEAEARHKR

Sequences:

>Translated_670_residues
MTPTPDAPAAADAATGAGWLARRRGALARVALAPIAQAIGRVERVADGIAFVSGLEDTMLNEVLRFEGGVTGFAHTLDED
LISVVLLDPDAGVRAQTAVARTGAVLEVPAGPQLLGRVVDPLGRPLDGGAPLDAAHTLPIERAAPAIIERDLVSEPLDTG
VLIVDALFTIGRGQRELIIGDRATGKTSLAIDAIVNQRHSDVICVYVAIGQRASAVRRVIDAVRRYGAPERCVFVVAPAA
CAPGLQWIAPFAGFSIAEYFRDRGQHALVVVDDLTKHAATHRELALLTREPPGREAYPGDIFYVHARLLERAAKLSAALG
GGSLSALPIAETDAGNLAAYIPTNLISITDGQIVLDSALFAANQRPAVDVGLSVSRVGGKAQHPALRAASGRLRLDYAQF
LELEAFTRFGGLTDARLRAQITRGERIRALITQPRFRALRTLDEVVLLKALAAGTLDAMSPDLVAPLRERLPAWLDARIA
ALTPALAPPRDWLADDAALDALAESVGELIERIAADAARRATAGMPAEDAAGDIGGAFGGEQARGDADRDADHGANREVS
REVSPEASREVSREVSREVSHEADRDAAADAARVAGRAPGRAEPDRAVPRAMPDGPPRAQADGDRASASRPPPDARGDAA
RTAPSPQGGADANVNADANVDAEAEARHKR
>Mature_669_residues
TPTPDAPAAADAATGAGWLARRRGALARVALAPIAQAIGRVERVADGIAFVSGLEDTMLNEVLRFEGGVTGFAHTLDEDL
ISVVLLDPDAGVRAQTAVARTGAVLEVPAGPQLLGRVVDPLGRPLDGGAPLDAAHTLPIERAAPAIIERDLVSEPLDTGV
LIVDALFTIGRGQRELIIGDRATGKTSLAIDAIVNQRHSDVICVYVAIGQRASAVRRVIDAVRRYGAPERCVFVVAPAAC
APGLQWIAPFAGFSIAEYFRDRGQHALVVVDDLTKHAATHRELALLTREPPGREAYPGDIFYVHARLLERAAKLSAALGG
GSLSALPIAETDAGNLAAYIPTNLISITDGQIVLDSALFAANQRPAVDVGLSVSRVGGKAQHPALRAASGRLRLDYAQFL
ELEAFTRFGGLTDARLRAQITRGERIRALITQPRFRALRTLDEVVLLKALAAGTLDAMSPDLVAPLRERLPAWLDARIAA
LTPALAPPRDWLADDAALDALAESVGELIERIAADAARRATAGMPAEDAAGDIGGAFGGEQARGDADRDADHGANREVSR
EVSPEASREVSREVSREVSHEADRDAAADAARVAGRAPGRAEPDRAVPRAMPDGPPRAQADGDRASASRPPPDARGDAAR
TAPSPQGGADANVNADANVDAEAEARHKR

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=451, Percent_Identity=45.2328159645233, Blast_Score=402, Evalue=1e-112,
Organism=Homo sapiens, GI4757810, Length=451, Percent_Identity=45.2328159645233, Blast_Score=402, Evalue=1e-112,
Organism=Homo sapiens, GI32189394, Length=375, Percent_Identity=24.2666666666667, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI19913426, Length=310, Percent_Identity=25.8064516129032, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI19913428, Length=311, Percent_Identity=26.0450160771704, Blast_Score=86, Evalue=8e-17,
Organism=Escherichia coli, GI1790172, Length=461, Percent_Identity=44.0347071583514, Blast_Score=386, Evalue=1e-108,
Organism=Escherichia coli, GI1788251, Length=270, Percent_Identity=35.9259259259259, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1790170, Length=340, Percent_Identity=24.1176470588235, Blast_Score=85, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71988063, Length=478, Percent_Identity=44.7698744769874, Blast_Score=414, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI71988080, Length=478, Percent_Identity=44.7698744769874, Blast_Score=414, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI71988074, Length=478, Percent_Identity=41.2133891213389, Blast_Score=368, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17510931, Length=348, Percent_Identity=26.1494252873563, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17570191, Length=309, Percent_Identity=26.537216828479, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI25144756, Length=375, Percent_Identity=23.7333333333333, Blast_Score=91, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319370, Length=446, Percent_Identity=47.9820627802691, Blast_Score=408, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6319603, Length=295, Percent_Identity=26.7796610169492, Blast_Score=94, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6322581, Length=409, Percent_Identity=23.7163814180929, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24658560, Length=456, Percent_Identity=45.6140350877193, Blast_Score=409, Evalue=1e-114,
Organism=Drosophila melanogaster, GI281361666, Length=315, Percent_Identity=26.3492063492064, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24646341, Length=315, Percent_Identity=26.3492063492064, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI17136796, Length=315, Percent_Identity=26.3492063492064, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24638766, Length=375, Percent_Identity=23.7333333333333, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28574560, Length=374, Percent_Identity=23.7967914438503, Blast_Score=80, Evalue=7e-15,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA2_BURM7 (A3MAS4)

Other databases:

- EMBL:   CP000547
- RefSeq:   YP_001077360.1
- ProteinModelPortal:   A3MAS4
- SMR:   A3MAS4
- GeneID:   4890040
- GenomeReviews:   CP000547_GR
- KEGG:   bmn:BMA10247_A0154
- TIGR:   BMA10247_A0154
- HOGENOM:   HBG565875
- OMA:   NVLCVYC
- ProtClustDB:   PRK13343
- BioCyc:   BMAL320389:BMA10247_A0154-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 70297; Mature: 70166

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPTPDAPAAADAATGAGWLARRRGALARVALAPIAQAIGRVERVADGIAFVSGLEDTML
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NEVLRFEGGVTGFAHTLDEDLISVVLLDPDAGVRAQTAVARTGAVLEVPAGPQLLGRVVD
HHHHHHCCCCCHHHHHHHHHCEEEEEECCCCCCCHHHHHHHCCCEEECCCCHHHHHHHHH
PLGRPLDGGAPLDAAHTLPIERAAPAIIERDLVSEPLDTGVLIVDALFTIGRGQRELIIG
HHCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEE
DRATGKTSLAIDAIVNQRHSDVICVYVAIGQRASAVRRVIDAVRRYGAPERCVFVVAPAA
CCCCCCHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEECHH
CAPGLQWIAPFAGFSIAEYFRDRGQHALVVVDDLTKHAATHRELALLTREPPGREAYPGD
HCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHEEECCCCCCCCCCCC
IFYVHARLLERAAKLSAALGGGSLSALPIAETDAGNLAAYIPTNLISITDGQIVLDSALF
HHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCEEEECCCCEEEECCCCEEEHHHHH
AANQRPAVDVGLSVSRVGGKAQHPALRAASGRLRLDYAQFLELEAFTRFGGLTDARLRAQ
HCCCCCCEEECCCHHHCCCCCCCCHHHHCCCCEEECHHHHHHHHHHHHHCCCCCHHHHHH
ITRGERIRALITQPRFRALRTLDEVVLLKALAAGTLDAMSPDLVAPLRERLPAWLDARIA
HHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHCCHHHHHHHH
ALTPALAPPRDWLADDAALDALAESVGELIERIAADAARRATAGMPAEDAAGDIGGAFGG
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCC
EQARGDADRDADHGANREVSREVSPEASREVSREVSREVSHEADRDAAADAARVAGRAPG
CCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCC
RAEPDRAVPRAMPDGPPRAQADGDRASASRPPPDARGDAARTAPSPQGGADANVNADANV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DAEAEARHKR
CCHHHHCCCC
>Mature Secondary Structure 
TPTPDAPAAADAATGAGWLARRRGALARVALAPIAQAIGRVERVADGIAFVSGLEDTML
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NEVLRFEGGVTGFAHTLDEDLISVVLLDPDAGVRAQTAVARTGAVLEVPAGPQLLGRVVD
HHHHHHCCCCCHHHHHHHHHCEEEEEECCCCCCCHHHHHHHCCCEEECCCCHHHHHHHHH
PLGRPLDGGAPLDAAHTLPIERAAPAIIERDLVSEPLDTGVLIVDALFTIGRGQRELIIG
HHCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEE
DRATGKTSLAIDAIVNQRHSDVICVYVAIGQRASAVRRVIDAVRRYGAPERCVFVVAPAA
CCCCCCHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEECHH
CAPGLQWIAPFAGFSIAEYFRDRGQHALVVVDDLTKHAATHRELALLTREPPGREAYPGD
HCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHEEECCCCCCCCCCCC
IFYVHARLLERAAKLSAALGGGSLSALPIAETDAGNLAAYIPTNLISITDGQIVLDSALF
HHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCEEEECCCCEEEECCCCEEEHHHHH
AANQRPAVDVGLSVSRVGGKAQHPALRAASGRLRLDYAQFLELEAFTRFGGLTDARLRAQ
HCCCCCCEEECCCHHHCCCCCCCCHHHHCCCCEEECHHHHHHHHHHHHHCCCCCHHHHHH
ITRGERIRALITQPRFRALRTLDEVVLLKALAAGTLDAMSPDLVAPLRERLPAWLDARIA
HHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHCCHHHHHHHH
ALTPALAPPRDWLADDAALDALAESVGELIERIAADAARRATAGMPAEDAAGDIGGAFGG
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCC
EQARGDADRDADHGANREVSREVSPEASREVSREVSREVSHEADRDAAADAARVAGRAPG
CCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCC
RAEPDRAVPRAMPDGPPRAQADGDRASASRPPPDARGDAARTAPSPQGGADANVNADANV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DAEAEARHKR
CCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA