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The map label for this gene is fabL [H]

Identifier: 126447162

GI number: 126447162

Start: 2314109

End: 2320972

Strand: Reverse

Name: fabL [H]

Synonym: BMA10247_A2380

Alternate gene names: 126447162

Gene position: 2320972-2314109 (Counterclockwise)

Preceding gene: 262192845

Following gene: 126445850

Centisome position: 98.65

GC content: 71.34

Gene sequence:

>6864_bases
ATGTCGAATTCCTATTTGTTGGGGAAGCGTGTGCTGGTGACGGGCGGGGCAAAGAATGTCGGCAAGGCGATTTGCCGCCG
CTTTGCCGAAGAAGGCGCGCACGTCATCATCAATTTCTTTCATTCGCTCGACGCGTCGAAGCAGACCGCGGCCGAGTTGC
GCGCGCTCGGCGCGACGGTCGACGTCGTGCGCGCGTCGGTTGCGCAGCCGGCTCAGGTCGAGCGAATGTTCGACGAAATC
GAAGCGAAGTACGGCAAGATCGACATTCTCGTGAACAACGCGGCCTCGGGCGCGTTGCTGCCGGTGGACGACATCGAGGC
CGCGCACTTCGACCGCGCGCTCGACACGAACCTGAAGGGCGCGTTCTGGTGCGCGCGCCGCGCGGCGCGGCTGATGGCGC
GCGCGGGCGGCGGCGCGATCGTCAACGTGTCGTCGGTGGGCGCGACGCTCGTGCCGGCGAACTATCTCGTCGTCGGCACC
GCGAAAGCCGCGCTCGAATCGCTCACGCGCTATTTGGCCGTCGAATACGCGAGCCTCGGCATTCGCGTGAACGGCGCGTC
GTCGACGCTGATCGACGGTGACGTGGCCGCGCAGTTTCCCGATCCCGAGAACACCAAGCGTTCGAGCATCGCGGCGACGC
CGCTCGGCCGCCTCGCGACCCCCGAGGATCTCGCGGACGTCGTGCTGTTTCTCGCATCCGACGCGGCGCGCTGGATCACG
GGGCAGGTGATCGTCGCGGACGGCGGGCTCTCGCTGTGCAGCGAGGCGCTTTCGCCGCGGCGCGAATGGCGCGGCGCGCG
GCAGACGGCAGGCGGCGACGGCGCGTTGCTGCCGGATACGCCGGATACGCTGGCGGGGCTCGCGGCGTTTCCGAGCCGGG
CGAGCGCGGGCGCGGCTTCGGCCGCGCCATTGGCCGCCTCGCGCGATGCGGGCCCGGATGCGTTCGCGGCGGGGGCCGGT
AGCGGCGCCGGCGCGGGCGTGGCGGTGATGGGCACGGTGACGCAGGCGGCGAGCGGGCACTTGCGCGCCGCGTCGGGCGC
TGCCGGCGCGGCGCGCGCGCCGGCAGCGGTAGTCCACGCGGCGCGCGCGGTTGCTTCTCAGGCGGCGGAGGATGCGGCAC
CGGCTCGTGTTCCGGCGGTGACGACGACGGCGGAAATCGCGTCCGCATCGCGCTCGTCCGGTACGGCGCCGGCGTCGGCT
GCGCGTGTGCCCGCCGATGCCGGCGCAGCCGCGTCGCACGGCGCGCCTGCGCCGATGCCTTCCGACGCGGTTGCAACGCG
TCTCGCCGCAATCGGCGCGCCGGCGTCGACGTCCGACGCCGACACCGACGCCGACACCGACGCCGACACCGACACCGACA
CCGACGAAATCGCCGTCGTCGGCATGGGCGTCGCGCTGCCCGGCGCGAGCGACCCGCAGGCGTTCTGGCGCGCACTGCTG
AACGGCCCCGAGCTGTTCGGCAACGTGCCGCCCGATCGTTGGGATTACCGATCGTTCTATTCGCCCGATCCGTCGGCGGA
AGACAAGAGCTACCAATCGCGTTCGGTGTTCATCGAGCATTTCGAGCCCGAGACGCGGCTGCGCGCCGAAATCGAGGCGG
GCGCCGCGCCGCACGAGCTGACGACGCTGTGGTTGCGCCATTCGCTGCGCCAGGCGCTCGACGGCGTGCGCGTGCGCGCG
GGCGATCGCACGTCGTTCCTCGTCGGCTACACGGCGGACGGCAGTCAGCATCTGGAAGAAGGCATGGTGCTCGCGGCGAT
GCGCGCGCGGCTGCGCGAGACGCTCGACGAAGCGGGCGTGCCGCCCGACGAGCGCGAACGCCGTATCGCGCAGATCGACG
CGGTGCTGCGCGCGCGCTATGCGCGCGGCACGGGCGAGCTGGCCGAATATTTCCCGCATCGCGTCGGCTTGAACGCGATG
CGCGGCGTGCTGCCCGACGACGCCGAATACATGATGGTCGACACCGCGTGCTCGTCGTCGCTCTATTCGGTCGACCTCGG
CATCAAGAGCCTGCTCGCCGGCCAGCACGATGTCGTCGCGTGCGGCGGCGCGTTCGCGCTCGCGCCGCGCGGCTCGATCC
TGTTCTCGAAGCTGCACGGGCTCTCGAAGAGCGGCGAAGTGCGCCCGCTCGACAAGGCGTGCGACGGCGTGCTATTCGCC
GACGGCGCGGGCGTCGTGATCCTGAAGCGCCTGAAGCGCGCGCTCGCCGACGGCGACCGCGTGCTCGGCGTGCTGAAGGC
GTTCGGTTCGTCGTCGGACGGCAAGGGCAAGGCGATCTACGCGCCGAACTCGGCGGGCCAGAGCATCGCGATCGAGCGCG
CGTACCGGCAGACCGACGTGCGCAAGGAAGCGGTCGACTGGGTGGTCGCGCACGCGACCGGCACCCCGGCGGGCGACCTC
GCCGAGTTCCAGAGCCTGCGCGAGAAACTCAAGGGCGATCGCCCGGTGTACGTGACGTCGAACAAGTCGCTCGTCGGCCA
TACCGGTTGGGCGGCGGGCGTCGTCTCGCTGATCCAGGTGCTGCTCGCGCTCGAGCACGGGCGCATTCCGCCGCAGCATC
GCTTCTCCGAGCCGCCGCGCGAATTCGGCATCGAATCGAGCGGCTTCACGATTCCGACTCAGGCGGTGGACTGGCCGCGC
AAGGCCGATGCGGCGCGCGTCGCCGCGGTGTCGGGCTTCGGCTTCGGCGGCACGAACGGCCATCTGATCGTCGGCGAATA
TCGGCCTGACCTGAGCGCGTCGAAGCCCGCCGCGCGCGTGAGCCGCGAGCCGCTCGCGATCGTCGGCTGGTCCGCGAAAT
TTCCGGCGCTCGACGGCCGCGATGCCATCGCCGCATGGCTGAACGGCGCGGGCCCGGCGCCCGGTGCGAGCTTCGGCCGC
GCGTATCCGCTGCCGAGCTTCGATCGCGTGCGCATGCCGCCCGCGGTGCTGCGCGCGCTCGATCGCTGCCAGCTGATGGT
ACTCGACGCCGCGCACGACATGCGCGAGCAACTGCGCGATTACTGGAGCGCGCATGCGAATGCGATCGGCGTCGTGATGG
GCCACATGGGACCGACGCGCAACGCCGCGCTGTATGCGAGCCGCTGCTACATCGACGACATCGCGACCGCCGTGCGCGCG
CGCTTCGACGACGCGGCGCGCGCGCCGCTCGACGACGCGCTCGCGCGCGCCGCCGACAGGACGAGAAGCCTGGTGCCGCC
GACGACCGAGAATGCGTTCCCCGGCATGATGCCGAACGTGATTCCGGCGCGCGTGGCGAACTATCACGATCTGCACGGGA
TGAACATGACCGTCGACGCCGGGCATGCGTCGACGCTTGCCGCGTTCGAAGTCGCGTCGCGCTTCCTGAGAAGCGGCGAG
CTCGACATGGTGATCGTCGGCGGCGTCAACGGCAATTCGGCCGACGAAGTGCAGCCCGCGTTCGACCAGCCGCTCGCCGA
AGGGATCGTGCTGTTCGCGGTGACGACGAAGGCGCAGGCCGAGGCAGCCGGGCTGCCGGCGCTCGCTTGGATCGAGAGCG
ATCGGGCGTTCGCGGACGCCGCCTCGGCGCCGCCGGCCGCGTTGCGCGATGCGCAAGGCCGCGAGCTCACGTACGCGGGC
GCCGACGGCGCGCTGGCGGTGCTGCGCGCGCTCGTCGGCGGCGCGGACGCGGTGTCGGTCGCGCTTGGCAATGCGCGCGA
CCAGGTGCGCTTCGGCTTGCGCATCGATCGCCATGCGCCGCCGGCGAGCGGCGATGGCGGTGTACGCTCGCGTCGCGTGT
TCGGCGATTCGTCTTCGTCTTCGGCGACGACTGCGGCGACGACTGCGACGACTGCAACGACGACTGCAACGACGACTGCA
ACGACGACTGCAACGACGACTGCAACGACGACTGCAACGGCTCCCGTTTCTTCTCACCTTTACGCATCGTCGTCGGTCCT
CGCCGCGCCGTCGGCCACGTCGCCGACGCCTGTCGCGCCGTGCTCGACGGCCGTGCAGGCGGCCCGGCCGGCCCCCGCCG
CGACGATCGCGGCAGAGGCGACAGAGGCGCCCCATGCCGCTGCCGCCCGCGCCGCCTCCGTTGCCGACAAGCGCGTGCCG
ATCCCCGCCACGCTGAAAGCGACCGACGTTGCCGCCGACGGCGAGCCGCTCGGCGTCGCCCGCTATCGGATCGACCTCCA
GGAAACGCCGTGGCACGCGGGCGCGGGCGCGATCGCGTATCTGCCCGCGGGCAGCGTCGTCGTCACCGACGCCCCCGAGT
TGCTCGACGGCATCGGCATGCTGCCCGCCGACCTGCTCGTGCTGTCGACGCGCGCCGCCGCGTTCTCGCGCGCGCGGCTC
GTCGTCGTCGATACGCTCGGCGAAACCGCGTTGCAAGGGCTGATTCCGGCGGGCACGCGTCACGTGCGGCTGCTCACGTC
GCTGCATGCGGGCGCGCTCGCGCCGCAGCGCCTGTCGGCGCCGTCGCCCGAGCGGCTGAAGCTGCACGATCTCGCGTTCC
TCGCGCTCAAGCAGTGCTACGACAGCGTCGCGCAGCAGGGCTCGTTCATCGCGCTGCTGCTCGACGCGGTGAAGGACGAC
GTGCTGCACCCCGATGCGGGCATGTTCACGGGCCTCGTGAAGGCGCTCGCGATCGAGCTGCCGCACGCGCGCTCGCTCGC
GGTGCTGACGGACGACGCGGACATCCGGCACGGCGTCGCGCGGGCCGAGCGCGAGAGCGGCGCACAGCATCTGCTGCCCG
TCGTCGCGCTGTGCGGCACGCGCCGCCTGACGCCGCGCGTGACGCGCGACGCGGGCGAGCTGCCTGCCGACGGCCTCGCG
CGGCTCGGGCCCGATTCGGTCGTCGTCGCGTTCGGCGGCGCGCGCGGGATCACCGCCGAGCTGATGAAGGCGCTCGCCGA
ACACTTCCGGCCGACGATCTACCTGATCGGCAGCAGCGCGCTCGACGTGCACGGCCCGGAGGTGTTCGCCGGCAGCGACG
AAGCGTTCGCGCGCCGTCGCCCCGACTACATCCGCGAGCAGAAGGCGCTCGATCCGAACCTGCCGCTGCCCGCGATCATC
AAGGCGTTCGAGCGCCAGGTCGAGGCGCGCGCCGCACGCCGCAACATCGACGTGATGAAGTCGTACTGCGGGCCGAACAA
GGTGTTCTATCTGCGCGCCGACGTGCTCGACGCGGCCAGCGTGCGCGCGGCGGTCGAGCGGATCGCCACGGCCGGCCAGC
CGATCGATCTCGTCGTCAACGCGGCGGGCCTGAACCGCTCCGCGTCGGTCAACGTGAAATCGTTCGACGATTTCGTCGCG
GTGCGCGACATCAAGGTGCGCGGCTACTGGAACGTGCGCGCCGCGTTCGGCGCCGAGCAGCCGCGCGCATGGTGCAACTT
CGGCTCGTTCATCGGCCTCACGGGGCAGGCGGGCGAGACCGATTACGCGTCGGGCAACGATTTCCTCAACACGCAGGCCG
CATACCATCGCGCGGCGCTCGCGCGCGACGAGTTCACGATCGGCTGGACGCTGTGGCGCTCGGTGGGGCTCGGCGCGAAT
CCCGTCACGCGCGCGTTCCTCGAGAAGAGCGGGCTCTTCACGAGCATGCGGACCAACGAGGGCATTCATCACTTCCTGCG
CGAGATCAACCTGGCCGAGCGCGCGGCGAGCTCCGTGCATCTGGGCGCGGCCGAGCGGCGCGCGATCGAGGCGCATCTGC
CGACGTTCTTCGATGCGCCCGACGCCGCGCAGGCGCCGGCCATGCAAGCGCCGCAAGCCGCGCAAGCACAAGCACGGGCG
TGGCAAGCGGCGCAGGCGTCGGCCACGCCGCAGCCCCCGCACTCGCCGCACTCCCCGCAGATCGCCCCGAACGCGCGCAT
CGGACAGGCCCCAACGCCCGCGCGCGCGCGCATCGCATCGCCGCCGAGCCACGATTTCTATCTTGGCCGCGAAGTGCGAC
GCACGAGCGACAGCGTGATGTTCGAGCGCGTCTTCGATCTGCGCACCGATGCGTATTTGCAGCACCACGTCGTGAACCGC
TTCGCGACGCTGCCCGGCACGTTCGTGCCCGAGCTCGCGGCCGAGGCGGCGATGAAGCTGCTGCCGGGGCTGCGCGTGGT
CGGCTTTCGCGACGCCGCGTTCCGCCATTTCCTGCGCGTGTACGATGCGCAGCGGCCGAGCACGAAGCGCATCCACGCGC
AGGTCGTCGGCCGCGAGGGCGAGGCGGCCGTCGTGCAGGTGCGCATCACGGGCGACGTGCTCGCGCCGAACGGGCAGGTG
CTCGTCCAGGACAAGCTGCACTTCGAGATCAAGGCGCTCGTCGCGCCGCGCCACCCGAGCGCGCCCGTCTGGCCGATGCG
CCCCGACGAGCCGCGCACGCCGGTTGCCGATCCGTACCACTTCGAATCGGCGCCCGTGCGGCTGACGGGCATGTTCGTGT
CGACCGCGGATACGGGCGTCACCGCGACGGGCAAGGCCGCGCGCTACCAGTTGAACGTCGCCGCCGACGATCCGGTGTTC
TCGCGTTTCGTGATCCCGAGCATCATGCTCGACGGCCTCGCGCGCGTCGCGGTGCTGAACTATGTCGCGAACGACTACAT
TCCGCTCGCCGCGCCGGTGTCGATCGGGCGGATCGATCTGTACGAGGGGGGCAACGACTGCGAGCTCGCGCGCCGCTACG
ACCGGATCGACCTGTACGCGACGCCGCGCGCGTTCGCGCTCGAAGGCGCGCACGGCGGCAACCGCTTCGCGGCGGTGCGC
CCCGACGGCCGGATGCTGATGGAGATGGGCGACGTGTCGGGCGTCGTGATCGGCTACGTGCACCGTACGACGGGCGCATA
CGCGACGAAGGCCGAGGTCGACGCGCTCGCCGCGCGCCTCGCAACCGAGCGGGAGACGGCATGA

Upstream 100 bases:

>100_bases
GCCGCACACGCATCGCGCGCCACGAGAATAACGAGAGGAGAGGGCCGGATCAGACGGAGAGTCTCGTCCGAATGTTTGGT
AATCCTGACCACTGCGATTT

Downstream 100 bases:

>100_bases
GCAAGCACCGCCAGGCGCCGGGGCCGCGCGGCGGCCTCGTGATGGGCAACCTCGCCGCATACAAGCGCAATCCGATCACG
ATGCTGCTGCGGCTGCATCA

Product: putative polyketide synthase

Products: NA

Alternate protein names: Enoyl-acyl carrier protein reductase III; NADPH-dependent enoyl-ACP reductase [H]

Number of amino acids: Translated: 2287; Mature: 2286

Protein sequence:

>2287_residues
MSNSYLLGKRVLVTGGAKNVGKAICRRFAEEGAHVIINFFHSLDASKQTAAELRALGATVDVVRASVAQPAQVERMFDEI
EAKYGKIDILVNNAASGALLPVDDIEAAHFDRALDTNLKGAFWCARRAARLMARAGGGAIVNVSSVGATLVPANYLVVGT
AKAALESLTRYLAVEYASLGIRVNGASSTLIDGDVAAQFPDPENTKRSSIAATPLGRLATPEDLADVVLFLASDAARWIT
GQVIVADGGLSLCSEALSPRREWRGARQTAGGDGALLPDTPDTLAGLAAFPSRASAGAASAAPLAASRDAGPDAFAAGAG
SGAGAGVAVMGTVTQAASGHLRAASGAAGAARAPAAVVHAARAVASQAAEDAAPARVPAVTTTAEIASASRSSGTAPASA
ARVPADAGAAASHGAPAPMPSDAVATRLAAIGAPASTSDADTDADTDADTDTDTDEIAVVGMGVALPGASDPQAFWRALL
NGPELFGNVPPDRWDYRSFYSPDPSAEDKSYQSRSVFIEHFEPETRLRAEIEAGAAPHELTTLWLRHSLRQALDGVRVRA
GDRTSFLVGYTADGSQHLEEGMVLAAMRARLRETLDEAGVPPDERERRIAQIDAVLRARYARGTGELAEYFPHRVGLNAM
RGVLPDDAEYMMVDTACSSSLYSVDLGIKSLLAGQHDVVACGGAFALAPRGSILFSKLHGLSKSGEVRPLDKACDGVLFA
DGAGVVILKRLKRALADGDRVLGVLKAFGSSSDGKGKAIYAPNSAGQSIAIERAYRQTDVRKEAVDWVVAHATGTPAGDL
AEFQSLREKLKGDRPVYVTSNKSLVGHTGWAAGVVSLIQVLLALEHGRIPPQHRFSEPPREFGIESSGFTIPTQAVDWPR
KADAARVAAVSGFGFGGTNGHLIVGEYRPDLSASKPAARVSREPLAIVGWSAKFPALDGRDAIAAWLNGAGPAPGASFGR
AYPLPSFDRVRMPPAVLRALDRCQLMVLDAAHDMREQLRDYWSAHANAIGVVMGHMGPTRNAALYASRCYIDDIATAVRA
RFDDAARAPLDDALARAADRTRSLVPPTTENAFPGMMPNVIPARVANYHDLHGMNMTVDAGHASTLAAFEVASRFLRSGE
LDMVIVGGVNGNSADEVQPAFDQPLAEGIVLFAVTTKAQAEAAGLPALAWIESDRAFADAASAPPAALRDAQGRELTYAG
ADGALAVLRALVGGADAVSVALGNARDQVRFGLRIDRHAPPASGDGGVRSRRVFGDSSSSSATTAATTATTATTTATTTA
TTTATTTATTTATAPVSSHLYASSSVLAAPSATSPTPVAPCSTAVQAARPAPAATIAAEATEAPHAAAARAASVADKRVP
IPATLKATDVAADGEPLGVARYRIDLQETPWHAGAGAIAYLPAGSVVVTDAPELLDGIGMLPADLLVLSTRAAAFSRARL
VVVDTLGETALQGLIPAGTRHVRLLTSLHAGALAPQRLSAPSPERLKLHDLAFLALKQCYDSVAQQGSFIALLLDAVKDD
VLHPDAGMFTGLVKALAIELPHARSLAVLTDDADIRHGVARAERESGAQHLLPVVALCGTRRLTPRVTRDAGELPADGLA
RLGPDSVVVAFGGARGITAELMKALAEHFRPTIYLIGSSALDVHGPEVFAGSDEAFARRRPDYIREQKALDPNLPLPAII
KAFERQVEARAARRNIDVMKSYCGPNKVFYLRADVLDAASVRAAVERIATAGQPIDLVVNAAGLNRSASVNVKSFDDFVA
VRDIKVRGYWNVRAAFGAEQPRAWCNFGSFIGLTGQAGETDYASGNDFLNTQAAYHRAALARDEFTIGWTLWRSVGLGAN
PVTRAFLEKSGLFTSMRTNEGIHHFLREINLAERAASSVHLGAAERRAIEAHLPTFFDAPDAAQAPAMQAPQAAQAQARA
WQAAQASATPQPPHSPHSPQIAPNARIGQAPTPARARIASPPSHDFYLGREVRRTSDSVMFERVFDLRTDAYLQHHVVNR
FATLPGTFVPELAAEAAMKLLPGLRVVGFRDAAFRHFLRVYDAQRPSTKRIHAQVVGREGEAAVVQVRITGDVLAPNGQV
LVQDKLHFEIKALVAPRHPSAPVWPMRPDEPRTPVADPYHFESAPVRLTGMFVSTADTGVTATGKAARYQLNVAADDPVF
SRFVIPSIMLDGLARVAVLNYVANDYIPLAAPVSIGRIDLYEGGNDCELARRYDRIDLYATPRAFALEGAHGGNRFAAVR
PDGRMLMEMGDVSGVVIGYVHRTTGAYATKAEVDALAARLATERETA

Sequences:

>Translated_2287_residues
MSNSYLLGKRVLVTGGAKNVGKAICRRFAEEGAHVIINFFHSLDASKQTAAELRALGATVDVVRASVAQPAQVERMFDEI
EAKYGKIDILVNNAASGALLPVDDIEAAHFDRALDTNLKGAFWCARRAARLMARAGGGAIVNVSSVGATLVPANYLVVGT
AKAALESLTRYLAVEYASLGIRVNGASSTLIDGDVAAQFPDPENTKRSSIAATPLGRLATPEDLADVVLFLASDAARWIT
GQVIVADGGLSLCSEALSPRREWRGARQTAGGDGALLPDTPDTLAGLAAFPSRASAGAASAAPLAASRDAGPDAFAAGAG
SGAGAGVAVMGTVTQAASGHLRAASGAAGAARAPAAVVHAARAVASQAAEDAAPARVPAVTTTAEIASASRSSGTAPASA
ARVPADAGAAASHGAPAPMPSDAVATRLAAIGAPASTSDADTDADTDADTDTDTDEIAVVGMGVALPGASDPQAFWRALL
NGPELFGNVPPDRWDYRSFYSPDPSAEDKSYQSRSVFIEHFEPETRLRAEIEAGAAPHELTTLWLRHSLRQALDGVRVRA
GDRTSFLVGYTADGSQHLEEGMVLAAMRARLRETLDEAGVPPDERERRIAQIDAVLRARYARGTGELAEYFPHRVGLNAM
RGVLPDDAEYMMVDTACSSSLYSVDLGIKSLLAGQHDVVACGGAFALAPRGSILFSKLHGLSKSGEVRPLDKACDGVLFA
DGAGVVILKRLKRALADGDRVLGVLKAFGSSSDGKGKAIYAPNSAGQSIAIERAYRQTDVRKEAVDWVVAHATGTPAGDL
AEFQSLREKLKGDRPVYVTSNKSLVGHTGWAAGVVSLIQVLLALEHGRIPPQHRFSEPPREFGIESSGFTIPTQAVDWPR
KADAARVAAVSGFGFGGTNGHLIVGEYRPDLSASKPAARVSREPLAIVGWSAKFPALDGRDAIAAWLNGAGPAPGASFGR
AYPLPSFDRVRMPPAVLRALDRCQLMVLDAAHDMREQLRDYWSAHANAIGVVMGHMGPTRNAALYASRCYIDDIATAVRA
RFDDAARAPLDDALARAADRTRSLVPPTTENAFPGMMPNVIPARVANYHDLHGMNMTVDAGHASTLAAFEVASRFLRSGE
LDMVIVGGVNGNSADEVQPAFDQPLAEGIVLFAVTTKAQAEAAGLPALAWIESDRAFADAASAPPAALRDAQGRELTYAG
ADGALAVLRALVGGADAVSVALGNARDQVRFGLRIDRHAPPASGDGGVRSRRVFGDSSSSSATTAATTATTATTTATTTA
TTTATTTATTTATAPVSSHLYASSSVLAAPSATSPTPVAPCSTAVQAARPAPAATIAAEATEAPHAAAARAASVADKRVP
IPATLKATDVAADGEPLGVARYRIDLQETPWHAGAGAIAYLPAGSVVVTDAPELLDGIGMLPADLLVLSTRAAAFSRARL
VVVDTLGETALQGLIPAGTRHVRLLTSLHAGALAPQRLSAPSPERLKLHDLAFLALKQCYDSVAQQGSFIALLLDAVKDD
VLHPDAGMFTGLVKALAIELPHARSLAVLTDDADIRHGVARAERESGAQHLLPVVALCGTRRLTPRVTRDAGELPADGLA
RLGPDSVVVAFGGARGITAELMKALAEHFRPTIYLIGSSALDVHGPEVFAGSDEAFARRRPDYIREQKALDPNLPLPAII
KAFERQVEARAARRNIDVMKSYCGPNKVFYLRADVLDAASVRAAVERIATAGQPIDLVVNAAGLNRSASVNVKSFDDFVA
VRDIKVRGYWNVRAAFGAEQPRAWCNFGSFIGLTGQAGETDYASGNDFLNTQAAYHRAALARDEFTIGWTLWRSVGLGAN
PVTRAFLEKSGLFTSMRTNEGIHHFLREINLAERAASSVHLGAAERRAIEAHLPTFFDAPDAAQAPAMQAPQAAQAQARA
WQAAQASATPQPPHSPHSPQIAPNARIGQAPTPARARIASPPSHDFYLGREVRRTSDSVMFERVFDLRTDAYLQHHVVNR
FATLPGTFVPELAAEAAMKLLPGLRVVGFRDAAFRHFLRVYDAQRPSTKRIHAQVVGREGEAAVVQVRITGDVLAPNGQV
LVQDKLHFEIKALVAPRHPSAPVWPMRPDEPRTPVADPYHFESAPVRLTGMFVSTADTGVTATGKAARYQLNVAADDPVF
SRFVIPSIMLDGLARVAVLNYVANDYIPLAAPVSIGRIDLYEGGNDCELARRYDRIDLYATPRAFALEGAHGGNRFAAVR
PDGRMLMEMGDVSGVVIGYVHRTTGAYATKAEVDALAARLATERETA
>Mature_2286_residues
SNSYLLGKRVLVTGGAKNVGKAICRRFAEEGAHVIINFFHSLDASKQTAAELRALGATVDVVRASVAQPAQVERMFDEIE
AKYGKIDILVNNAASGALLPVDDIEAAHFDRALDTNLKGAFWCARRAARLMARAGGGAIVNVSSVGATLVPANYLVVGTA
KAALESLTRYLAVEYASLGIRVNGASSTLIDGDVAAQFPDPENTKRSSIAATPLGRLATPEDLADVVLFLASDAARWITG
QVIVADGGLSLCSEALSPRREWRGARQTAGGDGALLPDTPDTLAGLAAFPSRASAGAASAAPLAASRDAGPDAFAAGAGS
GAGAGVAVMGTVTQAASGHLRAASGAAGAARAPAAVVHAARAVASQAAEDAAPARVPAVTTTAEIASASRSSGTAPASAA
RVPADAGAAASHGAPAPMPSDAVATRLAAIGAPASTSDADTDADTDADTDTDTDEIAVVGMGVALPGASDPQAFWRALLN
GPELFGNVPPDRWDYRSFYSPDPSAEDKSYQSRSVFIEHFEPETRLRAEIEAGAAPHELTTLWLRHSLRQALDGVRVRAG
DRTSFLVGYTADGSQHLEEGMVLAAMRARLRETLDEAGVPPDERERRIAQIDAVLRARYARGTGELAEYFPHRVGLNAMR
GVLPDDAEYMMVDTACSSSLYSVDLGIKSLLAGQHDVVACGGAFALAPRGSILFSKLHGLSKSGEVRPLDKACDGVLFAD
GAGVVILKRLKRALADGDRVLGVLKAFGSSSDGKGKAIYAPNSAGQSIAIERAYRQTDVRKEAVDWVVAHATGTPAGDLA
EFQSLREKLKGDRPVYVTSNKSLVGHTGWAAGVVSLIQVLLALEHGRIPPQHRFSEPPREFGIESSGFTIPTQAVDWPRK
ADAARVAAVSGFGFGGTNGHLIVGEYRPDLSASKPAARVSREPLAIVGWSAKFPALDGRDAIAAWLNGAGPAPGASFGRA
YPLPSFDRVRMPPAVLRALDRCQLMVLDAAHDMREQLRDYWSAHANAIGVVMGHMGPTRNAALYASRCYIDDIATAVRAR
FDDAARAPLDDALARAADRTRSLVPPTTENAFPGMMPNVIPARVANYHDLHGMNMTVDAGHASTLAAFEVASRFLRSGEL
DMVIVGGVNGNSADEVQPAFDQPLAEGIVLFAVTTKAQAEAAGLPALAWIESDRAFADAASAPPAALRDAQGRELTYAGA
DGALAVLRALVGGADAVSVALGNARDQVRFGLRIDRHAPPASGDGGVRSRRVFGDSSSSSATTAATTATTATTTATTTAT
TTATTTATTTATAPVSSHLYASSSVLAAPSATSPTPVAPCSTAVQAARPAPAATIAAEATEAPHAAAARAASVADKRVPI
PATLKATDVAADGEPLGVARYRIDLQETPWHAGAGAIAYLPAGSVVVTDAPELLDGIGMLPADLLVLSTRAAAFSRARLV
VVDTLGETALQGLIPAGTRHVRLLTSLHAGALAPQRLSAPSPERLKLHDLAFLALKQCYDSVAQQGSFIALLLDAVKDDV
LHPDAGMFTGLVKALAIELPHARSLAVLTDDADIRHGVARAERESGAQHLLPVVALCGTRRLTPRVTRDAGELPADGLAR
LGPDSVVVAFGGARGITAELMKALAEHFRPTIYLIGSSALDVHGPEVFAGSDEAFARRRPDYIREQKALDPNLPLPAIIK
AFERQVEARAARRNIDVMKSYCGPNKVFYLRADVLDAASVRAAVERIATAGQPIDLVVNAAGLNRSASVNVKSFDDFVAV
RDIKVRGYWNVRAAFGAEQPRAWCNFGSFIGLTGQAGETDYASGNDFLNTQAAYHRAALARDEFTIGWTLWRSVGLGANP
VTRAFLEKSGLFTSMRTNEGIHHFLREINLAERAASSVHLGAAERRAIEAHLPTFFDAPDAAQAPAMQAPQAAQAQARAW
QAAQASATPQPPHSPHSPQIAPNARIGQAPTPARARIASPPSHDFYLGREVRRTSDSVMFERVFDLRTDAYLQHHVVNRF
ATLPGTFVPELAAEAAMKLLPGLRVVGFRDAAFRHFLRVYDAQRPSTKRIHAQVVGREGEAAVVQVRITGDVLAPNGQVL
VQDKLHFEIKALVAPRHPSAPVWPMRPDEPRTPVADPYHFESAPVRLTGMFVSTADTGVTATGKAARYQLNVAADDPVFS
RFVIPSIMLDGLARVAVLNYVANDYIPLAAPVSIGRIDLYEGGNDCELARRYDRIDLYATPRAFALEGAHGGNRFAAVRP
DGRMLMEMGDVSGVVIGYVHRTTGAYATKAEVDALAARLATERETA

Specific function: 7-Alpha-Dehydroxylation Of Cholic Acid, Yielding Deoxycholic Acid And Lithocholic Acid, Respectively. Highest Affinity With Taurochenodeoxycholic Acid. [C]

COG id: COG3321

COG function: function code Q; Polyketide synthase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=33.6032388663968, Blast_Score=114, Evalue=1e-24,
Organism=Homo sapiens, GI41872631, Length=262, Percent_Identity=33.206106870229, Blast_Score=113, Evalue=2e-24,
Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=32.8185328185328, Blast_Score=112, Evalue=4e-24,
Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=32.6530612244898, Blast_Score=110, Evalue=2e-23,
Organism=Homo sapiens, GI7705925, Length=254, Percent_Identity=32.2834645669291, Blast_Score=110, Evalue=2e-23,
Organism=Homo sapiens, GI8923559, Length=297, Percent_Identity=25.9259259259259, Blast_Score=92, Evalue=5e-18,
Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=29.2682926829268, Blast_Score=90, Evalue=3e-17,
Organism=Homo sapiens, GI4503301, Length=210, Percent_Identity=30, Blast_Score=89, Evalue=7e-17,
Organism=Homo sapiens, GI59889578, Length=234, Percent_Identity=30.3418803418803, Blast_Score=84, Evalue=2e-15,
Organism=Homo sapiens, GI126723750, Length=249, Percent_Identity=28.5140562248996, Blast_Score=82, Evalue=4e-15,
Organism=Homo sapiens, GI66933014, Length=253, Percent_Identity=28.4584980237154, Blast_Score=82, Evalue=8e-15,
Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=29.6747967479675, Blast_Score=76, Evalue=4e-13,
Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=27.6264591439689, Blast_Score=76, Evalue=4e-13,
Organism=Homo sapiens, GI209862901, Length=169, Percent_Identity=30.7692307692308, Blast_Score=75, Evalue=5e-13,
Organism=Homo sapiens, GI19923983, Length=169, Percent_Identity=30.7692307692308, Blast_Score=75, Evalue=5e-13,
Organism=Homo sapiens, GI126723191, Length=183, Percent_Identity=32.7868852459016, Blast_Score=74, Evalue=2e-12,
Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=33.1983805668016, Blast_Score=121, Evalue=7e-28,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=34.2857142857143, Blast_Score=119, Evalue=2e-27,
Organism=Escherichia coli, GI87082100, Length=258, Percent_Identity=35.6589147286822, Blast_Score=113, Evalue=2e-25,
Organism=Escherichia coli, GI1787335, Length=251, Percent_Identity=32.2709163346614, Blast_Score=111, Evalue=6e-25,
Organism=Escherichia coli, GI1788663, Length=258, Percent_Identity=29.0697674418605, Blast_Score=107, Evalue=9e-24,
Organism=Escherichia coli, GI1788459, Length=254, Percent_Identity=27.5590551181102, Blast_Score=102, Evalue=3e-22,
Organism=Escherichia coli, GI87082160, Length=245, Percent_Identity=29.3877551020408, Blast_Score=101, Evalue=5e-22,
Organism=Escherichia coli, GI1787337, Length=258, Percent_Identity=32.5581395348837, Blast_Score=100, Evalue=1e-21,
Organism=Escherichia coli, GI1786812, Length=254, Percent_Identity=33.0708661417323, Blast_Score=94, Evalue=1e-19,
Organism=Escherichia coli, GI1787545, Length=257, Percent_Identity=31.9066147859922, Blast_Score=91, Evalue=7e-19,
Organism=Escherichia coli, GI1790717, Length=245, Percent_Identity=24.8979591836735, Blast_Score=90, Evalue=1e-18,
Organism=Escherichia coli, GI1789208, Length=253, Percent_Identity=30.4347826086957, Blast_Score=89, Evalue=3e-18,
Organism=Escherichia coli, GI2367365, Length=244, Percent_Identity=31.5573770491803, Blast_Score=89, Evalue=5e-18,
Organism=Escherichia coli, GI1789057, Length=263, Percent_Identity=28.8973384030418, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1789378, Length=249, Percent_Identity=25.3012048192771, Blast_Score=75, Evalue=5e-14,
Organism=Escherichia coli, GI1787820, Length=231, Percent_Identity=26.8398268398268, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17550940, Length=312, Percent_Identity=31.4102564102564, Blast_Score=129, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI212642053, Length=257, Percent_Identity=30.7392996108949, Blast_Score=115, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17561402, Length=251, Percent_Identity=33.0677290836653, Blast_Score=106, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17536651, Length=260, Percent_Identity=30.3846153846154, Blast_Score=106, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=32.824427480916, Blast_Score=103, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI115534694, Length=248, Percent_Identity=34.2741935483871, Blast_Score=103, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17536025, Length=265, Percent_Identity=30.5660377358491, Blast_Score=102, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17544670, Length=277, Percent_Identity=29.6028880866426, Blast_Score=102, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=31.8181818181818, Blast_Score=101, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71983535, Length=258, Percent_Identity=27.1317829457364, Blast_Score=100, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17560332, Length=271, Percent_Identity=34.3173431734317, Blast_Score=100, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71983541, Length=258, Percent_Identity=27.1317829457364, Blast_Score=100, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=31.9391634980989, Blast_Score=98, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17561272, Length=237, Percent_Identity=29.535864978903, Blast_Score=98, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=31.4393939393939, Blast_Score=97, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17563726, Length=275, Percent_Identity=30.9090909090909, Blast_Score=97, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=30.5343511450382, Blast_Score=96, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=31.6793893129771, Blast_Score=96, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17560676, Length=251, Percent_Identity=30.2788844621514, Blast_Score=96, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17531453, Length=275, Percent_Identity=30.1818181818182, Blast_Score=95, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=30.1526717557252, Blast_Score=94, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=30.9433962264151, Blast_Score=93, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17565030, Length=272, Percent_Identity=33.4558823529412, Blast_Score=91, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI193204405, Length=260, Percent_Identity=30, Blast_Score=91, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=29.9242424242424, Blast_Score=89, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=269, Percent_Identity=31.2267657992565, Blast_Score=88, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17555706, Length=251, Percent_Identity=27.8884462151394, Blast_Score=87, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=276, Percent_Identity=29.3478260869565, Blast_Score=79, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=270, Percent_Identity=30, Blast_Score=79, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=27.2, Blast_Score=76, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=246, Percent_Identity=26.4227642276423, Blast_Score=74, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17538182, Length=254, Percent_Identity=26.7716535433071, Blast_Score=72, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=253, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=252, Percent_Identity=28.968253968254, Blast_Score=88, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320904, Length=260, Percent_Identity=25.7692307692308, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21355319, Length=247, Percent_Identity=33.6032388663968, Blast_Score=124, Evalue=1e-27,
Organism=Drosophila melanogaster, GI221330659, Length=257, Percent_Identity=30.7392996108949, Blast_Score=120, Evalue=1e-26,
Organism=Drosophila melanogaster, GI19920632, Length=257, Percent_Identity=30.7392996108949, Blast_Score=119, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24639444, Length=262, Percent_Identity=33.969465648855, Blast_Score=105, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24581345, Length=487, Percent_Identity=23.8193018480493, Blast_Score=103, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24644341, Length=264, Percent_Identity=29.9242424242424, Blast_Score=102, Evalue=3e-21,
Organism=Drosophila melanogaster, GI23397609, Length=264, Percent_Identity=32.1969696969697, Blast_Score=102, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24644339, Length=258, Percent_Identity=30.6201550387597, Blast_Score=100, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24643142, Length=253, Percent_Identity=31.2252964426877, Blast_Score=91, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28571526, Length=260, Percent_Identity=30.7692307692308, Blast_Score=91, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21357041, Length=263, Percent_Identity=28.8973384030418, Blast_Score=87, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24644337, Length=209, Percent_Identity=27.7511961722488, Blast_Score=78, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.10 [H]

Molecular weight: Translated: 240394; Mature: 240262

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSYLLGKRVLVTGGAKNVGKAICRRFAEEGAHVIINFFHSLDASKQTAAELRALGATV
CCCCEEECCEEEEECCCHHHHHHHHHHHHHCCCEEEHHHHHHCCCCHHHHHHHHHHCCHH
DVVRASVAQPAQVERMFDEIEAKYGKIDILVNNAASGALLPVDDIEAAHFDRALDTNLKG
HHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHCCCHHHHHHHHCCCCCH
AFWCARRAARLMARAGGGAIVNVSSVGATLVPANYLVVGTAKAALESLTRYLAVEYASLG
HHHHHHHHHHHHHHCCCCEEEEECCCCCEEECCCEEEEECHHHHHHHHHHHHHHHHHHEE
IRVNGASSTLIDGDVAAQFPDPENTKRSSIAATPLGRLATPEDLADVVLFLASDAARWIT
EEECCCCCEEECCCEEECCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHCCCHHHEE
GQVIVADGGLSLCSEALSPRREWRGARQTAGGDGALLPDTPDTLAGLAAFPSRASAGAAS
CEEEEECCCHHHHHHHHCCHHHHCCHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCC
AAPLAASRDAGPDAFAAGAGSGAGAGVAVMGTVTQAASGHLRAASGAAGAARAPAAVVHA
CCCCCCCCCCCCCHHHCCCCCCCCCCEEEEEHHHHHCCCCEEECCCCCCCCCCHHHHHHH
ARAVASQAAEDAAPARVPAVTTTAEIASASRSSGTAPASAARVPADAGAAASHGAPAPMP
HHHHHHHHHHHCCCCCCCCEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SDAVATRLAAIGAPASTSDADTDADTDADTDTDTDEIAVVGMGVALPGASDPQAFWRALL
CHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHH
NGPELFGNVPPDRWDYRSFYSPDPSAEDKSYQSRSVFIEHFEPETRLRAEIEAGAAPHEL
CCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEEEEECCCCHHHHHHHHCCCCCHHH
TTLWLRHSLRQALDGVRVRAGDRTSFLVGYTADGSQHLEEGMVLAAMRARLRETLDEAGV
HHHHHHHHHHHHHCCCEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PPDERERRIAQIDAVLRARYARGTGELAEYFPHRVGLNAMRGVLPDDAEYMMVDTACSSS
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHCHHHCCHHHHHCCCCCCCCEEEEECHHCCC
LYSVDLGIKSLLAGQHDVVACGGAFALAPRGSILFSKLHGLSKSGEVRPLDKACDGVLFA
EEEEHHHHHHHHCCCCCEEEECCEEEECCCCHHHHHHHHCCCCCCCCCCHHHHHCCEEEE
DGAGVVILKRLKRALADGDRVLGVLKAFGSSSDGKGKAIYAPNSAGQSIAIERAYRQTDV
CCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHH
RKEAVDWVVAHATGTPAGDLAEFQSLREKLKGDRPVYVTSNKSLVGHTGWAAGVVSLIQV
HHHHHHEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCEECCCCHHHHHHHHHHH
LLALEHGRIPPQHRFSEPPREFGIESSGFTIPTQAVDWPRKADAARVAAVSGFGFGGTNG
HHHHHCCCCCCHHCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHEEEEECCCCCCCCC
HLIVGEYRPDLSASKPAARVSREPLAIVGWSAKFPALDGRDAIAAWLNGAGPAPGASFGR
CEEEECCCCCCCCCCCHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCC
AYPLPSFDRVRMPPAVLRALDRCQLMVLDAAHDMREQLRDYWSAHANAIGVVMGHMGPTR
CCCCCCCCCCCCCHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCC
NAALYASRCYIDDIATAVRARFDDAARAPLDDALARAADRTRSLVPPTTENAFPGMMPNV
CCEEEEHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCH
IPARVANYHDLHGMNMTVDAGHASTLAAFEVASRFLRSGELDMVIVGGVNGNSADEVQPA
HHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCH
FDQPLAEGIVLFAVTTKAQAEAAGLPALAWIESDRAFADAASAPPAALRDAQGRELTYAG
HCCHHHCCEEEEEEECCCHHHHCCCCEEEEEECCCHHHHCCCCCCHHHHCCCCCEEEEEC
ADGALAVLRALVGGADAVSVALGNARDQVRFGLRIDRHAPPASGDGGVRSRRVFGDSSSS
CCHHHHHHHHHHCCCCEEEEECCCCHHHEEECEEEECCCCCCCCCCCCCCEEEECCCCCC
SATTAATTATTATTTATTTATTTATTTATTTATAPVSSHLYASSSVLAAPSATSPTPVAP
CCCEEEEECCCCCCEEEEEEEEEEEEEECCEECCCCHHHHCCCCCEEECCCCCCCCCCCC
CSTAVQAARPAPAATIAAEATEAPHAAAARAASVADKRVPIPATLKATDVAADGEPLGVA
HHHHHHHCCCCCCCEEEHHCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCEEE
RYRIDLQETPWHAGAGAIAYLPAGSVVVTDAPELLDGIGMLPADLLVLSTRAAAFSRARL
EEEEECCCCCCCCCCCEEEEECCCCEEEECCHHHHHHCCCCHHHHHHHHHHHHHHHCCEE
VVVDTLGETALQGLIPAGTRHVRLLTSLHAGALAPQRLSAPSPERLKLHDLAFLALKQCY
EEEECCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHCCCCCCCCEEHHHHHHHHHHHHH
DSVAQQGSFIALLLDAVKDDVLHPDAGMFTGLVKALAIELPHARSLAVLTDDADIRHGVA
HHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHH
RAERESGAQHLLPVVALCGTRRLTPRVTRDAGELPADGLARLGPDSVVVAFGGARGITAE
HHHHHCCHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCHHHHCCCCCEEEEECCCCCCHHH
LMKALAEHFRPTIYLIGSSALDVHGPEVFAGSDEAFARRRPDYIREQKALDPNLPLPAII
HHHHHHHHCCCEEEEEECCEEECCCCEEECCCCHHHHHCCCHHHHHHHCCCCCCCHHHHH
KAFERQVEARAARRNIDVMKSYCGPNKVFYLRADVLDAASVRAAVERIATAGQPIDLVVN
HHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHCCCCEEEEEE
AAGLNRSASVNVKSFDDFVAVRDIKVRGYWNVRAAFGAEQPRAWCNFGSFIGLTGQAGET
ECCCCCCCEEEECCCCCEEEEEEEEEEEEEEEEECCCCCCCHHHHCCCCEEECCCCCCCC
DYASGNDFLNTQAAYHRAALARDEFTIGWTLWRSVGLGANPVTRAFLEKSGLFTSMRTNE
CCCCCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHCCCCCCHHHHHHHHHCCCEEEHHCCH
GIHHFLREINLAERAASSVHLGAAERRAIEAHLPTFFDAPDAAQAPAMQAPQAAQAQARA
HHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHH
WQAAQASATPQPPHSPHSPQIAPNARIGQAPTPARARIASPPSHDFYLGREVRRTSDSVM
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHH
FERVFDLRTDAYLQHHVVNRFATLPGTFVPELAAEAAMKLLPGLRVVGFRDAAFRHFLRV
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHH
YDAQRPSTKRIHAQVVGREGEAAVVQVRITGDVLAPNGQVLVQDKLHFEIKALVAPRHPS
HHCCCCCCCEEEEEEECCCCCEEEEEEEEECCEECCCCCEEEECCCCEEEEEEECCCCCC
APVWPMRPDEPRTPVADPYHFESAPVRLTGMFVSTADTGVTATGKAARYQLNVAADDPVF
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCEECCCCEEEEEEECCCCCHH
SRFVIPSIMLDGLARVAVLNYVANDYIPLAAPVSIGRIDLYEGGNDCELARRYDRIDLYA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHCCCEEEEE
TPRAFALEGAHGGNRFAAVRPDGRMLMEMGDVSGVVIGYVHRTTGAYATKAEVDALAARL
CCCEEEEECCCCCCEEEEECCCCCEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHH
ATERETA
HHHCCCC
>Mature Secondary Structure 
SNSYLLGKRVLVTGGAKNVGKAICRRFAEEGAHVIINFFHSLDASKQTAAELRALGATV
CCCEEECCEEEEECCCHHHHHHHHHHHHHCCCEEEHHHHHHCCCCHHHHHHHHHHCCHH
DVVRASVAQPAQVERMFDEIEAKYGKIDILVNNAASGALLPVDDIEAAHFDRALDTNLKG
HHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHCCCHHHHHHHHCCCCCH
AFWCARRAARLMARAGGGAIVNVSSVGATLVPANYLVVGTAKAALESLTRYLAVEYASLG
HHHHHHHHHHHHHHCCCCEEEEECCCCCEEECCCEEEEECHHHHHHHHHHHHHHHHHHEE
IRVNGASSTLIDGDVAAQFPDPENTKRSSIAATPLGRLATPEDLADVVLFLASDAARWIT
EEECCCCCEEECCCEEECCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHCCCHHHEE
GQVIVADGGLSLCSEALSPRREWRGARQTAGGDGALLPDTPDTLAGLAAFPSRASAGAAS
CEEEEECCCHHHHHHHHCCHHHHCCHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCC
AAPLAASRDAGPDAFAAGAGSGAGAGVAVMGTVTQAASGHLRAASGAAGAARAPAAVVHA
CCCCCCCCCCCCCHHHCCCCCCCCCCEEEEEHHHHHCCCCEEECCCCCCCCCCHHHHHHH
ARAVASQAAEDAAPARVPAVTTTAEIASASRSSGTAPASAARVPADAGAAASHGAPAPMP
HHHHHHHHHHHCCCCCCCCEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SDAVATRLAAIGAPASTSDADTDADTDADTDTDTDEIAVVGMGVALPGASDPQAFWRALL
CHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHH
NGPELFGNVPPDRWDYRSFYSPDPSAEDKSYQSRSVFIEHFEPETRLRAEIEAGAAPHEL
CCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEEEEECCCCHHHHHHHHCCCCCHHH
TTLWLRHSLRQALDGVRVRAGDRTSFLVGYTADGSQHLEEGMVLAAMRARLRETLDEAGV
HHHHHHHHHHHHHCCCEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PPDERERRIAQIDAVLRARYARGTGELAEYFPHRVGLNAMRGVLPDDAEYMMVDTACSSS
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHCHHHCCHHHHHCCCCCCCCEEEEECHHCCC
LYSVDLGIKSLLAGQHDVVACGGAFALAPRGSILFSKLHGLSKSGEVRPLDKACDGVLFA
EEEEHHHHHHHHCCCCCEEEECCEEEECCCCHHHHHHHHCCCCCCCCCCHHHHHCCEEEE
DGAGVVILKRLKRALADGDRVLGVLKAFGSSSDGKGKAIYAPNSAGQSIAIERAYRQTDV
CCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHH
RKEAVDWVVAHATGTPAGDLAEFQSLREKLKGDRPVYVTSNKSLVGHTGWAAGVVSLIQV
HHHHHHEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCEECCCCHHHHHHHHHHH
LLALEHGRIPPQHRFSEPPREFGIESSGFTIPTQAVDWPRKADAARVAAVSGFGFGGTNG
HHHHHCCCCCCHHCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHEEEEECCCCCCCCC
HLIVGEYRPDLSASKPAARVSREPLAIVGWSAKFPALDGRDAIAAWLNGAGPAPGASFGR
CEEEECCCCCCCCCCCHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCC
AYPLPSFDRVRMPPAVLRALDRCQLMVLDAAHDMREQLRDYWSAHANAIGVVMGHMGPTR
CCCCCCCCCCCCCHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCC
NAALYASRCYIDDIATAVRARFDDAARAPLDDALARAADRTRSLVPPTTENAFPGMMPNV
CCEEEEHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCH
IPARVANYHDLHGMNMTVDAGHASTLAAFEVASRFLRSGELDMVIVGGVNGNSADEVQPA
HHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCH
FDQPLAEGIVLFAVTTKAQAEAAGLPALAWIESDRAFADAASAPPAALRDAQGRELTYAG
HCCHHHCCEEEEEEECCCHHHHCCCCEEEEEECCCHHHHCCCCCCHHHHCCCCCEEEEEC
ADGALAVLRALVGGADAVSVALGNARDQVRFGLRIDRHAPPASGDGGVRSRRVFGDSSSS
CCHHHHHHHHHHCCCCEEEEECCCCHHHEEECEEEECCCCCCCCCCCCCCEEEECCCCCC
SATTAATTATTATTTATTTATTTATTTATTTATAPVSSHLYASSSVLAAPSATSPTPVAP
CCCEEEEECCCCCCEEEEEEEEEEEEEECCEECCCCHHHHCCCCCEEECCCCCCCCCCCC
CSTAVQAARPAPAATIAAEATEAPHAAAARAASVADKRVPIPATLKATDVAADGEPLGVA
HHHHHHHCCCCCCCEEEHHCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCEEE
RYRIDLQETPWHAGAGAIAYLPAGSVVVTDAPELLDGIGMLPADLLVLSTRAAAFSRARL
EEEEECCCCCCCCCCCEEEEECCCCEEEECCHHHHHHCCCCHHHHHHHHHHHHHHHCCEE
VVVDTLGETALQGLIPAGTRHVRLLTSLHAGALAPQRLSAPSPERLKLHDLAFLALKQCY
EEEECCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHCCCCCCCCEEHHHHHHHHHHHHH
DSVAQQGSFIALLLDAVKDDVLHPDAGMFTGLVKALAIELPHARSLAVLTDDADIRHGVA
HHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHH
RAERESGAQHLLPVVALCGTRRLTPRVTRDAGELPADGLARLGPDSVVVAFGGARGITAE
HHHHHCCHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCHHHHCCCCCEEEEECCCCCCHHH
LMKALAEHFRPTIYLIGSSALDVHGPEVFAGSDEAFARRRPDYIREQKALDPNLPLPAII
HHHHHHHHCCCEEEEEECCEEECCCCEEECCCCHHHHHCCCHHHHHHHCCCCCCCHHHHH
KAFERQVEARAARRNIDVMKSYCGPNKVFYLRADVLDAASVRAAVERIATAGQPIDLVVN
HHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHCCCCEEEEEE
AAGLNRSASVNVKSFDDFVAVRDIKVRGYWNVRAAFGAEQPRAWCNFGSFIGLTGQAGET
ECCCCCCCEEEECCCCCEEEEEEEEEEEEEEEEECCCCCCCHHHHCCCCEEECCCCCCCC
DYASGNDFLNTQAAYHRAALARDEFTIGWTLWRSVGLGANPVTRAFLEKSGLFTSMRTNE
CCCCCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHCCCCCCHHHHHHHHHCCCEEEHHCCH
GIHHFLREINLAERAASSVHLGAAERRAIEAHLPTFFDAPDAAQAPAMQAPQAAQAQARA
HHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHH
WQAAQASATPQPPHSPHSPQIAPNARIGQAPTPARARIASPPSHDFYLGREVRRTSDSVM
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHH
FERVFDLRTDAYLQHHVVNRFATLPGTFVPELAAEAAMKLLPGLRVVGFRDAAFRHFLRV
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHH
YDAQRPSTKRIHAQVVGREGEAAVVQVRITGDVLAPNGQVLVQDKLHFEIKALVAPRHPS
HHCCCCCCCEEEEEEECCCCCEEEEEEEEECCEECCCCCEEEECCCCEEEEEEECCCCCC
APVWPMRPDEPRTPVADPYHFESAPVRLTGMFVSTADTGVTATGKAARYQLNVAADDPVF
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCEECCCCEEEEEEECCCCCHH
SRFVIPSIMLDGLARVAVLNYVANDYIPLAAPVSIGRIDLYEGGNDCELARRYDRIDLYA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHCCCEEEEE
TPRAFALEGAHGGNRFAAVRPDGRMLMEMGDVSGVVIGYVHRTTGAYATKAEVDALAARL
CCCEEEEECCCCCCEEEEECCCCCEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHH
ATERETA
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8946165; 9202460; 9384377 [H]