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The map label for this gene is pcaR [H]

Identifier: 126447230

GI number: 126447230

Start: 735054

End: 735839

Strand: Reverse

Name: pcaR [H]

Synonym: BMA10247_A0797

Alternate gene names: 126447230

Gene position: 735839-735054 (Counterclockwise)

Preceding gene: 126447396

Following gene: 126445838

Centisome position: 31.28

GC content: 67.18

Gene sequence:

>786_bases
ATGAGCACAGAATTTCAGGCCAAACCCGGCGACTCCTATGTCCAGTCGTTCGCGCGCGGACTCGCGGTGATTCGCGCGTT
CGACGCGGAGCACCCCGAGCAGACGCTCACCGAGGTCGCCTCCGCGACCGGCCTGACCCGCGCGGGCGCGCGGCGCATCC
TGCTGACGCTGCAGACGCTCGGCTACGTCGAGGCCGACGGCCGCCTGTTCCGGCTCACGCCGAAGATCCTCGATCTCGGC
TTCGCGTATCTGACATCGATGCCGTTCTGGAACCTCGCCGAGCCGGTGATGGAGCAATTGTCCGCGCGCATCCACGAAAG
CTGCTCGGCGGCCGTGCTCGATCGCACCGAAATCGTGTACGTGCTGCGCGTGCCGACGCACAAGATCATGACGATCAATC
TGTCGATCGGCAGCCGGCTGCCCGCGTACTGCACGTCGATGGGCCGCGTGCTGCTGTCGTCGCTCGACGCCGCCGCGCTC
GACGACACGCTCGCGCGAAGCACGCTGCGCGCGTACACGCCGCGCACGCTCACCGATCCCGCCGCGCTGAAGGACGAGAT
CGCGACCGTGCGCAGCCAGGGCTGGGCGATCGTCGATCAGGAACTGGAAGCCGGATTGATTTCATTGTCGGCGCCGATCC
GCAACCGGCGCGGGCAGGTGATCGCCGCGATGAACATCAGCGGCAACGCGCAGCGGCACACCGCGAAGCAAATGGTGAAG
GCATTCCTCGATCCGCTGCTGGAAGCGTCGCAAACCGTGTCGCAGCTCGTCGCGCGGCGCGGCTGA

Upstream 100 bases:

>100_bases
GCGCGGCTGCCCGTCAAGCGCCGGGCCCATGCGGGGCGCGGGTTGGCGCAACCCGACCCCATGCGCTAATCTTCTCCGCT
GCACATCATTTCCACCCGCC

Downstream 100 bases:

>100_bases
GCCACGGCTGAAACGGTTCCGCGGCACCGCCCGAACACCGCTGACGCGCCGCTTGCACAGGCGCGCTTGGGAGCCGCCCC
GCCCCCAAGCGCGCACTCTT

Product: beta-ketoadipate pathway transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MSTEFQAKPGDSYVQSFARGLAVIRAFDAEHPEQTLTEVASATGLTRAGARRILLTLQTLGYVEADGRLFRLTPKILDLG
FAYLTSMPFWNLAEPVMEQLSARIHESCSAAVLDRTEIVYVLRVPTHKIMTINLSIGSRLPAYCTSMGRVLLSSLDAAAL
DDTLARSTLRAYTPRTLTDPAALKDEIATVRSQGWAIVDQELEAGLISLSAPIRNRRGQVIAAMNISGNAQRHTAKQMVK
AFLDPLLEASQTVSQLVARRG

Sequences:

>Translated_261_residues
MSTEFQAKPGDSYVQSFARGLAVIRAFDAEHPEQTLTEVASATGLTRAGARRILLTLQTLGYVEADGRLFRLTPKILDLG
FAYLTSMPFWNLAEPVMEQLSARIHESCSAAVLDRTEIVYVLRVPTHKIMTINLSIGSRLPAYCTSMGRVLLSSLDAAAL
DDTLARSTLRAYTPRTLTDPAALKDEIATVRSQGWAIVDQELEAGLISLSAPIRNRRGQVIAAMNISGNAQRHTAKQMVK
AFLDPLLEASQTVSQLVARRG
>Mature_260_residues
STEFQAKPGDSYVQSFARGLAVIRAFDAEHPEQTLTEVASATGLTRAGARRILLTLQTLGYVEADGRLFRLTPKILDLGF
AYLTSMPFWNLAEPVMEQLSARIHESCSAAVLDRTEIVYVLRVPTHKIMTINLSIGSRLPAYCTSMGRVLLSSLDAAALD
DTLARSTLRAYTPRTLTDPAALKDEIATVRSQGWAIVDQELEAGLISLSAPIRNRRGQVIAAMNISGNAQRHTAKQMVKA
FLDPLLEASQTVSQLVARRG

Specific function: Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI87082359, Length=250, Percent_Identity=29.2, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1786468, Length=218, Percent_Identity=30.7339449541284, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1788131, Length=222, Percent_Identity=31.0810810810811, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1789999, Length=249, Percent_Identity=29.3172690763052, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786715, Length=237, Percent_Identity=24.8945147679325, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788581, Length=159, Percent_Identity=27.0440251572327, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790752, Length=193, Percent_Identity=24.3523316062176, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28499; Mature: 28368

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTEFQAKPGDSYVQSFARGLAVIRAFDAEHPEQTLTEVASATGLTRAGARRILLTLQTL
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
GYVEADGRLFRLTPKILDLGFAYLTSMPFWNLAEPVMEQLSARIHESCSAAVLDRTEIVY
CEEECCCEEEEECHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
VLRVPTHKIMTINLSIGSRLPAYCTSMGRVLLSSLDAAALDDTLARSTLRAYTPRTLTDP
EEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
AALKDEIATVRSQGWAIVDQELEAGLISLSAPIRNRRGQVIAAMNISGNAQRHTAKQMVK
HHHHHHHHHHHHCCCEEEHHHHHCCHHEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHH
AFLDPLLEASQTVSQLVARRG
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STEFQAKPGDSYVQSFARGLAVIRAFDAEHPEQTLTEVASATGLTRAGARRILLTLQTL
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
GYVEADGRLFRLTPKILDLGFAYLTSMPFWNLAEPVMEQLSARIHESCSAAVLDRTEIVY
CEEECCCEEEEECHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
VLRVPTHKIMTINLSIGSRLPAYCTSMGRVLLSSLDAAALDDTLARSTLRAYTPRTLTDP
EEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
AALKDEIATVRSQGWAIVDQELEAGLISLSAPIRNRRGQVIAAMNISGNAQRHTAKQMVK
HHHHHHHHHHHHCCCEEEHHHHHCCHHEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHH
AFLDPLLEASQTVSQLVARRG
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083169 [H]