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The map label for this gene is ptxR [H]

Identifier: 126447296

GI number: 126447296

Start: 103548

End: 104453

Strand: Reverse

Name: ptxR [H]

Synonym: BMA10247_A0122

Alternate gene names: 126447296

Gene position: 104453-103548 (Counterclockwise)

Preceding gene: 126445978

Following gene: 126447405

Centisome position: 4.44

GC content: 72.85

Gene sequence:

>906_bases
ATGGCGGACATCCGTGACGTCAATCTGAACCGGCTGGCGATCTTCGTCGCCGTGGTCGAGGCGGGATCGCTGACGGCGGC
GGCCGAACGGCTCGGCCTCGCGAAGACGATGGTGAGCGCGCATGTGCAGCGGCTCGAGGCGGAAGTCGGCGCGAGCCTCG
TCGTGCGAACCACGCGGCGGCTCAACGTGACGGAGGCAGGCCGCGCGTTCTACGATGCGTGCCGCGACATCCTGCGCGCG
ACCGAAACGGCGCTCGCCGCGGTGGCGGGGGACGCGGGCCCGCTGCGCGGCACGTTGCGCGTGAGCGCGCCCGTCGATTA
CGGCGCGCTCGTCGTCGCGCCGGCGCTCGTCGCGCTGCGCGACGCGCATCCGGCGCTCGAGATCGAATTGCAGTGCGACG
ACCGCGTCGTCGATCTCGTGCGCGACAACCTAGACGTCGCGATCCGGCTCGGCAGGCTCGCCGATTCGAACCATCGCGCG
GCGAAGCTCGGCGGCTTCGAGCGCTGGCTCGTCGCAAGCCCGGCGTTCGTCGCGCGCCACGGCGCGCCGGCCTCGCCCGA
AGCGCTCGGCGCGCTGCCGTACGTGATGCTGTCGACGGTGCCGCGCACGACGCTCGAGCTCGCGAACGCGCACGGCGAGC
GCGCGAGCGTGCGTTGCAGGCGCGCGTTCGCGTCGAACACGGCAACCGCTTGCCGCGCGGCGGTGCTCGCGGGCGGCGGC
TTCGGCGTCGCGACGAGCTTCTCGAGCGCCGACGACATCGCGGCCGGCCGGCTCGTGCGCCTGCTGCCCGGCTGGTCGTT
TCCGCCCGGCGACATCCATGCGGTGTTTCCATCGGCGAGCCATCCGTCCGCGAAGGTGCGCGCGCTGATCGACATGCTGA
AGACGCGGCTGGCCGCGCCATGCTGA

Upstream 100 bases:

>100_bases
GTTTAAAGGGACTTTGCTAGAAGCCCATTGGCCCTATCGAAGGGGGCAGGTCAGATGGATAATTGCCGAAATACAATCCT
CAATGAATGGACAATCGGCC

Downstream 100 bases:

>100_bases
AGGGGCGAGCGCCGCGTCACGTCGAAGCTGCGTCACGTCCAAGCCGCGGCGCGCGAGCCGCGCAAGCGCGAGCGGCGCGC
GATTGCGGCTCGAAGCAGCA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MADIRDVNLNRLAIFVAVVEAGSLTAAAERLGLAKTMVSAHVQRLEAEVGASLVVRTTRRLNVTEAGRAFYDACRDILRA
TETALAAVAGDAGPLRGTLRVSAPVDYGALVVAPALVALRDAHPALEIELQCDDRVVDLVRDNLDVAIRLGRLADSNHRA
AKLGGFERWLVASPAFVARHGAPASPEALGALPYVMLSTVPRTTLELANAHGERASVRCRRAFASNTATACRAAVLAGGG
FGVATSFSSADDIAAGRLVRLLPGWSFPPGDIHAVFPSASHPSAKVRALIDMLKTRLAAPC

Sequences:

>Translated_301_residues
MADIRDVNLNRLAIFVAVVEAGSLTAAAERLGLAKTMVSAHVQRLEAEVGASLVVRTTRRLNVTEAGRAFYDACRDILRA
TETALAAVAGDAGPLRGTLRVSAPVDYGALVVAPALVALRDAHPALEIELQCDDRVVDLVRDNLDVAIRLGRLADSNHRA
AKLGGFERWLVASPAFVARHGAPASPEALGALPYVMLSTVPRTTLELANAHGERASVRCRRAFASNTATACRAAVLAGGG
FGVATSFSSADDIAAGRLVRLLPGWSFPPGDIHAVFPSASHPSAKVRALIDMLKTRLAAPC
>Mature_300_residues
ADIRDVNLNRLAIFVAVVEAGSLTAAAERLGLAKTMVSAHVQRLEAEVGASLVVRTTRRLNVTEAGRAFYDACRDILRAT
ETALAAVAGDAGPLRGTLRVSAPVDYGALVVAPALVALRDAHPALEIELQCDDRVVDLVRDNLDVAIRLGRLADSNHRAA
KLGGFERWLVASPAFVARHGAPASPEALGALPYVMLSTVPRTTLELANAHGERASVRCRRAFASNTATACRAAVLAGGGF
GVATSFSSADDIAAGRLVRLLPGWSFPPGDIHAVFPSASHPSAKVRALIDMLKTRLAAPC

Specific function: Transcriptional activator of the toxA (exotoxin) and regA genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081978, Length=292, Percent_Identity=33.9041095890411, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1786401, Length=291, Percent_Identity=31.9587628865979, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789639, Length=285, Percent_Identity=28.4210526315789, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI145693193, Length=292, Percent_Identity=29.7945205479452, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1789440, Length=295, Percent_Identity=26.7796610169492, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1787128, Length=290, Percent_Identity=25.8620689655172, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787589, Length=289, Percent_Identity=26.2975778546713, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1788297, Length=146, Percent_Identity=35.6164383561644, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789173, Length=252, Percent_Identity=26.984126984127, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788481, Length=237, Percent_Identity=26.5822784810127, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787879, Length=150, Percent_Identity=30.6666666666667, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31579; Mature: 31447

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADIRDVNLNRLAIFVAVVEAGSLTAAAERLGLAKTMVSAHVQRLEAEVGASLVVRTTRR
CCCCCCCCHHHHEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHH
LNVTEAGRAFYDACRDILRATETALAAVAGDAGPLRGTLRVSAPVDYGALVVAPALVALR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHH
DAHPALEIELQCDDRVVDLVRDNLDVAIRLGRLADSNHRAAKLGGFERWLVASPAFVARH
CCCCCEEEEEECCHHHHHHHHCCCCEEEEECCCCCCCCCHHHHCCCHHHHHCCCHHHHHC
GAPASPEALGALPYVMLSTVPRTTLELANAHGERASVRCRRAFASNTATACRAAVLAGGG
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCC
FGVATSFSSADDIAAGRLVRLLPGWSFPPGDIHAVFPSASHPSAKVRALIDMLKTRLAAP
CCEECCCCCCCHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCC
C
C
>Mature Secondary Structure 
ADIRDVNLNRLAIFVAVVEAGSLTAAAERLGLAKTMVSAHVQRLEAEVGASLVVRTTRR
CCCCCCCHHHHEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHH
LNVTEAGRAFYDACRDILRATETALAAVAGDAGPLRGTLRVSAPVDYGALVVAPALVALR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHH
DAHPALEIELQCDDRVVDLVRDNLDVAIRLGRLADSNHRAAKLGGFERWLVASPAFVARH
CCCCCEEEEEECCHHHHHHHHCCCCEEEEECCCCCCCCCHHHHCCCHHHHHCCCHHHHHC
GAPASPEALGALPYVMLSTVPRTTLELANAHGERASVRCRRAFASNTATACRAAVLAGGG
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCC
FGVATSFSSADDIAAGRLVRLLPGWSFPPGDIHAVFPSASHPSAKVRALIDMLKTRLAAP
CCEECCCCCCCHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCC
C
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8843437; 10984043 [H]