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The map label for this gene is cdd [H]

Identifier: 126447250

GI number: 126447250

Start: 113334

End: 113726

Strand: Direct

Name: cdd [H]

Synonym: BMA10247_A0139

Alternate gene names: 126447250

Gene position: 113334-113726 (Clockwise)

Preceding gene: 126445902

Following gene: 126447910

Centisome position: 4.82

GC content: 67.43

Gene sequence:

>393_bases
ATGACGCATCACGCATTGATCGAAGCGGCGAAGGCCGCGCGCGAAAAGGCCTACGCGCCGTATTCGAACTTCAAGGTCGG
CGCGGCGCTCGTGACGAACGACGGCAAGGTCTTCCACGGCTGCAACGTCGAGAACGCGTCGTACGGGCTGTGCAATTGCG
CGGAGCGCACCGCCTTGTTTTCTGCGCTCGCGGCGGGCTACCGGCCGGGCGAGTTCGCGGCGATCGCGGTCGTCGGCGAG
ACGCACGGGCCGATCGCGCCGTGCGGCGCGTGCCGGCAGGTCATGATCGAGCTCGGCAAGCCGACGCTCGAAGTCGTGTT
GACGAACATGCAGGGCGACGTGCGCGTGACGAGCGCGGGTGACCTGCTGCCGGACGCGTTCTATCTGGCGTGA

Upstream 100 bases:

>100_bases
GAATCCCGAGGCGACATGCATCGCCGGCGTTCGCCGCCCGGAAACGAATCACTGGACATCGAATCACCCAACATCGAATC
ACCGAACGAGGTCACACGAC

Downstream 100 bases:

>100_bases
CGCGGCGCGGCGCCGTCGGGGCGCGCGCGGTGCGCTCCGACGCGTATTCCGCCCGCTTCGGCTGCTTCGGCTGCTTCGCC
CGCTGCGGCTGCTTCGCCCA

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 130; Mature: 129

Protein sequence:

>130_residues
MTHHALIEAAKAAREKAYAPYSNFKVGAALVTNDGKVFHGCNVENASYGLCNCAERTALFSALAAGYRPGEFAAIAVVGE
THGPIAPCGACRQVMIELGKPTLEVVLTNMQGDVRVTSAGDLLPDAFYLA

Sequences:

>Translated_130_residues
MTHHALIEAAKAAREKAYAPYSNFKVGAALVTNDGKVFHGCNVENASYGLCNCAERTALFSALAAGYRPGEFAAIAVVGE
THGPIAPCGACRQVMIELGKPTLEVVLTNMQGDVRVTSAGDLLPDAFYLA
>Mature_129_residues
THHALIEAAKAAREKAYAPYSNFKVGAALVTNDGKVFHGCNVENASYGLCNCAERTALFSALAAGYRPGEFAAIAVVGET
HGPIAPCGACRQVMIELGKPTLEVVLTNMQGDVRVTSAGDLLPDAFYLA

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=125, Percent_Identity=45.6, Blast_Score=110, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17540514, Length=122, Percent_Identity=50, Blast_Score=112, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17551074, Length=123, Percent_Identity=48.780487804878, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6323274, Length=126, Percent_Identity=42.0634920634921, Blast_Score=100, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24582741, Length=132, Percent_Identity=46.969696969697, Blast_Score=105, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24582744, Length=137, Percent_Identity=38.6861313868613, Blast_Score=86, Evalue=7e-18,
Organism=Drosophila melanogaster, GI19920920, Length=141, Percent_Identity=39.7163120567376, Blast_Score=86, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 13630; Mature: 13499

Theoretical pI: Translated: 6.49; Mature: 6.49

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHHALIEAAKAAREKAYAPYSNFKVGAALVTNDGKVFHGCNVENASYGLCNCAERTALF
CCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCEEECCCCCCCCCCCHHHHHHHHHH
SALAAGYRPGEFAAIAVVGETHGPIAPCGACRQVMIELGKPTLEVVLTNMQGDVRVTSAG
HHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCC
DLLPDAFYLA
CCCCCCCCCC
>Mature Secondary Structure 
THHALIEAAKAAREKAYAPYSNFKVGAALVTNDGKVFHGCNVENASYGLCNCAERTALF
CHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCEEECCCCCCCCCCCHHHHHHHHHH
SALAAGYRPGEFAAIAVVGETHGPIAPCGACRQVMIELGKPTLEVVLTNMQGDVRVTSAG
HHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCC
DLLPDAFYLA
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2526291; 8969508; 9384377 [H]