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The map label for this gene is tctE [H]

Identifier: 126447126

GI number: 126447126

Start: 1451730

End: 1453235

Strand: Reverse

Name: tctE [H]

Synonym: BMA10247_A1500

Alternate gene names: 126447126

Gene position: 1453235-1451730 (Counterclockwise)

Preceding gene: 126446503

Following gene: 126446854

Centisome position: 61.77

GC content: 72.91

Gene sequence:

>1506_bases
GTGACGCGGCTCAATCTGCGCGCGCAGGTCGCGTTATGGTTGCTGCTGCCGTTCCTCGGGCTGCTCGCGCTCGATTCGTG
GCTCACGTACCAGCGCGCGATGAACGCCGCGCACGTCGCGTTCGATCGCACGCTCGCGTCGTCGCTGAAGTCGATCCGCG
AGGGCGTGCGGCTCGTCGGCGGCGAGGTCGAGGTCGATCTGCCGTATCTCGCGCTCGAGATGTTCGAGTCGAACGACGGC
GGCAAGATCTACTACCTGATTCGCGGCGACGACGGCCGCGCGGTCACCGGCTACCGCGATCTGCCGATGCCGGGCGCGGG
CGCGCCGCTCTATGCGACGTCGTTCTACGACGCCGTGTATCGCGGCGAGCAGTTGCGCATGGCCGCGCTGCGGCTGCCCG
TGCACGACGTGCCGAGCGCGCGGACGCGCGTCGTGTGGGTGATGGTCGGCGAGACGATCGAGGCGCGGCAGGCGCTCGCG
CGCGAGATCCTGGTTGGCTCGCTGCTGCAGGAGGGCCTGCTCGTCGTGCTCGCGCTCGGCATCGTGTGGCTCGGCGTCGG
GCGCGGGCTGCGGCCGCTGAACCGGCTGTCCGCGAAGGTCGCCGCGCGCGCGGAGGACGACCCGACGCCGCTCGAGACGC
TCGGGCTGCCGAGCGAGGTCGCGCCGCTCGTCGAATCGATCAACCAGTACGTCGCGCGCACGCAGCGCATGCAGGTCGCG
CGGCGGCGCTTCTTCGCCGACGCCGCGCATCAGCTGAAGACGCCGCTCGCGGCCGCGCAGGCGGGCGTCGAGCTTGCGCT
GCGGCCCGCCGAGCGCGAGCGCGTGAGCGTGCATCTGCGGCGCGTGAACGGCGCGGTGCGGCAGGCGGCGAAGATCGTCC
AGCAGTTGCTGTCGCTGTCGCGGCTCGAATCGGACGTCGCGCCGGCGATCGAGCGCAAGCCGGTCGCGCTCGCGAAGCTC
GCGCGCAGCGTGACGCTCGACTGGTCGGGCGTCGCCCGCGCGCGCGGCATCGATCTCGGCTTCGAGCAGCGCGCGAGCGT
CGACGTGATGGGGCGCGCGGATCTGCTGGGCGAGCTCGTCGGCAACTTGATCGACAACGCGATCCGCTATGCGGGCGACG
GCGCGGTGATCACCGTGCGTGTCGCGCGCGAAGGCGCGCTCGCGCGGCTCGAGGTGATCGACGACGGGCCGGGGATCGCA
CCCGGCGAGCGCGACGCGGTGTTCGAGCGCTTCTACCGGAGTCACGCGACGCTCGCGGTCGAGGGCACGGGGCTCGGGCT
GTCGATCGTGCGCGAGATCGCGCGCGTGCATCGGGGCGCGGTCGAATTGGATGATGCGGCGCTCGCGGGCGGGGCAGCGG
GCGATGCGGGCGACAGAGCCGGTGAGAGGCGTGAAAGAGGCGAGGCGGACCGGCGCGGCGACAGTGACGGCGAGCGCTCG
GCTGAACGGCCGGCGCGCGGGCGCGGGCTCGTCGTGCGCGTGACGCTGCCGGCGCTCGCGGTGTGA

Upstream 100 bases:

>100_bases
TCGAGATCTACGTGCACCGGCTGCGCAAGAAGCTCGAGGGCAGCGGCGTCGCGATCGTCACGCTGCGCGGGCTCGGCTAC
CTGCTCGAGGCGCAGCCGTC

Downstream 100 bases:

>100_bases
ACGCCCGGAGAAACGGGCGGCGGAACGGAACGGGTGGCGGGACGGGCGGCGAGGGCGGCGATGACACGGCCGGGTCGACA
GTTTCAAGCCGGTGCGGGGG

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 501; Mature: 500

Protein sequence:

>501_residues
MTRLNLRAQVALWLLLPFLGLLALDSWLTYQRAMNAAHVAFDRTLASSLKSIREGVRLVGGEVEVDLPYLALEMFESNDG
GKIYYLIRGDDGRAVTGYRDLPMPGAGAPLYATSFYDAVYRGEQLRMAALRLPVHDVPSARTRVVWVMVGETIEARQALA
REILVGSLLQEGLLVVLALGIVWLGVGRGLRPLNRLSAKVAARAEDDPTPLETLGLPSEVAPLVESINQYVARTQRMQVA
RRRFFADAAHQLKTPLAAAQAGVELALRPAERERVSVHLRRVNGAVRQAAKIVQQLLSLSRLESDVAPAIERKPVALAKL
ARSVTLDWSGVARARGIDLGFEQRASVDVMGRADLLGELVGNLIDNAIRYAGDGAVITVRVAREGALARLEVIDDGPGIA
PGERDAVFERFYRSHATLAVEGTGLGLSIVREIARVHRGAVELDDAALAGGAAGDAGDRAGERRERGEADRRGDSDGERS
AERPARGRGLVVRVTLPALAV

Sequences:

>Translated_501_residues
MTRLNLRAQVALWLLLPFLGLLALDSWLTYQRAMNAAHVAFDRTLASSLKSIREGVRLVGGEVEVDLPYLALEMFESNDG
GKIYYLIRGDDGRAVTGYRDLPMPGAGAPLYATSFYDAVYRGEQLRMAALRLPVHDVPSARTRVVWVMVGETIEARQALA
REILVGSLLQEGLLVVLALGIVWLGVGRGLRPLNRLSAKVAARAEDDPTPLETLGLPSEVAPLVESINQYVARTQRMQVA
RRRFFADAAHQLKTPLAAAQAGVELALRPAERERVSVHLRRVNGAVRQAAKIVQQLLSLSRLESDVAPAIERKPVALAKL
ARSVTLDWSGVARARGIDLGFEQRASVDVMGRADLLGELVGNLIDNAIRYAGDGAVITVRVAREGALARLEVIDDGPGIA
PGERDAVFERFYRSHATLAVEGTGLGLSIVREIARVHRGAVELDDAALAGGAAGDAGDRAGERRERGEADRRGDSDGERS
AERPARGRGLVVRVTLPALAV
>Mature_500_residues
TRLNLRAQVALWLLLPFLGLLALDSWLTYQRAMNAAHVAFDRTLASSLKSIREGVRLVGGEVEVDLPYLALEMFESNDGG
KIYYLIRGDDGRAVTGYRDLPMPGAGAPLYATSFYDAVYRGEQLRMAALRLPVHDVPSARTRVVWVMVGETIEARQALAR
EILVGSLLQEGLLVVLALGIVWLGVGRGLRPLNRLSAKVAARAEDDPTPLETLGLPSEVAPLVESINQYVARTQRMQVAR
RRFFADAAHQLKTPLAAAQAGVELALRPAERERVSVHLRRVNGAVRQAAKIVQQLLSLSRLESDVAPAIERKPVALAKLA
RSVTLDWSGVARARGIDLGFEQRASVDVMGRADLLGELVGNLIDNAIRYAGDGAVITVRVAREGALARLEVIDDGPGIAP
GERDAVFERFYRSHATLAVEGTGLGLSIVREIARVHRGAVELDDAALAGGAAGDAGDRAGERRERGEADRRGDSDGERSA
ERPARGRGLVVRVTLPALAV

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=326, Percent_Identity=37.4233128834356, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1788393, Length=254, Percent_Identity=29.9212598425197, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI87082128, Length=240, Percent_Identity=32.0833333333333, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1786783, Length=304, Percent_Identity=26.9736842105263, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1790551, Length=304, Percent_Identity=29.6052631578947, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786600, Length=226, Percent_Identity=30.5309734513274, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1790346, Length=239, Percent_Identity=29.7071129707113, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1790861, Length=300, Percent_Identity=29, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787374, Length=278, Percent_Identity=26.2589928057554, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788279, Length=332, Percent_Identity=24.0963855421687, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1789808, Length=285, Percent_Identity=27.3684210526316, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1786912, Length=224, Percent_Identity=29.0178571428571, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1787894, Length=236, Percent_Identity=28.3898305084746, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790436, Length=212, Percent_Identity=28.3018867924528, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788713, Length=220, Percent_Identity=22.7272727272727, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI145693157, Length=224, Percent_Identity=23.2142857142857, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1789149, Length=235, Percent_Identity=23.8297872340426, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI48994928, Length=204, Percent_Identity=25.4901960784314, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54111; Mature: 53980

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRLNLRAQVALWLLLPFLGLLALDSWLTYQRAMNAAHVAFDRTLASSLKSIREGVRLVG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GEVEVDLPYLALEMFESNDGGKIYYLIRGDDGRAVTGYRDLPMPGAGAPLYATSFYDAVY
CEEEECCHHHHHHHHCCCCCCEEEEEEECCCCCEECCCCCCCCCCCCCCCHHHHHHHHHH
RGEQLRMAALRLPVHDVPSARTRVVWVMVGETIEARQALAREILVGSLLQEGLLVVLALG
CCCHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVWLGVGRGLRPLNRLSAKVAARAEDDPTPLETLGLPSEVAPLVESINQYVARTQRMQVA
HHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
RRRFFADAAHQLKTPLAAAQAGVELALRPAERERVSVHLRRVNGAVRQAAKIVQQLLSLS
HHHHHHHHHHHHHCHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLESDVAPAIERKPVALAKLARSVTLDWSGVARARGIDLGFEQRASVDVMGRADLLGELV
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCEEECCHHHHHHHHH
GNLIDNAIRYAGDGAVITVRVAREGALARLEVIDDGPGIAPGERDAVFERFYRSHATLAV
HHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEE
EGTGLGLSIVREIARVHRGAVELDDAALAGGAAGDAGDRAGERRERGEADRRGDSDGERS
ECCCCCHHHHHHHHHHHCCCCEECCHHHCCCCCCCCCCCCCHHHHCCCHHCCCCCCCHHH
AERPARGRGLVVRVTLPALAV
HCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
TRLNLRAQVALWLLLPFLGLLALDSWLTYQRAMNAAHVAFDRTLASSLKSIREGVRLVG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GEVEVDLPYLALEMFESNDGGKIYYLIRGDDGRAVTGYRDLPMPGAGAPLYATSFYDAVY
CEEEECCHHHHHHHHCCCCCCEEEEEEECCCCCEECCCCCCCCCCCCCCCHHHHHHHHHH
RGEQLRMAALRLPVHDVPSARTRVVWVMVGETIEARQALAREILVGSLLQEGLLVVLALG
CCCHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVWLGVGRGLRPLNRLSAKVAARAEDDPTPLETLGLPSEVAPLVESINQYVARTQRMQVA
HHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
RRRFFADAAHQLKTPLAAAQAGVELALRPAERERVSVHLRRVNGAVRQAAKIVQQLLSLS
HHHHHHHHHHHHHCHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLESDVAPAIERKPVALAKLARSVTLDWSGVARARGIDLGFEQRASVDVMGRADLLGELV
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCEEECCHHHHHHHHH
GNLIDNAIRYAGDGAVITVRVAREGALARLEVIDDGPGIAPGERDAVFERFYRSHATLAV
HHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEE
EGTGLGLSIVREIARVHRGAVELDDAALAGGAAGDAGDRAGERRERGEADRRGDSDGERS
ECCCCCHHHHHHHHHHHCCCCEECCHHHCCCCCCCCCCCCCHHHHCCCHHCCCCCCCHHH
AERPARGRGLVVRVTLPALAV
HCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]